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Genes in Medical News

Silenced genes as a warning sign of blood cancer

In many types of cancer, parts of the genetic material of tumor cells are switched off by chemical labels called methyl groups. This kind of methyl labeling ranges among the epigenetic changes that do not change the sequence of DNA building blocks. Such labels are found particularly often in genes...

'Suicide' Genes Help Slow Ovarian Tumor Growth in Mice

Treatment could be tested in women within 18 to 24 months, expert suggests THURSDAY, July 30 (HealthDay News) -- Treatment with "suicide" genes slowed ovarian tumor growth in mice and may one day offer a way to treat late-stage ovarian cancer in women, U.S. scientists say. Currently...

Nanoparticle-delivered 'Suicide' Genes Slowed Ovarian Tumor Growth

Potential late-stage ovarian cancer therapy; currently none available; Diphtheria-encoding genes delivered to tumor site by nanoparticles; Laboratory research; possible human trials about 18 months away Philadelphia (Vocus) July 29, 2009 -- Nanoparticle delivery of diph...

Five Hypertension Genes Found in Black Americans

Could be targets for new treatments, researchers say FRIDAY, July 17 (HealthDay News) -- Federal researchers have identified five genetic variants associated with high blood pressure in black Americans that could hopefully become targets for therapy to prevent and treat this major risk...

Australian researchers identify genes that cause melanoma

Scientists from the Queensland Institute of Medical Research (QIMR) have found two new genes that together double a person's risk of developing melanoma. As part of an international study, a team at QIMR, led by Professors Nick Hayward and Grant Montgomery, studied the genes of almost 6,000 pe...

Hundreds of Genes Could Be Linked to ADHD

Variations would explain different attention-disorder symptoms, study suggests THURSDAY, June 25 (HealthDay News) -- Hundreds of gene variations that may be associated with attention-deficit/hyperactivity disorder (ADHD) have been identified by U.S. researchers. Many of these genes...

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Genes in Medical Technology

ADHD Genes Found; Known to Play Roles in Neurodevelopment

-- Missing DNA Segments May Suggest Future Drug Targets -- PHILADELPHIA , June 23 /PRNewswire-USNewswire/ -- Pediatric researchers have identified hundreds of gene variations that occur more frequently in children with attention-deficit hyperactivity disorder (ADHD) than in children without ...

Mutant Genes in High-Risk Childhood Leukemias Identified

Results of collaborative study could lead to development of new diagnostic tools and a new therapeutic target in high-risk disease MEMPHIS, Tenn., May 19 /PRNewswire-USNewswire/ -- A research team has pinpointed a new class of gene mutations, which identify cases of childhood acute lymphoblas...

Autism Genes Discovered; Help Shape Connections Among Brain Cells

-Findings Suggest Biological Reasons for Altered Early Neural Development- PHILADELPHIA, April 28 /PRNewswire-USNewswire/ -- A research team has connected more of the intricate pieces of the autism puzzle, with two studies that identify genes with important contributions to the disorder. One ...

Why Wait for an Anti-Aging Drug? Researchers Interviewed on CBS-TV's 60 MINUTES Discover Longevinex(R) Nutriceutical Matrix Activates 9-Fold More Longevity Genes than Plain Resveratrol

SAN DIMAS, Calif., Jan. 25 /PRNewswire/ -- A red wine resveratrol (rez-vair-ah-trawl) pill is edging closer to being confirmed as an anti-aging pill as researchers at LifeGen Technologies in Madison, Wisconsin, who were recently interviewed on CBS-TV's 60 MINUTES, reported this past September that...

Cepheid Announces CE IVD Release of First On-Demand Test for van A/van B Genes Most Associated With Hospital-Acquired VRE Infection

CE IVD Menu Expanded to Eight On-Demand Tests for Use on the GeneXpert(R) System SUNNYVALE, Calif., Oct. 7 /PRNewswire-FirstCall/ -- Cepheid (Nasdaq: CPHD) today announced the release of Xpert(TM) vanA/vanB as a European CE IVD Mark product under the European Dir...

