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encode in Medical News

Scientists find shared genetic link between the dental disease periodontitis and heart attack

...se RNA is complementary to the mRNA, and is often carried by the reverse strand, the 'anti-sense' strand of the DNA double helix. This strand does not encode for a protein, but can bind specifically to the messenger RNA to form a duplex. Through this binding, the antisense strand inhibits the protein expre...

Gene signature may predict patient response to therapy for gastrointestinal stromal tumors

...tion of 38 genes that were expressed higher in tumors that did not respond well to imatinib. Of these, they identified 20 KRAB-zinc finger genes that encode for proteins that typically act as transcriptional repressors of other genes. Ten of these genes, Rink says, are located to a single section of Chrom...

Recent developments at Burnham Institute for Medical Research, May 2009

...ral and Molecular Biology . New leads for treating autoimmune diseases Several inflammatory diseases have been linked to a group of genes that encode immune defense proteins, called NLRs. Post-doctoral fellow Benjamin Faustin, in Dr. John Reed's laboratory, in collaboration with Dr. Arnold Satterthw...

Early Alzheimer's Hinders Brain's Effort to Sort Information

...thy people, said the researchers, from the University of Washington in St. Louis. They noted that Alzheimer's may make it more difficult for people to encode what they learn in a strategic way. The study appears in the May issue of Neuropsychology . More information The U.S. National Institute o...

Memory grows less efficient very early in Alzheimer's disease

...and memory, which in healthy people are fairly efficient processes. The authors speculated that Alzheimer's disease makes it harder for people to encode what they learn in a strategic way. Because encoding is the first step in long-term memory, this affects their ability to remember things according to...

HIV handicaps itself to escape immune system pressure

...team studied people in Zambia and South Africa with one form of the HLA gene that helps the immune system control HIV, called HLA-B*5703. HLA genes encode molecules that display fragments of viral proteins, known as epitopes, on the surface of infected cells. When white blood cells known as cytotoxic T l...
encode in Medical Technology

Scientists Unmask Genetic Markers Associated With Psoriasis

... is the first to identify changes in the IL23A gene in psoriasis patients. Notably, two of the previously identified psoriasis genes (IL12B and IL23R) encode proteins that bind to IL23A protein. Variations in the structure any of these three genes may predispose people to chronic immune responses that ultim...

SARS Vaccine Achieves Neutralizing Responses in First U.S. Human Trial

... About DNA Vaccines DNA vaccines may offer both technical and economic advantages compared with conventional vaccine approaches. DNA vaccines encode certain proteins associated with a target pathogen, rather than using any part of the pathogen itself, and can prime the immune system as well as indu...

Raptor Pharmaceuticals Announces Phase 2a Clinical Trial Initiation in Non-Alcoholic Steatohepatitis (NASH)

... well as orphan drug designation from the FDA for DR Cysteamine for the treatment of nephropathic cystinosis, through its December 2007 acquisition of encode Pharmaceuticals. In March 2008, Raptor acquired an exclusive worldwide license to intellectual property from UCSD for the use of cysteamine and DR Cys...

Treatment Corrects Severe Insulin Imbalance in Animal Studies

... a pediatric endocrinologist at The Children's Hospital of Philadelphia. "This type of congenital hyperinsulinism is caused by mutations in genes that encode important potassium channels in the pancreatic beta cells." The study team, from Children's Hospital and the University of Pennsylvania School of Medi...

Vical Announces Breakthrough for Pandemic Influenza DNA Vaccines With Preliminary Human Data

...as they become available." DNA vaccines may offer both technical and economic advantages compared with conventional vaccine approaches. DNA vaccines encode certain proteins associated with a target pathogen, rather than using any part of the pathogen itself, and can prime the immune system as well as indu...

Targeted Genetics Announces Positive Phase 1/2 tgAAC94 Data Presented at Annual European Congress of Rheumatology

...s with significant unmet medical need. Targeted Genetics' proprietary Adeno-Associated Virus (AAV) technology platform allows it to deliver genes that encode proteins to increase gene function or RNAi to decrease or silence gene function. Targeted Genetics' product development efforts target inflammatory ar...
encode in Medical Products

R2844-Z printer/encoder

Description:... Fulfilling the need for a compact RFID printing solution that can encode smart labels at the point of use, the R2844-Z printer/encoder is one of the most versatile in the industry! Designed for printing and encoding smart m...
Company:Zebra Technologies Corporation
encode in Medical Dictionary

Medial

...s on Sporting Goods, Toys, Collectibles, Car Parts, Food, and the Good Things in Life. Neurons in the medial superior olive (MSO) are thought to encode interaural time ... Medial Superior Olive of the Big Brown Bat: Neuronal Responses to Pure Tones, ... Whereas initial learning activated medial...

