erase

New RNA polymerase discovered in plants

Biologists at Washington University in St. Louis have discovered an entirely new cellular "machine" in plants that plays a significant role in plant flowering and DNA methylation, a key chemical process essential for an organism's development. A team headed by Craig Pikaard, Ph, D., Washington University professor of biology in Arts & Sciences, has discovered a fourth kind of RNA poly...

Biochemists report discovery of structure of major piece of telomerase; implications for cancer

UCLA biochemists have determined the three-dimensional structure of a major domain of telomerase, the enzyme that helps maintain telomeres ?small pieces of DNA on the ends of chromosomes that act as protective caps -- allowing DNA ends to be copied completely when cells are replicated. This is the first major piece of telomerase for which the structure is known. Telomerase plays a key rol...

A little telomerase isn't enough

With seed money from Johns Hopkins Institute of Cell Engineering, a Johns Hopkins geneticist and her team have discovered a critical link between the health of stem cells and the length of the chromosome ends within them. Chromosome ends, or telomeres, are repetitive stretches of DNA that protect chromosomes in much the same way as plastic tips on shoelaces prevent the fabric from fraying....

How brain pacemakers erase diseased messages

Despite the clinical success of the devices, which have been approved by the Food and Drug Administration and can be found in the heads of about 30,000 Americans, the mechanisms by which deep brain...

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Mouse Anti-Mouse Glutathione S-transferase M1 (GSTM1) Monoclonal Antibody, Unconjugated from Lifespan Biosciences

Description:Anti-GSTM1 Monoclonal Antibody Store vial at -20 C prior to opening. Aliquot contents and freeze at -20 C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. <b...
Company:Lifespan Biosciences

Glutathione-S-Transferase (GST) Colorimetric Assay Kit from Sigma-Aldrich

Description:Biochem/physiol Actions: Glutathione-S-transferases (GSTs) are a group of enzymes important in the detoxification of many xenobiotics in mammals. The enzymes protect cells against toxicants by conjugating the thiol group of the glutathione to electrophilic xenobiotics, and thereby defend cells against the mutagenic, carcinogenic, and toxic effects of the compounds. GST activity is presen...
Company:Sigma-Aldrich

Baker's yeast (S. cerevisiae) Phosphoglucose isomerase from Sigma-Aldrich

Description:Physical form: Essentially sulfate-free, powder containing carbohydrate and citrate buffer salts Chem comp: Protein ~ 50% (modified Warburg-Christian)...
Company:Sigma-Aldrich

Mouse Anti-Human Acetylcholinesterase, brain (AChE) Monoclonal Antibody, Unconjugated, Clone 12B4 from AntibodyShop A/S

Description:Acetylcholinesterase (human brain, AChE)...
Company:AntibodyShop A/S

pMIR-mU6-Luc, Mouse U6 Luciferase Control Vector from Mirus Bio Corporation

Description:The potential applications for the use of small interfering RNA (siRNA) molecules to silence gene expression via the RNA interference (RNAi) pathway have generated tremendous interest in the cellular and molecular biology fields. siRNA for experimental use can be synthesized in vitro, either chemically or enzymatically, and then transfected into the target cells in vitro or in vivo. A convenient...
Company:Mirus Bio Corporation

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Novel PCR Enhancing Factor Improves Performance of Pfu DNA Polymerase

pfuturbo DNA polymerase for robust, high-fidelity PCRamplification Holly Hogrefe Brad Scott Kirk Nielson ValerieHedden Connie Hansen Janice Cline Frances Bai Jeff Amberg RondaAllen Mark Madden Stratagene an improved version of Pf...

Pfu DNA Polymerase as a Hot Start Alternative

Stratagene Cloning Systems, Inc. This article describes the important, novel application of Stratagenes PfuDNA polymerase for minimizing PCR cold start mismatched primer-extensionreactions. These mismatched extension rea...

PCR Performance Comparisons Between pfuturbo and Taq DNA Polymerases

pfuturbo DNA polymerase is the superior choice for robusthigh-fidelity PCR amplification Stratagene In this update, we compare the PCR performances of pfuturbo DNApolymerase * ,</...

pfuturbo DNA Polymerase: A High-Performance, High-Fidelity Enzyme Ideal for PCR Cloning

A High-Performance, High-Fidelity Enzyme Ideal for PCR Cloning Stratagene was cloned into the PC...

Stable HeLa Luciferase Reporter Cell Lines Expressing GAL4 Fusion Transactivators

Lisa Hexdall Li Xu Alan Greener Mary Buchanan John Bauer Chao-Feng Zheng Stratagene HLR-CREB, HLR-Elk1, and HLR-cJun, cell lines for...

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Polymerase chain reaction

or <a href="/ ?q=/ Bi...

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Topoisomerase

s, and then ligating...

Telomerase

Clon...

Taq polymerase

ed and remove it if it is incorrect, a process common in higher <a href="/ ?q=/ Biology-Dictionary/ organ...

T7 RNA Polymerase

T7 plasmid</ ...

RNA polymerase

II (Pol II; also known as <a href="/ ...

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Telomerase Vital In Maintaining Ability of Stem Cell to Multiply

Carol Greider, Ph.D., director and professor of molecular biology and genetics in the Johns Hopkins Institute of Basic Biomedical Sciences and colleagues have found that the length of telomeres is important// in ensuring that stem cells are able to divide indefinitely. Telomeres are the ends of the chromosomes that protect genetic information while the chromosome is undergoing division....