New Genes Found for Inflammatory Bowel Disease in Children

- Finding May Refine Drug Targets for Personalized Treatments - PHILADELPHIA, Aug. 31 /PRNewswire-USNewswire/ -- Researchers have discovered two new genes that increase the risk of developing inflammatory bowel disease (IBD) in childhood. While further study is needed to identify the spe...

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Genes in Medical Dictionary

Genes

A gene is the basic unit of heredity in a living organism. All living things depend on genes . Genes hold the information to build and maintain their cells and pass genetic traits to offspring. A modern working definition of a... Genetics, a discipline of biology, is the science of ...

Wry neck

... Wry neck ; Loxia. Causes. Torticollis may be: Inherited: Due to faulty genes ... Stiff Neck in Depth. AKA: Wry Neck , Acute Torticollis. Commo... Wry neck ; Loxia. Causes. Torticollis may be: Inherited: Due to faulty genes ... Learn more about torticollis and what physical therapists do for...

Waardenburg syndrome

...drome . ... ... known types of Waardenburg syndrome are distinguished by their ... Mutations in the EDN3, EDNRB, MITF, PAX3, SNAI2, and SOX10 genes cause Waardenburg syndrome . ... Waardenburg syndrome is a group of hereditary conditions characterized by ... Waardenburg syndrome af...

Von Hippel-lindau Disease

... Von Hippel - Lindau syndrome can be divided into two major types ... von Hippel - Lindau Disease . See How are genetic conditions and genes named? in the Handbook. ... Von Hippel Lindau Disease , St. Joseph Mercy, Ann Arbor Michigan: Von Hippel ... People with von Hippel...

Viral

...ute viral hepatitis. ... Primate immunodeficiency viruses, including HIV-1, are characterized by the presence of a number of viral accessory genes that encompass vif, vpr, vpx, vpu, and ... Tuberculosis (TB) is making a comeback in the United States today - particularly among the homeless, t...

Usher Syndrome

...e Usher Syndrome (all types) ... Usher's syndrome n. An inherited syndrome characterized by sensorineural deafness and retinitis ... genes associated with Usher syndrome . 5 Prospects for gene ... Usher syndrome is an inherited condition that causes a serious hearing loss t...
Genes in Biological News

Nanoparticle-delivered 'suicide' genes slowed ovarian tumor growth

PHILADELPHIA Nanoparticle delivery of diphtheria toxin-encoding DNA selectively expressed in ovarian cancer cells reduced the burden of ovarian tumors in mice, and researchers expect this therapy could be tested in humans within 18 to 24 months, according to a report in Cancer Research , a journ...

Mystery E. coli genes essential for survival of many species

Scientists have shown that E. coli one of the best known and extensively studied organisms in the world remains an enigma that may hold the key to human diseases, such as cancer. The team, funded by the Biotechnology and Biological Sciences Research Council (BBSRC) and based at the Univers...

Pitt team first to profile genes in acutely ill idiopathic pulmonary fibrosis patients

PITTSBURGH, July 7 The first findings from a one-of-a-kind, patient-driven effort to provide lung tissue for research might help doctors predict when patients with idiopathic pulmonary fibrosis (IPF) are becoming dangerously ill and also could point the way to interventions that could sustain the...

The tiny difference in the genes of bacteria

It is based on detecting short, repetitive DNA segments in the genome of bacteria. Every single bacterial strain has such characteristic repeats. "With this method we are able to identify bacterial strains as well as clarify their genetic relationships. Furthermore, we can show how new pathogenic ...

The tiny difference in the genes of bacteria

It is based on detecting short, repetitive DNA segments in the genome of bacteria. Every single bacterial strain has such characteristic repeats. "With this method we are able to identify bacterial strains as well as clarify their genetic relationships. Furthermore, we can show how new pathogenic ...

IFAR contributes to study that finds genes that influence the start of menstruation

(Boston, Mass.)Two scientists at the Institute for Aging Research of Hebrew SeniorLife are part of an international team of investigators that has identified genes that influence the start of menstruation, a milestone of female reproductive health that has lifelong influences on overall health. Th...

