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fragments in Medical News

Parasites a key to the decline of red colobus monkeys in forest fragments

Forest fragmentation threatens biodiversity, often causing declines or local extinctions in a majority of species while enhancing the prospects of a few. A new study from the University of Illinois shows that parasites can play a pivotal role in the decline of species in fragmented forests. This i...

Protein Fragments Blocking Cures Alzheimer's Disease

Professor Yadong Huang and his team from Gladstone Institute of Neurological Disease have found that the protein apolipoprotein E (apoE) is responsible for causing Alzheimer's disease //that acts by inactivating the conversion of glucose into energy in Mitochondirial cells due to the protein fragme...

Infertility may result from bone fragments

According to a report infertility in healthy women may sometimes be caused by the presence of fetal bone fragments left embedded in the uterus after a previous abortion. There were evidence over the years that small pieces of fetal bone left behind after abortion cause chronic irritation which coul...

GenVault's GenSolve(TM) Reagents Enable State-of-the-Art Genomic Analysis of Dried Blood Spots

...roarray analysis and SNP genotyping studies. Previously reported methods for recovery of DNA from blood dried on Guthrie cards and FTA paper generated fragments of single stranded, denatured DNA which were unsuitable for such analyses. "What is exciting about the observations made in these publications ...

Music Had Charms to Soothe Prehistoric Man

...000 years ago and were found in France and Austria. Last summer, however, the German paleontologists found a nearly complete flute made of bone and fragments of three ivory flutes. Just like modern flutes, the ancient ones have holes that humans could cover to make different sounds when blowing through them...

Hysterectomies Could Be Source of Stem Cells

...mbilical cords, dental pulp and body fat. Together, these findings are of great interest, the researchers said. "Moreover, the use of human tissue fragments that are usually discarded in surgical procedures does not pose ethical problems," Jazedje said. More information The U.S. National Institutes...
fragments in Medical Technology

Myelin Removal Beads: Premium Efficiency for Neural Cell Separations and Antibody Stainings

...vous system. During preparation of single-cell suspensions, myelin membrane fragments represent the major contaminant. "When dissociating adult neural tissue, us...th other MACS Technology products", adds Dr. Biloune. "Contaminating myelin fragments can be depleted either by manual protocols or by automated magnetic separat...

Raptor Pharmaceuticals Receives Notices of Allowance for Two NeuroTrans(TM) Patent Applications

...812,849 and 11/202,566, titled " Methods of increasing delivery of active agents to brain comprising administering receptor-associated protein ("RAP") fragments conjugated to active agents ." (Logo: http://www.newscom.com/cgi-bin/prnh/20071022/NYM074LOGO ) The newly allowed claims relate to Raptor's...

ESBATech's Antibody Fragment Enters Phase Ib/IIa in Ophthalmology

...asic feasibility of applying single-chain antibody fragments to the eye. With ESBA105, the people from ESBATech... therapeutic concentrations of ESBATech's antibody fragments with eye drops represents a major step forward in ...oach to stabilize monomeric, single-chain antibody fragments (scFvs) using its proprietary fully-human antibody...

ESBATech's Antibody Fragment Enters Phase I/IIa Clinical Development in Osteoarthritis with the Potential for Disease-Modifying Activity

...nical Development at ESBATech AG, added, "Antibody fragments have a number of advantages over whole antibodies,...oach to stabilize monomeric, single-chain antibody fragments (scFvs) using its proprietary fully-human antibody... development company focused on advancing antibody fragments for therapeutic applications. The Company applies ...

AFFiRiS Begins Development of a Parkinson's Vaccine

... developing two vaccines and a hemodialysis program for the treatment of Alzheimer's. These therapies only target specific structures found on harmful fragments of beta-amyloid, which is said to be responsible for Alzheimer's. Both Alzheimer's vaccines are currently being trialled on Alzheimer patients. In Oct...

Dronedarone (Multaq(R)) Reduced the Incidence and Duration of Hospitalization in Patients with Atrial Fibrillation

...t for patients with AF are related to managing the arrhythmia itself and to the prevention of thromboembolism (obstruction of a blood vessel caused by fragments of a blood clot carried from the site of origin to obstruct another vessel). Atrial fibrillation may be treated with medications which either slow the...
fragments in Medical Products

Triad Plus PVP-I Prep Swabsticks

Description:...in or natural fabrics. Our swabsticks not only kill microbes on contact; they are sturdy tools for removing small particles from wounds, such as glass fragments and gravel....
Company:Triad Group, Inc.

