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evade in Medical News

Leukemia cells evade immune system by mimicking normal cells, Stanford studies show

STANFORD, Calif. Human leukemia stem cells escape detection by co-opting a protective molecular badge used by normal blood stem cells to migrate safely within the body, according to a pair of studies by researchers at Stanford University Medical School. "We call it the 'Don't eat me signal,'" ...

Study unmasks how ovarian tumors evade immune system

Scientists at Johns Hopkins have determined how the characteristic shedding of fatty substances, or lipids, by ovarian tumors allows the cancer to evade the body's immune system, leaving the disease to spread unchecked. Ovarian cancer is considered to be one of the most aggressive malignancies, ki...

Researchers uncover more about how poxviruses evade the immune system

Scientists at Saint Louis University and the University of Alabama at Birmingham have uncovered important new information about a key protein that allows viruses such as smallpox to replicate and wreak havoc on the immune system. The findings further our understanding of how the pox family of v...

Jefferson scientists find protein helps pancreatic cancer cells evade immune system and spread

(PHILADELPHIA) A protein that helps prevent a womans body from rejecting a fetus may also play an important role in enabling pancreatic cancer cells to evade detection by the immune system, allowing them to spread in the body. Researchers at Jeffersons Kimmel Cancer Center in Philadelphia foun...

EPA Plan to Evade Required Cuts in Mercury Pollution Challenged in Court by States, Tribes, Health and Environmental Groups

WASHINGTON, Dec. 6 /PRNewswire-USNewswire/ -- Fourteen states and dozens of Native American tribes, public health and environmental groups, and organizations representing registered nurses and physicians appeared in the U.S. Court of Appeals for the District of Columbia today seeking to overtu...

MicroRNAs may be key to HIV's ability to hide, evade drugs, Jefferson scientists find

(PHILADELPHIA) Tiny pieces of genetic material called microRNA (miRNA), better known for its roles in cancer, could be a key to unlocking the secrets of how HIV, the AIDS virus, evades detection, hiding in the immune system. Researchers at Jefferson Medical College in Philadelphia have shown that ...

To evade chemotherapy, some cancer cells mimic stem cells

ATLANTA - Anti-cancer treatments often effectively shrink the size of tumors, but some might have an opposite effect, actually expanding the small population of cancer stem cells believed to drive the disease, according to findings presented today in Atlanta, Georgia at the American Association fo...

Stripping leukemia-initiating cells of their 'invisibility cloak'

...rmal cells that's acquired by these malignant cells," Weissman said. The leukemia stem cells co-opt this ability and take it to an extreme in order to evade macrophage killing. With their colleagues Ravindra Majeti and Mark Chao at Stanford, the researchers further extended their initial findings in mic...

FRC Says Planned Parenthood, Desperate to Hide Agenda, Attacks Hatch and Hides Intent

... the cloning of human beings, and voted against the right of parents to know if their minor child is being taken across state lines for an abortion to evade local law. "Family Research Council is calling on all Americans who support current law to thank Sen. Hatch for protecting the right of Ame...

4 out of 5 CA Voters Demand Health Insurer "Code of Conduct"

...ients... No matter what happens, strong regulatory oversight will be a must to ensure that insurers skilled in denying coverage don't find new ways to evade just claims." (" Insurance Company Schemes ," New York Times , 6/29/09 ). Healthcare decision-making has shifted to health plans rather th...
evade in Medical Technology

Fat Kills Cancer: Turning Stem Cells from Fat Tissue into Personalized, Cancer-Targeted Therapeutics

...s” that seek out and destroy tumors like tiny homing missiles. This gene therapy approach is a novel way to attack small tumor metastases that evade current detection techniques and treatments, the researchers conclude in the July 1 issue of Cancer Research, a journal of the American Association fo...

Researchers Discover Method for Identifying How Cancer Evades the Immune System

...ans for determining which genes have been altered in a tumor to allow it to evade the body’s natural defenses. In time, the researchers believe such an... “The implication is that once you know the mechanism by which tumors evade the immune system, you can match that tumor to available therapies,” ...
evade in Biological News

Hind wings help butterflies make swift turns to evade predators, study finds

ITHACA, N.Y. New tires allow race cars to take tight turns at high speeds. Hind wings give moths and butterflies similar advantages: They are not necessary for basic flight but help these creatures take tight turns to evade predators. "To escape a predator, you don't have to be fast, you just h...

Researchers engineer pancreatic cell transplants to evade immune response

In a finding that could significantly influence the way type 1 diabetes is treated, researchers at Albert Einstein College of Medicine of Yeshiva University have developed a technique for transplanting insulin-producing pancreatic cells that causes only a minimal immune response in recipients. ...

NIAID funds studies of how SARS and bird flu evade antiviral responses

The National Institute of Allergy and Infectious Diseases (NAID), one of the National Institutes of Health, has awarded a contract to the University of Washington (UW) to use systems biology approaches to comprehensively analyze and model the virus-host interactions and cellular response networks ...

How nonstick bugs evade natural fly paper

There are few things more irritating than a fly buzzing around the house. South Africans have an unconventional solution to the problem. They hang up a bunch of Roridula gorgonias leaves. Attracted to the shiny adhesive droplets on the leaf's hairs, the hapless pest is soon trapped by the natura...

How non-stick bugs evade natural fly paper

There are few things more irritating than a fly buzzing around the house. South Africans have an unconventional solution to the problem. They hang up a bunch of Roridula gorgonias leaves. Attracted to the shiny adhesive droplets on the leaf's hairs, the hapless pest is soon trapped by the natura...