Genes

...volved in cell divsion and viability. ... Genes are the units of heredity in ... In reality many genes are much larger, as are ... Genes encode the information necessary to construct the chemicals ... Genes and Disease Topic Room. Lead Editor: Alexandre Vieira, Ph.D. ... Epistatic intera...
encode in Biological News

Rice University psychologist finds women's brains recognize, encode smell of male sexual sweat

A new Rice University study published in the Journal of Neuroscience found that socioemotional meanings, including sexual ones, are conveyed in human sweat. Denise Chen, assistant professor of psychology at Rice, looked at how the brains of female volunteers processed and encoded the smell of...

Attention shoppers: Researchers find neurons that encode the value of different goods

Researchers at Harvard Medical School (HMS) report in the April 23 issue of Nature that they have identified neurons that encode the values that subjects assign to different items. The activity of these neurons might facilitate the process of decision-making that occurs when someone chooses between...

LincRNAs serve as genetic air-traffic controllers

...NAs to target specific regions of the genome." Standard "textbook" genes encode RNAs that are translated into proteins, and mammalian genomes contain about 20,000 such protein-coding genes. Some genes, however, encode functional RNAs that are never translated into proteins. These include a ha...

Building memories with actin

...eveal that LTP's actin reorganization occurs in two stages that are controlled by different pathways, a discovery that helps explain why it is easy to encode new memories but hard to hold onto them. If you can't seem to forget those ABBA lyrics you heard in seventh grade but can't remember Lincoln's Gett...

MS study offers theory for why repair of brain's wiring fails

...into functional oligodendrocytes, and the formation of a new myelin sheath -- they measured the activity of 1,040 genes. All of the genes they studied encode transcription factors, which regulate the activity of other genes. Their experiments showed that 50 transcription factors are working during key steps...

Trio of signals converge to induce liver and pancreas cell development in the embryo

...mmon signals that govern development of these specific cell types. The complexity of this system is somewhat like our 26-letter alphabet being able to encode Shakespeare or a menu at a restaurant." Many investigators are now trying to broadly reprogram cells into desired cell fates for potential therapeu...
encode in Biological Technology

Oprah, Luke Skywalker and Maradona -- new study investigates how our brains respond to them

...known to the patient a day or two before the recording took place. Said Professor Quian Quiroga: "These results demonstrate that single neurons can encode concepts in a very abstract way, even if evoked by different sensory modalities" The study breaks new ground by demonstrating how neurons previousl...

Raptor Pharmaceuticals Doses First Patient in Phase 2b Clinical Trial of DR Cysteamine for Cystinosis

... well as orphan drug designation from the FDA for DR Cysteamine for the treatment of nephropathic cystinosis, through its December 2007 acquisition of encode Pharmaceuticals. In March 2008, Raptor acquired an exclusive worldwide license to intellectual property from the University of California, San Diego ...

MIT, BU engineer cellular circuits that count events

...series over again, but it has no way to "remember" what it has counted. The team's second counter, called the DIC (DNA Invertase Cascade) Counter, can encode digital memory, storing a series of "bits" of information. The process relies on an enzyme known as invertase, which chops out a specific section o...

Spring 'blockbuster' movie now showing

...m mechanical property arising from the magnetic field of a spinning electron, carries a directional value of either "up" or "down" that can be used to encode data in the 0s and 1s of the binary system. Spintronic devices promise to be smaller, faster and far more versatile than today's devices because amon...

ImQuest Presents Data on the Anti-Hepatitis B Virus Activity of Pyrimidinediones at the 13th ISVHLD Meeting in Washington D.C.

...tors of HIV replication, but inactive against a panel of other RNA and DNA viruses, suggesting specificity for antiviral activity against viruses that encode a reverse transcriptase. These studies provide a fundamental structural basis for the development of first in class non-nucleoside inhibitors of HBV ...

