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Epithelial in Medical News

Calorie restriction inhibits, obesity fuels development of epithelial cancers

SAN DIEGO - A restricted-calorie diet inhibited the development of precancerous growths in a two-step model of skin cancer, reducing the activation of two signaling pathways known to contribute to cancer growth and development, researchers at The University of Texas M. D. Anderson Cancer Center re...

Calorie restriction limits Calorie restriction inhibits, obesity fuels development of epithelial can

SAN DIEGO - A restricted-calorie diet inhibited the development of precancerous growths in a two-step model of skin cancer, reducing the activation of two signaling pathways known to contribute to cancer growth and development, researchers at The University of Texas M. D. Anderson Cancer Center re...

Calorie restriction limits and obesity fuels development of epithelial cancers

SAN DIEGO - A restricted-calorie diet inhibited the development of precancerous growths in a two-step model of skin cancer, reducing the activation of two signaling pathways known to contribute to cancer growth and development, researchers at The University of Texas M. D. Anderson Cancer Center re...

Protein-dependent 'switch' regulates intracellular trafficking in epithelial cells

NEW YORK (Dec. 10, 2007) -- With findings highlighted on a recent cover of Developmental Cell, researchers at Weill Cornell Medical College in New York City have shed important new light on key trafficking mechanisms within epithelial cells. Epithelial cells line the outside of nearly all organs. ...

New developments in biomarkers for epithelial ovarian cancer

AMSTERDAM, November 29th 2007 With the genomic revolution radical improvement has been made in methods of detection of ovarian cancer. This is of the utmost importance, since the chances of successful treatment are strongly enhanced with early detection. In a special issue of Disease Markers, pub...

Master Regulatory Gene of Epithelial Stem Cells Identified

The skins ability to replace the tissue it sloughs off is controlled by a variety of genes. A new study from Harvard Medical School published in the May 4 issue of Cell, however, identifies a "master regulator" of this regeneration process not only for skin, but for many epithelial tissues includi...
Epithelial in Medical Technology

Neurocrine Biosciences Presents Elagolix Data

...data reveal that transient inhibition of plasma testosterone and intra-prostatic androgens results in the reduction of prostate weight, a reduction in epithelial proliferation and suppression of prostate growth. If these preclinical results are replicated in men, daily transient inhibition of androgens with a G...

Micromet's Blinatumomab Achieves Primary Endpoint in Phase 2 Study with Acute Lymphoblastic Leukemia Patients

...in's lymphoma (NHL). A second BiTE antibody, MT110, is in a phase 1 clinical trial for the treatment of patients with solid tumors. MT110 binds to the epithelial cell adhesion molecule, or EpCAM, which is overexpressed in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to...

Micromet Presents Update on Blinatumomab's Response Rate and Duration in a Phase 1 Study in Non-Hodgkin's Lymphoma Patients

...in's lymphoma (NHL). A second BiTE antibody, MT110, is in a phase 1 clinical trial for the treatment of patients with solid tumors. MT110 binds to the epithelial cell adhesion molecule, or EpCAM, which is overexpressed in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to...

Boehringer Ingelheim to Present New Phase II Clinical Data on Two Lead Oncology Compounds at ASCO 2009

...ble dual inhibitor of the epidermal growth factor receptor (EGFR) and human epithelial receptor 2 (HER2) tyrosine kinases.(1) It is the first irreversible EGFR-TK...ainie and Russell Schilder. "Novel Approaches in Advancing the Treatment of epithelial Ovarian Cancer: The Role of Angiogenesis Inhibition" J Clin Oncol. 25, 28...

BioInformatics, LLC New Report - Capitalizing on New Opportunities for Stem Cell Products, Now Available

...jority of respondents differentiate their stem cells into hematopoeitic and epithelial cells, other cell types are expected to be of increasing interest over the ...ls are projected to be differentiated states as common as hematopoeitic and epithelial cells. These findings have implications for product development as the cell...

Adult Circumcision Reduces Risk of HIV Transmission Without Reducing Sexual Pleasure

...emoves the skin surface which is most susceptible to HIV infection, reducing not eliminating the risk of contracting HIV. No differences were found in epithelial or keratin thickness between the remnant foreskin, inner foreskin or shaft skin. The second study, by researchers in Seattle, WA; Chicago, IL; W...
Epithelial in Medical Products

Pemphigus Panel-IgG Epithelial Cell Surface Antibodies and Levels of IgG Desmoglein 1 and Desmoglein 3 Antibodies, Serum

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

IgG Epithelial Cell Surface Antibodies

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Prostate Specific Antigen (PSA) - Rapid Test

Description:... Prostate specific antigen (PSA) is a serine protease that is found only in the prostate within the epithelial cells of the acini and ducts. Normal PSA concentration in whole blood or serum is 0.1-2.6 ng/mL. Reports have suggested that elevated level of whole b...
Company:Bio-Quant, Inc.

