Chemists create 'Superbowl' molecule; May lead to better health
In a development that could one day score a touchdown for better health, chemists in Australia have created a "superbowl" molecule that shows promise for precision drug delivery, according to a recent study in the Journal of the American Chemical Society. Shaped like a miniature football stadium, the molecule is capable of delivering a wide range of drugs ?from painkillers to chemotherapy cocktai...Protein discovery could unlock the secret to better TB treatment
UCL scientists have found a protein that could unlock the secret to quicker, more effective treatment of TB by waking TB bacteria in the body. Once the TB bacteria are active again, the disease becomes treatable using common drugs like antibiotics. Scientists believe that uncovering the molecular structure of this protein will lead the way to designing drugs which enable treatment of dormant and...Topical treatment shown to inhibit HIV and herpes simplex virus infection
Mount Sinai School of Medicine researchers demonstrated that a gel applied in the vagina provides protection from both the human immunodeficiency virus (HIV) and the herpes simplex Virus. The study, presented at the 12th Conference on Retroviruses and Opportunistic Infections, is the first to show that a gel can retain anti-viral activity within the human vagina. The study, which was fund...Antarctic ice shelf retreats happened before
The retreat of Antarctic ice shelves is not new according to research published this week (24 Feb) in the journal Geology by scientists from Universities of Durham, Edinburgh and British Antarctic Survey (BAS). A study of George VI Ice Shelf on the Antarctic Peninsula is the first to show that this currently 'healthy' ice shelf experienced an extensive retreat about 9500 years ago, more t...Combination therapy boosts effectiveness of telomere-directed cancer cell death
Sometimes apotential target for a drug seems very promising on paper; things areoften very different in reality. Its the case of telomerase inhibitorsto treat cancer; they are supposed to strip the "immortal" (able todivide indefinitely) aspect of cancer cells. Yet, something in the cellseems to block their function, preventing them to inhibit completelythe...Canine Pancreatic Microsomal Membranes from Promega
Description:Microsomal vesicles are used to study co-translational and initial post-translational processing of proteins. Processing events such as signal peptide cleavage, membrane insertion, translocation and core glycosylation can be examined by the translation of the appropriate mRNA in vitro in the presence of these microsomal membranes. In addition, processing and glycosylation events may be studied by...Anti-Heat Shock Protein 75 (hsp75) (TRAP-1) Ab-2 Monoclonal Antibody, Unconjugated from Lab Vision
Description:A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (HSPs), more appropriately called as stress response proteins (SRPs). The Hsp90 family of proteins in mammalian cells consists of Hsp90 alpha and beta, Grp94, and Trap-1 (Hsp75). It was found that human TRAP-1 is localized to mitochondria and exhi...Corning Petri Dish, 60 X 15 mm, Tc -Treated, Sterile from Sigma-Aldrich
Description:This CLS number is a new product number, created to easily match Cornings product number. If showing no availability yet, please order under the old Sigma-Aldrich number (C6421) or contact customer service for assistance. Mfr Desig: Corning 430166...Heated Processing Chamber from Terra Universal, Inc.
