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elicits in Medical News

Study finds unique HIV vaccine formula elicits strong immune responses

WORCESTER, Mass.Today, Advanced BioScience Laboratories, Inc. (ABL) and the University of Massachusetts Medical School (UMMS) report that their unique HIV vaccine formulation was effective in eliciting strong and balanced immune responses in healthy human volunteers. The findings are published in...

Tips from the journals of the American Society for Microbiology

...ine Immunology . Gastrin-releasing peptide (GRP) is an important human peptide that regulates gastric acid secretion and motor function as well as elicits gastrin release. Previous research has shown that GRP plays a significant role in human cancers through atypical expression of the GRP receptor and G...

FDA's Current Ability to Regulate Genetic Testing is Problematic, FDLI-AAAS Colloquium Attendees Say

... Personalized Medicine Meeting elicits Varying Perspectives WASHINGTON, June 22 /PRNewswire-USNewswire/ -- The Food and Drug Administration's (FDA's) ability to regulate genetic testin...

Amylin Pharmaceuticals to Present Compelling Efficacy and Safety Data From Diabetes Programs at ADA 2009

...the lives of people living with diabetes." KEY AMYLIN ABSTRACTS BEING PRESENTED AT ADA Oral: "Exenatide Once Weekly Treatment elicits Sustained Glycemic Control and Weight Loss Over 2 Years" will be presented by Ken Wilhelm, M.D. on Sunday, June 7 at 8:15 AM CT (9:15 AM ET). ...

Summit VetPharm Offers New Flea Topical Vectra for Dogs & Puppies(TM) For Long-Lasting Protection

...s want fleas killed as quickly as possible to end their dog's suffering," says Dr. Ball. "Oftentimes, the successive feeding activity of fleas on dogs elicits a hypersensitivity skin disorder known as flea allergy dermatitis (FAD). Treatment of dogs with Vectra for Dogs & Puppies(TM) kills fleas and may ...

Ingenious Med Adopts Rapid Software Development, Allowing Customers to Drive Product and Technology

...izes a leadership philosophy, replacing hierarchy with team-work and aligning development projects with customer needs. This collaborative methodology elicits usable, highly developed and maintained software and prompts input from many sources (internally and externally) during the development process. Compr...

Protein can nurture or devastate brain cells, depending on its 'friends,' researchers find

...f the National Academy of Sciences , UT Southwestern research teams studied the protein Cdk5 and discovered both helpful and detrimental mechanisms it elicits in nerve cells. Dr. Amelia Eisch, assistant professor of psychiatry at UT Southwestern, and her colleagues uncovered a beneficial mechanism of the ...

New insights could lead to a better pneumococcal vaccine

...ve way to protect against this potentially devastating disease." Malley's own lab is developing an inexpensive whole-cell pneumococcal vaccine that elicits a robust TH17 response in mice. With support from the Program for Appropriate Technology in Health (PATH), a nonprofit group funded in part by the Bil...

An Alternative to Medicinal Marijuana

...nvironmental Chemistry and Toxicology Laboratory at Berkeley. "We believe our compound does not act directly on the cannabinoid receptors, but instead elicits its effects by blocking the enzymes that degrade the endogenous cannabinoids . . . which in turn stimulate the cannabinoid receptors in the brain." ...

JCI table of contents: March 20, 2008

... best to design preclinical studies that can better predict the risks of novel immunotherapeutics in humans.? TITLE: A CD28 superagonistic antibody elicits 2 functionally distinct waves of T cell activation in rats AUTHOR CONTACT: Holger M. Reichardt University of Goettingen Medical School, Goettinge...
elicits in Medical Technology

Vaxfectin-formulated Measles DNA Vaccine Elicits Long-term Protection and Sterilizing Immunity in Nonhuman Primates

SEATTLE, May 31, 2007 /PRNewswire-FirstCall/ -- Vical Incorporated today announced that a measles DNA vaccine formulated with the company's Vaxfectin(TM) adjuvant elicited protective levels of neutralizing antibodies in juvenile (1 - 2 year old) nonhuman primates confirmed by complete protection f...

