Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down
For patients with high-risk breast cancer treated with radical mastectomy and adjuvant chemotherapy, the addition of radiation therapy leads to better survival outcomes with few long-term toxic effects, according to a 20-year follow-up of a randomized trial, which appears in the January 19 issue of the Journal of the National Cancer Institute. The British Columbia randomized radiation the...It's not all genetic: Common epigenetic problem doubles cancer risk in mice
In experiments with mice, a team of scientists from the United States, Sweden and Japan has discovered that having a double dose of one protein is sufficient to change the normal balance of cells within the lining of the colon, thereby doubling the risk that a cancer-causing genetic mutation will trigger a tumor there. Roughly 10 percent of people have this double protein dose as well. In...Scientists detect probable genetic cause of some Parkinson's disease cases
Two new studies strongly suggest that amutation in a recently discovered gene is the most common genetic causeof Parkinson's disease identified to date. The discovery by aninternational research team provides fresh evidence that genetics maycontribute to the development of some cases of Parkinson's disease. Thefindings could lead to the development of a genetic test to detect themutation in...Mouse brain tumors mimic those in human genetic disorder
A recently developed mouse model of braintumors common in the genetic disorder neurofibromatosis 1 (NF1)successfully mimics the human condition and provides unique insightinto tumor development, diagnosis and treatment, according toresearchers at Washington University School of Medicine in St. Louis.After validating their animal model, the team made two importantdiscoveries: New blood vesse...Genetically modified natural killer immune cells attack, kill leukemia cells
Natural killer (NK) immune system cells can be genetically modified to brandish a powerful "on-switch" that prompts them to aggressively attack and kill leukemic cells. This finding, from researchers at St. Jude Children's Research Hospital, suggests a way to improve the outcome of children who receive treatment for acute lymphoblastic leukemia (ALL) or other blood cancers. Results of the...CEQ 8800 Genetic Analysis System from Beckman Coulter
Description:The CEQ 8800 Genetic Analysis System, which processes two 96-well plates and tracks the samples. This automated system adds a higher level of throughput to the CEQ product line. The CEQ 8800, part of Beckman Coulters new GenomeLab family of products*, also offers a bar coding link with the Biomek series liquid handers, for increased automation. The CEQ 8800 automates and integrates the majo...CEQ 8000 Genetic Analysis System from Beckman Coulter
Description:Simplify the process and you reduce the chance of error. Thats the safeguard built into the CEQ 8000. Developed using Beckman Coulters extensive experience in laboratory automation and leadership in capillary electrophoresis technology, the CEQ 8000 is a fully automated genetic analysis system. This system automatically fills the capillary array with a patented linear polyacrylamide (LPA) gel, de...LNA-ISH Cytogenetics - Human centromere alpha satelliteISH probes from Exiqon
Description:Exiqons LNA technology enables sensitive, fast and specific detection of chromosomal sequences directly on intact chromosomes. Related Conte...GenomeLab GeXP Genetic Analysis System from Beckman Coulter
Description:The GenomeLab GeXP Genetic Analysis System provides high-throughput, quantitative gene expression analysis via scalable, multiplexed PCR*. The systems patented priming strategy overcomes the biases that limit standard multiplexed PCR analysis to just a few genes at a time. GenomeLab GeXP delivers more genes per reaction and more samples per run, removing bottlenecks in gene expression studies f...CEQ 8000 Genetic Analysis System from Beckman Coulter
Description:Simplify the process and you reduce the chance of error. Thats the safeguard built into the CEQ 8000. Developed using Beckman Coulters extensive experience in laboratory automation and leadership in capillary electrophoresis technology, the CEQ 8000 is a fully automated genetic analysis system. This system automatically fills the capillary array with a patented linear polyacrylamide (LPA) gel, de...Map and Link Human Genetic Disorders with SSLP Analysis
system Medical Genetics Branch, National Human Genome Research Institute NationalInstitutes of Health, Bethesda, MD system is idealfor analyzing SSLPs (simple sequence-lengt...Third Wave receives FDA clearance of pharmacogenetic test
It is the first pharmacogenetic test to be approved by the FDA for use as a companion diagnostic to a specific drug therapy. The test is c...Genetic Dentistry: Your Dentist may be able to grow you a new set of Teeth.
