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Factor in Medical News

FDA Approves New 3000 IU Vial Size for Kogenate(R) FS, antihemophilic factor (recombinant)

WAYNE, N.J., Aug. 7 /PRNewswire/ -- Today, Bayer HealthCare Pharmaceuticals announced that the U.S. Food and Drug Administration (FDA) has approved a 3000 IU (international unit) vial size of Kogenate(R) FS , antihemophilic factor (recombinant). The new vial size offers greater co...

Amgen and Wyeth Statement on FDA Announcement About Tumor Necrosis Factor (TNF) Blockers

THOUSAND OAKS, Calif. and COLLEGEVILLE, Pa., Aug. 4 /PRNewswire-FirstCall/ -- Amgen (Nasdaq: AMGN ) and Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE ), issued a statement in response to the Food and Drug Administration (FDA) announcement regarding the results of a safety rev...

Anti-growth factor drugs raise hope and concern for treatment of children's eye diseases

Philadelphia, PA, 3 August 2009 A new class of antibody drugs may provide a powerful new tool for the treatment of eye diseases in children, but specialists need to be alert for the possibility of serious side effects, according to an editorial in the August Journal of AAPOS (American Associati...

Study in this Week's Issue of Cell Finds Injected Growth Factor Spurs Heart Regeneration

Growth factor enhances heart regeneration, improves heart function without need for cardiac stem cells (Vocus) July 16, 2009 -- Injured heart tissue normally can't regrow, but researchers at Children's Hospital Boston have now laid the groundwork for regenerating hear...

Journal of Alzheimer's Disease once again achieves significant impact factor increase

Amsterdam, The Netherlands and San Antonio, TX, USA, July 13, 2009 International publisher IOS Press and the Editors-in-Chief of the Journal of Alzheimer's Disease (JAD) are pleased to announce that once again there has been a significant increase in the Journal's Impact Factor, from 4.081 to 5...

Analysis of Four Large Post-Marketing Surveillance Studies Describe Clinical Effects of Sucrose-Formulated Recombinant Factor VIII

BOSTON, July 13 /PRNewswire/ -- New data pooled from four large, "real world" post-marketing surveillance studies showed that sucrose-formulated recombinant factor VIII (rFVIII-FS) reduced bleeding and provided data regarding adverse events in more than 950 patients with mild-to-severe hemophilia ...

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Factor in Medical Technology

deCODE Discovers Second Common Genetic Risk Factor for Atrial Fibrillation and Stroke

REYKJAVIK, Iceland, July 13 /PRNewswire-FirstCall/ -- Scientists at deCODE genetics (Nasdaq: DCGN ) and colleagues from Europe and the United States today report the discovery of a common single-letter variant in the sequence of the human genome (SNP) conferring increased risk of atrial fibr...

Scientists Discover a Role for the Growth Factor TGF-beta in Maintaining Health of Retinal Blood Vessels

BOSTON, April 7 /PRNewswire-USNewswire/ -- Scientists at Schepens Eye Research Institute have found that the growth factor known as TGF-beta is essential to the health of blood vessels in the retina and that blocking it can cause retinal dysfunction. These findings, published in the April 2 is...

New Research Suggests Platelet 'Stickiness' May be the Single Most Important Risk Factor in Patients Treated with Coronary Stents - Findings May be Applicable to Anyone with Vascular Disease

BALTIMORE, Jan. 27 /PRNewswire/ -- Most Americans know their cholesterol level, but do they know how "sticky" their platelets are? Research findings from Dr. Paul A. Gurbel, an interventional cardiologist and Director of the Sinai Center for Thrombosis Research based at Sinai Hospital of Baltimor...

New Phase II Data Show Safety of Once-Daily Oral Factor Xa Inhibitor, DU-176b, Comparable to Warfarin in Patients With Non-Valvular Atrial Fibrillation

SAN FRANCISCO, Dec. 7 /PRNewswire-FirstCall/ -- Patients with non-valvular atrial fibrillation receiving either 30 mg or 60 mg once-daily dose of DU-176b, an investigational oral Factor Xa inhibitor, experienced comparable safety and tolerability compared to those taking warfarin, according to new...

Daiichi Sankyo Initiates Phase III Trial of Its Investigational Factor Xa Inhibitor, DU-176b, in Patients With Atrial Fibrillation

TOKYO and EDISON, N.J., Dec. 7 /PRNewswire-FirstCall/ -- Daiichi Sankyo Company, Limited (TSE: 4568), announced today that it has initiated its pivotal Phase III trial for DU-176b, an investigational oral Factor Xa inhibitor, in patients with atrial fibrillation. DU-176b is being developed solely...