GeneThera Announces it is Set to Begin Commercial Testing for Johne's Disease as Soon as January, 2009.

...m and because of the paradoxical immune response of the host animal to infection. During the early sub clinical stages of infection, the microorganism elicits a cell-mediated response by the host that can be characterized by strong delayed-type IV hypersensitivity reactions, lymphocyte proliferative response...

Nventa Presents Findings on Proprietary Toll-like Receptor 3 (TLR3) Agonist, Poly-ICR, at World Vaccine Congress

...-ICR to be a potent vaccine adjuvant targeting the Toll-like Receptor 3 (TLR3) pathway. Data showed that Poly-ICR, in combination with model antigens, elicits strong anti-target antibody and CD8 T-cell immune responses. These findings demonstrate the versatility of Poly-ICR, suggesting that the compound may ...

Pharmaleads' Lead Candidate for Pain, PL37, Enters Phase I

...de Fournie-Zaluski, and is a dual inhibitor of both enzymes responsible for the rapid degradation of enkephalins, the endogenous opiates. It therefore elicits an analgesic effect wherever enkephalins are produced as a response to a painful stimulus, and maintains a high level of these natural analgesic subst...

New Patent Awarded for Antigen-Sparing Vaccines that Elicit Robust Immunity

...N ARBOR, Mich., Jan. 30 /PRNewswire/ -- A needle-free vaccine platform that elicits a robust immune response against a wide array of viruses and bacteria has b...ant protein antigen and apply it to the naso-pharynx, the resulting vaccine elicits strong mucosal and systemic immunity," said James R. Baker Jr., M.D., found...

Takeda Submits New Drug Application for Alogliptin (SYR-322) in the U.S.

...dition, GLP-1 suppresses pancreatic glucagon secretion and subsequent liver glucose production, enhances glucose disposal, slows gastric emptying, and elicits satiety, a feeling of fullness. About Type 2 Diabetes Type 2 diabetes has reached epidemic proportions in the United States with almost 20 million...

Coley Pharmaceutical Group and Pfizer Nominate Additional Anti-Cancer Compound for Clinical Development

...eement, while Coley retains the rights to all other molecules. To date, Coley has designed and characterized nearly 60 unique compounds, each of which elicits a distinct immune stimulatory profile based on its interaction with TLR9. The newly nominated compound, which is the first of two development candidat...

UPDATE: Nile Therapeutics Announces Positive Phase 1a Results of CD-NP, a Selective NPR-B Agonist in Clinical Development for the Treatment of Heart Failure

...b studies of CD-NP infusions in heart failure patients. "In this trial in healthy subjects, we demonstrated that CD-NP can be safely administered and elicits pharmacological and clinical effects which are consistent with the proposed mechanism of action. We are planning additional phase 1 trials in heart fa...

Nile Therapeutics Announces Positive Phase 1a Results of CD-NP, a Selective NPR-B Agonist in Clinical Development for the Treatment of Heart Failure

...b studies of CD-NP infusions in heart failure patients. "In this trial in healthy subjects, we demonstrated that CD-NP can be safely administered and elicits pharmacological and clinical effects which are consistent with the proposed mechanism of action. We are planning additional phase 1 trials in heart fa...

Dynavax's HEPLISAV(TM) Hepatitis B Vaccine Maintains Full Immunogenicity at 50 Weeks in Phase 3 Trial

...clinical studies showing that HEPLISAV has superior immunogenicity and comparable tolerability to Engerix-B. The overall results suggest that HEPLISAV elicits a faster immune response, higher rates of seroprotection and a more durable immune response than conventional vaccine." The Phase 3 trial enrolled mo...
elicits in Medical Dictionary

Vasoconstriction

...wn as pyrexia, a febrile response for unnatural changes ... Prevention of heat loss, such as vasoconstriction . ... Diesel Exhaust Inhalation elicits Acute Vasoconstriction in Vivo, Location: Main Section of EHP Online ... similar magnitude of vasoconstriction was found in ... Definition of ...

