Genes In The Interferon System Important In Systemic Lupus Erythematosus
Two genes with very strong associations withthe disease systemic lupus erythematosus (SLE) have been identified bya team of scientists headed by researchers at the Department of MedicalSciences at Uppsala University. The findings are being published todayon the Web page of the highly prestigious American Journal of HumanGenetics. "These findings are probably the first genetic pieces of ahug...Newly-discovered class of genes determines ?and restricts ?stem cell fate
Research on adult stem cells found in the skin hints at a new class of genes, according to a study from investigators at the University of Pennsylvania School of Medicine. These genes ?dubbed pangenes ?can both govern a stem cell's fate and put a hold on future differentiation until the time is right. Understanding the molecular control of these genes has implications for therapies that involve t...Inexpensive, mass-produced genes core of synthetic biology advances at UH
;progress in this area is made in the UK, too. It'll open tons ofresearch avenue, speeding the slow (and tedious) process of genecloning, or gene modification (mutations, deletions, etc). Devices the size of a pag...Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease
It's all in the packaging. How nature wraps and tags genes determines if and when they become active, according to researchers from Harvard and the Massachusetts Institute of Technology (M.I.T.). They did the largest, most detailed study to date of the protein structure that surrounds the human genome. Their findings reveal surprising and previously unknown specifics of how genes get switc...First 'atlas' of key brain genes could speed research on cancer, neurological diseases
Researchers at Dana-Farber Cancer Institutehave compiled the first atlas showing the locations of crucial generegulators, or switches that determine how different parts of the braindevelop ?and, in some cases, develop abnormally or malfunction.The scientists say the map will accelerate research on brain tumors andneurological diseases that result from mutations in these switch genes?called...In Vitro Osteogenesis Assay Kit from CHEMICON
Description:CHEMICON's In Vitro Osteogenesis Assay Kit contains all reagents necessary to efficiently differentiate MC3T3-E1cells to a mature osteoblastic lineage, as determined by staining for mineralization. In addition this kit provides all the necessary reagents and a protocol for quantifying osteogenesis using a standard plate reader. This product is useful for studying the effects of growth factors, dr...Random DNA mutagenesis Service from Yorkshire Bioscience Ltd
Description:We can introduce random mutations to the gene supplied by a customer. Mutated DNA will be then cloned into a vector of choice to obtain a library of the mutated DNA. Mutation frequency can be set to a desired value within 1-20 mutations per kb. Number of clones 106-108. Mutations can be restricted to a desired region of a gene. 106-108 clones...Breeding and Maintenance (Nonhuman Primates) from Alpha Genesis, Inc.
Description:AGI provides both long and short-term enriched housing for nonhuman primates and other laboratory animals in both quarantine and non-quarantine settings on a per diem basis. Breeding services are also available utilizing our state-of-the-art social housing and nursery facilities. In addition, AGI is equipped with on site CDC quarantine facilities. Primate housing and CDC quarantine systems...GeneSpring Workgroup from Agilent Technologies
Description:'Agilents GeneSpring Workgroup solution is a highly scalable analysis platform for managing and mining expression data in a workgroup or an enterprise setting, and is deployed in over 40 leading pharmaceutical, biotechnology, academic and government research organizations worldwide. GeneSpring Workgroup streamlines genomics research at large and multicampus organizations, and provides facilities...Skeletal Myogenesis Assay from CHEMICON
Description:CHEMICON's Skeletal Myogenesis Kit provides the reagents to efficiently differentiate mouse C2C12 myoblasts into mature skeletal myotubes. By efficiently promoting myogenic differentiation, the kit is a valuable tool in studies examining myogenesis, transcription factor regulation, and in developing strategies for muscle cell replacement therapy. By providing the means to obtain and maintain a la...Low Abundance cDNA Cloned Using Stratagenes Human Universal cDNA Library
Department of Cell Biology, Clevela...Big Blue Rodent Cell Cultures for Mutagenesis Studies
Rat and mouse embryonic cell lines are useful for in vitro mutagenesisstudies Stratagene Cloning Systems, Inc. The Big Blue rat cell line and the Big Blue transgenic mouse embryoniccell line are useful for in vitro mutagenesis studies. These cell lines are partof the Big Blue transgenic rodent mutagenesis assay system...High-Efficiency Site-Directed Mutagenesis of Large Plasmid Vectors
QuikChange XL: a highly versatile kit for site-directed mutagenesis oflarge plasmids Michael Borns Peter Vaillancourt Holly Hogrefe Jeff Braman Stratagene The QuikChange site-directed mutagenesis kit* characteristicallygenerates mutagenesis efficiencies exceeding 80%. We have created a new kit formutagenesis of large plasmid...RT-PCR Primer Sets for Human and Mouse Mismatch Repair Genes
Stratagene Cloning Systems from the cDNAsequences of mismatch repair genes. These genes code for specialized proteinsthat participate in correcting areas of base mispairing in DNA. We have...Randomize Gene Sequences with New PCR Mutagenesis Kit
GeneMorph PCR mutagenesis kit produces a unique mutational spectrum...New Way to "See" Genes, Evaluate Effectiveness of Gene Therapies Discovered
This technology essentially renders the body transparent and will allow physicians to determine whether gene therapies reach targeted cells and work as they should. "The technology is expected to help patients with cancer and other illnesses, such as cardiovascular disease. The discovery is outlined in the August 2000, issue of the journal Nature Medicine. UCLA researchers plan to tes...Altering genes through calories
It's never too late to diet. Cutting calories for only a few weeks late in life causes anti-aging changes in mouse genes.Even those averse to weight watching might have their cake and eat it if researchers can find drugs that mimic dieting’s effects. Cutting calories is known to increase lifespan and reduce age-related disease in experimental mammals. Researchers at the University of C...Vical Licensee AnGes MG Announces Positive Results of Phase 3 Angiogenesis Trial in Japan
SAN DIEGO, June 18, 2007 /PRNewswire-FirstCall/ -- VicalIncorporated today announced that the company's licensee, AnGes MG,Inc. reported positive results following interim analysis of datafrom the first 41 subjects to complete a Phase 3 trial of anangiogenesis product candidate using Vical's DNA deliverytechnology. Based on the findings that the primary efficacyendpoint in the trial had...