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ejection in Medical News

Heart Failure Patients With Normal Left Ventricular Ejection Fraction Don't Benefit From Treatment With Angiotensin II Receptor Blocker

Study highlights: -- The angiotensin system inhibitor irbesartan did not improve outcomes in heart failure patients with preserved left ventricular ejection fraction. -- There is not evidence-based therapy for this common condition that predominantly affects women and old...

MULTAQ(R) (dronedarone) for Atrial Fibrillation or Atrial Flutter Now Available in the United States

...ors (i.e., age >70, hypertension, diabetes, prior cerebrovascular accident, left atrial diameter greater than or equal to 50 mm or left ventricular ejection fraction [LVEF] <40%), who are in sinus rhythm or who will be cardioverted. MULTAQ was recently approved by the U.S. Food and Drug Adminis...

Centocor Ortho Biotech Statement on the FDA ODAC Opinion Regarding DOXIL(R) for Treatment of Advanced Breast Cancer

...tudy, 25 patients (8 percent) in the VELCADE for Injection arm and 42 patients (13 percent) in the VELCADE plus DOXIL arm experienced left ventricular ejection fraction decrease (defined as absolute decrease greater than or equal to 15 percent over baseline or a greater than or equal to 5 percent decrease bel...

FDA Approves Multaq(R) for Patients with Atrial Fibrillation or Atrial Flutter

...ude age over 70 years, hypertension, diabetes, prior cerebrovascular accident, left atrial diameter greater than or equal to 50 mm or left ventricular ejection fraction [LVEF] <40%. The FDA approval is based on five international, multi-center, randomized clinical trials involving nearly 6,300 patients. ...

Cell transplantation and cardiac repair

...ciency of cell delivery to the infarcted tissue." The research team also found that higher cell retention correlated with better changes in observed ejection fraction from baseline to a six-month follow-up. "Our data point toward a causal relationship between the total number of cells that participate in ...

Results from 8 late-breaking clinical trials presented at Heart Failure 2009

...(bisoprolol and carvedilol). Ex-DHF is an interesting study which looked at a neglected type of heart failure, diastolic HF (or HF with preserved ejection fraction). There are no proven treatments for this type of heart failure, and this study tested the value of exercise training. The results showed tha...

Anemia associated with greater risk of death in heart disease patients

...creased risk of death. The findings also show that anemia is associated with a poorer degree of left ventricular function and a lower left ventricular ejection fraction, an objective measure of cardiac function. Heart failure is a common and serious chronic illness. A large number of patients with heart fai...

Estrogen May Help Men's Hearts

...chronic heart failure and reduced left-ventricular ejection fraction, high and low concentrations of estradiol...f the men had heart failure and a left ventricular ejection fraction of 28 percent. ejection fraction is a measure of how well the heart is pum...

Schering-Plough Starts Patient Enrollment in Phase 3 Trial for Acadesine, an Investigational Agent Being Studied for Prevention of Complications From Cardiac Surgery

...p CABG. High-risk patients are defined as either female, or males with a previous history of CABG surgery, heart attack, stroke, low left ventricular ejection fraction, or diabetes mellitus. Patients will be randomized to either acadesine or placebo IV infusion started before anesthesia and continued for a ...

Sleep apnea may not be closely linked to heart failure severity

...ant advances in the management of these patients since this phenomenon was recognized. The study involved 218 heart failure patients with reduced ejection fraction (mean 24.7%) who underwent sleep studies between 1997 and 2004. Overall 47% had moderate to severe OSA or CSA. Both conditions were more pre...

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ejection in Medical Technology

MADIT-CRT Trial Meets Primary Endpoint

...oking statements contained in this document. (1) High-risk is defined as QRS width greater than or equal to 130 milliseconds and Left Ventricular ejection Fraction less than or equal to 30 percent. (2) The New York Heart Association clinical classifications of heart failure rank patients as Class I-II-...

New Heart Ultrasound Research Reveals Life-Saving Treatment Alternatives and Advancements for Heart Patients

... comparable improvements in radial strain, strain rate and left ventricular ejection fraction in elderly patients with severe symptomatic aortic stenosis. ... blood in the ventricle immediately after the contraction of the heart) and ejection fraction, (a measurement that determines how well the heart is pumping), wh...

