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exerts in Medical News

Cannabis exerts protective effect against cancer

New research suggests that cannabis smokers are at less risk of developing cancer than cigarette smokers. Although the chemical structures of marijuana and tobacco are strikingly similar, //tobacco has the added nemesis of nicotine in it while cannabis contains tetrahydrocannabinol (THC, the active...

Highmark Provides Pediatricians With Resources to Combat Childhood Obesity

...of dollars to help keep quality health care programs affordable and to support community-based programs that work to improve people's health. Highmark exerts an enormous economic impact throughout Pennsylvania. A recent study states that Highmark's positive impact exceeded $2.5 billion. The company provides...

Highmark Inc. Awards $14,000 to 28 Pennsylvania Nonprofit Organizations

...of dollars to help keep quality health care programs affordable and to support community-based programs that work to improve people's health. Highmark exerts an enormous economic impact throughout Pennsylvania. A recent study states that Highmark's positive impact exceeded $2.5 billion. The company provides...

Human cells secrete cancer-killing protein, UK study finds

...inst cancer cells, leaving healthy cells unharmed. Few other molecules are known to exhibit such selectivity. One molecule, known as TRAIL, also exerts cancer-cell-specific effects. However, Rangnekar's most recent study discovered that apoptosis inducible by TRAIL is dependent upon extracellular Par-...

Feel Fun, Fit & Fabulous! At the 2009 Women's Health Conference

...e and services. Highmark offers the widest range of products, access to all area hospitals and the most responsive customer service. Highmark exerts an enormous economic impact throughout Pennsylvania. A recent study states that Highmark's positive impact exceeded $2.5 billion. Employing more than ...

Transdel Pharmaceuticals Completes Enrollment in Phase 3 Clinical Study for Novel Topical Pain Treatment

...er the active drug, ketoprofen, a non-steroidal anti-inflammatory drug ("NSAID"), through the skin directly into the underlying tissues where the drug exerts its well-known anti-inflammatory and analgesic effects. The Company intends to leverage its Transdel(TM) platform technology to expand and create a p...

Fat-Cell Protein May Reduce Diabetes Risk

...am said that he and his colleagues believe that adiponectin isn't just a marker for a decreased risk of type 2 diabetes, but that the protein actually exerts a causal effect on the development of the disease. He said that in animal studies, when adiponectin is injected, metabolic differences occur. And, acc...

Effective pain treatment for cancer patients?

...fected area is painful," explained Professor Dr. Kuner. But not just touching, even tumor growth itself causes pain, for the expanding tissue also exerts pressure. The cancer cells apparently use the growth factors for their own growth and spread through the nerve pathways and blood vessels to the rest ...

Emory researchers announce Phase III study of progesterone for traumatic brain injury

...is loaded with progesterone receptors. Laboratory studies suggest that progesterone is critical for the normal development of neurons in the brain and exerts protective effects on damaged brain tissue. Donald G. Stein, PhD, Asa G. Candler Professor of Emergency Medicine at Emory School of Medicine and d...

Highmark Program Receives Top Community Leadership Award

...of dollars to help keep quality health care programs affordable and to support community-based programs that work to improve people's health. Highmark exerts an enormous economic impact throughout Pennsylvania. A recent study states that Highmark's positive impact exceeded $2.5 billion. The company provides...
exerts in Medical Technology

Vantia Therapeutics' Lead Candidate VA106483 Demonstrates Positive Anti-diuretic Effect in Phase IIa Trial in Nocturia

...for nocturia and it represents a potential market estimated at more than US$500 million. VA106483 is a novel small molecule drug candidate that exerts its effect directly in the kidney by binding to vasopressin (V2) receptors, which regulate water balance. It was discovered by Vantia from its extensi...

