Effect

Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

Dana-Farber Cancer Institute researchers have identified a molecular mechanism in the liver that explains, for the first time, how consuming foods rich in saturated fats and trans-fatty acids causes elevated blood levels of cholesterol and triglycerides and increases one's risk of heart disease and certain cancers. In the Jan. 28 issue of Cell, scientists led by Bruce Spiegelman, PhD, rep...

Combination therapy boosts effectiveness of telomere-directed cancer cell death

Sometimes apotential target for a drug seems very promising on paper; things areoften very different in reality. Its the case of telomerase inhibitorsto treat cancer; they are supposed to strip the "immortal" (able todivide indefinitely) aspect of cancer cells. Yet, something in the cellseems to block their function, preventing them to inhibit completelythe...

New imaging method gives early indication if brain cancer therapy is effective, U-M study shows

A special type of MRI scan that measures the flow of water molecules through the brain can help doctors determine early in the course of brain cancer regimen if a patient's tumor will shrink, a new study shows. Researchers at the University of Michigan Comprehensive Cancer Center developed the assessment, which they call a functional diffusion map. They used a magnetic resonance imaging sc...

First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers

Two compounds that zero in on cancer cells spreading throughout the body, while ignoring primary tumor cells, could someday give doctors a whole new weapon in the fight against tough-to-treat metastatic disease, according to Weill Medical College of Cornell University researchers. The compounds, called synthetic migrastatin analogues, prevented 91 to 99 percent of metastatic breast cancer...

Alcohol's effects on gene expression in the central nervous system

Alcohol's primary target is the central nervous system (CNS), where it influences neurotransmission to produce intoxication. Scientists can now use microarray technology to study brain function gene by gene. Symposium proceedings published in the February issue of Alcoholism: Clinical & Experimental Research address the effects of alcohol on what is called "gene expression" in the CNS regions...

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Effect at Biology Products

General Side Effect Profile I (GEN SEP I) from Novascreen-a Caliper Life Sciences Company

Description:Compound(s) tested through 63 ligand binding and enzyme assays spanning a broad therapeutic range. This assay panel includes many non human tissue sources and several non-selective assays. Used to determine potential side-effect liabilities of compounds....
Company:Novascreen-a Caliper Life Sciences Company

CNS Side Effect Profile (CNS SEP) from Novascreen-a Caliper Life Sciences Company

Description:Compound(s) tested through a broad panel of 38 ligand binding and enzyme assays targeting the Central Nervous System. Used to determine selecitivty and potential CNS-Side Effect liabilities of compounds....
Company:Novascreen-a Caliper Life Sciences Company

Effect at Biology Technology

Effects of Thermal Cycler Well-To-Well Temperature Uniformity on PCR Results

Michelle Cayouette Jane Moores Jason Capodanno Michael Rahilly Stratagene produces consistent PCR results in every well. The RoboCycler systems uniquedesign uses thermal blo...

Mycoplasma Contamination Reduces the Effect of Lipid-Mediated Transfection of Mammalian Cells

Mycoplasma PCR Primer Set for fast and easy detection of mycoplasmacontamination Yale University Genetic Applications LLC Stratagene Mycoplasma contamination of mammalian cell cultures can substantiallyreduce the potenc...

Effectene Transfection Reagent provides efficient gene delivery to primary neuronal cell cultures

Jochen Meier, Ivonne Strmel, Radu Iosub, Sonja Schmidt, and Rosemarie Grantyn Developmental Physiology, Johannes Mller Institute, Humboldt University Medical School (Charit), Berlin, Germany Efficient delivery of DNA to primary neuronal cell cultures is of critical importance...

Effectene Transfection Reagent

For transfection of a wide variety of cells, particularly effective for primary cells <l...

DirectPrep 96 Miniprep System for cost-effective, high-throughput plasmid DNA purification

QIAGEN introduces the DirectPrep 96 Miniprep System for cost-effective, fully automated, high-throughput DNA purification from high-copy plasmids. Use of a novel lysis chemistry eliminates the need for a lysate clearing step. Plasmid DNA purification is performed using a single plate and a simple bindwashelute...

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Effect at Biology Dictionary

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Effect at Medicine News

New Way to "See" Genes, Evaluate Effectiveness of Gene Therapies Discovered

This technology essentially renders the body transparent and will allow physicians to determine whether gene therapies reach targeted cells and work as they should. "The technology is expected to help patients with cancer and other illnesses, such as cardiovascular disease. The discovery is outlined in the August 2000, issue of the journal Nature Medicine. UCLA researchers plan to tes...