Pharmacyclics Announces Completion of Phase 1 Clinical Trial of Factor VIIa Inhibitor PCI-27483

SUNNYVALE, Calif., Nov. 25 /PRNewswire-FirstCall/ -- Pharmacyclics, Inc. (Nasdaq: PCYC ) today announced that the company has completed a Phase 1 clinical trial with PCI-27483, the company's novel, first-in-class small-molecule Factor VIIa inhibitor. The trial was conducted in sixteen (16) healt...

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Factor in Medical Products

Pefakit Factor XIII Combi Pak

Description: Quantitative Plasma-based Factor XIII Incorporation Assay Kit...
Company:Centerchem, Inc.

Pefakit Factor XIII

Description: Quantitative Plasma-based Factor XIII Incorporation Assay Kit...
Company:Centerchem, Inc.

Pefakit APC-R Factor V Leiden Control

Description: Controls for APC Resistance / Factor V Leiden Functional Assay...
Company:Centerchem, Inc.

von Willebrand Factor Antigen

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

von Willebrand Factor Activity (Ristocetin Cofactor)

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Thrombotic Risk, Inherited Etiologies (Most Common) with Reflex to Factor V Leiden

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

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Factor in Medical Definition

Cachexia

...e is probably a role for inflammatory cytokines such as tumor necrosis factor alpha (TNF-α) -which is also nicknamed cachexin for this reason-, Inter...terleukin 6 (IL-6), as well as the tumor secreted proteolysis inducing factor (PIF). Related malnutrition syndromes are kwashiorkor and marasmus , a...

Central tolerance

...eral sites. In the case of T cell central tolerance, additional sources of antigen are made available in the thymus by the action of the transcription factor AIRE . After exposure to self antigens, T cells and B cells become immunologically tolerant (non-reactive) in a number of ways : Negative sele...

Medicine

...sal health care might allow or ban a parallel private market. The latter is described as single-payer system. Transparency of information is another factor defining a delivery system. Access to information on conditions, treatments, quality and pricing greatly affects the choice by patients / consumers an...

High Frequency Ventilation

...fectively by using negative pressure in the thorax . Once positive pressure is applied, some degree of VILI is likely to occur. One major causative factor is the over stretching of the airways and alveoli . During mechanical ventilation, the flow of gas into the lung will take the path of least resistan...

Patient trade-off

... Access to valid empirical information is crucial for such decision making. However the individual’s feeling towards the subject in question is also a factor based on emotional values and theological positions rather than knowledge. An individual that does not care about a certain documented side effect of ...

Proteopathy

...loid β peptide (Aβ) Cataracts Crystallins Medullary thyroid carcinoma Calcitonin Cardiac atrial amyloidosis Atrial natriuretic factor Pituitary prolactinoma Prolactin Hereditary lattice corneal dystrophy Keratoepithelin Cutaneous lichen amyloidosis Keratins ...
Factor in Medical Dictionary

Rheumatoid factor

Rheumatoid factor (RF or RhF) is an autoantibody most relevant in rheumatoid arthritis. It is an antibody against the Fc portion of IgG, which is itself an antibody. RF and IgG join to form immune complexes which contribute to the disease process. Not all people with... Describes when...

Rh factor

The term Rhesus ( Rh ) blood group system refers to the 5 main Rhesus antigens as well as the many other less frequent Rhesus antigens. The terms Rhesus factor and Rh factor are equivalent and refer to the Rh D antigen only. If you just found out you're pregnant, one of the first te...

Intrinsic factor

Intrinsic factor is a glycoprotein produced by the parietal cells of the stomach. It is necessary for the absorption of vitamin B12 later on in the terminal ileum. intrinsic factor n. A substance that is secreted by the gastric mucous membrane and is essential for the absorption ...

Zinc in diet

... tend to be low in zinc . ... ... Healthopedia.com > Medical Encyclopedia > Diet and Nutrition > Zinc in the Diet ... Another factor is not getting enough zinc in the diet . ... ...

Vitamin B12

...een considerable research into proposed plant sources of vitamin B12 . ... Selective impaired absorption of vitamin B12 due to intrinsic factor deficiency. ... Vitamin B12 enhances the phase-response of circadian melatonin rhythm to a ... Recipes, nutrition and food guidelines...

Uric acid

...is called hyperuricemia. ... Experimental Evidence: Nearly 120 years have elapsed since serum uric acid was first described as a potential factor in the development of cardiovascular disease. In the joints, these uric acid crystals cause inflammatory arthritis, which in ... Chalky depo...

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Factor in Biological News

UAB study reveals bone coupling factor key to skeletal health

BIRMINGHAM, Ala. Researchers at the University of Alabama at Birmingham (UAB) have discovered a molecular coupling factor that helps bones grow and remodel themselves to stay strong, a finding that could lead to better bone-building therapies and new osteoporosis drugs, the researchers said Th...