Video: UCB Launches Vimpat(R) in the U.S. for Add-On Treatment of Epilepsy in Adults

...ved in seizure onset Preclinical studies indicate that Vimpat(R) has a novel mechanism of action, although the precise mechanism by which Vimpat(R) exerts its antiepileptic effect in humans is not yet clear. In preclinical studies, the mechanism of action for Vimpat(R) has been shown to involve the ...

Novagali Pharma Presents Results of its Innovative Latanoprost Formulation for Glaucoma

...t that present a safer profile than BAK-containing marketed products for glaucoma. This feature is of paramount importance taken into account that BAK exerts toxicity after long term use and that glaucoma is a chronic disease needing life-long daily treatment. "It is now admitted that BAK has a delet...

New Study First to Confirm Sandostatin LAR(R) Depot Controls Tumor Growth in Patients With Rare Gastrointestinal Tumors

... arm. About Sandostatin LAR Sandostatin LAR is a long-acting, injectable depot dosage form of octreotide acetate, a somatostatin analog which exerts similar pharmacologic effects on the human body as the natural hormone somatostatin. However, octreotide is even more potent than somatostatin at inhi...

RAD001 Combined with Sandostatin LAR(R) Depot and as Monotherapy Controls Growth of Rare Pancreatic Neuroendocrine Tumors

...epot (octreotide acetate for injectable suspension) is a long-acting, injectable depot formulation of octreotide acetate, a somatostatin analogue that exerts similar pharmacologic effects on the human body as the natural hormone somatostatin. However, octreotide is even more potent than somatostatin at inhi...

NanoBio Corporation Completes Interim Analysis of Phase 2 Clinical Trial in Onychomycosis

...0 subjects have been treated with the NB-002 formulation without significant skin irritation, systemic absorption, or other safety concerns. "NB-002 exerts its effect locally by penetrating to reach the nail bed where dermatophytes responsible for onychomycosis reside. It then kills both active hyphae and...

NanoBio Corporation Presents Preclinical and Interim Clinical Data on Topical Treatments for Herpes Labialis and Onychomycosis at AAD 2008

...duct, NB-002, can be safely applied to the skin at doses more than 1,000 times higher than the minimum concentration required to kill fungi. "NB-002 exerts its effect locally by penetrating the skin and diffusing laterally underneath the nail plate to reach the dermatophytes and kill both active hyphae an...

Pharmion and MethylGene Start Phase 2 Combination Clinical Trial With MGCD0103 and Vidaza(R) in Patients With Relapsed or Refractory Hodgkin Lymphoma or Non-Hodgkin Lymphoma

...netic regulators of gene expression. Vidaza reverses the effects of DNA hypermethylation with subsequent tumor suppressor gene re-expression. MGCD0103 exerts its epigenetic effects by acting as an oral isotype-selective HDAC inhibitor. Together, the two act synergistically to induce suppressor gene re-expre...

Highmark Presents Work on MRSA Prevention at National Health Care Quality Conference

...of dollars to help keep quality health care programs affordable and to support community-based programs that work to improve people's health. Highmark exerts an enormous economic impact throughout Pennsylvania. A recent study states that Highmark's positive impact exceeded $2.5 billion. The company provides...

Kosan Presents Updated Data on Hsp90 Inhibitor, Tanespimycin, in Multiple Myeloma at Ash

...b trials (the SUMMIT and CREST trials), 13% Grade 3 neuropathy was observed. This observation supports the hypothesis that treatment with tanespimycin exerts a neuroprotective effect. Tanespimycin in Myeloma Evaluation (TIME) Program The Phase 1b trial is ongoing and multiple patients remain on study. K...
exerts in Medical Products

DHT RIA Test

Description:...ipheral tissues, including genital skin and hair follicles, and are localized intra-cellularly in apparent association with the nuclear membrane. DHT exerts its biological action by intracellular binding to the androgen receptor; and this complex is then transferred to the nucleus where DNA-binding occurs ...
Company:Diagnostic Systems Laboratories, Inc.

