Glucose Causes Death of Brain Cells in Rodents Following Hypoglycemic Coma
It was thought that hypoglycemic
coma causes brain damage. On the contrary brain damage occurs only when glucose is given to treat the coma//, as discovered by researchers from San Francisco VA Medical Center, during a study on rodents.
The study results may have implications on the treatment ...
New HIV Study Shows That Large Numbers of Women and People of Color Can Be Successfully Enrolled In U.S. HIV Clinical Studies
...and increased bleeding in hemophiliacs have been reported in patients receiving protease inhibitors. Initiation or dose adjustments of insulin or oral hypoglycemic
agents may be required. A causal relationship between protease inhibitors and these events has not been established.
Fat Redistribution: Redis...
Low Blood Sugar in Hospital Tied to Higher Death Risk for Diabetics
...ed in nearly 8 percent of the patients, and that each additional day with a hypoglycemic
episode was associated with an 85 percent increase in the risk of death whi...e researchers weren't able to do a comprehensive analysis to determine if a hypoglycemic
episode that occurred for an obvious reason -- such as a late meal in someo...
Novo Nordisk Warns Customers About Stolen Insulin
Hypoglycemia is the most common adverse effect of all insulin therapies, including Levemir (R) . As with other insulins, the timing of hypoglycemic
events may differ among various insulin preparations. Glucose monitoring is recommended for all patients with diabetes. Levemir (R) is not to be us...
LSUHSC researchers first to document early signs for diabetes in kids as young as 7
... LSUHSC Pediatrics fellow who is a member of Dr. Sothern's research team, is presenting results of the first study to examine why some children become hypoglycemic
(low blood sugar) during insulin sensitivity testing. She will report that children who are lean and have less fat in their skeletal muscle are more l...
Glucose metabolism and recidivism of severe violent crimes in alcohol intoxications
...he variation in the recidivistic offending and so clearly better than other variables in the international violence research.
Possibly by means of hypoglycemic
states the new violent crimes happen among these persons in alcohol intoxications when they have very low glycogen stores in the liver. The low activi...
Photo: Levemir(R) Once-Daily Substantially Lowered Average Blood Sugar Levels of Patients with Type 2 Diabetes in TITRATE(R) Study
...e substantial A1C reductions."
Rates of minor hypoglycemic
events were low and comparable between the two tre...et treatment groups, respectively). A single major hypoglycemic
event (requiring third party assistance) was repor... Levemir(R). As with other insulins, the timing of hypoglycemic
events may differ among various insulin preparatio...
Four legendary LA BioMed physician-researchers honored
...lowed him to remain broadly interested in all aspects of pediatric endocrinology and reproductive endocrinology in health and disease with emphasis on hypoglycemic
syndromes and diabetes mellitus with recent focus on neonatal diabetes and the Mody Syndromes. He has had continuous funding from the National Institu...
The Traveling Nut: Researchers From Around the World Explore the Impact of Almonds on the Body
...ave for our diets and health.
Study at a Glance:
Subjects: 120 Non-insulin dependent subjects with diabetes mellitus treated with oral hypoglycemic
Methods: In the three-month parallel study subjects were randomized to receive one of the three treatment groups: 1) Full Dose Nut Diet...
New Research Reveals Need for Doctors to Know About Medical Tattoos
...ification purposes in an emergency situation, especially for patients with diabetes, when a patient may be incapacitated - particularly in the case of hypoglycemic
coma. However, it also poses some health concerns - ones that the study's primary author, Saleh Aldasouqi, MD, FACE, feels the medical community may ...
hypoglycemic in Medical Technology
MacroGenics and Lilly Achieve Targeted Patient Enrollment in PROTEGE, a Global Phase 2/3 Clinical Trial of Teplizumab in Type 1 Diabetes
...ile trying to balance insulin doses with their food intake and daily activities, people with this form of diabetes must always be prepared for serious hypoglycemic
(low blood sugar) and hyperglycemic (high blood sugar) reactions, both of which impact quality of life and can be life threatening. This balance is es...
The Lancet Publishes Direct Comparison Study Between Liraglutide and Exenatide
...a was the most commonly reported adverse event with both treatments but the study results showed that there was less persistent nausea and fewer minor hypoglycemic
events with liraglutide compared to exenatide.
The most common adverse events reported in both groups were diarrhea, indigestion, nausea, common...
