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halted in Medical News

Cancer Drug Trials Often Halted Early

Without thorough review, Italian study says the trend poses risks to patients FRIDAY, April 11 (HealthDay News) -- An increasing number of clinical trials for new cancer treatments are being halted before the risks and benefits have been fully evaluated, say Italian researchers, who w...

Viagra Trial for Sickle Cell Lung Problems Halted

Safety concern from side effects prompts action by U.S. government TUESDAY, July 28 (HealthDay News) -- The first clinical trial of a treatment for pulmonary hypertension in adults with sickle cell anemia has been stopped because of severe side effects in some participants. The tria...

Wrong-Sided Brain Surgery Trial Halted

OVER POSSIBLE JUROR MISCONDUCT LITTLE ROCK, Ark., May 2 /PRNewswire/ -- (The following is from the Duncan Firm) --Attorneys for parents suing Arkansas Children's Hospital over a wrong sided brain surgery abruptly halted the trial today citing possible juror misconduct. "...

The Production and Marketing of IBS Drug Halted by the Chinese Government

The Chinese Food and Drug administration has put a halt to the production and marketing of Novratis AGs Zelnorm Drug, for irritable bowel syndrome, as the risk associated with it outweighs the benefits. The patients are asked to stop taking the medication. The Chinese Drug watchdog posted ...

Anti-retroviral drug conserving trial halted

The National Institute of Health has asked to stop SMART trial (Strategies for Management of Anti-retroviral Therapy) which is a trial on AIDS patients who are undergoing Anti-retroviral //therapy which recommends patients to have the drugs only when it is required contrasting to routine therapy wh...

STAAR Surgical Generates Cash From Operations During Second Quarter

... in both our Visian ICL and IOL lines for the second half of the year," Mr. Caldwell continued. "The FDA's decision to remove the integrity hold that halted scientific review of our Visian Toric ICL means that review of our PMA supplement has resumed. In addition, we are making progress in the regulatory ...

National Leaders Examine Sex and Responsibility in New Book

...en in ten pregnancies are described by women themselves as unplanned. Progress in reducing unplanned pregnancy among women of all ages has essentially halted and--although teen pregnancy and birth rates have declined dramatically since the early 1990s--the teen birth rate increased 5% between 2005 and 2007,...

Drug Found Ineffective Against Lung Disease

...n gamma-1b (Ifn-g1b) does not improve survival in people with a fatal lung disease called idiopathic pulmonary fibrosis, according to a study that was halted early after no benefit to participants was found. Previous research had suggested that Ifn-g1b might benefit people with idiopathic pulmonary fibro...

Herb May Offer Hope for Autoimmune Diseases

...g immune system THURSDAY, June 4 (HealthDay News) -- A compound derived from hydrangea root, an herb used in traditional Chinese medicine, halted the progression of an autoimmune disorder in laboratory mice and human cells, new research shows. What makes the compound, halofuginone, so promisi...

Overweight male teens with normal blood pressures showing signs of heart damage

... illustrated the potential benefit of reducing aldosterone levels even in people already suffering from heart failure. The study of 1,663 patients was halted early because of significantly reduced death rates in those taking the aldosterone-lowering, anti-hypertensive spironolactone. Patients on other anti-...
halted in Medical Technology

Neurointerventionists Expand Research to Quality of Life in Aneurysm Patients Following Minimally Invasive Coiling Treatment

...N, Fla., July 28 /PRNewswire-USNewswire/ -- Since the groundbreaking 2002 ISAT International Subarachnoid Aneurysm Trial (ISAT) - which ultimately was halted due to overwhelming evidence that minimally invasive coiling (an endovascular therapy) was, on average, superior to traditional surgical clipping in t...

New Therapy Enlists Immune System to Boost Cure Rate in a Childhood Cancer

... led to a greater cure rate -- the first substantial increase in cure rate for neuroblastoma for more than a decade," said Maris. The researchers halted the trial earlier than expected after early results showed the benefits of immunotherapy. "This experimental immunotherapy is poised to become part of...

Mayo Clinic Study Finds Younger Men With Erectile Dysfunction at Double Risk of Heart Disease

...of Mayo Clinic Proceedings. The results "raise the possibility of a 'window of curability,' in which progression of cardiac disease might be slowed or halted by medical intervention," writes Dr. Miner, who practices at the Men's Health Center, Miriam Hospital, Providence, R.I. Erectile dysfunction is ...

RAD001 Phase II Trial Results Positive in Patients with Advanced Gastric Cancer After Failure of One or More Prior Treatments

... - After eight weeks of treatment, RAD001 halted tumor growth in 55% of advanced gastric cancer patients previously treated ...day show RAD001 (also known as everolimus; proposed brand name Afinitor(R)) halted tumor growth in 55% of patients with advanced gastric cancer, a condition f...

