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Glycol in Medical News
Polyethylene Glycol Offers Relief to Chronic Constipation
The study, published in The American Journal of Gastroenterology, indicates that a clinical trial including 50 medical centers and 304 patients has confirmed that polyethylene (PEG) laxative is safe for patients suffering from chronic constipation, even elderly patients can use the drug safely fo...Ecigarettesnational.com Says Claim by FDA and Other Health Organizations Intentionally Misleading
...cadmium, nickel, radioactive Polonium 210, cyanide, butane, arsenic, acetone ... the list goes on into the thousands. And they found ... 1% diethylene glycol in 1 out of 18 cartridges?" The doctors that performed the studies are also falling under scrutiny, because the public at large knows nothing a......odels are available at the 8 degree C temperature threshold. Certified glycol min/max thermometers are used in refrigerators and can be programmed to sou...when temperature limits are exceeded. Because the sensor is surrounded by a glycol solution, they are not susceptible to ambient temperature changes when the ...
...ay that it is actively pursuing the development of proprietary polyethylene glycol (PEG) synthetic sealants as part of its global commercialization strategy f...or unanticipated events as they occur. (1) Fibrin versus polyethylene glycol sealant: an experimental study in rabbits." European Journal of Plastic S...
Water method for unsedated colonoscopy; interval between prep and colonoscopy predicts prep quality
...ty to tolerate previous bowel preparations and on the presence of renal insufficiency and other comorbidities. The preparations used were polyethelene glycol electrolyte-based (PEG) and sodium phosphate (SP) solution (71 percent), oral PEG and magnesium citrate (23 percent), or SP alone (6 percent). The tim...New Standards Set for Heparin and Glycerin
... might be contaminated with toxins called ethylene glycol and diethylene glycol," said USP Chief Science Off...ch as toothpaste and pancake syrup, while ethylene glycol and diethylene glycol are poisonous. Switching ethylene glycol, which is...Preemies Exposed to Toxins in Liquid Meds
... During their treatment, the infants were regularly exposed to 20 different excipients, including ethanol (found in iron and furosemide) and propylene glycol (found in dexamethasone). These chemicals can cause nerve damage. The infants' exposure to ethanol ranged from 0.2 ml to 1.8 ml a week, equivalent ...Cell transplantation and diabetes: New sites, new devices
...Finally, the research team suggested decreasing capsule size to nano-scale and combining PEGylation coating of capsules with a layer of poly(ethylene) glycol molecules with low-dose immunosuppression to improve engraftment and long-term function. Contact: Dr. Cherie Stabler, Department of Biomedical Engin...Green Apple Cleaners Expands Reach to Health Conscious Customers
... safe profile and cleaning ability, is a propylene glycol ether that is completely and readily biodegradable into water and CO2. These propylene glycol ethers should not to be confused with ethylene glycol ethers, the variety found in products like anti-fr...Raising the Bar on MonoPropyleneGlycol USP/EP
...Administration, U.S. Department of Agriculture, European Union, Australia, Japan, Canada and New Zealand all endorse the HACCP system. MonoPropylene glycol USP/EP is used as a humectant and emulsifier in the production of food additives, personal care products and other everyday items. It is also used as ...Glycol in Medical Technology
Insmed Initiates Clinical Study for Follow-on Biologic Version of Neulasta(R)
...." About INS-20 Pegylated recombinant human G-CSF is a chemically modified version of G-CSF in which a water soluble polymer called polyethylene glycol is attached to the protein. The pegylated protein has a prolonged biological activity after it is injected into the patient. This allows less frequent...Shingles Pain Treatment Will Benefit More Patients
...to inflamed or injured skin (e.g. active herpes zoster lesions, atopic dermatitis or wounds), mucous membranes or the eyes. Plasters contain propylene glycol which may cause skin irritation, methyl parahydroxybenzoate and propyl parahydroxybenzoate which may cause allergic reactions. Use with caution in pat...Halozyme Therapeutics Announces Positive Findings With Pegylated Enzyme in Prostate Cancer Models
...a more rapid reduction of tumor volume that could potentially improve patient survival. Pegylation refers to the covalent attachment of polyethylene glycol to a molecule, usually a drug or therapeutic protein. A pegylated molecule may be masked from the immune system and have a prolonged circulatory time ...Nektar Announces Expanded Phase 2 Clinical Development Plan For NKTR-102 (PEG-irinotecan)
...so be used to modify pharmaceutical agents to preferentially target certain systems within the body. It is a technique in which non-toxic polyethylene glycol (PEG) polymers are attached to therapeutic agents, and it is applicable to most major drug classes, including proteins, peptides, antibody fragments, ......arget certain systems within the body and reduce penetration of drug across the blood-brain barrier. It is a technique in which non-toxic polyethylene glycol (PEG) polymers are attached to therapeutic agents, and it is applicable to most major drug classes, including proteins, peptides, antibody fragments, ...