Urine testing for telomerase enzyme for bladder cancer diagnosis

Dr Maria Aurora Sanchini and her colleagues from Italy have found a new urine test which detects bladder cancer// in people with high-risk of cancer occurrence. The test which is proved to be 90% accurate is used to measure the level of the enzyme telomerase in urine of patients. The results of the study have been published in the Journal of the American Medical Association. The study wou...

Anti-cholinesterase drugs for treating Alzheimer's not worth the price

The National Institute for Health and Clinical Excellence (NICE) has found that anti-cholinesterase drugs which are used in the treatment of Alzheimer's disease is not very effective in controlling the disease as the cost of the drug // is very high and they have reported that the drug action is not worth its cost. Alzheimer’s disease affects the brain tissues after one reaches forty ye...

Telomerase Expression Linked To Body Mass

Telomerase is an enzyme that is known to have healing properties. It was earlier considered that the lifespan of an organism and the amount of telomerase expressed were// related but it is now been linked to body mass.Telomerase is also known to increase the rate of cancer. Vera Gorbunova, assistant professor of biology at the University of Rochester, conducted a first-of-its-kind s...

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Sterile Cordless Eraser Tips

Description:Sterile cordless eraser tips, packsize is 10/box....
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Wet-Field Hemostatic Eraser Bipolar Tip (18 gauge Straight w/45 bevel tip)

Description:Wet-Field Hemostatic Eraser bipolar tip, packsize is 10/box....
Company:Medtronic Xomed, Inc.

Wet-Field Hemostatic Eraser Bipolar Tip (20 gauge Straight, Long Shaft)

Description:Wet-Field Hemostatic Eraser bipolar tip, packsize is 10/box....
Company:Medtronic Xomed, Inc.

Wet-Field Hemostatic Eraser Bipolar Tip (20 gauge Curved 135)

Description:Wet-Field Hemostatic Eraser bipolar tip, packsize is 10/box....
Company:Medtronic Xomed, Inc.

Wet-Field Hemostatic Eraser Bipolar Tip (20 gauge Curved 150)

Description:Wet-Field Hemostatic Eraser bipolar tip, packsize is 10/box....
Company:Medtronic Xomed, Inc.

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Anadys Pharmaceuticals Nominates ANA598, a Small-Molecule, Non-Nucleoside Inhibitor of The NS5b Polymerase, as a Candidate for Clinical Development in Chronic Hepatitis C Virus Infection

SAN DIEGO, June 20, 2007 /PRNewswire-FirstCall/ -- AnadysPharmaceuticals, Inc. , a biopharmaceutical company committed tothe discovery, development and commercialization of novel medicinesfor the treatment of hepatitis and cancer, announced today that ithas nominated ANA598 as a candidate for clinical development as anorally-administered direct antiviral for the treatment of chronichepat...

Geron Corp. Licensee TA Sciences Announces Landmark 7/07/07 Teleconference to Answer Questions About TA-65, Their Telomerase Activator With Proven Age Management Benefits

NEW YORK, June 15, 2007 /PRNewswire/ -- Telomerase ActivationSciences, Inc. (T.A. Sciences) recently announced the results ofthe Pivotal 2005 Anti-Aging Trial of TA-65, the first human trialever to show demonstrated, measurable and positive anti-agingbenefits from a Telomerase Activator. Statistically significantresults were found in those taking TA-65 across several keyconditions of agi...

Geron's Telomerase Inhibitor Cancer Drug Demonstrates Good Pharmacokinetics and Tolerability in Phase I/II Trial

MENLO PARK, Calif.--(BUSINESS WIRE)--Jun 12, 2007 - GeronCorporation's (Nasdaq:GERN) telomerase inhibitor cancer drug,GRN163L, has demonstrated good pharmacokinetics and tolerability inits ongoing Phase I/II trial involving patients with chroniclymphocytic leukemia (CLL), according to data presented today byAlan Colowick, M.D., M.P.H., the company's president, oncology, atthe Pan Pacific Ly...

Lev Pharmaceuticals Completes Phase III Prophylaxis Trial of C1-Esterase Inhibitor for Hereditary Angioedema

NEW YORK, May 31, 2007 /PRNewswire-FirstCall/ -- LevPharmaceuticals, Inc. ("Lev" or the "Company") announced today thatit has completed patient treatment in the prophylactic portion ofits Phase III clinical trial of C1-esterase inhibitor (C1-INH) forhereditary angioedema (HAE). The clinical trial, designated CHANGE,examined and evaluated the efficacy and safety of C1-INHreplacement thera...

Genelabs Technologies Announces Presentation of Data on Non-Nucleoside HCV Polymerase Inhibitor at 20th International Conference on Antiviral Research Meeting

REDWOOD CITY, Calif., May 02, 2007 /PRNewswire-FirstCall/ --Genelabs Technologies, Inc. announced today that a presentation wasmade today at the 20th International Conference on AntiviralResearch being held in Palm Springs, California, on anon-nucleoside hepatitis C virus (HCV) polymerase inhibitordiscovered by Genelabs. The oral presentation was given by Christopher D. Roberts,Ph...

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