Pruritus

...e, and rubbing caused by clothing and sitting. At worst, anal itching causes intolerable... Pruritus (itching) is an unpleasant sensation that elicits the desire to scratch. ... Because of the subjective nature of pruritus , the lack of a precise definition, ... Pruritus often constitutes a ma...

PPD skin test

...kin test . ... ... recommending that anergy skin testing be performed in conjunction with PPD ... PPD -tuberculin skin testing itself elicits a DTH reaction, so persons who have ... You have a better understanding about the basics of tuberculosis. But how do HIV and TB relate? ... You sh...
elicits in Biological News

One signal elicits thousands of answers

Cell signaling mechanisms often transmit information via protein modifications, most importantly the reversible attachment of phosphate, the so-called protein phosphorylation. Researchers at the Max Planck Institute of Biochemistry in Martinsried have now developed a technology to identify and quan...

LSUHSC shows for first time infant inhalation of ultrafine air pollution linked to adult lung disease

... respiratory symptoms including asthma exacerbations," notes Dr. Cormier. "What has come as a surprise is that early exposure to elevated levels of PM elicits long-term effects on lung function and lung development in children." These results could be especially important because the US Environmental Prot...

Glutamine supplements show promise in treating stomach ulcers

...r of Surgery at Harvard Medical School. "Gastric damage develops when the bacteria weakens the stomach's protective mucous coating, damages cells and elicits a robust immune response that is ineffective at ridding the infection." Eventually, she notes, years of infection result in a combination of persisten...

How Toxoplasma gondii gets noticed

...y infectionan event that may also benefit the parasite, which relies on survival of the host to ensure its own transmission. But how the infected host elicits an immune response isn't completely understood. Like many other parasites, T. gondii resides within specialized vesicles inside infected host cells,...

Bright lights, not-so-big pupils

...hich are responsible for our vision in daylight. "The next question was, What makes them so insensitive to light? Perhaps each photon they capture elicits a tiny electrical signal. Then there would have to be bright lightgiving lots of captured photonsfor a signal large enough to influence the brain. Ano...

Scientists study how asbestos fibers trigger cancer in human cells

...School of Environment and Natural Resources. "There seems to be something intrinsic about certain types of asbestos, blue asbestos in particular, that elicits a unique signal, and it triggers inflammation, the formation of pre-malignant cells and, ultimately, cancer." The first protein to be studied is e...

University of Miami biomedical engineer

... oxygen to the brain tissue. "Slowing down the blood flow within the aneurysm leads to natural clotting, which prevents rupture of the aneurysm and elicits a healthy scar-response from the body, thus restoring the diseased arterial segment to its normal state," explained Lieber. Dr. Lieber, is a profes...

A protein sequence associated with Huntington’s disease may become life-saving vaccine component

...nerative Huntington's disease can be safely used as a new generation of vaccine adjuvants. The major component of every vaccine is an antigen that elicits specific immunity to a particular virus, bacteria or even cancer cells. Search for better antigens is one of the most pressing medical and public hea...

Green gel

...reacts to changes in pH. It only fluoresces in the basic range; in a lightly acidic medium, the gel no longer fluoresces. Raising the temperature also elicits a response from the gel. The protein denatures at about 70 C, which quenches the fluorescence and causes the gel to shrink. ...

Trainor Lab characterizes gene essential for prenatal development of nervous system

...omic analyses aimed at identifying the complete set of Cux2-interacting partners. We believe these efforts will be essential to understanding how Cux2 elicits its multiple functions during neurogenesis. Further analysis of Cux2 will make it possible to extend these findings not only to spinal cord develo...
elicits in Biological Technology

Quark Pharmaceuticals Presented At ARVO Data Showing That PF-04523655 Enters Retinal Cells And Elicits Its Pharmacologic Effect Via Target Gene Knock-Down Without Activating TLR3

FREMONT, Calif., May 11 /PRNewswire/ -- Quark Pharmaceuticals, Inc., a development-stage pharmaceutical company discovering and developing novel RNA interference (RNAi)-based therapeutics, today announced that Elena Feinstein, M.D., Ph.D., Chief Scientific Officer, presented a study titled, "PF-04...

