A gene's first 'kiss' sets off that affair known as puberty
Puberty, that awkward phase when boys and girls are primed for their sexual reproductive years as men and women, appears to be triggered by the brain's own version of "It takes two to tango," whereby a signal literally gets turned on by a molecule that is produced by a gene aptly named KiSS-1. The couple ?a biochemical equivalent to Adam and Eve ?makes its sudden appearance in a region of...Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down
For patients with high-risk breast cancer treated with radical mastectomy and adjuvant chemotherapy, the addition of radiation therapy leads to better survival outcomes with few long-term toxic effects, according to a 20-year follow-up of a randomized trial, which appears in the January 19 issue of the Journal of the National Cancer Institute. The British Columbia randomized radiation the...Genes In The Interferon System Important In Systemic Lupus Erythematosus
Two genes with very strong associations withthe disease systemic lupus erythematosus (SLE) have been identified bya team of scientists headed by researchers at the Department of MedicalSciences at Uppsala University. The findings are being published todayon the Web page of the highly prestigious American Journal of HumanGenetics. "These findings are probably the first genetic pieces of ahug...It's not all genetic: Common epigenetic problem doubles cancer risk in mice
In experiments with mice, a team of scientists from the United States, Sweden and Japan has discovered that having a double dose of one protein is sufficient to change the normal balance of cells within the lining of the colon, thereby doubling the risk that a cancer-causing genetic mutation will trigger a tumor there. Roughly 10 percent of people have this double protein dose as well. In...Columbia research lifts major hurdle to gene therapy for cancer
Researchers at Columbia University MedicalCenter have discovered a way to overcome one of the major hurdles ingene therapy for cancer: its tendency to kill normal cells in theprocess of eradicating cancer cells.In a new study published in the Jan. 25 issue of the Proceedings of theNational Academy of Sciences (PNAS), the researchers demonstrated thatthe technique works by incorporating it i...Rapid-Screen Arrayed cDNA Library Panels Master Plates -Human Placenta from OriGene Technologies
Description:The Rapid-Screen cDNA Library Panels were designed for full-length gene cloning and require just three sets of PCRs to identify the desired cDNA clone. The first PCR analysis is performed in a 96-well "Master Plate," where each well contains plasmid DNA from 5,000 clones. Having identified the positive well(s) by gel electrophoresis of the reaction products, the second PCR analysis is carried out...Rapid-Screen Arrayed cDNA Library Panels Master Plates -Human Heart from OriGene Technologies
Description:The Rapid-Screen cDNA Library Panels were designed for full-length gene cloning and require just three sets of PCRs to identify the desired cDNA clone. The first PCR analysis is performed in a 96-well "Master Plate," where each well contains plasmid DNA from 5,000 clones. Having identified the positive well(s) by gel electrophoresis of the reaction products, the second PCR analysis is carried out...Rapid-Screen Arrayed cDNA Library Panels Master Plates -Mouse Testis from OriGene Technologies
Description:The Rapid-Screen cDNA Library Panels were designed for full-length gene cloning and require just three sets of PCRs to identify the desired cDNA clone. The first PCR analysis is performed in a 96-well "Master Plate," where each well contains plasmid DNA from 5,000 clones. Having identified the positive well(s) by gel electrophoresis of the reaction products, the second PCR analysis is carried out...Low Abundance cDNA Cloned Using Stratagenes Human Universal cDNA Library
Department of Cell Biology, Clevela...New Kit Generates Exceptionally Pure Total RNA for RT-PCR
RT-PCR miniprep kit Stratagene Stratagene has determined that standard RNA purification kits are not satisfactory for reverse transcribed PCR (RT-PCR) applications. We...An Epitope Tagging Vector for Gene Expression in Mammalian Cells
Stratagene The pCMV-Tag1 vector is an epitope tagging vector designed for geneexpression in mammalian cells. A target gene inserted into the pCMV-Tag1 vectorca...Big Blue Rodent Cell Cultures for Mutagenesis Studies
Rat and mouse embryonic cell lines are useful for in vitro mutagenesisstudies Stratagene Cloning Systems, Inc. The Big Blue rat cell line and the Big Blue transgenic mouse embryoniccell line are useful for in vitro mutagenesis studies. These cell lines are partof the Big Blue transgenic rodent mutagenesis assay system...Bypass Heart Surgery Performed Without General Anesthesia
A minimally invasive direct coronary artery bypass (MIDCAB) procedure was performed at Pittsburgh while the patient was awake. The operation was done under thoracic epidural anesthesia. This approach may help in discharging the patient early from the hospital. Dr. Zenati from the team of doctors who performed the surgery said that patients who are operated in this way may not have to go t...PRIMARY PULMONARY HYPERTENSION GENE DISCOVERED
The discovery of the gene associated with the inherited form of primary pulmonary hypertension (PPH) by Drs. Jane H. Morse of Columbia University and James A. Knowles of the Columbia Genome Center is indeed a major breakthrough. Their study, funded in part by the National Heart, Lung, and Blood Institute at the National Institutes of Health and published in the September issue of th...Blood Cells Capable of Regenerating Liver
Livers can be regenerated using stem cells from blood -- an important discovery that means patients may be able to grow their own liver transplants using bone marrow. This adds to a growing body of evidence that stem cells, known as "master cells" because they can produce a variety of different kinds of cells, might one day be manipulated to create custom-grown organ transplants....Potential New Cancer Gene Identified
A Johns Hopkins University research team has discovered a new family of genes that contributes to the process of malignancy, shedding new light on the abnormalities that give rise to the aggressive childhood cancer, Burkitt's lymphoma - as well as lymphoma, leukemia, prostate, ovarian, lung, and breast cancer. Characterized by rapidly growing abdominal tumors, Burkitt's lymp...Genetic Dentistry: Your Dentist may be able to grow you a new set of Teeth.
Researchers at the University of Texas Health Science Center at San Antonio have successfully regrown mouse teeth in a petri dish from single mouse cells - and they think humans are next. They hope to push the research in the direction where they could take initial tissue from a [human] patient, put it in a culture dish and grow a tooth for them.To accomplish this seemingly futuristic fea...IDS-200 Electrosurgical Generator
Description:The Bovie IDS Series are the latest electrosurgical generators with fully digital implementation....Force EZ Electrosurgical Generator
Description:Microprocessor-based isolated electrosurgical generator, designed for all general surgical procedures. Unit includes the Valleylab adaptive REM system and Instant Response technology....Surgistat Electrosurgical Generator
Description:The Valleylab Surgistat II generator provides exceptional performance, reliability, and safety benefits in a compact, easy to use unit....Genetic Analysis Systems Enter the Clinical Mainstream
Like many other diagnostic regimes that were previously restricted to large specialty laboratories, genetic analysis is entering the clinical mainstream. Smaller, simpler analyzer systems are now suitable and affordable for hospital or large physicians group labs, while some genetic test kits are becoming available for primary point of care locations such as clinics and physician offices.<...Gene Chips to Detect CYP Variations: A New Step Toward Customized Medical Therapy.
The FDA approval of BiDil for heart failure in African American patients has underscored the concept that two patients can respond differently to the same medication. This concept holds true for a wide variety of everyday medications, and in many cases is due to individual gen...