Centurion SES Epikeratome

Description:...ical device designed to delaminate or separate the epithelial layer of the cornea above Bowman's layer. The Cent...roach, the SES is designed to reduce trauma to the epithelial layer and avoid flap-related complications. This p...ctive surgery such as dry eye, pain, damage to the epithelial layer, improper microkeratome cuts or improper hea...
Company:Norwood Abbey Eye Care

OneStep PSA InstaTest

Description:... Prostate specific antigen (PSA) is a serine protease that is found only in the prostate within the epithelial cells of the acini and ducts. Normal PSA concentration in whole blood or serum is 0.1-2.6 ng/ml. Reports have suggested that elevated level of w...
Company:Bio-Quant, Inc.

NMP22® BladderChek® Kit (1-test kit)

Description:...atient outcome by identifying those patients who may benefit from more or less aggressive management. NMP22 is a Nuclear Matrix Protein found in human epithelial cells. In the urine of healthy individuals, the protein is present at low levels. The majority of patients with bladder cancer release large quantitie...
Company:Matritech, Inc.

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Epithelial in Medical Definition

Thymocyte

...tive selection can occur at the double positive stage in the cortex. However the repertoire of peptides in the cortex is limited to those expressed by epithelial cells, and double positive cells are poor at undergoing negative selection. Therefore the most important site for negative selection is the medulla, o...
Epithelial in Medical Dictionary

Vitamin A

...us ... Get the latest A & D 10,000/ 400 IU reviews, product information and more ... Vitamin A is essential for the maintenance of healthy epithelial tissue, which ... Vitamin A 25,000 IU - by NOW Foods - available now at WebVitamins.com for only $3.58. Free Shipping on U.S. orders over $99 ...

Tissue

...l and diseased tissue microarray, single core per case, 10 ... Test slides ( tissue arrays with catalog numbers ending with 241 or 242) are ... epithelial tissue covers the whole surface of the body. ... This tissue is specialised to form the covering or lining of all internal and ... NewYork-Pre...

Skin

... The skin is the outer covering of the body. In humans, it is the largest organ of the integumentary system made up of multiple layers of epithelial tissues, and guards the underlying muscles, bones, ligaments and internal... Whatever the issue, find the latest skin care and beauty informatio...

Serum

...ti-pollution system, and... Nonetheless, the use of autologous serum may be contraindicated in particular ... serum -derived cultivated corneal epithelial equivalents for the treatment of ... Rejuvenating serum containing Matrixyl 3000 (palmitoyl oligopeptide blended with tetrapeptide-7) and col...

Seborrheic keratosis

...ts of this common, noncancerous skin growth. seborrheic keratosis n basal cell papilloma, verruca senilis Benign, pigmented, superficial epithelial tumors that clinically appear to be pasted on Georgia Health Information and Transparency ... A seborrheic keratosis usually appears as a brow...

Seborrheic keratoses

... n basal cell papilloma, verruca senilis Benign, pigmented, superficial epithelial tumors that clinically appear to be pasted on Seborrhoeic keratoses (...hat develop from ... Seborrheic keratoses are pigmented superficial epithelial lesions that are ... Seborrheic keratoses vary in size and grow slowly....
Epithelial in Biological News

Master regulatory gene of epithelial stem cells identified

The skin’s ability to replace the tissue it sloughs off is controlled by a variety of genes. A new study from Harvard Medical School published in the May 4 issue of Cell, however, identifies a "master regulator" of this regeneration process not only for skin, but for many epithelial tissues includi...

B cells are required for development of epithelial cancer associated with chronic inflammation

Chronic inflammation is linked to the development of certain types of cancer, but mechanisms mediating inflammation during premalignancy are not well understood. A new research study published in the May issue of Cancer Cell identifies B lymphocytes as important regulators of premalignancy associat...

Skin-like tissue developed from human embryonic stem cells

...l line (H9) was directed to form two distinct specialized cell populations. The first population forms the surface layer (ectodermal, the precursor to epithelial tissue), while the second is found beneath the surface layer (mesenchymal). Following the isolation and characterization of these cell population...