Plasma Extractor

Description:... The Plasma Extractor is used to express blood components from collection containers. The spring-loaded front panel exerts pressure on the collection container causing the fluid to transfer until container is clamped off or emptied....
Company:Baxter Healthcare

KyphX Xpander Inflatable Bone Tamp

Description:...cortical bone apart. If the bone being treated is partially healed or has an uninjured area, this will resist balloon expansion. The pressure the bone exerts on the balloon, reflecting its resistance to volume expansion, can be measured on the pressure gauge of the KyphX Xpander Inflation Syringe....
Company:Kyphon, Inc.

Zeuba Vital Knee Support

Features:...it allows skin to breathe and equalizes temperature Compression increases circulation and activates muscles Adjustable Turbo-Pad above the kneecap exerts defined pressure on the thigh to improve coordination when running and jumping High-tech massage ring surrounds the kneecap to activate muscles and ...
Company:Bauerfeind USA, Inc.
exerts in Medical Dictionary

Vasodilation

...d arterial vasodilation . ... Key Words: aldosterone • hypertension • renin • ultrasonics • vasodilation ... BK promotes vasodilation ,1 exerts antiproliferative effects,2 inhibits thrombin ... Although BK is known to cause vasodilation through the B2 receptor and through ... Britannica ...

Osmolality

...ly constant from day to day. ... osmolality ( ′äzmə′lalədē ) ( chemistry ) The molality of an ideal solution of a nondissociating substance that exerts the same osmotic pressure as Serum osmolality is controlled partly by a hormone called antidiuretic hormone (ADH) ... When serum osmolali...

Carotene

...... β- carotene is the most well known representative of the ... Together with α- carotene , β-cryptoxanthin, lutein, zeaxanthin, and lycopene it exerts two major ... ...
exerts in Biological News

Protein that promotes cancer cell growth identified

...nvolved in cancer cell proliferation. In this study they showed that interruption in this association disrupts EGF signaling indicating that Caspase-8 exerts EGF signaling through Src. Cancer results from excessive cell division and reduced cell death. A number of cell death proteins are missing from hum...

Triggering muscle development -- a therapeutic cure for muscle wastage?

...ng periods in zero-gravity conditions during space travel. Dr. Mark Lewis (University College London, UK) will present their latest results on how MGF exerts its effects during his talk at the Society of Experimental Biology Annual Meeting in Glasgow on Wednesday 1st July 2009. When muscles are stretched ...

Oscar Pistorius: Previously confidential study results released on amputee sprinter

...ical to that of intact-limb athletes. Pistorius sprinting mechanics are markedly dissimilar to intact-limb track athletes. At top speed: He exerts considerably less force on the ground in relation to his body weight than intact-limb runners. His foot is in contact with the ground 14% longer on e...

Nonstick and laser-safe gold aids laser trapping of biomolecules

...ission work, such as reproducing and verifying piconewton-scale force measurements using DNA, Perkins says. (A one-kilogram mass on the Earths surface exerts a force of roughly 10 newtons. A piconewton is 0.000 000 000 001 newtons. See JILA Finds Flaw in Model Describing DNA Elasticity NIST Tech Beat, Sept....

Elevated water temperature and acidity boost growth of key sea star species: UBC researchers

...rple to orange to brown and have five rays that can range in length from 10 to 25 centimetres. They are considered a keystone speciesa species that exerts a disproportionate effect on their ecosystem by preying on other animals. ...

Identification of a key molecular pathway required for brain neural circuit formation

... unknown so far," pointed out Dr. Charron. "The molecular pathway my team discovered provides part of an answer." Their recent work showed that Shh exerts its attractive effect through a group of molecules called Src family kinases (SFKs) that, until now, were not known to be linked to Shh function. Rema...

Human role in Indonesian polluting forest fires -- Guido van der Werf in Nature Geoscience

... the influence of two meteorological phenomena. The influence of El Nio on the amount of rainfall was already known, but the Indian Ocean Dipole, that exerts a major influence on the water surface temperature, appeared to be an equally important factor. Although severe drought provides the conditions con...