Pixantrone Produces High Rates of Complete and Partial Remissions Even Among Aggressive NHL Patients With Extensive Prior Doxorubicin Treatment or Prior Rituximab Treatment

...m2). No patient developed a severe reduction (>=20%) in left ventricular ejection fraction (LVEF) and only one patient developed congestive heart failure (CH...ubstantial prior doxorubicin exposure reflected by no significant change in ejection fraction from baseline to end of treatment. "This data demonstrates th...

Impulse Dynamics Announces Pivotal Results at the American College of Cardiology Annual Meeting Late-Breaking Session

...r Medicine, Ohio State University Medical Center. In a subgroup representing the "less sick" half of the study population (NYHA Class III with ejection fraction 25% and above), the study found even greater improvements not only in peak VO2 (p=0.001) and quality of life (p=0.003), but also in the prima...

Cardium Reports on Applicability of Corgentin to Stem Cell Therapies: Independent Studies Indicate that Ad5IGF-1 Potentiates Stem Cells to Improve Cardiac Function After Heart Attack

...ed stem cells substantially reduced heart attack related tissue damage (infarct size), caused extensive angiomyogenesis, and improved left ventricular ejection fraction and fractional shortening. MSCs not treated with Ad5IGF-1 had significantly less therapeutic effect in this preclinical model of heart attac...

New England Journal of Medicine Publishes Results From the Landmark ATHENA Trial with Multaq(R) (dronedarone) in Atrial Fibrillation

...l cardiovascular risk factor (hypertension, diabetes, previous ischemic cerebrovascular event, left atrium size greater than 50 mm or left ventricular ejection fraction lower than 40 percent). Patients with recently decompensated heart failure or in New York Heart Association (NYHA) class IV were excluded. Pa...

Study Finds DOXIL(R) Combination Therapy Delays Disease Progression for Patients With Metastatic Breast Cancer

... patients (8%) in the VELCADE for Injection arm and 42 patients (13%) in the VELCADE plus DOXIL arm experienced left ventricular ejection fraction decrease (defined as absolute decrease >/= 15% over baseline or a >/= 5% decrease below institutional lower limit...

Continued Overall Survival Advantage Reported From Pivotal Trial of VELCADE(R) (Bortezomib) for Injection Based Therapy in Patients With Previously Untreated Multiple Myeloma

...on of congestive heart failure, and new onset of decreased left ventricular ejection fraction has been reported, including reports in patients with no risk factors for decreased left ventricular ejection fraction. There have been reports of acute diffuse infiltrative pulmonary d...

Prolonged Progression-Free Survival Demonstrated by VELCADE(R) (Bortezomib) for Injection Based Induction Regimens in Transplant-Eligible Previously Untreated Multiple Myeloma Patients

...on of congestive heart failure, and new onset of decreased left ventricular ejection fraction has been reported, including reports in patients with no risk factors for decreased left ventricular ejection fraction. There have been reports of acute diffuse infiltrative pulmonary d...

Novel VELCADE(R) (Bortezomib) for Injection Based Four-Drug Combination Was Well Tolerated In Previously Untreated Multiple Myeloma Patients

...on of congestive heart failure, and new onset of decreased left ventricular ejection fraction has been reported, including reports in patients with no risk factors for decreased left ventricular ejection fraction. There have been reports of acute diffuse infiltrative pulmonary d...
ejection in Medical Products

Atlas II HF ICD Family

Description:... those patients who remain symptomatic despite stable, optimal medical therapy (as defined in the clinical trials section) and have a left ventricular ejection fraction less than or equal to 35% and a prolonged QRS duration to maintain synchrony of the left and right ventricles in patients who have undergo...
Company:St. Jude Medical, Inc.

Eppendorf Reference Series 2000 Fixed-volume Pipette, 1,000 l

Description:...ate the measuring stroke and blow-out as well as eject the tip. Product features:Eppendorf "pipette/tip" system ensures utmost accuracy and precision. ejection sleeve can be removed to fit into smaller vessels. Smooth-running piston is corrosion-free and chemically resistant . UV-resistant and completely auto...
Company:Eppendorf North America

Eppendorf Reference Series 2000 Fixed-volume Pipette, 200 l

Description:...ate the measuring stroke and blow-out as well as eject the tip. Product features:Eppendorf "pipette/tip" system ensures utmost accuracy and precision. ejection sleeve can be removed to fit into smaller vessels. Smooth-running piston is corrosion-free and chemically resistant . UV-resistant and completely auto...
Company:Eppendorf North America