New lab test offers better prediction of HIV microbicide safety

...ells that form tight junctions. After treating the epithelial cells with different microbicides, the researchers...infection of the T cells over time. When the epithelial barrier was treated with placebo, HIV was unable t... and PRO 2000 performed well by not disrupting the epithelial barrier. "Our findings strongly suggest that ...

Caltech researchers explore how cells reconcile mixed messages in decisions about growth

...stantly receiving mixed messages. For instance, an epithelial cell might be exposed to one signal telling it to ...best to grow tissues in a laboratory. In normal epithelial tissues, mature cells that are in contact with one...ay between contact inhibition and EGF in groups of epithelial cells, they found that the cells have a threshold ...

New method separates cancer cells from normal cells

... they took advantage of the cells' different shapes and mobility characteristics. Migrating cancer cells tend to be more round and broad while normal, epithelial cells are long and thin with long protrusions on the ends. The researchers designed a channel with "spikes" coming out at 45-degree angles from the wa...
Epithelial in Biological Technology

Micromet Closes $80.5 Million Public Offering of Common Stock

...in's lymphoma (NHL). A second BiTE antibody, MT110, is in a phase 1 clinical trial for the treatment of patients with solid tumors. MT110 binds to the epithelial cell adhesion molecule, or EpCAM, which is overexpressed in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to...

Micromet Receives European Orphan Drug Designation for Treatment of Acute Lymphoblastic Leukemia with BiTE Antibody Blinatumomab

...in's lymphoma (NHL). A second BiTE antibody, MT110, is in a phase 1 clinical trial for the treatment of patients with solid tumors. MT110 binds to the epithelial cell adhesion molecule, or EpCAM, which is overexpressed in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to...

Micromet Announces Pricing of Public Offering of Common Stock

...in's lymphoma (NHL). A second BiTE antibody, MT110, is in a phase 1 clinical trial for the treatment of patients with solid tumors. MT110 binds to the epithelial cell adhesion molecule, or EpCAM, which is overexpressed in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to...

Micromet Announces Public Offering of Common Stock

...in's lymphoma (NHL). A second BiTE antibody, MT110, is in a phase 1 clinical trial for the treatment of patients with solid tumors. MT110 binds to the epithelial cell adhesion molecule, or EpCAM, which is overexpressed in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to...

Micromet, Inc. to Host Conference Call and Webcast to Report Second Quarter 2009 Financial Results on August 6, 2009

...in's lymphoma (NHL). A second BiTE antibody, MT110, is in a phase 1 clinical trial for the treatment of patients with solid tumors. MT110 binds to the epithelial cell adhesion molecule, or EpCAM, which is overexpressed in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to...

Video of EpiDerm Skin Irritation Test (SIT) Method Now Available

...resentation of this ECVAM-validated method." About MatTek - MatTek Corp. is the world's largest independent producer of in vitro human epithelial tissue equivalents. With over 15 years of publicly available QC data and over 400 technical references supporting our claim of "Unsurpassed Long-Term...
Epithelial in Biological Products

CELLection Epithelial Enrich from Dynal Biotech

Description: The kit contains 5 ml CELLection Dynabeads (4.5 m) coated with the monoclonal antibody against the human epithelial antigen EpCAM and DNase Releasing Buffer. For up to 5 log enrichment of epithelial tumour cells directly from blood, bone marrow or MNC. Tumour cells clumps can be enriched from bone...
Company:Dynal Biotech

Dynabeads Epithelial Enrich from Dynal Biotech

Description: The product contains 5 ml Dynabeads® (4.5 μm) coated with the monoclonal BerEP4 against the human epithelial antigen, EpCAM (epithelial cell adhesion molecule). Also available in 40 samples of 2 x 10e7 MNC in 1 ml volume (contains 1 ml Dynabeads®, Cat.No 161.01)...
Company:Dynal Biotech

Mouse Anti-Cytokeratin 8 + 18 + 19 Monoclonal Antibody, Unconjugated, Clone 2A4 from Abcam

Description:...use monoclonal [2A4] to Cytokeratin 8 + 18 + 19 ( Abpromise for all tested applications). Antigen: Cytokeratins isolated from cultured pig kidney epithelial cells. Entrez GeneID: 3856 Swiss Protein ID: P05783...
Company:Abcam

