Monogram Announces 2008 Third Quarter Financial Results

...l protein assays, the HER1:HER1 homodimer assay and the activated HER1:HER2 heterodimer assay, at the 20th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Geneva, Switzerland. Data on the HER2:HER3 heterodimer assay and the HER3:PI3K assay will be presented at the AACR "Targeting the ...

Use of FlashPlate Technology for In Vitro Measurement of 125I-Labeled TGF-1 Binding on Chimeric Extracellular Domain of Type II Transforming Growth Factor Receptor

...TRI and TRII (470 + 32 pM). In these experiments, the affinity of the chimeric soluble receptor for TGF-1 was threefold lower than the affinity of the heterodimer receptor complex (TRI and TRII) on the cell surface, but was very similar to that of TRII when expressed alone in the Cos-1 cell line. One s...

Purification of Phosphoinositide 3-Kinase With UNO Columns

... Phosphoinositide 3-kinase has been purified to homogeneity from rat liver and bovine thymus. The enzyme from rat liver is a heterodimer of 110 and 85 kDa proteins.Two forms of the 110 kDa protein exist, and have similar but not identical amino acid sequenc...

Apoptosis detection by annexin V and active caspase-3 with the Agilent 2100 bioanalyzer

...g apoptosis by self-proteolysis and/or cleavage by another protease8. Active caspase-3, a marker for cells undergoing apoptosis, consists of a heterodimer of 17 and 12 kDa subunits which is derived from the 32 kDa proenzyme9. A convenient and broadly accepted method to study the activity of cas...

pFB-ERV: Retroviral Delivery of the Ecdysone Receptor Proteins

...d histone deacetylase, and is, thus, tightly repressed until ligand binding, at which time high-level transcriptional activation occurs (i.e., the heterodimer is converted from a tight repressor to a trans-activator). Using the Complete Control plasmid-based system, induction ratios of greater than 1,000...

Versatile Vectors for Ponasterone A- Inducible Control of Gene Expression in Mammalian Cells

... System Description The ecdysone receptor (EcR) is a member of the RXR heterodimer family of nuclear receptors. In mammalian cells, the EcR heterodimerizes ...rs, which require perfect inverted half-sites, or by natural RXR heterodimer family receptors, which require single nucleotide spacing betwee...

heterodimer in Biological Products

Anti-S-100 protein, ab heterodimer Monoclonal Antibody, Unconjugated from HyTest Ltd.

Description: High affinity antibody reacting with S-100 ab heterodimer. Could be used for Western blotting application and immunoassay....
Company:HyTest Ltd.

Anti-Factor XIIIa Ab-2 Polyclonal Antibody, Unconjugated from Lab Vision

Description:...is composed of two subunits. Factor XIII-A is the catalytic subunit and is a dimmer of M.W. 160kDa. Factor XIII is present in plasma as an Alpha2Beta2 heterodimer (M.W. 320kDa); whereas in platelets, only the Alpha2 unit exists. Factor XIIIa is a dermal dendrocyte marker and shows variable reaction with these ty...
Company:Lab Vision

PPase-2A from Promega

Description:... Protein Phosphatase-2A (PPase-2A) is a serine/threonine phosphatase isolated from human red blood cells. It is isolated as the heterodimer of 60kDa (A) and 36kDa (C) subunits. It has the ability to dephosphorylate the a-subunit of phosphorylase kinase. With its 3638kDa catalytic subunit, ...
Company:Promega

heterodimer in Biological Definition

Dimer

...fructose molecule. In biology , a dimer is a protein complex made up of two subunits. In a homodimer the two subunits are identical, and in a heterodimer they differ (though they are often still very similar in structure). The subunits do not need to be covalently linked, and usually aren't. See a...

heterodimer in Biological Dictionary

Tubulin

... the major building block of microtubules. ... See below for alpha Tubulin antibody images, references, products ... Tubulin is composed of a heterodimer of two closely related 55 kDa proteins ... Glycerol can stimulate tubulin polymerization. ... Tubulin protein has been purified from bovine...

MutS

...Gene: MSH4 mutS homolog 4 (E. ... Human MutS homologue MSH4 physically interacts with von ... hMSH5: a human MutS homologue that forms a novel heterodimer ... Multicopy plasmids carrying mutS alleles that are dominant negative for MMR were ... MutS , on the other hand, binds to most mismatched ...

Microtubules

...seen in a bundle in this negatively stained preparation. ... a,b-Tubulin heterodimer & microtubule structure. Centriole & centrosome ... A n a,b-tubulin heterodimer is the basic structural unit of microtubules . ... Spiral arranged mic...

Ecdysone

...receptor found in arthropods, where it controls development and contributes to other processes such as reproduction. The receptor is a non-covalent heterodimer of two proteins, the EcR protein and ultraspiracle protein (USP).... Thus, ecdysone released by the prothoracic glands appeared to directly i...