Eppendorf Reference Series 2000 Fixed-volume Pipette, 100 l

Description:...ate the measuring stroke and blow-out as well as eject the tip. Product features:Eppendorf "pipette/tip" system ensures utmost accuracy and precision. ejection sleeve can be removed to fit into smaller vessels. Smooth-running piston is corrosion-free and chemically resistant . UV-resistant and completely auto...
Company:Eppendorf North America

Eppendorf Reference Series 2000 Fixed-volume Pipette, 20 l

Description:...ate the measuring stroke and blow-out as well as eject the tip. Product features:Eppendorf "pipette/tip" system ensures utmost accuracy and precision. ejection sleeve can be removed to fit into smaller vessels. Smooth-running piston is corrosion-free and chemically resistant . UV-resistant and completely auto...
Company:Eppendorf North America

Eppendorf Reference Series 2000 Fixed-volume Pipette, 2,000 l

Description:...ate the measuring stroke and blow-out as well as eject the tip. Product features:Eppendorf "pipette/tip" system ensures utmost accuracy and precision. ejection sleeve can be removed to fit into smaller vessels. Smooth-running piston is corrosion-free and chemically resistant . UV-resistant and completely auto...
Company:Eppendorf North America

Eppendorf Series 2000 Fixed-volume Pipette, 1 l

Description:...ate the measuring stroke and blow-out as well as eject the tip. Product features:Eppendorf "pipette/tip" system ensures utmost accuracy and precision. ejection sleeve can be removed to fit into smaller vessels. Smooth-running piston is corrosion-free and chemically resistant . UV-resistant and completely auto...
Company:Eppendorf North America

Eppendorf Series 2000 Fixed-volume Pipette, 2 l

Description:...ate the measuring stroke and blow-out as well as eject the tip. Product features:Eppendorf "pipette/tip" system ensures utmost accuracy and precision. ejection sleeve can be removed to fit into smaller vessels. Smooth-running piston is corrosion-free and chemically resistant . UV-resistant and completely auto...
Company:Eppendorf North America

Eppendorf Series 2000 Fixed-volume Pipette, 5 l

Description:...ate the measuring stroke and blow-out as well as eject the tip. Product features:Eppendorf "pipette/tip" system ensures utmost accuracy and precision. ejection sleeve can be removed to fit into smaller vessels. Smooth-running piston is corrosion-free and chemically resistant . UV-resistant and completely auto...
Company:Eppendorf North America

Eppendorf Series 2000 Fixed-volume Pipette, 10 l

Description:...ate the measuring stroke and blow-out as well as eject the tip. Product features:Eppendorf "pipette/tip" system ensures utmost accuracy and precision. ejection sleeve can be removed to fit into smaller vessels. Smooth-running piston is corrosion-free and chemically resistant . UV-resistant and completely auto...
Company:Eppendorf North America
ejection in Medical Dictionary

Vomiting

...t that usually causes vomiting with diarrhea) ... vomiting Forcible ejection of contents of stomach through the mouth. Called also emesis. ... Vomiti... emesis and informally as throwing up ... Vom·it·ing n. The spasmodic ejection of matter from the stomach through the mouth. ... Vomiting may be prece...

Ventricle

... The mean pre-operative left ventricle ejection fraction (LVEF) was 27 ± 8%. The ... Echocardiografically, the mean left ventricle ejection fraction (LVEF) rate was ... ... Ventricle ... of CPPs involve the th...

Systole

...nounced as a long "e" as in "lee. ... Systole - Definition of Systole at Dictionary.com a free online dictionary with ... Systole causes the ejection of blood into the aorta and pulmonary trunk. ... Systole (pronounced sis'to-le, rhymes with &quot;fiscally&quot;) is the ... Syst...

Ejaculation

...culation . Live the life you want for $69. InteliHealth - Featuring Harvard Medical School's consumer health information. ... Ejaculation is the ejection of semen out of the urethra (passageway inside the ... More about Premature Ejaculation : Causes and symptoms Diagnosis Treatment Alternative...
ejection in Biological News

Basis for DNA ejection from single phage particles

Studying phage, a primitive class of virus that infects bacteria by injecting its genomic DNA into host cells, researchers have gained insight into the driving force behind this poorly understood injection process, which has been proposed in the past to occur through the release of pressure accumul...

Life on Earth came from other planets

...ve proven that microbes can easily survive an interplanetary journey. Many species of microbe have evolved the ability to survive a violent impact and ejection into space; the frigid temperatures and vacuum of an interstellar environment; the UV rays, cosmic rays, gamma rays, and ionizing radiation they would...