Insmed Provides Update on Follow-On Biologics and IPLEX(TM) Programs
...(R). About INS-20 Pegylated recombinant human G-CSF is a chemically modified version of G-CSF in which a water soluble polymer called polyethylene glycol is attached to the protein. The pegylated protein has a prolonged biological activity after it is injected into the patient. This allows less frequent......so be used to modify pharmaceutical agents to preferentially target certain systems within the body. It is a technique in which non-toxic polyethylene glycol (PEG) polymers are attached to therapeutic agents, and it is applicable to most major drug classes, including proteins, peptides, antibody fragments, ...
...technology is a modular, multi-component delivery vector that carries active siRNA molecules in its core with the flexibility to attach a Polyethylene glycol (PEG) layer and/or a targeting ligand to the polymer-siRNA NPX to improve circulation half life and achieve selective distribution to the target tissu...
.../www.nektar.com/wt/page/nktr102media C10: "NKTR-102, a novel polyethylene glycol conjugate of irinotecan, has improved antitumor activity in three mouse xen... systems within the body. It is a technique in which non-toxic polyethylene glycol (PEG) polymers are attached to therapeutic agents, and it is applicable to ...
...so be used to modify pharmaceutical agents to preferentially target certain systems within the body. It is a technique in which non-toxic polyethylene glycol (PEG) polymers are attached to therapeutic agents, and it is applicable to most major drug classes, including proteins, peptides, antibody fragments, ...
Glycol in Medical Products
Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories
Company:ARUP Laboratories
Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories
Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories
Description:... The DuraSeal System includes an innovative polyethylene glycol hydrogel sealant and applicator packaged in a single-use kit which can be stored at room temperature for convenience and quick preparation....
Company:Confluent Surgical
Company:Hoefer, Inc.
Company:Hoefer, Inc.
Description:... The freezer is constructed with built-in bags as in a suspension file system, in which the plasma bags are placed without contacting the ethylene glycol and without having to lift cold and heavy inserts. This device ensures easy handling and maximum surface freezing concurrently with sealing the immers...
Company:Hettich Laborapparate
Description:... The freezer is constructed with built-in bags as in a suspension file system, in which the plasma bags are placed without contacting the ethylene glycol and without having to lift cold and heavy inserts. This device ensures easy handling and maximum surface freezing concurrently with sealing the immers...
Company:Hettich Laborapparate
Description:...cryostat) or sliding microtome. It also simplifies the mounting of tissue sections embedded in a water-miscible supporting medium such as polyethylene glycol (PEG)....
Company:myNeuroLab.com
Company:ARUP Laboratories
3-Methoxy-4-Hydroxyphenylethylene Glycol (MHPG)
Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...Company:ARUP Laboratories
Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories
Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories
Description:... The DuraSeal System includes an innovative polyethylene glycol hydrogel sealant and applicator packaged in a single-use kit which can be stored at room temperature for convenience and quick preparation....