Inhaled Steroids Safe & Effective for Children with Asthma

A 5-year, 8-center study by "Childhood Asthma Management Program" (CAMP) has indicated that inhaled steroids are safe and effective for the long-term treatment of children with mild to moderate asthma. "Although asthma experts around the world have recognized the effectiveness of inhaled corticosteroids in treating asthma, their long term effects in children were not clear, and questions have bee...

Acupuncture May Help Chemotherapy Side Effects

Oriental medical practice of Acupuncture along with commonly used medications may help ease the distressing and disabling side effects of chemotherapy for breast cancer patients, if researchers at National Institute of Health (NIH) are to be believed. According to Dr. Joannieshen MD, MPH, research associate at NIH, electro-acupuncture was more effective in controlling vomiting than...

Morning after pill effective up to five days after having unprotected sex

Canadian researchers say, that the morning after pill, which rescues many women from unwanted pregnancies can be effective up to five days after having unprotected sex. These findings were released after a study conducted by Dr. Isabel Rodrigues, a professor of family medicine at the University of Montreal in Quebec, Canada, and colleagues. The study is published in the March...

Distraction therapy found very effective in postoperative patients

Controlling pain in patients following surgeries has been effectively taken care of by a new therapy called distraction therapy. Doctors at the Johns Hopkins Medical Institutions in the US have distracted patients with images and sounds from nature and have successfully controlled pain in patients following a painful procedure called bronchoscopy, which involves inserting the tube into the nose...

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New Study Shows That Extending Prophylaxis With Clexane / Lovenox (enoxaparin Sodium Injection) to 5 Weeks is More Effective Than 10 Days for Reducing the Risk of Venous Thromboembolism (VTE) in Acutely ill Medical Patients With Reduced Mobility

EXCLAIM is the First International Study to Show That ExtendedThromboprophylaxis Reduces VTE Risk in Acutely-ill Medical PatientsWith a Statistically Significant 44% PARIS, July 8, 2007 /PRNewswire-FirstCall/ --Sanofi-aventisannounced today the results of the EXCLAIM (EXtended CLinicalprophylaxis in Acutely Ill Medical patients) study, which showedthe benefit of extended prophylaxi...

Common Preterm Labor Drug Has More Side Effects Than Alternative, Finds Study from Packard Children's Hospital and Stanford

STANFORD, Calif.--(BUSINESS WIRE)--Jun 29, 2007 - The drug mostcommonly used to arrest preterm labor, magnesium sulfate, is morelikely than another common treatment to cause mild to serious sideeffects in pregnant women, according to a study from researchers atLucile Packard Children's Hospital and Stanford University Schoolof Medicine. Their findings suggest that, since the effectivenessof...

Eurand's Zentase Effective in Treating Exocrine Pancreatic Insufficiency, Studies Show

Zentase Improves Absorption of Fat, Protein and Other Nutrients inPatients with Mild, Moderate or Severe Malabsorption, WhileControlling Symptoms of Exocrine Pancreatic Insufficiency MILAN, Italy and DAYTON, Ohio, June 19, 2007/PRNewswire-FirstCall/ -- Eurand N.V. today announced results thatwere presented at the recent European Cystic Fibrosis Societymeeting in Antalya, Turkey, held June...

Cimzia Effective in Reducing Signs and Symptoms of Rheumatoid Arthritis

New Data Presented at EULAR Confirms Efficacy with Either EveryTwo Weeksn or Monthly Dosing BARCELONA, Spain, 14 June 2007 - 7:00 am CET - New pivotal data(RAPID 1 and RAPID 2) presented at the Annual European Congress ofRheumatology (EULAR) show that Cimzia (certolizumab pegol), thefirst PEGylated, Fc-free anti-TNF, combined with methotrexatetherapy has a rapid and significant eff...

Gabapentin Shown Effective for Fibromyalgia Pain

BETHESDA, Md., June 11, 2007--New research supported by theNational Institutes of Healths National Institute of Arthritis andMusculoskeletal and Skin Diseases (NIAMS) shows that theanticonvulsant medication , which is used for certaintypes of seizures, can be an effective treatment for the pain andother symptoms associ...

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