Slicing chromosomes leads to new insights into cell division

... Hunt's results validate the theory that "polar ejection forces" are at play. Scientists had hypothesized t...ding chromosome movements. In this capacity, polar ejection forces would play a central role separating chromo... had established a direct link until now. Polar ejection forces are thought to arise out of the interaction...

Gene therapy reversed heart damage in heart failure

...ol concurrently. Twelve weeks after receiving the treatment, the rats who received the ARKct had a significantly increased left ventricular ejection fraction. The treatment also reversed the left ventricular deterioration and normalized the neurohormonal status. Dr. Koch said that targeting the GRK...

Scientists discover DNA knot keeps viral genes tightly corked inside shell

... A novel twist of DNA may keep viral genes tightly wound within a capsule, waiting for ejection into a host, a high-resolution analysis of its structure has revealed. Using electron microscopy and three-dimensional computer reconstruction, UC ...

Three Dimensional Visualization of Right Ventricle Provides Important Information for Treatment of Patients with Tetralogy of Fallot, According to a Study in The American Journal of Cardiology

...University of Washington, VentriPoint is developing this breakthrough diagnostic tool that can provide measurement of a heart's volume and ventricular ejection fraction. The VentriPoint Diagnostic System, together with its associated online service, is being developed for a variety of heart related disease st...

Herceptin and chemo improves response rates without major adverse effects in HER2 breast cancer

...re surgery to make it as effective as possible. To minimise the risk, we excluded patients with any previous heart problems and excluded patients with ejection fractions of below 55%. However, our results showed no increase in toxicity for the combination chemotherapy plus trastuzumab compared with chemothera...

Eat less or exercise more? Either way leads to more youthful hearts

..., the left ventricle is a suction pump," Kovcs explains. "Think of the rubber bulb of an old-fashioned bicycle horn you squeeze it (the analog of the ejection phase of the cardiac cycle), then let go (the analog of the filling or diastolic phase) and the rubber bulb springs back to its original shape, suckin...

Building blocks of life formed on Mars

...ar to the Svalbard samples, was during rapid cooling of fluids on Mars. A second event produced organic material from carbonate minerals during impact ejection of ALH 84001 from Mars. The results of this study show that volcanic activity in a freezing climate can produce organic compounds, remarked co-auth...

Geron Demonstrates hESC-derived cardiomyocytes improve heart function after myocardial infarction

...nificantly improved (0.01) in animals that received cardiomyocytes compared to all three control groups. MRI analysis showed improved left-ventricular ejection fraction (p=0.05) in the cardiomyocyte-treated rats compared to controls, as well as a 2.5-fold increase in systolic wall thickening in the infarct zo...

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ejection in Biological Technology

KanekaQH(TM) Ubiquinol Dramatically Boosts Ejection Fraction in Patients With Late-Stage Congestive Heart Failure

Results of first clinical trial indicate pre-converted form of Coenzyme Q10 positively impacted heart function in critically ill subjects HOUSTON, Feb. 18 /PRNewswire/ -- Results from the first clinical trial evaluating ubiquinol's effects on late-stage congestive heart failure showed that th...

PeriCor Therapeutics Reports Positive Preclinical Results of GP531 at the European Heart Failure Congress in Nice

...from 3 mcg/kg/min to 300 mcg/kg/min significantly improves left ventricular (LV) systolic function. GP531 treatment, as compared to placebo, increased ejection fraction and decreased LV end-diastolic pressure, end-diastolic volume and end-systolic volume. This improvement in the heart's pumping ability was ac...

Pixantrone Significantly Increases Complete Remissions, Overall Response Rates, Frequency of Durable Remissions and Progression Free Survival in Patients with Relapsed and Refractory Aggressive Non-Hodgkin's Lymphoma

...bicin equivalent dose at the end of therapy was 513 mg/m2 (with a range of 115 mg/m2 to 1003mg/m2). Data from repeated evaluations of Left Ventricular ejection Fraction ("LVEF") by MUGA (Multi Gated Acquisition Scan) scan demonstrated no consistent dose related decline as has been described for doxorubicin wi...

Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

...iple myeloma study, 25 patients (8%) in the VELCADE for Injection arm and 42 patients (13%) in the VELCADE plus DOXIL arm experienced left ventricular ejection fraction decrease (defined as absolute decrease greater than or equal to 15% over baseline or a greater than or equal to 5% decrease below institution...