New Study First to Confirm Sandostatin LAR(R) Depot Controls Tumor Growth in Patients With Rare Gastrointestinal Tumors

... reduction in risk of disease progression compared to patients taking placebo ( P =0.000072). This reduction is based on findings that Sandostatin LAR halted tumor growth in 69% of patients, compared with 39% of patients receiving placebo. Patients who took Sandostatin LAR had no tumor progression for a med...

RAD001 Shows Potential to Reverse Resistance to Herceptin(R)* in Metastatic Breast Cancer Patients, Leading to Phase III Trial

...the combination of RAD001 with Herceptin and weekly Taxol(R) (paclitaxel)** halted tumor growth in 77% of patients with HER2-positive metastatic breast cancer...st cancer. In the study, RAD001 in combination with Herceptin and Navelbine halted tumor growth in 62% of patients. "Data presented at this meeting af...

Sunesis Pharmaceuticals Announces Presentation of Voreloxin Clinical Data in Patients with Acute Myeloid Leukemia at the 50th Annual Meeting of the American Society of Hematology

...sis' need for additional funding, the risk that Sunesis' development activities for voreloxin, including enrollment and reporting of results, could be halted significantly or delayed for various reasons; the risk that Sunesis' clinical trials for voreloxin may not demonstrate safety or efficacy or lead to r...

Sunesis Pharmaceuticals Presents Clinical Trial Data of Voreloxin in Patients with Acute Myeloid Leukemia and Ovarian Cancer at the Chemotherapy Foundation Symposium

...sis' need for additional funding, the risk that Sunesis' development activities for voreloxin, including enrollment and reporting of results, could be halted significantly or delayed for various reasons; the risk that Sunesis' clinical trials for voreloxin may not demonstrate safety or efficacy or lead to r...

In Vivo Data on Taligen Therapeutics' Pipeline Candidates Presented at the XXII International Complement Workshop

...s In vivo studies in models for several complement-mediated diseases showed that targeted inhibition of the alternative complement pathway slowed or halted disease progression in these models. Sekine et al. investigated whether TT30 prevented progression of renal disease in a lupus nephritis murine model ...

SARcode and Sunesis Announce Start of Phase 1 Clinical Trial in Ocular Inflammatory Diseases

...atements as a result of these risks and uncertainties, which include, without limitation, the risk that SARcode's drug development activities could be halted or delayed significantly for various reasons and the risk that Sunesis may not receive any future payments from SARcode under the license agreement. T...
halted in Medical Products

LM-380

Features:... Cordless operation. Replacement of light bulb not required. Accepts larger diameter lenses. Power is automatically turn off whenever operation is halted over three minutes. Prism compensator is optionally available....
Company:NIDEK, Inc.
halted in Medical Definition

Anthrax Vaccine Immunization Program

...taken to correct deficiencies on March 11, 1997. [4] In June 2001, the DOD halted vaccination due to non-FDA approved changes in BioPort's manufacturing proc...Injunction on Summary Judgment, Oct 27, 2004 ^ "Anthrax Vaccinations halted Again" United Press International, October 28, 2004. ^ "Troops divi...
halted in Medical Dictionary

Hiv infection

... has sex ... The mean interval between infection with HIV and the onset of AIDS exceeds ... Transmission of HIV infection can be slowed or halted by reducing or eliminating ... Human immunodeficiency virus infection . Causes ... related to HIV infection include: Diarrhea. Fatigue ... ...
halted in Biological News

Steep oxygen decline halted first land colonization by Earth's sea creatures

Vertebrate creatures first began moving from the world's oceans to land about 415 million years ago, then all but disappeared by 360 million years ago. The fossil record contains few examples of animals with backbones for the next 15 million years, and then suddenly vertebrates show up again, this ...

First genetically-engineered malaria vaccine to enter human trials

...y genes in the Plasmodium falciparum parasite which causes the form of malaria most deadly to humans. By removing the genes the malaria parasite is halted during its liver infection phase, preventing it from spreading to the blood stream where it can cause severe disease and death. Their success in gen...

Muscle atrophy through thick but not thin

...ave to wait for caspases or calpains to "pre-digest" the myofibril components. The work also bears on the practical question of whether atrophy can be halted or reversed with drugs. "It argues against MuRF1 inhibitors" for this purpose, Goldberg says, because the enzyme is responsible for degrading only som...

New simulation shows consequences of a world without Earth's natural sunscreen

...world we should be glad we avoided." The real world of CFC regulation has been somewhat kinder. Production of ozone-depleting substances was mostly halted about 15 years ago, though their abundance is only beginning to decline because the chemicals can reside in the atmosphere for 50 to 100 years. The pe...