Vitamin D insufficiency linked to bacterial vaginosis in pregnant women

... complications, such as preterm delivery, there is great interest in understanding how it can be prevented. Vitamin D may play a role in BV because it exerts influence over a number of aspects of the immune system. This hypothesis is circumstantially supported by the fact that BV is far more common in black...

Genetic switch potential key to new class of antibiotics

...rotein chain, thereby decoding the gene. In recent years, groundbreaking work has revealed that RNA is much more than a passive middleman, and instead exerts decisive control over expression. Researchers in the Breaker lab at Yale and Nudler lab at NYU reported in 2002 that regulatory mechanisms arising ...

Fluorescent cancer cells to guide brain surgeons

...he exact borders between tumor and normal brain tissue, which is normally very difficult," explains Eva Frei. "Another problem is that the tumor often exerts pressure on the meninx so that, when it is opened for surgery, the tumor shifts or changes its shape." The new method takes account of this 'brain shi...
exerts in Biological Technology

Lixte Biotechnology Holdings' Lead Compound, LB-1.2, Enhances the Effectiveness of Standard Cancer Chemotherapy in Animal Models

...ings of the National Academy of Science (US). The print version will appear July 14. Dr. John S. Kovach, President and CEO of Lixte, said "LB-1.2 exerts anti-cancer activity directly on the cancer cell and, more dramatically, by preventing cancer cells from recovering from DNA-damage produced by standa...

Europium discovery

... of the diamond anvils. Pressure is applied to the sample space by inflating a doughnut-like bellow with helium gas. Much like a woman in stilettos exerts more pressure on the ground than an elephant does because the woman's force is spread over a smaller area, a small amount of helium gas pressure (60 a...

Novagali Pharma Announces FDA Clearance of IND for Phase III of Catioprost(R), its Cationic Emulsion of Latanoprost in Patients With Glaucoma

...f latanoprost that present a safer profile than BAK-containing marketed products for glaucoma. This is a major advantage since it is admitted that BAK exerts toxicity after long term use and that glaucoma is a chronic disease needing life-long daily treatment. Furthermore, the stability product profile allo...

Transdel Pharmaceuticals, Inc. Retains The Investor Relations Group

...the passage of ketoprofen, a non-steroidal anti-inflammatory drug (NSAID), through the skin barrier to reach targeted underlying tissue where the drug exerts its prolonged localized anti-inflammatory and analgesic effect. The Company is also investigating other novel and generic drugs and promising therapeu...

EntreMed's ENMD-2076 Demonstrates Tumor Regression in Human Colon Cancer Model

...sing positron emission tomography (PET) demonstrated a substantial decrease in tumor metabolic activity in animals treated with ENMD-2076. ENMD-2076 exerts its effects through multiple mechanisms of action, including antiproliferative activity and the inhibition of angiogenesis. ENMD-2076 has demonstrated...

Trap and zap: Harnessing the power of light to pattern surfaces on the nanoscale

... centimeter) in size. The key innovation is the use of a second, highly focused laser, which points directly down onto the bead. This intense light exerts a physical force on the bead, trapping it in the beam and pushing it down toward the surface. The surface pushes back with a constant force, and the b...

Fontus Pharmaceuticals Acquires Nephrology and Endocrinology Drug from Roche Laboratories Inc.

...ion of calcium from the gastrointestinal tract and its utilization in the body. The calcitriol in ROCALTROL is believed to be the active hormone which exerts vitamin D activity in the body. ROCALTROL improves calcium absorption in patients who have severe vitamin D deficiencies commonly associated with CRF,...

Genetic pathway critical to disease, aging found

...on (Feb. 21, 2008) of the journal Nature, a team of University of Wisconsin-Madison scientists reports the discovery of a gene expression pathway that exerts a sweeping influence over the process of oxidative stress. The finding is important because at its foundation it represents a master pressure point...