Anti-Integrin alpha6beta1 (VLA6) Monoclonal Antibody, Unconjugated from CHEMICON

Description:... Rat integrin a6b1, mainly associated with epithelial cells. Does not react with rat fibroblasts....
Company:CHEMICON

Human BMP-5 ELISA development Kit, DuoSet Economy Pack from R&D Systems

Description:...of various tissues and organs. BMPs regulate the growth, differentiation, chemotaxis and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells and neuronal cells. Similar to other TGF-beta family proteins, BMPs are highly conserved across animal species. This DuoSe...
Company:R&D Systems

Rabbit Anti-Human ZO-1 Antibody, Unconjugated from Lab Vision

Description:... Tight junctions are complexes of proteins that create intercellular boundaries between the plasma membrane domains of epithelial and endothelial cells. Antigen: Synthetic peptide corresponding to N-terminal of human ZO-1....
Company:Lab Vision
Epithelial in Biological Definition

Anatomy

...gland Parathyroid gland Adrenal gland Pituitary gland Pineal gland Tissues : Connective tissue Endothelial tissue epithelial tissue Glandular tissue Lymphoid tissue Externally visible parts of the human body: Abdomen Arm Back Buttock Chest ...

Antibody

...m of IgA in the outer secretions has also a polypeptide of the same molecular mass (1,5 kD) that is called the secretory chain and is produced by the epithelial cells . It is also possible to find trimeric and even tetrameric IgA. IgM IgM forms polymers where multiple immunoglobulins are covalently link...

Bioinformatics

...e expression (HT) studies. HT studies are often used to determine the genes implicated in a disorder: one might compare microarray data from cancerous epithelial cells to data from non-cancerous cells to determine the proteins that cancer up-regulates and down-regulates. Expression data is also used to infer ...

Cancer

...it originates and by the location of the cell. Carcinomas originate in epithelial cells , e.g. skin , digestive tract or glands . Leukemia starts in th...ithin germ cells . Adult cancers Adult cancers is usually formed in epithelial tissues and are believed often to be the result of a long biological proces...

Bioinformatics

...e expression (HT) studies. HT studies are often used to determine the genes implicated in a disorder: one might compare microarray data from cancerous epithelial cells to data from non-cancerous cells to determine the proteins that cancer up-regulates and down-regulates. Expression data is also used to infer ...

Cell membrane

...to a particular cell face or surface--for example, the "apical" surface of epithelial cells that line the vertebrate gut --and limits how far they may diffus...a membrane surface of cells may show structure. Returning to the example of epithelial cells in the gut, the apical surfaces of many such cells are dense with inv...
Epithelial in Biological Dictionary

Tissue

...e of cancer that develops from certain tissues , such as bone or muscle. ... This document concentrates on soft tissue sarcomas in adults. ... epithelial tissue covers the whole surface of the body. ... This tissue is specialised to form the covering or lining of all internal and ... Increasing ...

Small intestine

...cancer and colorectal cancer. The small intestine is a long coiled tube located in the abdominal cavity. ... In the small intestine , the epithelial cells cover the villi and contain microvilli. ... 6.3 Small Intestine Bacterial Overgrowth. 6.4 Other Diseases. 7 Current Research and Discov...

Secondary palate

...erm ' secondary palate ' ... Medical Dictionary - ' Secondary Palate ' How to search: 1. ... secondary palate . Type: Term. Definitions: ... epithelial Alterations of Secondary Palate Formation. Marcos Alan Vieira BITTENCOURT ... Development of the secondary palate is a complex and critical ev...

Phosphorylation

...nd used books like Advances in Cyclic Nucleotide and Protein Phosphorylation Research... Phosphorylation of p53 Protein in A549 Human Pulmonary epithelial Cells Exposed to Asbestos Fibers, A549 cells, chrysotile, crocidolite, p53, phosphorylation , ... This is the web site designed by SuperIT Web S...

Oviduct

...tions and the ciliary ... BSO-treated oviduct epithelial cells displayed a continued depletion of GSH ove... Required. We generated cloned murine oviduct epithelial cell lines without viral or ... The oviduct epithelial lines did not secrete IFN- in response to the TLR2...

Nucleoside

...e purpose of this study was to investigate the expression of nucleoside /nucleobase transporters on the Statens Seruminstitut rabbit corneal (SIRC) epithelial cell ... Nucleoside analogs were among the first compounds shown to be effective against ... Nucleoside kinase and nucleotide kinase ac...
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