Studies elucidate genetic links between cancer and schizophrenia

Boca Raton, FL, December 8, 2007 A series of studies presented today at the American College of Neuropsychopharmacology (ACNP) annual meeting elucidates evidence that there is a genetic link between schizophrenia and cancer, providing a surprising possible scientific explanation for lower rates o...

Rise in Cigarette Use may Elucidate Asthma Epidemic in Children

A recent research has found that the asthma epidemic in children may be explained by the rise in cigarette use by adults over the past century . The study, conducted by researchers at the Mailman School of Public Health, is published this month in Annals of Allergy, Asthma & Immunology, the ...

Even healthy lungs labor at acceptable ozone levels

...ility in some healthy individuals, to the effects of short-term ozone exposures." Dr. Schelegle also notes the need for further research to further elucidate the precise mechanisms that determine an individual's ozone responsiveness in both healthy and susceptible populations. "Understanding how these mecha...

Damon Runyon Cancer Research Foundation awards prestigious fellowships to 17 top young scientists

...ellular "self-cannibalism," is involved in a large number of cancers. Learning how autophagy is coordinated with other cellular processes will better elucidate its multiple roles in cancer. Taiowa A. Montgomery, PhD, with his sponsor Gary Ruvkun, PhD, at Massachusetts General Hospital, Boston, Massachusett...

Joan Massagué wins BBVA Foundation Frontiers of Knowledge Award in Biomedicine

...l from the cell membrane to the nucleus rather like decoding the language it uses to communicate with other molecules and in this way have helped to elucidate one of the fundamental processes controlling cell division. Award presentation ceremony The presentation ceremony will take place on June 18...

Sabinsa Corporation Validates Safety of Garcinia Cambogia Extract in Light of Hydroxycut Warning

... human clinical trials further supports the safety aspects of (-)-HCA. Because of its potential health benefits, there has been considerable effort to elucidate the mechanism of action of (-)-HCA. Relevant biological and toxicological studies on G. cambogia extract and (-)-HCA supporting the safety in use of C...

Hispanic children in US at greater risk for obesity than other ethnic/racial groups

...ion argument, and concludes that while acculturation is likely a negative influence, further study is warranted. He writes, "However, we still need to elucidate the mechanisms and the extent to which acculturation to the USA 'mainstream' culture per se explain deterioration in dietary quality, and increased ri...

Music may improve feeding, reduce pain in premature babies: U of A study

... be done in this area, the article says. "Additional methodologically rigorous, randomised controlled trials are warranted to confirm and to further elucidate the benefits of music for neonates before any specific recommendation for the use of music can be made in the neonatal population," state the authors....

Breast cancer etiology may vary by subtype

... cases and were more likely to be Hispanic or Asian. Kwan concludes, "Future research should focus on refinement of tumor subtypes in order to best elucidate how the risk factors may vary. Important modifiable factors that may be related to the development of specific tumor subtypes include obesity in the c...

Five UCSF Scientists Elected to National Academy of Sciences

...ment of genetically engineered mouse models of human cancers, is working to elucidate the mechanisms of cancers and to identify therapeutic strategies. In th... finding, he says, warrants further study in model systems and in humans to elucidate mechanisms that could in turn lead to strategies for harnessing the drugs m...

elucidate in Medical Technology

Alfacell Provides Shareholder Update

...earches from all over the world could be potential buyers of Onconase. We anticipate results shortly. Other studies will be conducted in order to elucidate if Onconase is able to down regulate the protein produced by the MDR1 gene. There is ample evidence this may be the case, and if so, as previously men...

Studies Presented at AACR Annual Meeting Highlight Multiple Immunomodulatory Mechanisms of Peregrine's PS-Targeting Antibodies

...ad anti-PS antibody bavituximab is currently in Phase II clinical trials in advanced breast and lung cancers. "These preclinical studies further elucidate the unique immunomodulatory mechanisms contributing to the observed anti-tumor activity of anti-PS antibodies in preclinical and clinical studies," sa...

MultiCell Technologies Signs Liver Stem Cell R&D Agreement To Develop Products for the Study of Liver Cancer

...l initially focus on the development of a family of life science research reagent tool kits which can be used to isolate liver stem cells, and help to elucidate liver stem cell gene function and their encoded proteins. MultiCell plans to further leverage this research effort involving liver stem cells t...

TorreyPines Therapeutics Muscarinic Agonist NGX267 Meets Primary Endpoint in a Phase II Clinical Trial in Patients with Xerostomia

...btedly justify the design and execution of longer placebo-controlled trials in a larger group of Sjogren's syndrome patients. This will help us better elucidate the full benefit of this novel treatment." "The findings from this study are very promising given the demonstrated efficacy and low incidence...

Complete Genomics and the Institute for Systems Biology Announce Partnership to Conduct the First Human Genome Population Study

...nstrates the value of our sequencing service business model and underscores our vision of using our large-scale, low-cost DNA sequencing technology to elucidate disease pathways," said Dr. Clifford Reid, chairman, president and CEO of Complete Genomics. "We are pleased to be partnering with such a renowned org...

