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New binding target for oncogenic viral protein

The DNA tumor virus simian virus 40 produces the Large T antigen which inactivates two of the cell's most important cancer-preventing proteins, p53 and pRb. In a study published in the Journal of Biological Chemistry, researchers at the Fred Hutchinson Cancer Research Center report the discovery of an additional target for T antigen--a protein called Fbw7. The Fbw7 gene is located in a ch...

Ancient olfaction protein is shared by many bugs, offering new pest control target

In the battle against insect pests, new research indicates that it may all come down to the sense of smell. A group of Rockefeller University scientists who had previously identified a key gene essential for the sense of smell in fruit flies now shows that this gene's function appears to be evolutionarily conserved across very different insect species. Research by Leslie Vosshall's laborat...

Novel Enzyme Shows Potential As An Anti-HIV Target

At just 9.8 kilobases, the HIV genome pales in comparison to the 3.2 gigabases of its human and nonhuman primate targets. The compact retrovirus encodes just 14 proteins, which play different roles in promoting viral infection and virulence. As a retrovirus, HIV uses the host’s cellular machinery—including RNA polymerases, which carry out transcription—to copy its RNA genome into DNA and infiltra...

A bacterial genome reveals new targets to combat infectious disease

More than a billion people are at risk for infection with filarial nematodes, parasites that cause elephantiasis, African river blindness, and other debilitating diseases in more than 150 million people worldwide. The nematodes themselves play host to bacteria that live within their cells, but in this case, the relationship is classic mutualism, with each benefiting from the other. Indeed, the Wo...

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

Gene therapy methods that specifically target muscle may reverse the symptoms of a rare form of muscular dystrophy, according to new research in mice conducted by medical geneticists at Duke University Medical Center. Infants born with the inherited muscular disorder called Pompe disease usually die before they reach the age of two. The researchers also said their approach of targeting corrective...

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Rabbit Anti-Conjugated Quinaldic Acid Polyclonal Antibody, Unconjugated from Advanced Targeting Systems

Description:Anti-Conjugated Quinaldic Acid...
Company:Advanced Targeting Systems

Dako Target Retrieval Solution, pH 9 (x 10) from Dako

Description:Dako Target Retrieval Solution, pH 9 (x 10) This product is a Tris/EDTA buffer, pH 9, intended for heat-induced target retrieval prior to immunohistochemical staining procedures. It is well-suited for use on formalin-fixed, paraffin-embedded tissue sections mounted on glass slides. Compared with 0.01 mol/L citrate buffer, pH 6, the use of Target Retrieval Solution, pH 9, significantly impr...
Company:Dako

Dako Target Retrieval Solution, Citrate pH 6 (x 10) from Dako

Description:Dako Target Retrieval Solution, Citrate pH 6 (x 10) US regulatory status: IVD...
Company:Dako

Target Retrieval Solution, High pH, Concentrated x 10 from Dako

Description:Target Retrieval Solution, High pH, Concentrated x 10 This pH 9.9 solution is intended for heat-induced target retrievel prior to immunohistochemical staining procedures. It is for use on formalin-fixed, paraffin-embedded tissue sections mounted on glass slides. For particular antigens, target retrieval at high pH, 9.9, is especially effective. It should be noted that also endogenous bioti...
Company:Dako

Target Retrieval Solution, High pH from Dako

Description:Target Retrieval Solution, High pH This pH 9.9 solution is intended for heat-induced target retrievel prior to immunohistochemical staining procedures. It is for use on formalin-fixed, paraffin-embedded tissue sections mounted on glass slides. For particular antigens, target retrieval at high pH, 9.9, is especially effective. It should be noted that also endogenous biotin is effectively de...
Company:Dako

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Enhanced Amplification of Long Targets with PfuTurbo DNA Polymerase

DNAPolymerase Stratagene DNA polymerase* by making simple modifications to PCR reactionconditions. In this update, we d...

Development of Radioligand Binding Assays for the Motilin Receptor Using ScreenReady Targets.

Recent advances in combinatorial chemistry and genomics programs have led to an unprecedented increase in both the number of compounds and potential drug targets that can be screened. The development of automated liquid h...

Calcium Plus Assay Kit, Superior Detection for Specialized Targets

HIGHER MAXIMUM SIGNAL RAPID PROCEDURE COMPATIBLE WITH MORE TARGETS SUITABLE FOR HTS APPLICATONS The Calcium Plus Assay Kit provides a reliableand homogeneous method for detecting changesin intracellula...

National broadband policy: Let's get it right this time

Several articles have popped up that discuss the need, but do not reflect some of the keys to making it right. One <a href="http://thehill.com/thehill/export/TheHill/News/...

Wisconsin won't get Georgia biotech without a fight

And that's because Georgia is not simply willing to let go of , an Athens, Ga. business that produces neural stem cell kits for research...

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Nontarget organism

are highly toxic to Full arti...

Gene targeting

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Feeding channel created by malaria parasite - a new target for malaria treatments

Researchers have found pore-like holes in the membranes of red blood cells infected by the deadliest form of the malaria parasite. The parasite, Plasmodium falciparum, apparently uses these holes to supply itself with the nutrients it needs to grow and reproduce. The discovery may lead to the development of new treatments for malaria, a widespread and devastating disease. Mala...

