hijacks

Prestigious fellowship for young Nottingham researcher

...the disease becomes more chronic it can lead to serious scarring of the liver (cirrhosis) and even cancer. Dr Jopling's research looking at how HCV hijacks miR122 to help in its attack on the liver has been recognised by the BBSRC because of the important role it plays in developing our understanding of g...

Cold Spring Harbor scientists reveal a protein's role in enabling AIDS virus to reproduce

...oat and immediately proceed to integrate its newly converted DNA -- containing 9 genes -- into the host cells DNA. In this way the virion effectively hijacks the cell and reproduces itself whenever the cell reproduces. Dr. Skowronski has devoted years to the study of various molecular factors -- think ...

Iowa State chemists track how drug changes, blocks flu virus

...low through the channel into the virus and raise its acidity. That triggers the release of the virus genetic material into the healthy cell. The virus hijacks the healthy cells resources and uses them to reproduce and spread the virus. If the M2 proton channel is blocked, the process doesnt work and a v...

Viral Enzyme Recruited in Fight Against Ear Infection

...a special enzyme to destroy the cell walls. Phages infect bacteria in a way that is similar to how viruses infect animal cells. Once inside, the virus hijacks the cell’s biochemical machinery and forces it to make many copies of the virus. After the new crop of viruses is made, a viral enzyme breaks apart th...

hijacks in Medical Technology

DNA Therapeutics Reports a Novel Mechanism of Action and a Biomarker of its Lead Molecule Dbait That Open an Innovative Pathway-Targeting in Molecular Cancer Therapy

... Dutreix who conducted this study said "this additional mechanism of antitumoral action of Dbait molecules confirms that the use of Dbait which baits, hijacks the enzyme complexes that repair DSBs and disorganizes DSB repair system, is a novel and attractive pathway-targeting approach in molecular cancer the...

hijacks in Biological News

Herpes virus hijacks DNA repair process

June 13, 2007 -- Scientists probing the details of viral infection have discovered an intriguing surprise: in mice, herpes viruses hijack their host cells' tools for fixing DNA damage and use those tools to enhance their own reproduction. The DNA damage response normally fixes DNA errors caused ...

Research details how a virus hijacks cell signals to cause infection

A common virus that causes meningitis and heart inflammation takes a "back door" approach to evade natural barriers, then exploits biological signals to infect human cells. Broadening knowledge of how viruses cause infection, a new study describes elaborate methods that the virus has evolved to byp...

Scientists reveal how deadly toxin hijacks cells

Scientists have pinpointed exactly how botulinum neurotoxin A - a potential agent of biological warfare and one of the most lethal toxins known to man - is able to sneak into cells. The finding is crucial for the development of new treatments against botulism, a paralytic illness caused by the t...

Evolutionary biologist will study HIV with grant from AIDS research foundation

...to discover new targets for drugs. When HIV infiltrates cells, the virus hijacks its host's genetic machinery to produce proteins and ultimately replicate itself. It has been recently found that the retrovirus hijacks about 1,000 human genes. "The big challenge now is to find which of thes...

Tracking the molecular pathway to mixed-lineage leukemia

...ces them into a hyperactive state, with disastrous consequences. "The MLL-AF4 fusion protein is somehow targeted to a set of genes that essentially hijacks the blood stem cell machinery and makes that cell become cancerous, basically a younger-looking cell that is dividing much more than it should," says ...

Class of antibiotics can enhance gene-silencing tool

... Medicine for their discovery that short pieces of RNA, when introduced into cells, can silence a stretch of genetic code. Artificially introduced RNA hijacks machinery inside the cell called the RNA-induced silencing complex or RISC. To probe how RISC works, Jin and his co-workers inserted a gene for a f...

Legionnaire's bacterial proteins work together to survive

...ders. What makes this pathogen special is that it can control transport of the vacuole formed after macrophages ingest the bacterium, Roy said. It hijacks the vacuole and directs it to be transported to a nutrient-rich organelle called the endoplasmic reticulum, where the bacteria replicate in high numbe...

U of S Vaccine and Infectious Disease Organization team discovers key step in flu virus replication

...velop new influenza treatments and prevent the disease, as well as add to global pandemic preparedness research." To survive, the influenza virus hijacks the host animal or human's cellular machinery and forces it to make more copies of the virus. The researchers believe that the cellular events involve...

HIV infection requires an accomplice: B cells with special protein direct HIV to T cells

...roved HIV drug regimens and most of those being tested in clinical trials focus on T cells of the immune system, where HIV replicates and thrives. HIV hijacks T cells by binding to a cell membrane molecule called CD4 and to either or both of two other receptors, from which the two strains of HIV, X4 and C5, ...

Scientists a step closer to protecting world's most important crop

... at the University of Exeter have shown for the first time, in a paper in the prestigious journal Nature, how the world's most destructive rice-killer hijacks its plant prey. In order to infect plants the fungus has to inject its proteins into the plant's own cells where they overcome the plant's defences...

hijacks in Biological Technology

Taming the anthrax threat

... pass unrecognized inside macrophages, the primary immune cells able to kill most bacteria. Somehow the bacterium avoids being killed and actually hijacks these phagocytes (microbe-killing cells), Bergman says. New drugs, he says, should target the bug during the brief window of vulnerability when the ba...

Taming the anthrax threat

... pass unrecognized inside macrophages, the primary immune cells able to kill most bacteria. Somehow the bacterium avoids being killed and actually hijacks these phagocytes (microbe-killing cells), Bergman says. New drugs, he says, should target the bug during the brief window of vulnerability when the ba...