Novel Photoconductive Life Science Research Innovation Enables Rapid, Reproducible, and Non-Invasive Cellular Excitation

...to further our understanding of the mechanisms underlying cellular structure/function relationships. Additionally, it will enable scientists to better elucidate how these mechanisms go awry during disease states and potentially how to better address (and/or prevent) the disease state (and/or injury) following ...

New Data Support Role for Monitoring of Cell-Mediated Immunity in Adult Patients Following Renal Transplantation

...assay in monitoring adult patients after a renal transplant," stated Brad L. Stewart, president of Cylex. "Clearly there is further research needed to elucidate the appropriate standards for use of cell-mediated immunity to monitor risk for infection and rejection in selected patient categories. However, this ...

Michael J. Fox Foundation Funds $1.1 Million for Cutting-Edge Approaches to Parkinson's Disease Under Rapid Response Innovation Awards 2008

...hnology are working to better understand epidemiological findings that have consistently shown smoking may protect against PD. The researchers hope to elucidate the mechanisms by which nicotine may protect dopamine neurons through development and validation of a screening test for small molecules that could in...

Menicon Undertakes With the Novovision Clinic a Paediatric Myopia Control Clinical Trial

...ffers a number of notable features: a prospective design; well matched samples and high resolution ocular biometry measures, which collectively should elucidate whether OK contact lens wear is a feasible method of myopia control. "The MCOS study aims, using a rigorous study design and precise optical measuri...

Lexicon-Genentech Collaboration Yields Potential Therapeutic Targets

...owicz, Ph.D., Lexicon's chief scientific officer. "We believe that our collaboration with Genentech has been enormously fruitful. We have been able to elucidate the function of a number of genes that have shown promise in important areas of medicine." In preclinical studies, treatment with Lexicon's LG842 an...

elucidate in Medical Dictionary

Palpation

..., articles, research, patient ... Palpation of the two patients with C2-3 CBV indicated substantial agreement (K ... Palpation , using touch to elucidate physical findings, plays an important role ... Palpation ,although its role in the cardiac exam is much less then in other ... Palpation is t...

Hypertrophy

... article seeks to examine some of the factors implicated in processes of muscle growth, and, in keeping with the spirit of Mind and Muscle Magazine, elucidate ... Hypertrophy -Specific Training (HST) is based on physiological principles of ... Training >> Workout Programs >> Hypertrophy -Sp...

elucidate in Biological News

'Marathon mice' elucidate little-known muscle type

Researchers report in the January issue of the journal Cell Metabolism, published by Cell Press, the discovery of a genetic "switch" that drives the formation of a poorly understood type of muscle. Moreover, they found, animals whose muscles were full of the so-called IIX fibers were able to run fa...

Mirrors in the mind: New studies elucidate how the brain reflects onto itself the actions of others

In three new independent studies, researchers have deepened our understanding of the remarkable ability of some specialized areas of the brain to activate both in response to one's own actions and in response to sensory cues (such as sight) of the same actions perpetrated by another individual. Thi...

Scientists elucidate the kinome of key model organism

The journal PLoS Genetics has published the findings of a team of scientists at the nonprofit Boston Biomedical Research Institute that provides a whole genome analysis of the protein kinases from a scientifically valuable model organism known as Dictyostelium. Led by Dr. Janet Smith, this stu...

Regenerating worms help elucidate stem cell biology

Using a tiny flatworm best known for its extraordinary ability to regenerate lost tissue, researchers have identified a gene that controls the ability of stem cells to differentiate into specialized cells. The gene encodes a protein that is most similar to the protein PIWI, an important regulator o...

Parasites ready to jump

...ome can become unstable or cancers can develop. We now want to find out whether mammalian cells possess this newly discovered defence mechanism and to elucidate precisely how it works." ( EMBO Journal online, 30 July 2009.) Transposons constitute a significant fraction of the genomes of most higher organis...

Mouse model provides clues to human language development

...ever, proof on a functional level has been lacking until now. The Helmholtz scientists in the German Mouse Clinic conduct comprehensive analyses to elucidate which organs are influenced by a gene in this case the Foxp2 gene. "It is rare for a gene to have only one function," explained Professor Martin Hrab...

A Canada-wide technology platform for mapping the human interactome

...gues on the creation of an international project, the International Interactome Initiative (I3), aimed at developing new technologies and expertise to elucidate the interactome. "Canada has now a powerful tool that will allow its scientists to continue to take the lead in international research on the human...

Lack of happiness hormone serotonin in the brain causes impaired maternal behavior in mice

...ction of the hormone in the body (PNAS, June 23, 2009, Vol. 106, No. 25, pp 10332-10337)*. The researchers "switched off" the gene Tph2 in mice to elucidate the function of the gene in the brain. Tph2 produces the enzyme tryptophan hydroxylase (TPH), which is responsible for the formation of serotonin. ...

Ability to literally imagine oneself in another's shoes may be tied to empathy

..., or figuratively looking over someone's shoulder," Sohee Park, report co-author and professor of psychology, said. "Although future work is needed to elucidate the nature of the relationship between empathy, spatial abilities and their potentially overlapping neural underpinnings, this work provides initial e...