Alio-Prats Irrigating "Stinger"

Description:...asy insertion through a micro incision and a short, "stinger" tip for dividing and chopping the nucleus. In addition, the tip is ideal for retrieving fragments from underneath the iris which can be located peripherally inside the capsular bag. The large irrigation port is directed toward the posterior capsul...
Company:Katena Products, Inc.

Wide Mini Horizontal Gel System

Description:... Wide mini horizontal gel system is designed for very fast and clear separation of DNA restriction fragments in agarose gels. This System allows the user to cast, run, and perform Southern or Northern blotting of high quality. Complete system with : 1 x elect...
Company:Major Science

Shorter Mini Horizontal Gel Electrophoresis System

Description:... Shorter mini horizontal gel electrophoresis system is designed for very fast and clear separation of DNA restriction fragments in agarose gels. This system allows the user to fast cast, run and perform Southern or Northern blotting of high quality. Complete system with : 1 x e...
Company:Major Science

HE 33 Mini Submarine unit, Complete

Description:...fers the HE 33 Mini Submarine Unit for nucleic acid analysis in the mini gel range. The HE 33 is designed for very fast separations of DNA restriction fragments in agarose gels. The clear molded base acts as a heat-sink. Fill the base with coolant and seal. Precool the unit prior to the run, by either keeping ...
Company:Hoefer, Inc.

HE 33 Mini Submarine unit, Basic

Description:...fers the HE 33 Mini Submarine Unit for nucleic acid analysis in the mini gel range. The HE 33 is designed for very fast separations of DNA restriction fragments in agarose gels. The clear molded base acts as a heat-sink. Fill the base with coolant and seal. Precool the unit prior to the run, by either keeping ...
Company:Hoefer, Inc.
fragments in Medical Definition

Thymocyte

...ng enzymes to clip the DNA and bring separate gene fragments together. The outcome of this process is that each...ifferent sequence, due to different choice of gene fragments and the errors introduced during the cutting and j... of the combinations of the T cell receptor gene fragments are non-functional. To eliminate thymocytes which ...
fragments in Medical Dictionary

Thrombocytopenia

... galleries - updated 24/7... Thrombocytopenia (THROM-bo-si-to-PE-ne-ah ) is a condition in which your blood has a low number of blood cell fragments called platelets (PLATE-lets) The condition can be inherited (passed from parents to children), or it can develop at any age. ... of factors can c...

Rectal biopsy

...al biopsy . Rectal biopsy ... On microscopic examination of biopsy tissue, no abnormalities should be noted. ... Pathology showed multiple fragments of rectal mucosa heavily infiltrated by a ... Careful EUA and random rectal biopsy may be indicated in all patients with acute ... Rect...

Platelet

...in blood. ... The platelets sense the presence of air and begin to break apart. ... Platelets , also called thrombocytes (THROM-boh-sites), are fragments of bone ... A low platelet count is referred to as thrombocytopenia. ... Platelet transfusions are traditionally given to those undergoing ch...

Metabolize

...etabolism metabolize synonyms. metabolize usage examples and metabolize quotes. ... drug: One species may metabolize a drug into toxic fragments whereas another may ... Shop for Metabolize in the Health section of Shop.com. Thousands of Brands. Hundreds of Stores. metabolize . Defini...

Knee arthroscopy

... Knee Arthroscopy . Arthroscopy has revolutionized the treatment of knee injuries. ... Arthroscopy ... By flushing the knee free of loose fragments of cartilage ... Knee arthroscopy is a minimally invasive technique that allows orthopaedic ... instrumentation, use of arthroscopy , par...

Fractures

... Fractures of the small wrist bones, such as the scaphoid, are unlikely to appear ... Other fractures are unstable, which implies that the bone fragments tend to ... ...
fragments in Biological News

Fossil fragments reveal 500-million-year-old monster predator

Hurdia victoria was originally described in 1912 as a crustacean-like animal. Now, researchers from Uppsala University and colleagues reveal it to be just one part of a complex and remarkable new animal that has an important story to tell about the origin of the largest group of living animals, ...

