A gene's first 'kiss' sets off that affair known as puberty
Puberty, that awkward phase when boys and girls are primed for their sexual reproductive years as men and women, appears to be triggered by the brain's own version of "It takes two to tango," whereby a signal literally gets turned on by a molecule that is produced by a gene aptly named KiSS-1. The couple ?a biochemical equivalent to Adam and Eve ?makes its sudden appearance in a region of...Man and mouse share genome structures
In the most detailed large-scale study to date of the proteins that package DNA, researchers have mapped a family of switches that turn genes on and off. Their findings may help scientists understand regulatory mechanisms underlying cancer and human development. The research team includes first author Bradley Bernstein, recipient of a Howard Hughes Medical Institute (HHMI) physician postd...Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down
For patients with high-risk breast cancer treated with radical mastectomy and adjuvant chemotherapy, the addition of radiation therapy leads to better survival outcomes with few long-term toxic effects, according to a 20-year follow-up of a randomized trial, which appears in the January 19 issue of the Journal of the National Cancer Institute. The British Columbia randomized radiation the...Genes In The Interferon System Important In Systemic Lupus Erythematosus
Two genes with very strong associations withthe disease systemic lupus erythematosus (SLE) have been identified bya team of scientists headed by researchers at the Department of MedicalSciences at Uppsala University. The findings are being published todayon the Web page of the highly prestigious American Journal of HumanGenetics. "These findings are probably the first genetic pieces of ahug...Yellowstone microbes fueled by hydrogen, according to U. of Colorado study
Microbes living in the brilliantly coloredhot springs of Yellowstone National Park use primarily hydrogen forfuel, a discovery University of Colorado at Boulder researchers saybodes well for life in extreme environments on other planets and couldadd to understanding of bacteria inside the human body.A team of CU-Boulder biologists led by Professor Norman Pace, one ofthe world's leading expe...Blasticidin S HCl from Invitrogen
Description:Blasticidin is a nucleoside antibiotic from Streptomyces griseochromogenes. It is a potent translational inhibitor in both prokaryotic and eukaryotic cells. Resistance to blasticidin is conferred by the products of the bsd gene product from Aspergillus terreus....EBY100 S. cerevisiae Strain from Invitrogen
Description:The pYD1 Yeast Display Vector is specifically designed to target and display recombinant proteins on the surface of Saccharomyces cerevisiae. Displayed proteins can be analyzed for their ability to interact with known or putative ligands. pYD1 uses the a-agglutinin yeast adhesion receptor which consists of two domains Aga1 and Aga2 to display recombinant protein on the surface of S. cerevisiae. T...S-Protein Agarose from Novagen
Description:...Baker's yeast (S. cerevisiae) Hexokinase and glucose-6-phosphate dehydrogenase from Sigma-Aldrich
Description:Useful for determination of glucose and ATP. -glucose per min at pH 7.6 at 25C....STag Thrombin Purification Kit from Novagen
Description:Request Info...Low Abundance cDNA Cloned Using Stratagenes Human Universal cDNA Library
Department of Cell Biology, Clevela...New Kit Generates Exceptionally Pure Total RNA for RT-PCR
RT-PCR miniprep kit Stratagene Stratagene has determined that standard RNA purification kits are not satisfactory for reverse transcribed PCR (RT-PCR) applications. We...An Epitope Tagging Vector for Gene Expression in Mammalian Cells
Stratagene The pCMV-Tag1 vector is an epitope tagging vector designed for geneexpression in mammalian cells. A target gene inserted into the pCMV-Tag1 vectorca...Big Blue Rodent Cell Cultures for Mutagenesis Studies
Rat and mouse embryonic cell lines are useful for in vitro mutagenesisstudies Stratagene Cloning Systems, Inc. The Big Blue rat cell line and the Big Blue transgenic mouse embryoniccell line are useful for in vitro mutagenesis studies. These cell lines are partof the Big Blue transgenic rodent mutagenesis assay system...Human Genome Project Achieves Technological Triumph
The completion of rough draft sequence of the human genes is a major scientific milestone and was achieved on 26.06.2000. The project began more than 10 years ago to map out almost 35 billion chemical letters that make up the recipe of human life. This breakthrough is expected to revolutionize the practice of medicine by paving the way for new drugs and medical therapies.Specific sequ...Bypass Heart Surgery Performed Without General Anesthesia
A minimally invasive direct coronary artery bypass (MIDCAB) procedure was performed at Pittsburgh while the patient was awake. The operation was done under thoracic epidural anesthesia. This approach may help in discharging the patient early from the hospital. Dr. Zenati from the team of doctors who performed the surgery said that patients who are operated in this way may not have to go t...PRIMARY PULMONARY HYPERTENSION GENE DISCOVERED
The discovery of the gene associated with the inherited form of primary pulmonary hypertension (PPH) by Drs. Jane H. Morse of Columbia University and James A. Knowles of the Columbia Genome Center is indeed a major breakthrough. Their study, funded in part by the National Heart, Lung, and Blood Institute at the National Institutes of Health and published in the September issue of th...Blood Cells Capable of Regenerating Liver
Livers can be regenerated using stem cells from blood -- an important discovery that means patients may be able to grow their own liver transplants using bone marrow. This adds to a growing body of evidence that stem cells, known as "master cells" because they can produce a variety of different kinds of cells, might one day be manipulated to create custom-grown organ transplants....Potential New Cancer Gene Identified
A Johns Hopkins University research team has discovered a new family of genes that contributes to the process of malignancy, shedding new light on the abnormalities that give rise to the aggressive childhood cancer, Burkitt's lymphoma - as well as lymphoma, leukemia, prostate, ovarian, lung, and breast cancer. Characterized by rapidly growing abdominal tumors, Burkitt's lymp...3.5v Halogen HPX Spot Retinoscope
Description:3.5v Halogen HPX Spot Retinoscope provides 40% more light output than conventional scopes and maintains a consistent output level which greatly enhances illumination and produces the sharpest retinal reflex, making refractions....3.5v Halogen HPX Streak Retinoscope
Description:3.5v Halogen HPX Streak Retinoscope comes with a lithium-ion handle and provides 40% more light output than conventional scopes and maintains a consistent output level which greatly enhances illumination and produces the sharpest retinal reflex, making refractions....Fast, Accurate Influenza A/B Antigen Detection
According to CDC data, influenza infections in this country cause more than 114,000 hospitalizations and 36,000 deaths annually. Among healthy adults, bronchitis and pneumonia are the most common complications. Together, influenza and pneumonia are the sixth leading cause of death in the United States. Influenza is particularly dangerous in elderly and immunocompromised people; however, infec...Monitoring Options Expand for Therapeutic Agents and Drugs of Abuse
In keeping with the recent proliferation of rapid, easy-to-use diagnostic tests, many assays and collection products have entered the marketplace to help clinicians assess dosage appropriateness of therapeutic drugs and to screen for the presence of drugs of abuse. Some of these products require laboratory support while many simple test kits are suitable for point of care use by medical profe...Genetic Analysis Systems Enter the Clinical Mainstream
Like many other diagnostic regimes that were previously restricted to large specialty laboratories, genetic analysis is entering the clinical mainstream. Smaller, simpler analyzer systems are now suitable and affordable for hospital or large physicians group labs, while some genetic test kits are becoming available for primary point of care locations such as clinics and physician offices.<...Gene Chips to Detect CYP Variations: A New Step Toward Customized Medical Therapy.
The FDA approval of BiDil for heart failure in African American patients has underscored the concept that two patients can respond differently to the same medication. This concept holds true for a wide variety of everyday medications, and in many cases is due to individual gen...