Company:Confluent Surgical
HE 33 Mini Submarine unit, Complete
Description:...2 samples. Combs of 1.0 or 1.5 mm thickness come with 8, 12, or 16 wells. The units clear base acts as a cooling chamber. Fill with 50% ethylene glycol coolant mixtureapproximately 500 mland seal. Keep the base stored in the freezer. The UV transparent running tray can be placed on a transilluminat...Company:Hoefer, Inc.
HE 33 Mini Submarine unit, Basic
Description:...2 samples. Combs of 1.0 or 1.5 mm thickness come with 8, 12, or 16 wells. The units clear base acts as a cooling chamber. Fill with 50% ethylene glycol coolant mixtureapproximately 500 mland seal. Keep the base stored in the freezer. The UV transparent running tray can be placed on a transilluminat...Company:Hoefer, Inc.
Description:... The freezer is constructed with built-in bags as in a suspension file system, in which the plasma bags are placed without contacting the ethylene glycol and without having to lift cold and heavy inserts. This device ensures easy handling and maximum surface freezing concurrently with sealing the immers...
Company:Hettich Laborapparate
Description:... The freezer is constructed with built-in bags as in a suspension file system, in which the plasma bags are placed without contacting the ethylene glycol and without having to lift cold and heavy inserts. This device ensures easy handling and maximum surface freezing concurrently with sealing the immers...
Company:Hettich Laborapparate
Description:...cryostat) or sliding microtome. It also simplifies the mounting of tissue sections embedded in a water-miscible supporting medium such as polyethylene glycol (PEG)....
Company:myNeuroLab.com
Glycol in Medical Dictionary
Ethylene glycol is an organic compound widely used as an automotive antifreeze and a precursor to polymers. In its pure form, it is an odorless, colorless, syrupy, sweet tasting liquid. Ethylene glycol poisoning is caused by the ingestion of ethylene glycol . Ethylene glycol is most ...
...antiseptic ... What is the structure of propyl alcohol ? ... propyl n. A univalent organic radical with composition C 3 H 7 , ... Propylene glycol propyl paraben sodium lauryl sulfate stearyl alcohol safe to your skin? ... Propyl alcohol Christina Care Health System Wilmington, Dela...
...oms is important—many pet ... Antifreeze poisoning occurs in two phases. ... antifreeze ( ) n. A substance, often a liquid such as ethylene glycol or alcohol, mixed with another liquid to lower its freezing Your antifreeze headquarters. For over 50 years, PEAK Antifreeze and Coolant has ...
...antiseptic ... What is the structure of propyl alcohol ? ... propyl n. A univalent organic radical with composition C 3 H 7 , ... Propylene glycol propyl paraben sodium lauryl sulfate stearyl alcohol safe to your skin? ... Propyl alcohol Christina Care Health System Wilmington, Dela...
...oms is important—many pet ... Antifreeze poisoning occurs in two phases. ... antifreeze ( ) n. A substance, often a liquid such as ethylene glycol or alcohol, mixed with another liquid to lower its freezing Your antifreeze headquarters. For over 50 years, PEAK Antifreeze and Coolant has ...