JADO Reports Clinical Proof of Concept With Raft Modulator in Atopic Dermatitis

...om a Phase IIa clinical trial of its lead RAFT modulator TF002 in patients with severe atopic dermatitis. TF002, a topical formulation of miltefosine, exerts its anti- inflammatory activity via RAFT modulation. RAFTS are sub-compartments in the lipid membrane of cells that play a role in the complex physiol...

Religion colors Americans' views of nanotechnology

...cience, Dietram Scheufele, a University of Wisconsin-Madison professor of life sciences communication, presented new survey results that show religion exerts far more influence on public views of technology in the United States than in Europe. "Our data show a much lower percentage of people who agree th...
exerts in Biological Products

Mouse Anti-PRKAR2 Monoclonal Antibody, Unconjugated, Clone RS17 from GeneTex

Description:... Mouse monoclonal [RS17 ] to PRKAR2 cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins. ...
Company:GeneTex

Anti-IRS 2, phospho (Ser731) Polyclonal Antibody, Unconjugated from BioSource International (Invitrogen)

Description:... Insulin exerts its effects by binding to the insulin receptor, a disulfide-linked heterotetrameric protein comprised of two Alpha subunits and two Beta subunits arra...
Company:BioSource International (Invitrogen)

Recombinant RNasin® Ribonuclease Inhibitor from Promega

Description:...e Inhibitors have broad spectrum RNase inhibitory properties, including the inhibition of eukaryotic RNases of the neutral type (1). The 50kDa protein exerts its inhibitory effect by noncovalently binding to RNases in a 1:1 ratio. The Ki value for the binding of RNasin Ribonuclease Inhibitor to RNase (e.g.,...
Company:Promega
exerts in Biological Definition

DNA

...helix makes one complete turn about its axis. This frequency of twist (known as the helical pitch ) depends largely on stacking forces that each base exerts on its neighbors in the chain. Supercoiled DNA The B form of the DNA helix twists 360 per 10.6 bp in the absence of strain. But many molecula...

Muscle

...scle by weight in the human body. At the time when an infant is delivered, the human uterus weighs about 40 oz (1.1 kg). During childbirth, the uterus exerts 25 to 100 lbf (100 to 400 N) of downward force with each contraction. The external muscles of the eye are conspicuously large and strong in relation...

Transmembrane receptor

...le to ions, which then pass through. In other receptors, the transmembrane domains are presumed to undergo a conformational change upon binding, which exerts an effect intracellularly. In some receptors, such as members of the 7TM superfamily, the transmembrane domain may contain the ligand binding pocket (...
exerts in Biological Dictionary

Trophoblast

..., The enveloping layer is now referred to as the trophoblast . It does not contribute directly to ... Trophoblast is an embryonic tissue which exerts a crucial role during ... The trophoblast , in turn, releases paracrine signals which modulate decidual ... ...

Lysozyme

...king ... Cytokines & Cells Online Pathfinder Encyclopaedia ... For lysozyme -like proteins see: LLP. ... Since partially unfolded Lysozyme exerts broad spectrum ... Lysozyme - Definition of Lysozyme at Dictionary.com a free online dictionary ... lysozyme ly·so·zyme (lī'sə-zīm') n. ... ...

Kinase

...lies in worm, notably. the casein kinase 1 (CK1) group (85 in worm: ... protein kinase ( ¦prō′tēn ′kī′nās ) ( biochemistry ) An enzyme that exerts regulatory effects on growth and malignant transformation by Thymidine kinase Crystal structure of a tetramer of thymidine kinase from U. ure...

Binding site

...t tumor ... ... understanding the contribution of binding site sequence "fuzziness" in the ... that each nucleotide in a binding site exerts an independent effect (Benos et ... Information about Binding site in the free online English ... indicated that the common binding site wa...
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