Neural stem cell differentiation factor discovered

Neural stem cells represent the cellular backup of our brain. These cells are capable of self-renewal to form new stem cells or differentiate into neurons, astrocytes or oligodendrocytes. Astrocytes have supportive functions in the environment of neurons, while oligodendrocytes form the myelin lay...

Elsevier announces 2008 journal impact factor highlights

Amsterdam, 29 June 2009 Elsevier, the leading publisher of scientific, technical and medical information products and services, today announced the highlights of its journal impact factor performance in 2008. Elsevier overall saw 75% of its journal impact factors (IF) increase from 2007 to 2008. ...

In the warming West, climate most significant factor in fanning wildfires' flames

The recent increase in area burned by wildfires in the Western United States is a product not of higher temperatures or longer fire seasons alone, but a complex relationship between climate and fuels that varies among different ecosystems, according to a study conducted by U.S. Forest Service and ...

Impact Factor names Cell top research journal

CAMBRIDGE, Mass., USA (June 23, 2009) For the second year in a row, Cell is ranked cell biology's top research journal, according to new data released in the 2008 Journal Citation Reports published by ThomsonReuters. In the report released June 19, Cell 's impact factor increased to 31.3 fr...

Researchers identify new risk factor gene for rheumatoid arthritis

Scientists at The Feinstein Institute for Medical Research and a team of collaborators from across the country have identified a new risk factor gene for rheumatoid arthritis. The paper will be published in Nature Genetics and the finding brings light to the nature of the disease. The gene, dubb...

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Factor in Biological Technology

Inspiration Biopharmaceuticals Presents Safety Data on IB1001, a Novel Recombinant Factor IX for the Treatment of Hemophilia at the International Society on Thrombosis and Haemostasis (ISTH) Annual Meeting

LAGUNA NIGUEL, Calif., July 14 /PRNewswire/ -- Inspiration Biopharmaceuticals today announced the presentation of positive preclinical safety, toxicology and preliminary pharmacokinetic data on its lead product, IB1001, a novel recombinant Factor IX product to treat patients with he...

AARC Presentation Cites Masimo Patient SafetyNet as Key Factor in 'Improving Patient Outcomes and Reducing Costs' in Post-Acute Care Facilities

Masimo also receives the AARC Zenith Award for Equipment and Service Excellence at the 54th Annual International Respiratory Congress in Anaheim IRVINE, Calif., Dec. 16 /PRNewswire-FirstCall/ -- Masimo (Nasdaq: MASI ), the inventor of Pulse CO-Oximetry and Measure-Through-Motion and Low...

deCODE to Integrate New Genetic Risk Factor for Type 2 Diabetes Into Its deCODEme(TM) Personal Genome Scan Service

REYKJAVIK, Iceland, Dec. 8 /PRNewswire-FirstCall/ -- deCODE genetics (Nasdaq: DCGN ) today announced the discovery by an international consortium of scientists from deCODE and major European and US academic institutions of a single letter variation in the human genome (SNP) that is associated wi...

Portola Data on Its Novel Syk Inhibitors and Novel Universal Factor Xa Inhibitor Antidote to be Presented at 2008 American Society of Hematology (ASH) Meeting

SOUTH SAN FRANCISCO, Calif., Dec. 3 /PRNewswire/ -- Portola Pharmaceuticals, a biopharmaceutical company developing innovative drugs that provide significant advances in cardiovascular disease, inflammatory disease and cancer, today announced that data related to the Company's series of novel comp...

Portola Pharmaceuticals Initiates Phase II Trial of Betrixaban, its Novel Oral Factor Xa Inhibitor for Stroke Prevention in Atrial Fibrillation

SOUTH SAN FRANCISCO, Calif., Nov. 3 /PRNewswire/ -- Portola Pharmaceuticals, a biopharmaceutical company developing innovative drugs that provide significant advances in cardiovascular and inflammatory diseases, and cancer, today announced that it has begun patient enrollment in a large Phase ...

New Study Finds Growth Factor Boosts Productivity in Mammalian Cell Culture

Leading researchers in academia and industry reveal powerful effects of recombinant lactoferrin (tradename: Lacromin) in mammalian cell culture leading to a significant boost in productivity. FORT COLLINS, Colo., Oct. 10 /PRNewswire/ -- A recently published study in the scientific...

