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Symbiotic bacteria protect hunting wasps from fungal infestation

Researchers have discovered a fascinating symbiotic relationship between a wasp species and a newly discovered bacterial species ?a relationship that potentially sheds light on how bacteria can be successfully utilized by higher organisms in defensive mechanisms against other microbes. In the new work, researchers show that a solitary ground-nesting wasp, the European beewolf, harbors Streptomyce...

U. Iowa researchers improve Huntington's disease symptoms in mice

Researchers at the University of Iowa Roy J. and Lucille A. Carver College of Medicine have taken another step toward a potential treatment for Huntington's disease (HD). Using an approach called RNA interference (RNAi), the scientists reduced levels of the disease-causing HD protein in mice and significantly improved the movement and neurological abnormalities normally associated with the diseas...

New insights into how Huntington's disease attacks the brain

Scientific theory holds that Huntington's disease (HD) is caused by a mutant protein that arises within brain cells and kills them, triggering the genetic neurological disorder. Now a new UCLA Neuropsychiatric Institute study reveals the first strong evidence that the mutant protein also elicits toxic interactions from neighboring cells to provoke the fatal brain disorder. The May 5 edition of Ne...

Huntington's cure in flies lays groundwork for broader treatment approaches

Boosting levels of two critical proteins that normally shut down during Huntington's disease, researchers at the University of Wisconsin-Madison and the Cold Spring Harbor Laboratory have cured fruit flies of the genetic, neurodegenerative condition. The study results,...

Molecular trigger for Huntington's disease found

Researchers have discovered a key regulatory molecule whose overactivation by the abnormal protein produced in Huntington's disease (HD) causes the central pathologies of the disease. The abnormal HD protein activates the regulatory protein called p53, which in turn switches on a host of other genes. This abnormal gene activation damages the cells' power plants, called the mitochondria, and kills...

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Job hunting the Air Google way

First, every half century or so, advertisers accidentally tumble onto a new idea that makes the entire industr...

Pay attention to your alumni connections when job hunting

Though I can't s...
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Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of ‘Huntingtons’ Disase

Huntingtons disease is an inherited disease of the nervous system due to the progressive gradual deterioration of the same, initially causing symptoms such as involuntary movements and balance problems and later on leading to declination of functions of speech as well. All these days, until now, it was thought that this disease is due to a mutated form of the protein 'huntingtin' which i...

Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of Huntingtins’ Disese

Huntingtons disease is an inherited disease of the nervous system due to the progressive gradual deterioration of the same, initially causing symptoms such as involuntary movements and balance problems and later on leading to declination of functions of speech as well. All these days, until now, it was thought that this disease is due to a mutated form of the protein 'huntingtin' which i...

Effective therapy for Huntington's disease

An acid found naturally in the body can block the death of brain cells in mice who have Huntington's disease. There is no cure for Huntington's disease (HD), which is a rare degenerative brain disorder //caused by a faulty gene. But researchers at the University of Texas may be one step closer to a treatment, according to experiments on mice with HD. The mice were treated with a bile...

New info about Huntington's disease found

Scientists of UCLA have found out evidence that sheds new light on the details of how Huntington's disease// affects the brain cells of the patient. Huntington's disease is a genetic disorder that slowly destroys the ability of the person to think or move on his own. Early symptoms of the disease may be depression, mood swings, forgetfulness, and inability to concentrate or remember. I...

Research identifies trigger that sets of Huntingtons disease

Researchers have discovered the key molecule that gets over activated by the protein of the Huntingtons disease// and sets way for the condition to be expressed. Huntingtons disease is a genetic disorder that slowly destroys the ability of the person to think or move by himself. Early symptoms of the disease may be depression, mood swings, forgetfulness, and inability to concentrate or r...

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Huntington Disease

Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...
Company:ARUP Laboratories
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Clinical Trial Results Suggest Long-Term Treatment Benefit of Tetrabenazine for Chorea Associated with Huntington's Disease

BOSTON--(BUSINESS WIRE)--May 3, 2007 - New data show theinvestigational drug tetrabenazine maintained reduction of choreaassociated with Huntington's disease (HD) up to 80 weeks in thosepatients who successfully completed treatment in a 13-week trial.These data suggest that tetrabenazine can be used successfully tosustain reduced chorea burden in long-term use. "These findings demonstrate...

Amarin Reports Top-Line Results of two Phase III Studies of Miraxion in Huntington's Disease

Conference Call Begins Today at 11:00 a.m. Eastern Time LONDON, April 24, 2007 /PRNewswire-FirstCall/ -- AmarinCorporation plc ("Amarin" or the "Company") today announcestop-line results from its two Phase III clinical trials of Miraxionto treat Huntington's disease (HD). The Company conducted two PhaseIII double-blind, placebo-controlled studies in which HD patientswere randomized to rec...
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