Glycol in Biological News
Infant formula adulteration with melamine underscores need for better detection methods
...s for food and drug ingredients allow such adulteration to affect people worldwide, which is what happened in similar instances where toxic diethylene glycol was substituted for the sweetener glycerin in toothpaste and cough syrup. USP is a scientific nonprofit organization that sets official standards for ...Drugs needed to preserve eggs for reproduction need to be given in stages
... used cryoprotectants dimethylsulfoxide, ethylene glycol and propylene glycol permeate monkey eggs. Faster permeability is bett...loading and removal times. They found propylene glycol works best in monkeys. The drug penetrated the egg...Food counterfeiting, contamination outpace international regulatory systems
...as a more premium species; milk and pet food adulterated with melamine; catfish containing banned antibiotics; toothpaste contaminated with diethylene glycol (a base chemical in antifreeze); and canned energy drinks of unknown origin labeled with brand names. Pharmaceutical counterfeiting has attracted m...Tailor-made recombinant proteins in mammals
...nything you want on the tagged protein," she says, "You attach small molecule drugs, or polymers that change the pharmacokinetics such as polyethylene glycol polymers, or another protein molecule, or anything you're interested in attaching to a protein." Because of their obvious therapeutic importance, t...American Chemical Society's Weekly PressPac -- Dec. 17, 2008
...otein's effects. The scientists found that laboratory rats absorbed 10 times more LF if the protein is coated with the polymer, called polyethylene glycol (PEG). In addition, the coated PEG remained active in the bloodstream longer than the uncoated protein. The scientists also showed that the coated dr...UC Davis researchers discover Achilles' heel in pancreatic cancer
...es of pancreatic cell lines using arginine deiminase, an enzyme isolated from a Mycoplasma bacteria. The enzyme was modified by adding polyethylene glycol chains to increase size and circulatory time. The researchers found that exposing the pancreatic cancer cell lines to the modified arginine deimina...Reversible 3-D cell culture gel invented
...rting between a gel and a liquid state is known as thixotropy. IBN's thixotropic gel is synthesized from a nanocomposite of silica and polyethylene glycol (PEG) under room temperature, without special storage conditions. This novel material facilitates the safe and convenient culture of cells in 3D since...Slipping through cell walls, nanotubes deliver high-potency punch to cancer tumors in mice
...r words, you don't get this result just by attaching drugs to any nanotubes." The researchers used nanotubes that they had coated with polyethylene glycol (PEG), a common ingredient in cosmetics. The PEG they used was a form that has three little branches sprouting from a central trunk. Stuffing the trun...Cancer drug delivery research at Case Western Reserve University cuts time from days to hours
...uman body, and has a versatile surface chemistry, large surface-to-volume ratio and variable size and shape. Each Au NP is coated with polyethylene glycol (PEG) ligands, giving it the appearance of a hairy ball, said Burda. These PEG molecules offer several advantages over other materials: they are solub......e interstellar molecules known to date have been found, including the most complex ones such as ethyl alcohol, formaldehyde, formic acid, acetic acid, glycol aldehyde (a basic sugar), and ethylene glycol. Starting from 1965, more than 140 molecular species have been detected in space, in interstellar clo...
Glycol in Biological Technology
Sangart, Inc. Completes Series F Funding Round
...herapeutics The MP4 molecule is the basis for Sangart's oxygen therapeutic product platform. The MP4 molecule is created using unique polyethylene glycol conjugation with human hemoglobin and was specifically designed to the optimal molecular size, viscosity, oxygen affinity and diffusion potential to t...Sangart, Inc. Announces Key Executive Appointments and Company Restructuring
... About Hemospan(R) Sangart's lead product candidate, Hemospan(R) is an oxygen therapeutic product that is created using unique polyethylene glycol conjugation with human hemoglobin. Hemospan(R) was specifically designed to the optimal molecular size, viscosity, oxygen affinity and diffusion pote...New nanoscale process created by UCSB scientists will help computers run faster and more efficiently
...k, and one of the water-soluble blocks is polyethylene glycol. Polyethylene glycol is found in shampoos and many consumer products. It's a non-toxic, water-soluble, biocompatible polymer. By putting those together, the polyethylene glycol loves the water and the polystyrene loves the oil, and they hate each other...Zemea Propanediol Approved as a Natural Ingredient by ECOCERT
...ing international organic and natural agencies. Zemea® is the first glycol to receive ECOCERT® approval. Zemea® is a 100 percent natural ingr...ERT® certification for their products now have an ECOCERT® approved glycol to use in their formulations. They can be confident that Zemea® will a...A simple therapy for brain injury
... Severe brain injury due to blunt force trauma could be reduced by application of a simple polymer, Polyethylene glycol or PEG, mixed in sterile water and injected into the blood stream as reported in BioMed Central's Journal of Biological Engineering . Andrew Koo......immunogenicity, and reducing dosing frequency. Nektar proprietary technology uses advanced conjugation chemistry and techniques to attach polyethylene glycol polymers to therapeutic agents. About Hematide(TM) Hematide(TM), a novel, synthetic, peptide-based erythropoiesis-stimulating agent (ESA), is a pr...