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Factor in Biological Products

Goat Anti-Human Factor VIII Polyclonal Antibody, Unconjugated from Abcam

Description: Goat polyclonal to Factor VIII, prediluted ( Abpromise for all tested applications). Antigen: Full length native protein (purified) (Human): Factor VIII from blood. Entrez GeneID: 2157 Swiss Protein ID: P00451...
Company:Abcam

Sheep Anti-Human Factor XI Antibody, Unconjugated from CEDARLANE Laboratories Limited

Description: Anti-Human Factor XI Purified (Polyclonal) (sheep IgG)...
Company:CEDARLANE Laboratories Limited

Mouse Anti-Human Complex IV, assembly factor SURF1 Monoclonal Antibody, Unconjugated, Clone 21H2BG4 from MitoScience LLC

Description: 100 g of monoclonal antibody reactive against the complex IV assembly factor SURF1. Cellular levels of SURF1 are highest in growing cultured cells. SURF1 is an important assembly factor for cytochrome c oxidase which is thought to participate in the folding of subunit II and parallel Cu2+ insertion...
Company:MitoScience LLC

Sheep Anti-Human Factor XIII Antibody, Horseradish Peroxidase Conjugated from CEDARLANE Laboratories Limited

Description: Anti-Human Factor XIII HRPO (Polyclonal) (sheep IgG)...
Company:CEDARLANE Laboratories Limited

Goat Anti-Human FACTOR 8RELATED ANTIGEN Polyclonal Antibody, Unconjugated from AbD Serotec

Description: GOAT ANTI HUMAN FACTOR 8RELATED ANTIGEN...
Company:AbD Serotec

Mouse Anti-Human FACTOR I Monoclonal Antibody, Unconjugated, Clone 3R2/2 from AbD Serotec

Description: MOUSE ANTI HUMAN FACTOR I...
Company:AbD Serotec

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Factor in Biological Definition

Apoptosis

... at each step of these pathways. Tumor necrosis factor ( TNF ), a 157 amino acid inter-cellular signaling...-R1 trigger events that activate the transcription factor nuclear factor kappa B (NF-κB), which induces the expression...

Bacterium

...tively referred to as bacilli , cocci , and spirillum . An additional group, vibrios , are comma-shaped. Shape is no longer considered a defining factor in the classification of bacteria, but many genera are named for their shape (e.g. Bacillus , Streptococcus , Staphylococcus ) and it is an i...

Blood

... correct type is transfused. Other blood products administered intravenously are platelets, blood plasma, cryoprecipitate and specific coagulation factor concentrates. Many forms of medication (from antibiotics to chemotherapy ) are administered intravenously, as they are not readily or adequately ...

Charles Darwin

... the Bank of England ten pound note , replacing Charles Dickens . His impressive and supposedly hard-to-forge beard was reportedly a contributing factor in this choice. Darwin's Portrait on the 10 Note Darwin came fourth in the 100 Greatest Britons poll sponsored by the BBC and voted for by t...

Chromatography

...time R t or t R , the time between injection and detection. In interrupted development systems like TLC the retention is measured as the retention factor R f , the run length of the compound divided by the run length of the eluent front: The retention of a compound often differs considerably ...

Diabetes mellitus

...e is also a strong inheritable genetic connection in type 2 diabetes: having relatives (especially first degree) with type 2 is a considerable risk factor for developing type 2 diabetes. The majority of patients with type 2 diabetes mellitus are obese - chronic obesity leads to increased insulin resist...
Factor in Biological Dictionary

Transcription factor

In the field of molecular biology, a transcription factor is a protein that binds to specific DNA sequences and thereby controls the transfer of genetic information from DNA to mRNA. Transcription factors perform this... Sp1 is a human transcription factor involved in gene expressio...

Splicing factor

ASF serine-rich 1 or SFRS1, is a protein which in humans is encoded by the SFRS1 gene. ASF SF2 and is found on chromosome 17. The resulting splicing factor is a protein of approximately 33 kDa. ASF SF2 also mediates... a b "Entrez Gene: SF3B1 splicing factor 3b, subunit 1, 1...

Sigma Factor

A sigma factorfactor ) is a prokaryotic transcription initiation factor that enables specific binding of RNA polymerase to gene promoters. Different sigma factors are activated in response to different environmental conditions. Every molecule of RNA polymerase... In the regula...

Rhesus factor

The term Rhesus (Rh) blood group system refers to the 5 main Rhesus antigens as well as the many other less frequent Rhesus antigens. The terms Rhesus factor and Rh factor are equivalent and refer to the Rh D antigen only. The Rhesus Factor . GENOTYPING ... become necessary and, a...

Elongation factor

Elongation factors are a set of proteins that facilitate the events of translational elongation , the steps in protein synthesis from the formation of the first peptide bond to the formation of the last one. Interaction of elongation factor -1alpha and pleckstrin homology doma...

Zinc finger

... ... A zinc finger consists of two antiparallel β strands, and an α helix. ... The zinc finger protein TFIIIA, a positive transcription factor of the 5S RNA ... Brief and Straightforward Guide: What Is a Zinc Finger ? ... Zinc finger proteins often bind to DNA and RNA because thei...

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