Tumor cells evade death through autophagy

Autophagy is a cellular process that enables cells to turnover their contents, something that they do frequently. Autophagy is initiated in tumor cells by chemotherapy and radiation, but it is not known if this contributes to tumor cell death or helps tumor cells survive the anti-cancer therapy. Ho...

Virus uses tiny RNA to evade the immune system

In the latest version of the hide-and-seek game between pathogens and the hosts they infect, researchers have found that a virus appears to cloak itself with a recently discovered gene silencing device to evade detection and destruction by immune cells. The report by Howard Hughes Medical Instit...

Scientists show that tick-borne flaviviruses use a novel mechanism to evade host defenses

Researchers from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have made the surprising discovery that flaviviruses, which cause such serious diseases as West Nile fever, yellow fever and forms of encephalitis, evade immune system defe...

Scary ancient spiders revealed in 3-D models, thanks to new imaging technique

...i and Eophrynus prestvicii, closely related to modern-day spiders. The study reveals some of the physical traits that helped them to hunt for prey and evade predators. The researchers created their images by using a CT scanning device, which enabled them to take 3,000 x-rays of each fossil. These x-rays...

Cancer's distinctive pattern of gene expression could aid early screening and prevention

..., you need to turn the gene off," he says. "A lot of people think of cancer cells turning genes on, like oncogenes, that allow them to grow faster, evade immune surveillance, that sort of thing," Dr. Robertson says. "There are also many genes that they also want to turn off, like ones that tell a cell t...
evade in Biological Technology

Evidence of macroscopic quantum tunneling detected in nanowires

...mplication of knowledge gleaned from research into quantum tunneling could have applications in the field of quantum computing. "If we learn how to evade the factors that currently suppress quantum superpositions at the macro-scale," Bezryadin said, "we would be better positioned to construct quantum bi...

Nature Medicine study shows Peregrine's bavituximab can cure lethal virus infections

...ranes that "flips" and becomes exposed on the outside of the membranes of enveloped viruses and virally infected cells. Exposed PS enables viruses to evade immune recognition and dampens the body's normal responses to infection. By masking the exposed PS, bavituximab and other anti-PS antibodies may bloc...

Sangamo BioSciences Initiates Phase 1 Trial of CCR5-ZFP Therapeutic to Treat HIV/AIDS

...pared to mice given control cells. These data suggest that, in the presence of HIV, the ZFN-modified cells have a selective advantage allowing them to evade infection and destruction leaving them able fight opportunistic infections and HIV itself. About HIV/AIDS and CCR5 HIV stands for Human...

Nature Medicine study shows Peregrine's bavituximab can cure lethal virus infections

...ranes that "flips" and becomes exposed on the outside of the membranes of enveloped viruses and virally infected cells. Exposed PS enables viruses to evade immune recognition and dampens the body's normal responses to infection. By masking the exposed PS, bavituximab and other anti-PS antibodies may bloc...

Telik's Aurora Kinase-VEGFR Dual Inhibitor Program Meets a Preclinical Development Milestone

...f action," said Steve Schow, Ph.D., Vice President of Research at Telik. "The ability to inhibit two targets may reduce the ability of cancer cells to evade the inhibition of one target alone and results in a better outcome." The initial data demonstrating the activity of Telik's lead compounds was prese...

Peregrine Pharmaceuticals Reports Studies Published in 'Science' Highlight Key Role of Phosphatidylserine (PS) in Viral Infections

...l to the ability of the virus to infect cells, and that when PS is blocked, infection cannot occur. The study also discusses how PS helps the virus to evade immune system recognition and destruction, a key secondary mechanism we believe is operative in both the anti-viral and anti-cancer applications of ou...

New approach may render disease-causing staph harmless

...carotenoid gives the S. aureus bacterium its edge. Aureus is Latin for golden. The carotenoid acts as an antioxidant for the bacterium, allowing it to evade attack by the bodys immune cells. By crippling production of the carotenoid, the compound strips Staph of one of its key defenses. The new research...

Arius announces new findings in Trop-2 and CD59 CANCER antibody programs

...been linked to aggressive cancers in the scientific literature, while our CD59 program has demonstrated the ability to foil a cancer cell's ability to evade the immune system," said Dr. David Young, President and CEO. "These programs, in addition to our CD44 cancer stem cell program, were generated through...

Arius highlighted at AACR-NCI-EORTC 2007 International Cancer Conference

...:30-2:30 p.m. and 5:30-7:30 p.m. ARIUS' poster presentation discusses CD59, a widely expressed target in malignant tumors that allows cancer cells to evade the immune system. ARIUS' CD59 targeting antibody has the potential to help to activate the immune system in addition to targeting cells directly. The...

WARF Granted New Antibiotics Patent

...een one new class of antibiotics approved for use in the last 40 years. This is also a very good target because bacteria must mutate in many places to evade a compound that interferes with this binding, thus reducing the chances that a bacteria will become resistant to an antibiotic found with the novel hi...
evade in Biological Definition

Antigenic shift

...ontrasted with antigenic drift which is the natural mutation over time of known strains of influenza (or other things, in a more general sense) to evade the immune system. Antigenic drift occurs in all types of influenza including influenza A, B and C. Antigenic shift, however, occurs only in influen...
evade in Biological Dictionary

Phase variation

... is an immune evasion technique employed by various types of bacteria, including Salmonella species. It involves the switching of surface antigens, to evade specific adaptive immune system responses. Identification of mutants with increased phase variation frequencies. Mapping and analysis of loc...

Antigenic variation

...by which an infectious organism alters its surface proteins in order to evade a host immune response. This change in antigenic profile may occur as t...by which an infectious organism alters its surface proteins in order to evade a host immune antigenic variation ( ′antə¦jenik ′verē′āshən ) ( i...
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