Preclinical Proof-of-Concept Studies Published for Novavax Seasonal Influenza Virus-Like-Particle Vaccine

... Trivalent Virus-Like Particle Vaccine elicits Protective Immune Responses against a Variety of Seasonal Influenza Strains in Mice and Ferrets ROCKVILLE, Md., June 24 /PRNewswire-FirstCall/ ...

NanoBio Corporation Raises $12 Million in Series B Financing

...d in patients with cystic fibrosis -- Preclinical data indicating that a single administration of NanoBio's novel intranasal influenza vaccine elicits immune responses in ferrets more than 20 times higher than those generated by two injections of currently approved vaccines "We are pleased w...

Nventa Biopharmaceuticals Announces Third Quarter 2008 Financial Results and Recent Corporate Highlights

...potent vaccine adjuvant targeting the Toll-like Receptor 3 (TLR3) pathway. Data showed that Poly-ICR, in combination with model antigens, elicits strong anti- target antibody and CD8 T-cell immune responses. These findings demonstrate the versatility of Poly-ICR, suggesting that the...

Amylin Pharmaceuticals to Present Promising Data From Diabetes and Obesity Programs at ADA 2008

...hanging therapeutic potential for patients." KEY AMYLIN ABSTRACTS BEING PRESENTED AT ADA Diabetes 1. Oral Late Breaker: "Exenatide Once Weekly elicits Sustained Glycemic Control and Weight Loss Over 52 Weeks" will be presented by John B. Buse, M.D., Ph.D., on Monday, June 9 at 5:50 PM PT (8...

Combination vaccine protects monkeys from ebola and Marburg viruses

...ne that causes the disease in a weakened or dead state (like the polio vaccine) or a genetically similar virus that does not usually cause disease but elicits a protective immune response. The problem with this approach is there is the risk, however small, of viral reactivation and infection. Since the ...

Nasal Vaccine for Smallpox Confers High Levels of Immunity Without Safety Risks

... rouse an adequate immune response against smallpox, the scientists said. The current study in mice demonstrates that NanoBio's killed-virus vaccine elicits a robust immune response because it delivers immune-alerting antigens directly to the lining of the nasal mucosa, where the virus first enters the bod...

Genzyme Study of Myozyme(R) for Late-Onset Pompe Patients Meets Co-Primary Efficacy Endpoints

...real breakthrough for the treatment of Pompe patients, as for the first time it has been demonstrated in a large placebo-controlled trial that Myozyme elicits a positive effect in adults with Pompe disease," said Ans van der Ploeg, M.D., Ph.D., of Erasmus Medical Center in Rotterdam, one of the study's princ...

Bionovo Announces Third Quarter 2007 Financial Results

...ted data on BZL101 at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics showing that BZL101 selectively elicits its cytotoxic activity on cancer cells while avoiding normal cells through the inhibition of glycolysis. -- The results of the MF101 Phase 1/2 cl...

Readers react to 'Cingular confusion'

... Nothing elicits comments as much as a poor customer experience. No column I've written in the last three years has drawn as much comment as the one I wrote in early...
elicits in Biological Definition

Signal transduction

...ulus. In such cases the chain of steps is referred to as a "signalling cascade " or "second messenger pathway" and the result is that a small stimulus elicits a large response. In bacteria and other one-cell organisms , the variety of signal transduction processes of which the cell is capable influence...
elicits in Biological Dictionary

Reflex arc

.... Physiology. Being an ... In a three neuron reflex arc list the direction and the stages of the nerve ... The Reflex Arc . How a Stimulus elicits a Response. A. Knee-Jerk ... called a simple reflex arc . Follow the sensory neuron. from the spindle (receptor) to ... A reflex arc refers ...
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