Protein fragments sequenced in 68 million-year-old Tyrannosaurus rex

In a venture once thought to lie outside the reach of science, researchers from Harvard Medical School and Beth Israel Deaconess Medical Center have captured and sequenced tiny pieces of collagen protein from a 68 million-year-old Tyrannosaurus rex. The protein fragments—seven in all—appear to most...

University of Toronto helps to 'barcode' the world's plants

...ganisms, poisonous species and fragmentary material in forensic investigations. The technique will work on minute amounts of tissue and can be used on fragments of plant material, small seedlings, and in some cases digested or processed samples. The methodology will also be used immediately in global projec...

The right messenger for a healthy immune response

...HZI have now managed to show why this is the case: Beta-Interferon is a key regulator and of vital importance in enabling the immune system to display fragments of pathogens, so-called antigens. Immune cells present these antigens on their surface and in this way communicate with one another: antigens are the ...

Telomeres resemble DNA fragile sites

...on fragile sites, suggesting that TRF1 protects telomeres from becoming fragile. Instead of a continuous string of DNA, the telomeres were broken into fragments of twos and threes. To see if the replication fork stalls at telomeres, de Lange and Sfeir joined forces with Carl L. Schildkraut, a researcher at Alb...

The tiny difference in the genes of bacteria

...with certain dyes. Each dyed DNA fragment recognizes a single tandem repeat, binding at it. As a result, the researchers receive, for example, six red fragments binding a tandem of six repetitions. Then, the researchers analyzed the tandem repeats marked with dyed fragments: Every bacteria strain differs in pa...
fragments in Biological Technology

Frost & Sullivan Recognizes ESBATech's Innovation in Developing Antibody Fragments for Biologic Therapeutics

MOUNTAIN VIEW, Calif., Jan. 26 /PRNewswire/ -- Based on its recent analysis of the ophthalmic pharmaceuticals market, Frost & Sullivan recognizes ESBATech with the 2009 North American Frost & Sullivan Technology Innovation of the Year Award for its work in developing antibody fragments. Th...

ESBATech's Antibody Fragments Demonstrate Penetration into the Eye with Topical Delivery via Eye Drops

Preclinical results to be presented at two international scientific meetings ZURICH, Switzerland, Feb. 25 /PRNewswire/ -- ESBATech AG, a leading developer of antibody fragment therapeutics, today announced that it has achieved high concentrations of its antibod...

Resolution of Linear DNA Fragments From 23 Kilobases to 6 Megabases Using Biphasic Linear Switch-Time Ramping

Contributed by Donald R. VanDevanter, Tumor Institute, Swedish Hospital Medical Center, 409 Elkind Hall, 747 Summit Avenue, Seattle, WA 98104 Introduction Analyses of uncharacterized DNA fragments using CHEF electrophoresis often req...

Fractionating DNA Fragments Generated by Differential Display PCR

CastAway system application Iain Kilty Phil Vickers Pfizer Central Research, Sandwich, UK. 01304 618482 Differential display PCR (DDPCR) is a widely used technique for identifying genes differentially expressed between cell types. Application of DDPCR to allergic disease provides a...

Court bars patent protection for certain gene fragments

The Court of Appeals for the Federal Circuit (CAFC) issued a patent-law decision last month that inevitably will render hundreds of pending patent applications worthless, and that will raise the bar for proving gene and protein related inventions useful. At issue was whether certain gene frag...

Efficient Cloning and Electro-transformation of Large Eukaryotic DNA Fragments

Contributed by John M. Sedivy, Department of Molecular Biophysics and Biochemistry, Yale University, 333 Cedar Street, New Haven, CT 06510. Introduction Genes of higher eukaryotes can be hundreds of kilobases in size. The need to rapid...
fragments in Biological Products

Sheep Anti-Digoxigenin Fab fragments Antibody, AP Conjugated from Roche Applied Science

Description: Anti-Digoxigenin-AP, Fab fragments; from sheep...
Company:Roche Applied Science

6X DNA Loading Buffer from Novagen

Description:... 6X Loading Buffer is intended for gel electrophoresis of DNA fragments or PCR products....
Company:Novagen

6X DNA Gel Loading Buffer from Novagen

Description:... 6X DNA Gel Loading Buffer is intended for gel electrophoresis of DNA fragments or PCR products....
Company:Novagen

Anti-J Chain Monoclonal Antibody, Unconjugated, Clone M19/9J from CHEMICON

Description:... This antibody is specific for human J-chain as defined by ELISA assay using purified human immunoglobulin fragments as solid phase target antigen....
Company:CHEMICON