SENOMYX ANNOUNCES INITIATION OF DEVELOPMENT ACTIVITIES FOR NEW BITTER BLOCKERS

...h the perception of bitter taste (T2Rs). The Company has been granted patent claims that cover the use of amino acids and nucleic acid sequences that encode many T2R receptor subunits, as well as variants of these bitter receptors, for identifying new bitter taste modulators. About Senomyx, Inc. ( ...
encode in Biological Products

pET GST Fusion System 41 from Novagen

Description:...agen has designed two new multi-frame pET vectors, pET-41a-c(+) and pET-42a-c (+). In addition to featuring the powerful T7lac promoter, these vectors encode the GSTTag (220 aa), proteolytic sites, HisTag (6 aa) and STag (15 aa) sequences. In contrast to other commercially available GST-fusion vectors, ...
Company:Novagen

pET GST Fusion System 41 plus Competent Cells from Novagen

Description:...agen has designed two new multi-frame pET vectors, pET-41a-c(+) and pET-42a-c (+). In addition to featuring the powerful T7lac promoter, these vectors encode the GSTTag (220 aa), proteolytic sites, HisTag (6 aa) and STag (15 aa) sequences. In contrast to other commercially available GST-fusion vectors, ...
Company:Novagen

pET GST Fusion System 42 from Novagen

Description:...agen has designed two new multi-frame pET vectors, pET-41a-c(+) and pET-42a-c (+). In addition to featuring the powerful T7lac promoter, these vectors encode the GSTTag (220 aa), proteolytic sites, HisTag (6 aa) and STag (15 aa) sequences. In contrast to other commercially available GST-fusion vectors, ...
Company:Novagen

pET GST Fusion System 42 plus Competent Cells from Novagen

Description:...agen has designed two new multi-frame pET vectors, pET-41a-c(+) and pET-42a-c (+). In addition to featuring the powerful T7lac promoter, these vectors encode the GSTTag (220 aa), proteolytic sites, HisTag (6 aa) and STag (15 aa) sequences....
Company:Novagen
encode in Biological Definition

Apoptosis

... [17] . Among other important work at Horvitz's laboratory, graduate students Hilary Ellis and Chand Desai had made the first discovery of genes that encode apoptosis-inducing proteins: ced-3 and ced-4 . Ron Ellis also identified a gene with an opposite effect: ced-9 . The product of this gene, CED-...

Biology

...etic information generally is carried in chromosomes , where it is represented in the chemical structure of particular DNA molecules . Genes encode the information necessary for synthesizing proteins, which, in turn play a large role in influencing, although, in many instances, do not completely d...

BLAST

...ated in lineage to a certain protein whose amino-acid sequence I know? Where does the DNA that I've just sequenced come from? What other genes encode proteins that exhibit structures or motifs such as the one I've just determined? BLAST is also often as part of other algorithms that require ap...

Culture

...ntary societies. They argued that through the course of their evolution, human beings evolved a universal human capacity to classify experiences, and encode and communicate them symbolically . Since these symbolic systems were learned and taught, they began to develop independently of biological evolution...

Cytoskeleton

..., and these proteins form a helical network beneath the cell membrane that guides the proteins involved in cell wall biosynthesis . Some plasmids encode a partitioning system that involves an actin-like protein ParM . Filaments of ParM exhibit dynamic instability , and may partition plasmid DNA into th...

DNA

...odons signifying the end of the coding region. In many species of organism, only a small fraction of the total sequence of the genome appears to encode protein. The function of the rest is a matter of speculation. It is known that certain nucleotide sequences specify affinity for DNA binding proteins...
encode in Biological Dictionary

Tumor suppressor

... suppressor gene on chromosome 7 that appears to ... Skin Cancer Study Uncovers New Tumor Suppressor Gene ... Tumor suppressor genes encode proteins that normally serve as a brake on cell growth. ... Scientists have discovered that specialized complex sugar molecules that anchor ce...

Tubulin

...tinct isoform. ... Maternally encoded ß1 tubulin is incorporated into zygotic mitotic spindles. ... The four ß- tubulin genes of Drosophila each encode a distinct isoform. ... The ß3- tubulin gene encodes a divergent isoform expressed in a complex developmental ... ... to Tubulin ... in: Isoty...

Spermatids

...rough spermatid injection should be counseled for potential ... oocytes by injecting spermatozoa, spermatids and spermatocytes. ... ... genes encode proteins located in human late spermatids and in sperm tails. ... proteins in the RNA metabolism of late spermatids , presumably in the s...

Silent Mutation

...lent mutations in protein-coding regions. ... Long-held assumptions about " silent " genetic mutations have been torn down, ... ... will still encode leucine, so no discernable change occurs (a silent mutation ) ... The phrase silent mutation is often used interchangeably with the phrase ... ...

Signal Sequence

... proprietary media formulations dramatically increase the expression ... ACES™ Signal Sequence Kit Application Manual (pdf) ... Certain mRNAs encode what is know as a " signal sequence " or leader peptide. ... The signal sequence is then threaded through a pore called the translocon. ... U...

Sigma Factor

...altering sigma factor ... activation of alternative sigma factor -dependent transcription by ppGpp ... The first description of genes that encode σ70-like sigma factors in multicellular eukaryotes. ... A review of the E. coli stationary phase sigma factor σS. ... ...
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