Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats
Dana-Farber Cancer Institute researchers have identified a molecular mechanism in the liver that explains, for the first time, how consuming foods rich in saturated fats and trans-fatty acids causes elevated blood levels of cholesterol and triglycerides and increases one's risk of heart disease and certain cancers. In the Jan. 28 issue of Cell, scientists led by Bruce Spiegelman, PhD, rep...Lack of enzyme turns fat cells into fat burners
Lack of the enzyme, acetyl CoA carboxylase 2or ACC2, appears to turn the adipose or fat cells of mice into fatburners, explaining in part why the animals can eat more and weigh lessthan their normal counterparts, said Baylor College of Medicineresearchers.The report that appears online today in the Proceedings of the NationalAcademy of Sciences. "Westudied the fat cells in these mic...Newly-discovered class of genes determines ?and restricts ?stem cell fate
Research on adult stem cells found in the skin hints at a new class of genes, according to a study from investigators at the University of Pennsylvania School of Medicine. These genes ?dubbed pangenes ?can both govern a stem cell's fate and put a hold on future differentiation until the time is right. Understanding the molecular control of these genes has implications for therapies that involve t...Tiny scaffolding allows stem cells to become working fat cells
Researchers here have used a new microscopic, three-dimensional scaffolding to coax mouse stem cells to transform themselves into fat cells, and then to function identical to how fat cells naturally do in the body. While other studies have previously grown fat cells, or adipocytes, in the laboratory, those cells never completely functioned in the same way they do in normal tissue. They fai...Opposing fat metabolism pathways triggered by a single gene
Regulating metabolism of fat is an important challenge for any animal, from nematodes to humans. Central players in the regulatory network are the nuclear hormone receptors (NHRs), which are transcription factors that turn on or off a set of target genes when bound by specific lipid molecules. In the premier open-access journal PLoS Biology, Keith Yamamoto and colleagues show that the nuclear hor...Bleomycin sulfate, Unconjugated from USB Corp.
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Description:Kanamycin is used for selection of resistant bacteria. C18H36N4O11xH2SO4. Contains 10 mg/ml kanamycin (base) utilizing kanamycin sulfate in 0.85% saline....QBT Fatty Acid Uptake Assay Kit datasheet
NO RADIOACTIVITY NO WASH STEPS EASY SINGLE-STEP ASSAY HTS READY FATTY ACID UPTAKE AND TRANSPORTERS Fatty acids are utilized for diverse cellularprocesses including mitochondria oxidation,membrane synthesis and energy...Father of life patents downplays historic role
Chakrabarty, the first person to successfully patent life forms, visited Wisconsin this we...Steroid Treatment after head injury may be fatal
According to a report from Lancet, Patients with head injury who were treated with methylprednisolone had a significantly increased risk of death within //the following 2 weeks compared with untreated group of patients. "Our early results show that corticosteroids should not be used routinely to treat head injury, whatever the severity," Dr. Ian Roberts. He is clinical coordinator of...A Sedentary Childhood Could Lead To Chronic Fatigue Latter In Life
Chronic fatigue syndrome is an often disabling condition that affects primarily women. The condition is characterized by deep-seated fatigue // that cannot be overcome with rest and often worsens with physical activity. The cause of the condition is unknown, and there are no diagnostic tests or cures. A recent study explains that children who have sedentary behaviors are at increased risk...Canadians Grow Fatter By The Day
Canadians are becoming increasingly obese, according to a new study. The number of people in the country who are morbidly obese has risen to 1.3% in 2003, from the 1990 figure of 0.3%, according to researchers belonging to Queen's University. //The body mass index (BMI) is made use of by Health Canada for measuring obesity, and if the BMI is above 25, a person is declared overweight, and...Role of fats and oils in vision care
The balance of fats and oils in your diet can affect your vision, according to a new study. Age-related macular degeneration (AMD) is a currently untreatable disease of the eye causing fuzziness, shadows and severe visual impairment. As the name suggests, it gets worse with age and diet has been implicated in its development. // Researchers at the Massachusetts Eye and Ear Infirmary c...Omega-3 fatty acids impair immunity
Taking large amounts of omega-3 fatty acids may be unwise for those with weakened immunity.Researchers at the University of Missouri, Columbia, have been studying omega-3s for many years now and know that one of their effects is to damp down inflammation. That's why fish oils - rich in omega-3s - often benefit those with arthritis, a painful inflammatory condition of the joints. Yet the i...LB Agar Plates Magnesium Sulfate-10
Description:LB Agar plates with 10mM Magnesium Sulfate....Fat Kills Cancer: Turning Stem Cells from Fat Tissue into Personalized, Cancer-Targeted Therapeutics
PHILADELPHIA, July 3, 2007 ? Researchers in Slovakia havebeen able to derive mesenchymal stem cells from human adipose, orfat, tissue and engineer them into “suicide genes” that seek out and destroy tumors like tiny homing missiles. This gene therapy approach is a novel way to attack smalltumor metastases that evade current detection techniques andtreatments, the researchers...Once-Fatal Metabolic Disorders Treatable, Says Stanford/Packard Researcher
STANFORD, Calif.--(BUSINESS WIRE)--May 30, 2007 - People with aclass of rare genetic disorders that often lead to brain damage,coma and death can be successfully treated with drugs, says aresearcher at the Stanford University School of Medicine and LucilePackard Children's Hospital. The researchers found in their unprecedented 25-year study thatprompt diagnosis coupled with a rapid start...