Description:Ideal for biocompatibility testing at various temperatures, this chamber provides continuous circulation of air through a clean heating unit to maintain a constant internal temperature up to 140F. Transparent panels allow full visibility, and parting strip shields allow easy access to the work area. Includes a utility shelf....Feature Extraction Software; 2-year License for Not-For-Profit/Academic from Agilent Technologies
Description:Feature Extraction Software reads and processes raw microarray image files to prepare microarray data for analysis. Package contains: * one 2-year license for Feature Extraction valid for NFP/Academic accounts * one CD-ROM containing Feature Extraction software and electronic manual...New Temperature Cycler Features Interchangeable Blocks
Michelle Cayouette Jane Moores Jason Capodanno Michael Steege Michael Rahilly Stratagene Infinitytemperature cycler, a new temperature cycler withinterchangeable blocks for...The Best Enzyme for the Toughest PCR Challenges Improved with New Hot-Start Feature
DNA pol...Greater Amplification Specificity with New Hot Start PCR Enzyme
Taq DNA polymerase makes hot start simple and efficient Jonathan Eads Frances Bai Ronda Allen Holly Hogrefe <p align="...Yeast Protein Production System Features High Yields and One-Step Purification
The ESP system provides high-yield protein production in a eukaryoticorganism Quinn Lu * Bruce Jerpseth * Tim Sanchez * John C. Bauer * AlanGreener Stratagene Cloning Systems, Inc. provides novel opportunities for rapid, inexpensive and high-yield p...Unique Enhanced DNA Polymerase Delivers High Fidelity and Great PCR Performance
Improve reliability of PCR reactions with Herculase enhanced DNApolymerase Stratagene enhanced DNApolymerase,* a novel enzyme formulation that providessuperior performance in both routine and demanding PCR applications. Previous...Advances in Treatment of Cataracts
Cataracts occur when the eye's lens becomes cloudy and obstructs the passage of light to the retina. These obstructions can lead to vision loss. //Cataract is a major cause of blindness in India. Modern corrective surgery requires implantation of artificial lenses, however these implants often leave patients dependent on eyeglasses. But now, a recent study at Harvard Medical School has sh...Recommendations for Treatment of Blood Pressue
The National Heart, Lung, and Blood Institute (NHLBI) and the National High Blood Pressure Education Program (NHBPEP),USA, have come out with recommendations to treat Hypertension.Control of systolic blood pressure is as important as control of Diastolic blood pressure. This is a crucial message for health care providers, patients, and their families. For many years, the importance of low...Thyroid hormone treatment hastens recovery after cardiac surgery
Thyroid hormone treatment after surgery requiring heart bypass speeds recovery in children undergoing correction of congenital heart defects, according to a clinical trial published in The Lancet. The effects were greatest in the patients who underwent long and difficult surgeries. Following trauma or surgery or during a critical illness, thyroid hormone concentrations plummet. Ma...Pancreatitis: Minimially Invasive Procedure Offers Long-Term Pain Relief
Many more patients with chronic pancreatitis can safely turn to a minimally invasive operation for long-term pain relief, according to a new study by Johns Hopkins University physicians. Endoscopic therapy is an effective alternative to more invasive surgery or drugs, says Anthony N. Kalloo, MD, director of GI endoscopy at Hopkins and lead author of the study that appeared in the July...Feeding channel created by malaria parasite - a new target for malaria treatments
Researchers have found pore-like holes in the membranes of red blood cells infected by the deadliest form of the malaria parasite. The parasite, Plasmodium falciparum, apparently uses these holes to supply itself with the nutrients it needs to grow and reproduce. The discovery may lead to the development of new treatments for malaria, a widespread and devastating disease. Mala...Point of Care Strep Tests Speed Treatment, Lower Costs
Beta-hemolytic group A streptococcus (S. pyogenes) is the most common bacterial agent associated with upper respiratory tract infections. Although it usually involves mild symptoms (such as headache, fever or abdominal pain) if left untreated streptococcal infection can worsen and become life-threatening. Early diagnosis and treatment of group A streptococcal pharyngitis has been shown to red...Low-Density Cholesterol Subfractions: Not all LDL-C Particles are Created Equal
Medical conventions are challenged every day. Already in the new year, the effectiveness of cold medicine and the gold standard in breast cancer treatment have been challenged. Standards in cholesterol testing are the latest casualty of medical innovation. For years, cholesterol has been measured by a simple panel o...Rapid HIV Testing Increases Possibility of Treatment
According to a November, 2005 joint press release from UNAIDS (Joint United Nations Programme on HIV/AIDS) and the World Health Organization, the number of people living with HIV globally reached an estimated high of 40.3 million people in 2005, with over 3 million deaths caused by AIDS. The latest data from...Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer
NEW YORK, July 12, 2007 /PRNewswire-FirstCall/ -- ImCloneSystems Incorporated and Bristol-Myers Squibb Company todayannounced results from an open-label Phase III study of ERBITUX(R)(Cetuximab) plus a taxane and carboplatin in the first-linetreatment for metastatic non-small cell lung cancer (NSCLC). Thestudy did not meet its primary endpoint of progression-freesurvival (PFS) as assessed...Positive Aggrastat Results Featured in the Journal of the American College of Cardiology
WINNIPEG, Manitoba - (July 11, 2007) Medicure Inc. (TSX:MPH;Amex:MCU), a cardiovascular focused, biopharmaceutical company,today announced that the two-year, follow-up results from theSTRATEGY (Single High-Dose Bolus Tirofiban and Sirolimus-ElutingStent Versus Abciximab and Bare Metal Stent In Acute MyocardialInfarct...