Lilly Announces Positive Phase II Data on Investigational Medicine for Patients with Type 2 Diabetes
...icantly different from placebo, but no significant differences between the doses were seen. LY2189265 was generally well-tolerated. The incidence of hypoglycemic
episodes was not significantly different between the placebo and the treatment groups. The most frequently observed treatment-related adverse events ...
Long-Term Study Evaluates Boosted PREZISTA(R) Vs. Lopinavir/Ritonavir as Part of HIV Combination Therapy in Treatment-Naive Adults
...and increased bleeding in hemophiliacs have been reported in
patients receiving protease inhibitors. Initiation or dose adjustments of
insulin or oral hypoglycemic
agents may be required. A causal relationship
between protease inhibitors and these events has not been established.
Redistribution and/or accumulat...
Data from One-Year Liraglutide Phase 3 Study Published Online in The Lancet
...45+/-4.37 kg occurred with
liraglutide 1.2 mg and 1.8 mg, respectively, versus a weight gain of
1.12+/-4.24 kg with glimepiride.
There were no major hypoglycemic
episodes reported during the study.
The rate of minor hypoglycemia was statistically significantly lower in
both liraglutide dose groups compared with...
MannKind Reports Positive Data from a Phase 3 Clinical Study of Technosphere Insulin in Type 1 Diabetes
...s reaching pre-defined A1C goals * Superior fasting blood glucose levels * Better early post-prandial glucose control * Fewer patients experiencing hypoglycemic
events * Weight loss versus weight gain * No adverse effects on pulmonary function
Dr. Peter Richardson, MannKind's Chief Scientific Officer, comm...
Modified Insulin Most Effective For Controlling Post-Meal Blood Sugar Levels
insulin preparations in terms of the frequency of hypoglycemia reported.
-- Pre-mixed insulin analogues are associated with a higher frequency
events than oral antidiabetic (non-insulin) agents are.
The report, Comparative Effectiveness, Safety and Indications of
Pre-mixed Insulin Analogues...
Sanofi Aventis: People With Type 2 Diabetes Treated With LANTUS(R) and APIDRA(R) Achieved Greater Reductions in A1C Than Those Treated With Pre-mixed Insulin
...ANTUS(R) and APIDRA(R) therapy
also tended to experience fewer on-treatment hypoglycemic
compared to pre-mixed insulin, with 14.0 and 18.5 events/patien...sed insulin with a mean daily dose of 71IU, about 70%
of patients used oral hypoglycemic
agent(s) and 29% had chart records for
hypoglycemia. Mean follow-up time wa...
Novo Nordisk New Data From a Phase 3 Study Confirms Clinical Benefits of Once-Daily Liraglutide in the Management of Type 2 Diabetes
... -2.6 -2.7* -0.8
% reporting minor hypoglycemic
9 8 5 events/subject/year 0...dial glucose
Safety and tolerability of liraglutide
There were no major hypoglycemic
episodes reported during the study.
The rate of minor hypoglycemia (<3.1 mm...
Tolerx Initiates Dosing of Otelixizumab, a Novel Type 1 Diabetes Agent, in DEFEND, a Phase 3 Clinical Trial
... a surrogate measure of beta cell function. Maintenance of
beta cell function has been associated with improved glycemic control
(HbA1c levels), fewer hypoglycemic
events, and a reduction in long-term
disease complications in established type 1 diabetics in the Diabetes
Control and Complications Trial (DCCT).
hypoglycemic in Medical Products
GlucoWatch G2™ Biographer
Features:... Provides automatic noninvasive readings as frequently as every 10 minutes for up to 13 hours
Identifies almost 6 times more hypoglycemic
events than twice daily finger-stick blood glucose testing
Detects 13 times more hyperglycemic events than twice daily finger-stick blood glucose t...
hypoglycemic in Medical Dictionary
...e, bathing, medications... insulin shock therapy ( ′insələn ¦shäk ′therəpē ) ( medicine ) Administration of large doses of insulin to induce hypoglycemic
comas, followed More about Hypoglycemia: Causes and symptoms Diagnosis Treatment Alternative ... Hypoglycemia (also known as a hypo, insulin sh...
hypoglycemic in Biological News
Glucose triggers brain cell death in rats after hypoglycemic coma
Brain damage that was thought to be caused by hypoglycemic
coma actually occurs when glucose is administered to treat the coma, according to a study in rodents led by researchers at the San Francisco VA Medical Center.
