Genome

Man and mouse share genome structures

In the most detailed large-scale study to date of the proteins that package DNA, researchers have mapped a family of switches that turn genes on and off. Their findings may help scientists understand regulatory mechanisms underlying cancer and human development. The research team includes first author Bradley Bernstein, recipient of a Howard Hughes Medical Institute (HHMI) physician postd...

Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer

The genome sequence of the parasitic amoeba Entamoeba histolytica, a leading cause of severe diarrheal disease in developing countries, includes an unexpectedly complex repertoire of sensory genes as well as a variety of bacterial-like genes that contribute to the organism's unique biology. The report, which appears in the February 24 issue of Nature, presents the first genome-wide study...

Affymetrix Unveils Plans to Double Plant and Animal Genome Microarray Offering

Sacramento - Today, Affymetrix, Inc.announced plans to make eight new GeneChip(R) plant and animal genomearrays available in 2005 as part of its Consortia Program, includingcanine, Rhesus macaque, Medicago trancatula (legume), Brassica, tomato,citrus, poplar and sugar cane. More than 20 research presentations atthis week's Plant and Animal Genome Conference XIII in San Diego,Calif. feature...

Whole genome fine map of rice completed

After the completion of a draft sequence of the Chinese hybrid rice genome, which was published in the Journal Science in 2002, CAS researchers have recently finished the fine map of the rice genome. In an article published by the recent issue of PLoS Biology (Vol.3 Issue 2, 2005), scientists led by the Beijing Institute of Genomics (BIG) reported a "much improved, near-complete genome analysis o...

Genome-wide mouse study yields link to human leukemia

Thanks to a handful of very special mice, scientists have discovered a new tumor suppressor gene and a unique chemical signature implicated in the development of human leukemia, findings that open up a "treasure box" of opportunity and possibility, study authors say. Researchers in The Ohio State University Comprehensive Cancer Center bred a type of mouse that develops acute lymphoblastic...

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Genome at Biology Products

S. pombe Whole Genome ChIP-on-chip from Agilent Technologies

Description:The S. pombe Whole Genome ChIP-on-chip Microarray is specifically designed for location analysis of yeast (S. pombe) DNA binding proteins by pairing chromatin immunoprecipitation (ChIP) with Agilent DNA microarrays. This set delivers robust hybridization and reliable binding data with greater true binding events and fewer false positives. In addition, Agilent provides flexibility by offering both...
Company:Agilent Technologies

S. cerevisiae yeast Whole Genome from Agilent Technologies

Description:The Yeast Whole Genome ChIP-on-chip Microarray is specifically designed for location analysis of yeast (S. cerevisiae) DNA binding proteins by pairing chromatin immunoprecipitation (ChIP) with Agilent DNA microarrays. This set delivers robust hybridization and reliable binding data with greater true binding events and fewer false positives. In addition, Agilent provides flexibility by offering bo...
Company:Agilent Technologies

S. cerevisiae yeast Whole Genome from Agilent Technologies

Description:The Yeast Whole Genome ChIP-on-chip Microarray is specifically designed for location analysis of yeast (S. cerevisiae) DNA binding proteins by pairing chromatin immunoprecipitation (ChIP) with Agilent DNA microarrays. This set delivers robust hybridization and reliable binding data with greater true binding events and fewer false positives. In addition, Agilent provides flexibility by offering bo...
Company:Agilent Technologies

HP GenomeWide siRNA from QIAGEN

Description:For knockdown of all human, mouse, and rat genes using predesigned siRNAs...
Company:QIAGEN

Genome Sequencer 20 System from Roche Applied Science

Description:The Genome Sequencer 20 System revolutionizes DNA sequencing, delivering sequence data in a massively parallel fashion. The instrument is the center...
Company:Roche Applied Science

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Genome at Biology Technology

New BL21-CodonPlus Cells Correct Codon Bias in GC-Rich Genomes

Carsten-Peter Carstens Julie Bonnardel Anna Waesche Ronda Allen Stratagene Codon bias is a significant obstacle for efficient expression ofheterologous genes in E. coli hosts. In GC-rich genomes, such as mammals,rare arginine codons (AGG or AGA) and the proline codon (CCC) most fre...

Whole Genomes From Microbes to Man

Madison, WI-- Optical Mapping is a new technology that will be used to discover why patients experience toxic side effects, or fail to respond to medication and to identify the causes of antibiotic resistance and virulence in pathogenic organisms. Wisconsin- based OpGen, has announced the commercial launch of its Optical Mapping(TM) system for rapid, cost-effective analysis of whole genomes, from...

WHOLE GENOME SEQUENCING

Agencourt offers whole genome services that can encompass all aspects of genome projects from shotgun library construction through genome annotation and pathway mapping. Our personal project managers consult with clients to design a sequencing strategy to meet their specific project goals and are available to manage th...