...technology is a modular, multi-component delivery vector that carries active siRNA molecules in its core with the flexibility to attach a Polyethylene glycol (PEG) layer and/or a targeting ligand to the polymer-siRNA NPX to improve circulation half life and achieve selective distribution to the target tissu...
USP Announces Revised Glycerin Monograph
...r articles as well, such as toothpaste. Diethylene glycol is a poisonous chemical used in industrial solvent... intentional adulteration of drugs with diethylene glycol has occurred many times and in many countries, mos... glycerin manufacturer -- to prove that diethylene glycol is not present, using the USP Glycerin monograph. ......cted in two animal species and used the final pegylated version of rBChE for the first time. In general, the conjugation of proteins with polyethylene glycol (PEG) has been shown to decrease immunogenicity, increase circulating serum half-life and increase stability of recombinant proteins. The data from th...
...vent the polymer nanochannels from coming unstuck upon the introduction of the aqueous nanotube solution. The researchers have found that polyethylene glycol diacrylate has the right combination of properties for use as the polymer mold. It is negatively charged and facilitates conformal contact with the su...
Glycol in Biological Products
Polyethylene glycol 8000, Molecular Biology Grade from Research Organics, Inc.
Description: PEG 8000, Molecular Biology Grade...Company:Research Organics, Inc.
[14C]Polyethylene glycol 4000 from GE Healthcare, formerly Amersham Biosciences
Description: [14C]Polyethylene glycol 4000, 9.25 MBq, 250 uCi. Aqueous solution containing 3% ethanol, sterilized. 370-740 MBq/g, 10-20 mCi/g.1.85 MBq/ml, 50 uCi/ml. Category: Radiochemicals &Radiation Safety, Radiochemicals....Company:GE Healthcare, formerly Amersham Biosciences
Polyethylene Glycol 8000 from GE Healthcare, formerly Amersham Biosciences
Description: Polyethylene Glycol 8000, 1 kg. PEG 8000.Used in differential DNA precipitation. Category: Nucleotides & Enzymes & Biochemicals, Ultrapure Biochemicals ....Company:GE Healthcare, formerly Amersham Biosciences
Frozen-EZ Yeast Transformation II Kit from Zymo Research
Description:...logy laboratories. The ability to transform whole cells at high efficiencies with plasmid and linear DNAs using lithium based buffers and polyethylene glycol has made routine plasmid transformations and library screening easy and reliable, especially when compared to techniques like electroporation and sphe...Company:Zymo Research
Glycol in Biological Definition
...pan-2-ol, 2-propanol) H 3 C-CH(OH)-CH 3 , or "rubbing alcohol".
Ethylene glycol (ethane-1,2-diol) HO-CH 2 -CH 2 -OH, which is the primary component in an...l groups is commonly called a "glycol", e.g. HO-CH 2 -CH 2 -OH is ethylene glycol . The IUPAC name is ethane-1,2-diol, "diol" indicating two hydroxyl groups,...
... A DPPC bilayer simulation Color scheme: PO4 = green, N(CH3)3 = violet, water = blue, terminal CH3 = yellow, O = red, glycol C = brown, chain C = grey In biology and chemistry , a lipid bilayer is a membrane or zone of a membrane composed only of lipid molecules...
... A DPPC bilayer simulation Color scheme: PO4 = green, N(CH3)3 = violet, water = blue, terminal CH3 = yellow, O = red, glycol C = brown, chain C = grey In biology and chemistry , a lipid bilayer is a membrane or zone of a membrane composed only of lipid molecules...
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(Date:5/24/2013)... scientists have focused among other factors on drugs ... is the accumulation of A-beta that causes the known plaques ... formation of A-beta is APP. Alessia Soldano and Bassem Hassan ... APPL the fruit-fly version of APP in the ... Leuven): "We have discovered that APPL ensures that brain cells ...
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