Diabetic testing gets easier

Of all the problems associated with diabetes, the most painful and bothering one is the trauma of going through the daily blood tests. The worst part according to many diabetics is the finger stick. There are unfortunate patients who use the stick up to six times a day for more than ten to twenty years or so. The main obstacle of these tests is the pain and discomfort associated with them...

Dentist's note for vegetarians

Academy of General Dentistry (AGD) has warned vegans that are very low in animal products can be short of the calcium necessary to make vitamin D, which in turn strengthen teeth. Dr.Ludwig Leibsohn, faculty in AGD , said, "an adult on a vegetarian diet for a prolonged time can be at risk of periodontal disease. Teeth may soften when there is a shortage of vitamin D, becoming more susc...

Can one get addicted to fast food?

The New Scientist magazine in its January issue has reported that a regular diet of fast foods like hamburgers, fries and foods high in fat and calories may be addictive. The researchers have found that eating oneself to obesity is not just due to a lack of self-control, but is most likely due to the hormonal changes caused by the fast foods, in the body, that could impair the ability to...

Antibiotics can raise the risk of getting cancer!

A new study reveals that antibiotics if taken limitlessly can increase the risk of contracting cancer. Using antibiotics more than 10 times during childhood can increase the risk of lymphoma, //a cancer that affects the body's lymphatic system. The study, conducted by Ellen T. Chang and colleagues from the Northern California Cancer Centre in Fremont, also found heavy use of non-ste...

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NEW Padgett Model PI - Electro-Dermatome

Description:6-inch Electro-Dermatome. This is the only powered 6-inch dermatome on the market. A six inch graft can cover most adult hands or a small child's face without seams. This dermatome has been designed to run more efficiently, thus the motor volume is decreased considerably and the handle temperature is much cooler. The Electro-Dermatome is durable and cost-effective. It is affordably priced to meet...
Company:Integra LifeSciences Corporation

Multi-Target Anaglyph Stereo Test

Description:This is a versatile new test providing the broadest range of familiar stereo tests in one book. The Multi-Target Stereo test can be used for study, testing and training of binocularity, stereopsis, visual attention, form and depth perception, suppression, ESO and EXO. The Richmond version includes a pair of high quality reversible red/green anaglyph glasses with metal frames for years of use....
Company:Richmond Products, Inc.

Padgett Osteotome

Description:Padgett Osteotome...
Company:Integra LifeSciences Corporation

TargetScan Targeted Prostate Biopsy System

Description:TargetScan(R) is the latest innovation in prostate mapping, biopsy and cancer treatment guidance. Combining 3-D image acquisition with a stationary probe, this new technology helps physicians plan and execute targeted prostate biopsies -- potentially improving patients' cancer treatment outcomes with less-invasive procedures....
Company:Envisioneering Medical Technology

IMAGETEAM™ (IT)3870 cordless scanner

Description:The IMAGETEAMTM (IT)3870 cordless scanner addresses the needs of many applications. It is designed for tough use, such as in healthcareThe cordless scanner is also ideal for manufacturing, such as work-in-process, where safety may be anissue. Eliminating the cables prevents the cord from getting entangled in equipment, thus avoiding the chance of an accident. Other applications include interfaci...
Company:InfoLogix, Inc.

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Breast Cancer and HER-2/neu: Diagnostic Tools for Targeted Therapy

Contributing Editor With over 200,000 new cases and 40,000 deaths per year, breast cancer undoubtedly qualifies as one of Americas most serious health problems. Recently, efforts to develop early detection methods and more effective therapy have made important progress. This is particularly...

Molecular Target of Bradmer's Neuradiab Further Validated by Independent Findings

TSX: BMR TORONTO, July 10, 2007 /PRNewswire-FirstCall/ - BradmerPharmaceuticals Inc., a biopharmaceutical company dedicated to thedevelopment and commercialization of cancer therapies, todayannounced that new research published by an independent team inBasel, Switzerland validates tenascin as an important moleculartarget for the development of new treatments for glioblastomamultiforme (G...

Gene Therapy Eradicates Pancreatic Cancer in Preclinical Trial Targeting System's Success in Mouse Model Reported in Cancer Cell

HOUSTON, July 9, 2007 - A molecularly engineeredtherapy selectively embeds a gene in pancreatic cancer that shrinksor eradicates tumors, inhibits metastasis, and prolongs survivalwith virtually no toxicity, researchers from The University ofTexas M. D. Anderson Cancer Center report in the July 9 edition ofCancer Cell. "This vehicle, or vector, is so targeted and robust in itscanc...

Fat Kills Cancer: Turning Stem Cells from Fat Tissue into Personalized, Cancer-Targeted Therapeutics

PHILADELPHIA, July 3, 2007 ? Researchers in Slovakia havebeen able to derive mesenchymal stem cells from human adipose, orfat, tissue and engineer them into “suicide genes” that seek out and destroy tumors like tiny homing missiles. This gene therapy approach is a novel way to attack smalltumor metastases that evade current detection techniques andtreatments, the researchers...

Two Phase III clinical trials on corifollitropin alfa (Org 36286) reach randomization target

OSS, the Netherlands, June 27, 2007-Organon, the humanhealthcare business unit of Akzo Nobel, announced today that twoout of three Phase III clinical trials with corifollitropin alfa(Org 36286), a new long-acting fertility hormone, have reachedtheir randomization target. Corifollitropin alfa is a new recombinant fertility hormone. It isthe first of a new class of gonadotropi...

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Vegetarianism

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