Protocol for GenomePlex Whole Genome Amplification from Buccal Swab

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Protocol for GenomePlex Whole Genome Amplification from Blood Card

Application Guide I. II. III. IV. V. VI. Quantificat...

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Genome at Biology Definition

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Genome at Biology Dictionary

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Genome at Medicine News

Human Genome Project Achieves Technological Triumph

The completion of rough draft sequence of the human genes is a major scientific milestone and was achieved on 26.06.2000. The project began more than 10 years ago to map out almost 35 billion chemical letters that make up the recipe of human life. This breakthrough is expected to revolutionize the practice of medicine by paving the way for new drugs and medical therapies.Specific sequences...

Controversial deal on public access of the human genome map

, which is a much talked about topic, considering that the mapping of the genes will enable one to have the information to manipulate individual characteristics like the color of the eye or even skin. It will also help say whether a cell will function normall...

Innovative yeast genome may handle Cancer Clues

According to scientists mapping of have mapped all the genes in a second type of yeast that they hope will provide new insights into basic cell biology and the development of cancer.A team of international scientists led by Nobel medicine laureate Sir Paul Nurse of the charity Cancer Research UK has sequenced the genome of fission yeast, a cousin of the brewer's yeast whose genome// was mapped.<b...

Primates reveal a new dimension to human genome

Two laboratories at Berkeley, California have come out with a tremendous technique that would tell out the entire multitude of information held in store in the human genome. This new technique which is called "phylogenetic shadowing". An analysis through this technique helps to elucidate comparisons between the DNA sequences// in humans and primates. Phylogenetic shadowing enables a complete stud...

Human Diseases May Have Clue In Human-Chimp Genome Difference

In a study by a researcher from University of California, San Diego, suggests that the clues of human diseases are found not in the similarity of the genome sequences between man and chimpanzee but the differences// in them. Researcher had described genetic differences between the species: one, the discovery of the first human-specific protein that is also expressed in brain cells asso...

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Genome at Medicine Products

GenomeLab SNPstream Genotyping System

Description:The GenomeLab SNPstream Genotyping System provides an automated scalable system capable of performing from 4,600 to over 800,000 SNP genotypes per day. Combined with multiplexing capabilities, experimental layouts and operational flexibility, this enables you to process a wide range of studies. SNPstream is a robust solution designed to deliver your intended results faster with less effort, while...
Company:Beckman Coulter, Inc.

Genome at Medicine Technology

Human Genome Sciences Reports That a Phase 2 Study of LymphoStat-B Showed Significant Reductions in Disease Activity in Patients with Active Systemic Lupus Erythematosus

-LymphoStat-B(R) significantly reduced signs and symptoms of SLEdisease at 52 Weeks and demonstrated durable clinical andbiological activity at 76 weeks- ROCKVILLE, Md., June 14, 2007 /PRNewswire-FirstCall/ -- HumanGenome Sciences, Inc. today announced the presentation of Phase 2trial data demonstrating that LymphoStat-B(R) (belimumab)significantly reduced disease activity across multiple...

Human Genome Sciences Announces Positive Final Results Of Phase 2b Trial of Albuferon

- Albuferon 900-mcg dosed every two weeks achieved an SVR rate atleast comparable to Pegasys dosed every week (ITT analysis), withmore favorable quality-of-life scores - ROCKVILLE, Md., June 07, 2007 /PRNewswire-FirstCall/ -- HumanGenome Sciences, Inc. today announced the top-line final results ofa Phase 2b clinical trial of Albuferon(R) (albinterferon alfa-2b)in combination with ribaviri...

Human Genome Sciences Reports Growing Evidence That Its TRAIL Receptor Antibodies Have Significant Potential in the Treatment of a Broad Range of Cancers

- Journal of Clinical Oncology publishes first clinical study ofHGS-ETR1 - ROCKVILLE, Md., April 27, 2007 /PRNewswire-FirstCall/ -- HumanGenome Sciences, Inc. today reported that clinical and preclinicalevidence continues to emerge demonstrating that its TRAIL receptorantibodies, HGS-ETR1 (mapatumumab) and HGS-ETR2 (lexatumumab), havesignificant potential for use in the treatment of a bro...

GenoMed Prevents Sickle Cell Pain for Over a Year

ST. LOUIS--(BUSINESS WIRE)--Mar 12, 2007 - GenoMed (OTC PinkSheets:GMED), the Next Generation Disease Management company whosebusiness is public health(TM), announced today publication of acase report of a sickle cell patient whose pain has disappeared forover a year thanks to GenoMed's treatment. The patient is a middle-aged African American woman who foryears required multiple pain pill...