Researchers identify promising gene target for neuroblastoma therapy

...-blocking molecule into batches of test cells whose ALK receptors harbor each of the newly discovered mutations. The small molecule inhibitor, TAE684, halted proliferation and brought on the death of cells with the most common mutation, designated F1174L, as well as cells with another of the mutations. W...

Potatoes may hold key to Alzheimer's treatment

...rove cognitive function, possibly by promoting the destruction of amyloid plaques. Some early human trials have likewise been promising, but had to be halted due to the risk of autoimmune encephalitis. One way to make Alzheimer's vaccinations safer would be to use a closely-related, but not human, protei...

Leatherback turtles' newly discovered migration route may be roadmap to salvation

...a (Drexel University), the Leatherback Trust, and staff and volunteers from the Costa Rican Ministry of Environment and Energy, that practice has been halted locally. People who once collected eggs are now paid to protect them and tourists have been coming to see the turtles. "Turtle tourism has emerged as ...

Pathway found that lets mosquitoes fatten up, slow down for winter

...re prepared to deposit mature eggs, the scientists used a technique to disrupt the insulin receptor gene from completing its function. This disruption halted reproductive activity in the mosquitoes and caused them to enter a state resembling diapause. On the other end of the diapause spectrum, the scient...

Bear spray a viable alternative to guns for deterring bears, BYU study shows

...muscle and teeth, Smith and colleagues analyzed 20 years of bear spray incidents in Alaska, home to 150,000 bears. He found that the spray effectively halted aggressive bear behavior in 92 percent of the cases, whether that behavior was an attack or merely rummaging for food. Of all 175 people involved in t...

An Alzheimer's vaccine?

...queshas been considered a promising way to tackle the disease, but its success has been limited. In 2002, for example, the pharmaceutical company Elan halted trials of a different vaccine after 15 patients suffered swelling of the central nervous system. OMRF President Stephen Prescott, M.D., is hopeful ...
halted in Biological Technology

First genetically engineered malaria vaccine to enter human trials

...y genes in the Plasmodium falciparum parasite which causes the form of malaria most deadly to humans. By removing the genes the malaria parasite is halted during its liver infection phase, preventing it from spreading to the blood stream where it can cause severe disease and death. Their success in gen...

Sunesis Reports Financial Results for the Second Quarter 2009

... which include, without limitation, risks related to Sunesis' need for additional funding, the risk that Sunesis' drug development activities could be halted significantly or delayed for various reasons, the risk that Sunesis' clinical trials for voreloxin may not demonstrate safety or efficacy or lead to r...

Pharmasset Reports Fiscal Second Quarter 2009 Financial Results

...harmasset that is expected to be received in the quarter ending June 30, 2009; On April 20, 2009, Pharmasset announced that it had voluntarily halted its phase 3 registration studies of clevudine for the treatment of chronic hepatitis B infection; On March 31, 2009, Pharmasset announced the ...

Sunesis Pharmaceuticals Reports Fourth Quarter and Full-Year 2008 Financial Results

...sis' need for additional funding; the risk that Sunesis' development activities for voreloxin, including enrollment and reporting of results, could be halted significantly or delayed for various reasons; the risk that Sunesis' clinical trials for voreloxin may not demonstrate safety or efficacy or lead to r...

Catalyst Pharmaceutical Partners Reports Fourth Quarter and Year-End 2008 Financial Results

...der to conserve cash and to focus its development efforts on evaluating CPP-109 for the treatment of cocaine addiction, Catalyst announced that it had halted enrollment in the methamphetamine trial. Instead, the methamphetamine trial has been converted into a smaller proof-of-concept study with the 57 subje...

Neurobiological Technologies Announces Suspension of Viprinex Development

...died in a clinical trial to determine whether it was effective in improving patient outcome when given within six hours of a stroke, but the trial was halted for futility following an interim analysis. "Following a thorough review of the interim data, it was determined that there was no group of pati...

Sunesis Pharmaceuticals Provides Year-End Clinical Update on Voreloxin

...sis' need for additional funding, the risk that Sunesis' development activities for voreloxin, including enrollment and reporting of results, could be halted significantly or delayed for various reasons; the risk that Sunesis' clinical trials for voreloxin may not demonstrate safety or efficacy or lead to r...

China Medicine Announces Strong Second Quarter 2008 Results

...mes, the application for a production permit will be delayed since the Chinese government mandated that all toxic tests and experiments be temporarily halted before and during the Olympics. Therefore, further testing on rADTZ will be suspended for approximately three months. To date, the Company has been ...