An easy way to find a needle in a haystack by removing the haystack

...ts versatile applications, also in medical diagnostics, the invention is protected by patent. Mass spectrometry is an analytical technique used to elucidate the molecular composition and structure of chemical compounds. In the last two decades mass spectrometry found vast applications in biology, especiall...

elucidate in Biological Technology

First Catalog Cancer Biochip for Sequence Capture Now Available from febit

...short period of time and at low costs." The availability of the automated HybSelect technology supports large-cohort NGS studies that aim to elucidate complex diseases such as cancer, drive forward personalized medicine and investigate new therapeutic delivery models. febit will stay at the forefront...

DNA2.0 Awarded US Patents for Breakthrough Gene Optimization Technology -- Company's Unique Algorithm Enables Expression Yields up to 50 Times Greater than Competing Approaches

...igh protein expression in any host system. We are grateful to the National Science Foundation for funding the three-year study that has allowed us to elucidate the rules on which our patents and algorithms are based." The NSF-supported study involved synthesis of sets of genes and analysis of their e...

Gene Network Sciences Announces Broad Cancer Collaboration With UCSF and Initial Results

...s. Dr. Korn, who is an Associate Professor at UCSF, will lead the UCSF-GNS research partnership. The parties will continue with research to elucidate the RAS-MAPK and PI3K cancer pathways, pathways critical for initiation and progression of many cancers, by building models of breast, pancreatic, and...

Sigma-Aldrich Introduces MISSION(R) esiRNA for Low Cost, High Specificity Pooled RNAi Screening

...rror approach of identifying a single siRNA for gene knockdown and ensures minimal off-target effects. "MISSION esiRNA provides a powerful way to elucidate gene function in cell culture assays," said Dr. Supriya Shivakumar, global marketing manager for Functional Genomics at Sigma-Aldrich. "The pooled for...

Scientists discover 'dancing' algae

... organisms to multicellular ones. This greater understanding of the nature of self-propulsion and collective behaviour of these organisms promises to elucidate key evolutionary steps toward greater biological complexity. Moreover, the flagella of Volvox are nearly identical to the cilia in the human body,...

Preclinical Data From Amgen's Oncology Pipeline to be Presented at AACR

...ntary and opposing effects of angiopoietin-1 and angiopoietin-2 inhibitors on tumor blood vessels and normalization Overview: Aimed to elucidate the effects of Angiopoietin (Ang) 1 and Ang2 on the tumor vasculature of a human colon carcinoma model (Colo205) using peptide-Fc fusi...

Independent Study Corroborates Prana's Strategy to Treat Alzheimer's Disease Patients.

.... Dr Glabe, an author of the paper, noted, "These results are very exciting news for understanding the mechanism of Alzheimer pathogenesis. They help elucidate the fundamental role of metal ions like zinc in causing the formation of Abeta oligomers which damage synapses". Prana's lead Alzheimer's disease...

Heptares Secures GBP21 Million in Series A Fund Raising to Accelerate Development of Pipeline of Small Molecules Against High-Value GPCR Drug Targets

...lecular Biology (Cambridge, UK) based on world-class pioneering research and expertise in GPCRs. In 2008, the StaR technology was used successfully to elucidate the three-dimensional atomic resolution structure of the beta-1 adrenergic receptor, which is the site of action of beta blockers. Heptares' CE...

New Young Investigator Grants for Probiotics Research Announced

...ria out of approximately 4,000 microorganisms that Yakult collects and maintains in-house. The search and detection of new bio-markers is essential to elucidate new functions of probiotics. In order to clarify the effects of these probiotics on health maintenance and pathological amelioration, our institute ha...

DermTech and Rady Children's Hospital-San Diego, Initiate Study to Understand Effects of Vitamin D as a Treatment for Atopic Dermatitis in Children and Young Adults

... using the EGIR technology to evaluate the expression of defense proteins in the affected population before and after treatment with Vitamin D to help elucidate a potentially important part of atopic dermatitis immunology and therapy." Atopic dermatitis is a common, chronic inflammatory skin disease with com...

elucidate in Biological Products

SpliceArray Service from ExonHit Therapeutics Inc.

Description:... SpliceArray is a new generation of microarrays to detect alternative splicing. SpliceArray Service enables you to rapidly elucidate alternatively spliced events in gene families known to be relevant for drug discovery. The service combines ExonHits proprietary splice variant conten...
Company:ExonHit Therapeutics Inc.

elucidate in Biological Definition

Biophysics

... that experimental results are observable with an unaided eye or, at most, optical magnification . Using these techniques, biologists attempt to elucidate the complex systems of interactions that give rise to the processes that make life possible. Biophysics typically addresses biological questions simi...

elucidate in Biological Dictionary

Chloroplast DNA

...ong ... intact DNA molecules from chloroplasts , what would those molecules look like? ... history of research on chloroplast DNA (cpDNA) to elucidate why it has taken more ... Around 500 to 10,000 copies of these chloroplast DNA circles are present per cell. ... Since chloroplast DNA is s...