Amgen Exercises Option for Exclusive License to Cytokinetics' Cardiac Contractility Program That Includes CK-1827452

...gs also increases the velocity of cardiac contraction and shortens systolic ejection time. In contrast, cardiac myosin activators have been shown to work in th...ocity of cardiac contraction, but instead, in a lengthening of the systolic ejection time, which results in increased cardiac contractility and cardiac function...

Symphony Medical Announces First Patient Successfully Treated With Novel Congestive Heart Failure Therapy

...heart failure. During the surgery to repair the valve, the cardiac surgeon implanted the Algisyl-LVR. Four days following the procedure, the patient's ejection fraction, a measure of the heart's pumping ability, more than doubled, the size of his ventricle was reduced by 22 percent and his ventricle wall thic...

Amorcyte Reports Phase I Results of AMR-001 to Improve Recovery From Severe Heart Attack at ACC Annual Scientific Session

...illion cells showed a trend towards improvement in ejection fraction, the percentage of blood pumped out of a ...apy after AMI, showed a significant improvement in ejection fraction, end systolic volumes, infarct size, redu...on between injected cell volume and improvement in ejection fraction that is suggestive of a dose effect. Thi...

Sopherion Therapeutics, LLC Announces Publication of Phase I/II Myocet(R) (Nonpegylated Liposomal Doxorubicin) Data in Advanced Breast Cancer Patients

... 54 at the recommended phase II dose. Women with measurable, previously untreated, HER-2-overexpressing LABC and MBC - and a baseline left ventricular ejection fraction (LVEF) > 50 percent - received weekly trastuzumab in combination with escalating doses of weekly paclitaxel and nonpegylated liposomal dox...

Nile Therapeutics Announces Positive Results from Phase 1b Safety and Pharmacodynamics Study of CD-NP in Patients with Heart Failure

...ynamic effects of CD-NP on blood pressure and renal function in stable heart failure patients. Patients with NYHA Class II or Class III heart failure, ejection fraction <40% and current signs of fluid overload were included in the study. In this dose escalation trial, four cohorts were administered a sing...

Millennium Announces VELCADE(R) (Bortezomib) for Injection First-Quarter 2008 U.S. Net Sales

...of congestive heart failure, and/or new onset of decreased left ventricular ejection fraction has been reported, including reports in patients with few or no risk factors for decreased left ventricular ejection fraction. There have been rare reports of acute diffuse infiltrative pulmon...
ejection in Biological Products

Eppendorf Reference Series 2000 Fixed-volume Pipette, 2,000 l from Eppendorf North America

Description:...ate the measuring stroke and blow-out as well as eject the tip. Product features:Eppendorf "pipette/tip" system ensures utmost accuracy and precision. ejection sleeve can be removed to fit into smaller vessels. Smooth-running piston is corrosion-free and chemically resistant . UV-resistant and completely auto...
Company:Eppendorf North America

Robotic MBS Thermal Cycler 0.2 ml from Thermo Scientific

Description:... 0.2ml Gradient Block MBSR. Robot compatible block ejection mechanism. Stackable. (96 well block - holds 1 plate 0.2ml x 96 well plate)...
Company:Thermo Scientific

Robotic MBS Thermal Cycler 384 Well from Thermo Scientific

Description:... 384 well block MBSr. Robot compatible block ejection mechanism. Stackable. (384 well block - holds 384 well plate)...
Company:Thermo Scientific
ejection in Biological Definition

Stem cell

...erived stem cells, Dr. Amit Patel at the University of Pittsburgh , Mcgowan Institute of Regenerative Medicine MIRM has shown a dramatic increase in ejection fraction for patients with congestive heart failure. Working with critically ill heart patients, researchers in Vienna have successfully used Mesenc...
ejection in Biological Dictionary

Mature ovum

...one mature ovum (egg cell) ... This is commonly referred to as a "fertilized ovum . ... Overview of contraceptives / birth control methods ... ejection of a mature ovum from an ovary. ... the woman will next release a mature ovum is estimated on ... Definition of matured in the Financial Di...

Arterial system

...d understanding the MAP with its correlations. ... Thus, the arterial system works like a hydraulic filter and lessens the ... ... the systolic ejection in the arterial system followed by a gradual release during diastole. ... driving pressure is that in the arterial system and the end ... I...
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