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Genes in Biological Technology

University of Lodz Invests in the Unique Cellaxess(R)HT System for Research on Multidrug Resistance Genes in Cancer

GOTHENBURG, Sweden, July 22 /PRNewswire/ -- Cellectricon, a leading provider of cell-based screening solutions for research and drug discovery, today announced its collaboration with University of Lodz, Poland. Under the agreement University of Lodz invests in Cellaxess(R)HT, the world's first...

Proteomics Study Reveals That Genes Involved in Invertebrate Longevity Have Surprising Parallels in Humans.

SALT LAKE CITY, March 13 /PRNewswire/ -- Prolexys Pharmaceuticals announced today the publication of the discovery of genes that are likely to have a role in the aging process of humans. The findings result from research on the human equivalents of proteins from simple animals which confer long l...

Mosquito genes linked to insecticide resistance may be new target in fight against malaria

Malaria remains one of the most serious diseases worldwide, claiming the lives of more than one million people per year in tropical and sub-tropical regions, the majority of whom are children under five years of age. Efforts to eliminate this mosquito-borne illness rely heavily on prevention meas...

RNAi Helps Illuminate the Inner Workings of the Cell Cycle: Synthetic RNAissance™ Genes Created by DNA2.0 Enable Key Research

DNA2.0 has designed RNAi-resistant genes that enabled a breakthrough in understanding the inner workings of the cell cycle. DNA2.0's RNAissance genes are simultaneously optimized for expression in the desired host and to escape inhibition by siRNA that is targeted to the natural gene. ...

The Michael J. Fox Foundation Awards $2 Million to Shed Light on Role of LRRK2 and Alpha-Synuclein Genes in Parkinson's Disease

NEW YORK, Jan. 15 /PRNewswire-USNewswire/ --- The Michael J. Fox Foundation for Parkinson's Research today announced approximately $2 million in total funding for seven research studies aiming to advance the ability of the Parkinson's research field, and drug makers, to therapeutically target ...

International team identifies 480 genes that control human cell division

PITTSBURGH A team of U.S., Israeli and German scientists used computational biology techniques to discover 480 genes that play a role in human cell division and to identify more than 100 of those genes that have an abnormal pattern of activation in cancer cells. Malignant cells have lost control...

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Genes in Biological Products

Genetic Mapping of Disease Genes from Promega

Description: Edited by I.H. Pawlowitzki, J.H. Edwards and E.A. Thompson (1997) • This volume covers: Linkage in dominant recessive and oligogenic disease, Model free (non-parametric) methods, Tools for gene mapping and applications....
Company:Promega

Goat Anti-BRF2 Polyclonal Antibody, Unconjugated from GeneTex

Description:...es. Background Information BRF2 is one of the multiple subunits of the RNA polymerase III transcription factor complex required for transcription of genes with promoter elements upstream of the initiation site. BRF2 is directly recruited to the TATA-box of polymerase III small nuclear RNA gene promoters ...
Company:GeneTex

Mouse Anti-Human Complex IV, assembly factor SURF1 Monoclonal Antibody, Unconjugated, Clone 21H2BG4 from MitoScience LLC

Description:...umber is consistent with it acting to catalyze Complex IV assembly. In cells where cytochrome c oxidase assembly is incomplete because of mutations in genes for structural subunits of the enzyme SURF1 is significantly over-expressed. This is evident in Rho0 fibroblasts which are missing mtDNA and hence can...
Company:MitoScience LLC

Rat Tissue Array: Brain, heart, kidney, liver, lung, muscle, spleen and stomach, each tissue from 10 female and 10 male, respectively from BioChain

Description:... Rat adult normal paraffin tissue array is designed for rapidly screening genes or proteins of interest in extensive panels of different types of tissues. Rat brain, heart, kidney, liver, lung, muscle, spleen and stomach tissues ...
Company:BioChain