Researchers at the University of Texas Health Science Center at San Antonio have successfully regrown mouse teeth in a petri dish from single mouse cells - and they think humans are next. They hope to push the research in the direction where they could take initial tissue from a [human] patient, put it in a culture dish and grow a tooth for them.To accomplish this seemingly futuristic feat,...Crowning glory of 2000!!! Cracking of the genetic code is top of tops
With the New Year elbowing out the old year it is time to reflect on the good old year and all the research work of 2000. And when we do that the first and foremost medical breakthrough, which comes to our mind, is the cracking of the genetic code. Almost all the top ten lists released by every one connected with the world of medicine features this remarkable feat in a prominent place and a major...Genetic influence in menopause
Genes generally control menopause in women. Many women will be aware that they probably started their menopause at around the same age as their mother or sister. But the link between the menopause and genetics has not been established by scientific evidence till now. Researchers in Utrecht and Wageningen in the Netherlands have collected data from 243 non-twin sisters in 118 families...Genetics and cholesterol levels
According to a twin study reveals that cholesterol levels are controlled by both genes and dietary factors. People with high blood cholesterol are often advised to go on a low-fat diet - or to take cholesterol-lowering drugs. It's known that reducing fat intake can reduce cholesterol levels. But there is also a genetic condition called familial hypercholesterolaemia (FH) which leads to high chole...Genetics helps in attacking cancer
According to a new study, a trial of a new anti-cancer drug interacts with specific genes, which may help refine future treatments. Ceflatonin, a natural product, is being tested as an anti-cancer treatment. Meanwhile, the US company ChemGenex is looking at the effect of the drug on the genes that are activated in cancer. They find that specific genes and cellular pathways are affected by ceflat...CEQ™ 8800 Genetic Analysis System
Description:The CEQ 8800 features unique DNA sequencing reagents including linear polyacrylamide gel (LPA), coated capillaries, ITP chemistry and cyanine-based infrared dyes- coupled with online denaturation. This results in less correction, ore meaningful raw data, and higher-quality final analyses. All of which enables the CEQ 8800 to resolve complex sequences, filling in the gaps with high-quality sequ...CEQ™ 8000 Genetic Analysis System
Description:CEQ 8000 is a fully automated genetic analysis system. This system automatically fills the capillary array with a patented linear polyacrylamide (LPA) gel, denatures and loads the sample, applies the voltage program, and analyzes the data. Software tools let you rapidly review data quality and even customize automated data assessment. All to ensure unprecedented run-to-run consistency, simplifyin...Genetic Systems HIV-1/HIV-2 Peptide EIA
Description:EIA for Donor Screening. Synthetic peptide Enzyme Immunoassay (EIA) for the detection of antibodies to Human Immunodeficiency Virus Types 1 and/or 2(HIV-1 and HIV-2) in human serum, plasma or cadaveric serum specimens....Genetic Systems HIV-1 Western Blot
Description:Donor Screening, Supplemental Confirmatory (Western Blot): The Genetic Systems HIV-1 Western Blot is a supplemental, more specific test for the detection of antibodies to HIV-1. The solid phase antigens are derived from LAV strain of HIV-1 grown in the CEM cell line. Use of the CEM cell line, which is devoid of HLA Class ll antigens, helps reduce cross reactivity to cell related, nonviral bands....ABI PRISM 310 Genetic Analyzer
Description:The ABI PRISM 310 Genetic Analyzer is an automated single-capillary genetic analyzer designed for a wide range of sequencing and fragment analysis applications. An affordable, versatile, analyzer for academic and forensic labs who incorporate genetic analysis into their work. The 310 Genetic Analyzer -- the ideal alternative to gel-based DNA analysis for any research, clinical, or forensi...Genetic Analysis Systems Enter the Clinical Mainstream
Like many other diagnostic regimes that were previously restricted to large specialty laboratories, genetic analysis is entering the clinical mainstream. Smaller, simpler analyzer systems are now suitable and affordable for hospital or large physicians group labs, while some genetic test kits are becoming available for primary point of care locations such as clinics and physician offices.<...Genetics Journal Thimerosal/Autism Study the 'Best Science Drug Company Money Can Buy'
Critique of Industry-Funded Immune Globulin Study Uncovers SampleManipulation, Design Flaws NIXA, Mo., June 26, 2007 /PRNewswire-USNewswire/ -- An analysisreleased today critically examined a recent industry-sponsoredstudy ruling out a link between autism and Rh immune globulin(RhIg) injections, some of which contained the mercury-basedpreservative thimerosal. Besides extensive design fla...Targeted Genetics Reports Inflammatory Arthritis Clinical Data at European Rheumatology Conference
BARCELONA, SPAIN and SEATTLE, WA -- (MARKET WIRE) -- June 14,2007 -- Targeted Genetics Corporation (NASDAQ: TGEN) today isreporting data from the dose escalation arm of the ongoing PhaseI/II clinical study of tgAAC94 in patients with inflammatoryarthritis. Philip J. Mease, M.D., clinical professor at theUniversity of Washington School of Medicine, chief of rheumatologyclinical research a...