DNA Fragment 2X Precipitation Solution from EPICENTRE Biotechnologies

Description:... Enables rapid purification of double-stranded DNA fragments = 200 bp, including, for example, PCR reaction products, DNA fragments obtained in restriction enzyme digests, or double-stranded cDNA...
Company:EPICENTRE Biotechnologies

RNase III, E. coli from EPICENTRE Biotechnologies

Description:...ribonuclease that specifically digests double-stranded RNA (dsRNA) to dsRNA fragments that have 2-base, 3'-overhangs. Complete digestion of dsRNA results in dsRNA fragments of 12-15 bp. RNase III can digest double-stranded RNA composed of canonica...
Company:EPICENTRE Biotechnologies
fragments in Biological Definition

Antibody

...ght constant domains and four variable domains. If it is cleaved with enzymes papain and pepsin , we get two Fab ( f ragment b inding a ntigen) fragments and an Fc ( f ragment c rystallizable) fragment. Each half of the forked end of the "Y" shaped monomer is called the Fab fragment. It is composed...

Antigen

...ng cells (APCs), and degraded into fragments. The fragments are then presented on the surface of APCs by clas... viral or intracellular bacterial infection . The fragments are then presented on the cell surface in the comp...those CTL that do not react to normal body protein fragments are allowed to enter the bloodstream. ...

Apoptosis

...fit, like a key and a lock, with specialized receptors in B and T cell membranes). For instance, "killer" T cells can be activated when presented with fragments of inappropriately expressed proteins (resulting, say, from a malignant mutation) or with foreign antigen produced as a consequence of a viral infecti...

Sticky end/blunt end

... CpApTpApCpGpA -5' becomes 5'- ApTpCpTpGpApCpT pGpApTpGpCpGpTpApTpGpCpT -3' 3'- TpApGpApCpTpGpApCpTpApCpGp CpApTpApCpGpA -5' The two fragments may then be covalently bonded by DNA ligase . Blunt ends may be ligated, but the reaction is significantly slower. These terms are most commonly us...

Bioinformatics

...ut instead the sequences of thousands of small DNA fragments (each about 600 nucleotides long). The ends of these fragments overlap and, aligned in the right way, make up the...equence data quickly, but the task to re-align the fragments can be quite complicated for larger genomes. In th...

Bioinformatics

...ut instead the sequences of thousands of small DNA fragments (each about 600 nucleotides long). The ends of these fragments overlap and, aligned in the right way, make up the...equence data quickly, but the task to re-align the fragments can be quite complicated for larger genomes. In th...
fragments in Biological Dictionary

Okazaki fragments

An Okazaki fragment is a relatively short fragment of DNA created on the lagging strand during DNA replication. The lengths of Okazaki fragments are between 1,000 to 2,000 nucleotides long in E. coli and are generally between 100 to 200 nucleotides long in eukaryotes.... Okazaki fra...

VNTR

...NTR locus, a number of different alleles may exist, each with ... If the fragments of DNA containing the VNTR alleles are to be separated on the ... V...at YELLOWPAGES.COM By using buoyant density gradient centrifugation, DNA fragments with ... One type of minisatellites is called variable number of tandem re...

Transposase

...has the D-D-E motif and thus ... Tn5 transposase is the key enzyme in forming transposomes for random transposon insertions. ... of cut out fragments with transposase molar excess of 0-9x ... ... tnpR, this transposon also carries a transposase or tnpA and a β-lactamase Bla ... This process...

Thallus

...istorian who wrote in Greek. It is uncertain when he wrote, but it was probably in the middle of the first century . His works are all lost, but a few fragments have reached us in later Ancient and Medieval writers. The most interesting of these is a... thallus n. , pl. thalli or -luses . A plant body...

Thrombocytes

... Thrombocytes are cells that play a key role in blood clotting. In mammals, thrombocytes are anucleated cell fragments called platelets. Nucleated thrombocytes of nonmammalian vertebrates differ from the mammalian thrombocytes not only in having a nucleus and t...

Sub-cloning

... in E. coli. 1. Sub - cloning . ... PLoS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC ... Sub - cloning vector-derived fragments requires the donor fragment to be excised ... China to Try Cloning of Rare Monkeys - Using advanced technology to research ... Online - An online...
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