GeneMaths XT from Applied Maths

Description:...rk with different layers for different data outputs, for example Cy3 and Cy5, standard deviations, error values, etc., as well as different subsets of genes and/or arrays. Also unique is the full error handling through all analysis, mining, and statistics functions....
Company:Applied Maths

MaV203 Competent Yeast Cells Library Scale from Invitrogen

Description:...s are designed for use with the ProQuest Two-Hybrid System (Figure 1). S. cerevisiae strain MaV203 contains deletions in the endogenous GAL4 and GAL80 genes for use with GAL4-based two-hybrid systems. The strain also has leu2 and trp1 mutations for selection of ProQuest bait and prey vectors. MaV203 contai...
Company:Invitrogen

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Genes in Biological Definition

Albinism

...ir. It is an inherited condition arising from the combination of recessive genes passed from both parents of an individual. A variety of problems with phot... making the usual amounts of a pigment called melanin . There are many genes which are now scientifically proven to be associated with albinism (or bett...

Alternative splicing

...uced, given a DNA sequence and pre-mRNA. (This does not necessarily negate the central dogma of genetics which is about the flow of information from genes to proteins). Since the ways of regulation are inherited, the interpretation of a mutation may be changed. It has been proposed that for eukary...

Antibiotic

...ancomycin useful for treatment. The situation is worsened by the fact that genes coding for antibiotic resistance can be transferred between bacteria, makin... an incredibly minimal intracellular parasite, being stripped down to a few genes worth of DNA or RNA and the minimal molecular equipment needed to enter...

Antibody

...vents know as somatic recombination. This is when genes are selected (variable (V), diversity (D) and join...pecifically, it is the area where these V, D and J genes are found - otherwise known as the complementarity...antigen, the immune system would require many more genes than exist in the genome . Instead, as Susumu To...

Apoptosis

...factor nuclear factor kappa B (NF-κB), which induces the expression of genes that play an important role in diverse biological processes, including cell...duate students Hilary Ellis and Chand Desai had made the first discovery of genes that encode apoptosis-inducing proteins: ced-3 and ced-4 . Ron Ellis ...

Arabidopsis

...haliana is used to study agronomic crops. The genome of Arabidopsis , consisting of five chromosomes , has been sequenced. There are 30644 known genes in the Arabidopsis genome. Arabidopsis has been used extensively in the study of the genetic basis of phototropism, chloroplast alignment, and...

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Genes in Biological Dictionary

Ribosomal DNA genes

Ribosomal DNA (rDNA) are sequences encoding ribosomal RNA. These sequences regulate amplification and transcription initiation and contain transcribed and nontranscribed spacer segments. The nucleolus consists of expanded chromosomal loops that carry transcriptional... Ribosomal RNA ...

Y chromosome

...lion base pairs (the building blocks of DNA) ... genes on the Y chromosome are among the estimated 20,000 to 25,000 total genes ... Y chromosome infertility is a conditi..., researchers say that there is a dramatic loss of genes from the human Y chromosome that could event...

X chromosome

...... The X chromosome carries a couple thousand genes but few, if any, of these have ... The X chr...lion base pairs (the building blocks of DNA) ... genes on the X chromosome are among the estimated 20,000 to 25,000 total genes ... X-chromosome or X chromosome ( ) n. The...

Vitelline membrane

...and no more bind. ... The European ... Drosophila vitelline membrane genes contain a 114 base pair ... melanogaster genes encoding vitelline membrane proteins. ... The European Bioinformatic...

Virulence

...s to the degree of pathogenicity ... Sensing Virulence ... Virulence genes are often involved in producing toxins ... Identifying and characterizing important virulence genes and determining their ... Definition of virulence from the Merriam-Web...

Urea cycle

.... The Urea Cycle . Urea is the chief nitrogenous waste of mammals. ... several inherited diseases of the urea cycle caused by mutations in genes ... Cincinnati Children's Hospital Medical Center offers information on Urea Cycle Disorder (UCD) ... A urea cycle disorder (UCD) is an inh...

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