The results are surprising, say the authors, and may be of clinical significa...
Study shows CGM devices also benefit people with type 1 diabetes
...oup had a decrease in HbA1c of more than 0.3% without experiencing a severe hypoglycemic
event (28% versus 5%).
Encouragingly, similar beneficial results were s... is often followed by a decline in glycemic control due to fears of further hypoglycemic
episodes. Hypoglycemia remains the major limiting factor for people with t...
HIV-1 protease inhibitor induced oxidative stress in pancreatic B-cells: thymoquinone protection
...ion by pancreatic beta-cells and they further investigated the therapeutic strategies to ameliorate the insulin dysregulation at this level. Since the hypoglycemic
effects of Nigella sativa oil have been investigated in the past, the investigators postulated that nelfinavir induced oxidative stress may be amelior...
JDRF to provide $1M in funding to SmartCells, Inc.
...iabetes. Our formulation is designed to address the most critical issue in diabetes treatment achieving tight glucose control without inducing severe hypoglycemic
episodes. To accomplish this, patients will only have to inject SmartInsulin once a day using the same needles currently used for conventional insulin...
Hormone helps mice 'hibernate,' survive starvation
...some proliferator-activated receptor alpha, or PPAR-alpha, which is known to control the use of fat as energy. Starving mice without PPAR-alpha become hypoglycemic
and quickly die.
In analyzing the molecular impact of PPAR-alpha in mice, the researchers found that it stimulates production of FGF21, a member ...
hypoglycemic in Biological Technology
New Data From Head-to-Head Phase 3 Trial Demonstrate That Liraglutide is More Effective Than Exenatide in Treatment of Type 2 Diabetes
Change FPG (fasting plasma glucose) mmol/L from baseline -1.61* -0.60
events/subject/year 1.9* 2.6
Once-daily liraglutide is the first hu...
Insulet Reports Second Quarter 2008 Results
...odel-predictive, closed-loop control algorithm. Dr. Cobelli reported
that the system had demonstrated excellent overnight blood glucose control
and no hypoglycemic
-- At the 2008 Annual Meeting of the American Association of Diabetes
Educators earlier this month, the Endocrine Group and the Albany Colle...
Biodel Inc. Reports Second Quarter Fiscal Year 2008 Financial Results
...og(R), coupled with successful Phase III
data, will lead physicians to prescribe VIAject(TM) to both new patients
and patients suffering from frequent hypoglycemic
Three Months Ended March 31, 2008
Biodel reported no revenue during the three months ended March 31, 2008
and March 31, 2007.
Anesiva Grants Specific-Use License of Its Needle-Free Drug Delivery Technology to Particle Therapeutics for Diabetes Drug
...hief executive officer of Anesiva.
"We intend to seek other opportunities for licensing this important
platform technology." "Patients experiencing a hypoglycemic
condition may lose consciousness,
and if not treated quickly, can suffer short and long-term cerebral
damage," remarked Fred Cornhill, Director of Par...
hypoglycemic in Biological Definition
...xercise and foot care.
The most important is the hypoglycemic
treatment with either oral hypoglycemics and/or in...ay be too much if less food is consumed causing a hypoglycemic
reaction if not intelligently adjusted. In additi...ion, the onset and duration of the effects of oral hypoglycemic
agents vary from type to type and from patient to ...
...enaline ), which increase blood glucose
and one hypoglycemic
hormone (insulin), which decreases blood glucose
...ing insulin or other pharmacologic treatment. Such hypoglycemic
episodes vary greatly between persons and from tim...oglycemia or, in cases producing unconsciousness, hypoglycemic
coma (formerly termed insulin shock from the mos...
hypoglycemic in Biological Dictionary
... ... What other drugs will affect glucagon ? Where can I get more information? ... How to Administer a Glucagon Injection. When a diabetic has a hypoglycemic
episode (a sudden drop in blood sugar), time is of the essence. If the person is ... ...
.... Medical information about Diabetes Mellitus, Type 2, Type 1, and Metabolic Disorders treatment and medications. ... When glucose levels fall to hypoglycemic
... glucose glossary includes a list of glucose related medical definitions and related ... and medical definitions of terms that appear in the...