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iNOS in Medical News

Genetic analysis may predict risk of invasive bladder cancer

...G therapy, the current treatment standard for non-muscle invasive bladder cancer. If a patient had a genotype containing the variant allele of the inos gene, there was a significant reduction in the risk of recurrence compared with those patients who did not have this variance. "Survival associate...

Genetic variants predict recurrence of bladder cancer, patient survival

...ame treatment. The results suggest that BCG may be more effective when administered to individuals with genotypes containing the variant allele of the inos gene. "We aimed to determine why some patients respond to BCG and others don't," said lead author Hushan Yang, Ph.D., a postdoctoral fellow in the ...

What is the mechanism of the chronic radiation enteritis?

...ed radiation induced elevated expression of IL-1beta, TNF alpha, MCP-1, and inos in distal colonic mucosa during the early post-irradiation phase. At that t...ghout the irradiation protocol. After 6 mo, despite the 2-fold reduction of inos and MCP-1 levels, the Th2 profile persisted, as shown by a 50% reduction in...

In blood vessel stents, innovative materials allow better control, delivery of gene therapy

...or carries genes that code for inducible nitric oxide synthase (iNOS), a protein that controls cell damage in blood vessels. In the current study, the inos reduced restenosis by 56 percent in the carotid arteries of treated rats, as compared with control animals. Although this particular study used ade...

Who is the arch-criminal in the development of hepatopulmonary syndrome?

...OS, HO-1 and increased number of capillaries, which demonstrated that eNOS, inos and HO-1 were involved in increased NO and CO production in the lung. The elevated NO resulted preferably from inos of pulmonary macrophages and, to a lesser extent, from eNOS in the lung of ...

iNOS expression may links chronic biliary inflammation to malignant transformation

.... Kitasato and colleagues investigated the role of inos activation, NO generation, and DNA damage as the l...es was completely suppressed by the addition of an inos inhibitor. The expression of inos mRNA in the gallbladder epithelial cells was clear...

Research Shows Carbon Monoxide Prevents Inflammations

...to limit tissue inflammation and injury induced by inos and nitric oxide during transplant rejection. Thei...ides critical protection against the OB induced by inos expression. It’s a balancing mechanism. When Hmox expression goes up, it reduces inos expression and suppresses a key-signaling pathway ...

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iNOS in Medical Technology

In Blood Vessel Stents, Innovative Materials Allow Better Control, Delivery of Gene Therapy

...or carries genes that code for inducible nitric oxide synthase (iNOS), a protein that controls cell damage in blood vessels. In the current study, the inos reduced restenosis by 56 percent in the carotid arteries of treated rats, as compared with control animals. Although this particular study used ad...

Senesco Expands on Recently Announced Preclinical Pancreatic Islet Data

...ce of pro-inflammatory cytokines. Additionally, the treated cells exhibited inos (inducible nitric oxide synthase) protein control, which is another indicator that the treated cells responded positively to inflammatory stress. inos regulates nitric oxide production, which is important for the immune respon...

Reata's Synthetic Triterpenoids Profiled in Nature Reviews Cancer

...wing: -- How the drugs were optimized to inhibit the de novo synthesis of inos and COX2 in normal mouse macrophages. inos and COX2 have essential roles in the initiation of inflammation. -- An ex...
iNOS in Medical Dictionary

Amebic liver abscess

...Clin North Am 2000; ... Innate Immunity to Amebic Liver Abscess Is Dependent on Gamma ... Susceptibility of IFN-γ receptor knockout mice and inos knockout mice to amebic liver abscess ... Liver abscess . From Wikipedia, the free encyclopedia (Redirected from Liver abscess , amebi...

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iNOS in Biological Dictionary

Vessel cell

...rough 14 liters total volume ... NO mediates mural cell recruitment and vessel morphogenesis in murine melanomas ... Host cell eNOS but not inos contributes to angiogenesis and vessel morphogenesis ... The Hox gene abdominal-A specifies heart cell fate in the Drosophila dorsal v...
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