Sunesis Pharmaceuticals Expands Development Leadership Team to Focus on Late-Stage Development of Voreloxin (Formerly SNS-595)

...thout limitation, the risk that Sunesis' drug development activities or those of its partners, including enrollment and reporting of results, could be halted significantly or delayed for various reasons; the risk that Sunesis' clinical trials for voreloxin or its other programs may not demonstrate safety or...

Microtest Labs Doubles Microbial Identification, Analytical Services

.... "Our ability to provide rapid identification helps our customers minimize down-time, which directly affects their bottom-line. When manufacturing is halted or a cleanroom is shut-down and awaiting test results, there is no product going out the door and that translates to an interruption in sales." The ...
halted in Biological Definition

Gene therapy

...ng cell division, uncontrolled cell division (i.e., cancer ) can occur. Gene therapy trials to treat severe combined immunodeficiency (SCID) were halted or restricted when leukemia was reported in several of the patients. Adenoviruses Adenoviruses are viruses that carry their genetic material ...
halted in Biological Dictionary

Secondary oocyte

...elopment. The germ cells produce a primordial germ cell (PGC) which becomes an... secondary Oocyte . haploid. Ootidogenesis (meiosis 2) halted in metaphase II until fertilization ... with formation of a polar body and a secondary oocyte . ... What is secondary oocyte ? Mean...

Leader sequence

...tics of operons ( in operon (genetics) ) ...the corepressor. Some operons are under attenuator control, in which transcription is initiated but is halted before the mRNA is transcribed. This introductory region of the mRNA is called the... Mennonite Offers Clinical Nurse Leader Sequence . Date: 2/...

Clone bank

...the ... When the Clone Wars erupted, Chairman San Hill brought the Banking Clan into the ... Working for the Bank during the Clone Wars, he halted several Separatist ... A Merc and an Old Bounty Hunter Join Clone Wars. From the MTV Movies Blog ... clones, clone a sheep, pc clone ... clo...
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(Date:4/24/2014)... NH, 4/24/14) Dartmouth has been awarded one of ... serve as a Lead Academic Participating Site in its ... Award recipients are a select groups of investigators charged ... fewer cooperative groups., The NCTN grant system reflects recommendations ... It streamlines operations to achieve four goals:, ...
(Date:4/24/2014)... Orleans, LA The National Science Foundation has ... Research Experiences for Undergraduates (REU) Site grant in ... the training of undergraduates from diverse social and ... the New Orleans area. The project will ... the summers of 2014-16. It will be ...
(Date:4/24/2014)... research led by a scientist at the University of ... element in the development of the nervous system may ... breast cancer., A research team, led by Dr ... Department of Biology at York, has studied how voltage-gated ... These channels are found in the membranes of excitable ...
(Date:4/23/2014)... was safe and effective in treating patients with ... , according to a new pilot study published ... online. Known as fecal microbiota transplantation, the treatment ... or a nasogastric tube. The findings suggest approaches ... available to patients. , A growing concern, ...
(Date:4/23/2014)... Moffitt Cancer Center researchers say clinical trials for ... leukemia (AML) are very promising. Patients treated with ... and daunorubicin, are showing better responses than patients ... , "Acute myeloid leukemia is an aggressive ... success, especially in older patients," explained Jeffrey Lancet, ...
Breaking Medicine News(10 mins):Health News:Dartmouth awarded lead role in NCI clinical trials network 2Health News:Dartmouth awarded lead role in NCI clinical trials network 3Health News:Breast cancer replicates brain development process 2Health News:Pilot study suggests ways to widen access to fecal transplants for C. diff infections 2Health News:Moffitt Cancer Center's phase 3 study may be game-changer for acute myeloid leukemia 2
(Date:4/23/2014)... Like a hungry diner ripping open a dinner roll, ... must tear open a hydrogen molecule. Now researchers have ... the two halves of its hydrogen feast. The view ... make the catalyst work better for alternative energy uses. ... shown precisely where the hydrogen halves end up in ...
(Date:4/23/2014)... 23 2014) A team of researchers ... (hNSCs) into the brains of nonhuman primates and ... 24 months found that the hNSCs had differentiated ... cause tumors. , The study will be published ... but is currently freely available on-line as ...
(Date:4/23/2014)... have found evidence of an interaction between prenatal ... behavior in children, especially in girls. , "The ... to prenatal smoking will have behavioral problems. ... Boutwell, Assistant Professor at Sam Houston State University, ... the study. "One possible explanation for this ...
Breaking Biology News(10 mins):Halving hydrogen 2Halving hydrogen 3Halving hydrogen 4Study finds long-term survival of human neural stem cells transplanted into primate brain 2Genetics risk, prenatal smoking may predict behavioral problems 2
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