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Nonlinear Dynamics announces more details of its global partnership with PerkinElmer

Nonlinear Dynamics Ltd, a leading provider of bioinformatics solutions, today announced further details of its global OEM partnership with PerkinElmer, Inc. (NYSE: PKI), a leading provider of drug discovery, life science research and analytical solutions. As detailed in a press release issued last week, PerkinElmer will distribute Nonlinear's full range of 1D, 2D and array software. Howeve...

Technique offers new view of dynamic biological landscape

A new technique for analyzing the network of genetic interactions promises to change how researchers study the dynamic biological landscape of the cell. The technology, which is called epistatic mini array profiles (E-MAP), has already been used to assign new functions to known genes, to uncover the roles of previously uncharacterized proteins, and to define how biochemical pathways and proteins...

High resolution 'snapshots' detail dynamics of a cocaine antibody

Cocaine-binding antibodies have shown some promise in their ability to neutralize cocaine toxicity, but their binding ability is severely impaired by high concentrations of the drug. A catalytic monoclonal antibody such as 7A1, on the other hand, has the ability to regenerate after each new dose of the drug, making it far more effective than others in metabolizing cocaine. The study, which...

Recombination protein dynamics observed with single monomer resolution

Using a sensitive, single-molecule measurement technique, researchers at the University of Illinois at Urbana-Champaign have observed the life cycle of RecA, a protein that plays a major role in repairing damaged DNA. RecA is a DN...

UCLA study of community health project shows how group dynamics affect fitness, eating habits

Imagine break-room vending machines featuring fruit juice and vegetables instead of cookies and soda pop. Consider colleagues who insist on mid-morning group exercise breaks and applaud a lunchtime workout rather than criticizing the cut of the sweat suit. Ponder an organizational culture that encourages walking the stairs instead of riding the elevator. A UCLA-evaluated study of a demons...

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High Sensitivity, Wide Dynamic Range, Horseradish Peroxidase (HRP) ELISA Using the LMax Microplate Luminometer (MaxLine Application Note #41)

Evelyn McGown, Ph.D. and Michael Su, M.S. Molecular Devices Corporation, 8/00 Immunoassays have traditionally employed colorimetric indicators. As such, multiple dilutions of samples were necessary to ensure that they fell within the dynamic range of the assay. Recently, chemiluminescent immunoassays, with gre...

Dynamics of Wisconsins Real-Time Economy Part 3

This week a leading information technology publication named four traditional Wisconsin companies as the best places in America to work in IT. All four placed in the top 50 out of 100. Harley-Davison was ranked number 2, higher than MasterCard, Wal-Mart, Ford, and UPS. American Family Insurance was ranked 22, Lands End 34, and TDS was ranked 40. What do all of these companies have in common? They...

siRNA screening of the cell cycle with two dynamic GFP sensors (from Discovery Matters Issue 1, July 2005)

M. Kenrick, S. Hancock, S. Stubbs, and N. Thomas GE Healthcare, The Maynard Centre, Cardiff, UK Recent advances in siRNA methodologies and the development of high-throughput image analysis platforms such as the IN Cell Analyzer have revolutionized the functional analysis of genes and proteins. Here, we describe the application of...

The Affymetrix GeneChip Scanner 3000 New Advances in Scanner Design for Superior Performance, Reliability, and Dynamic Range

New Advances in Scanner Design for Superior Performance, Reliability, and Dynamic Range platform as an integrated genetic analysis system, supporting continued...

There's a new dynamic in the stem cell debate

, however, is not yet prepared to rule out a new method of deriving stem cells from human embryos that does not...

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Population dynamics

processes influencing those changes....

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Population dynamics

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ESRC offers new dynamics for old in UK

By 2025, the number of people in Britain over the age of 60 will outnumber those under 25. Pressure on both pensions and pensioner spending power will increase. Answers to problems//, old and new, will have to be sought. In a move to address the issues of ageing - one of the most significant aspects of change in our lives, the Economic and Social Research Council (ESRC) is highlighting...

Infections Of The Oral Cavity Can Be Treated By Photodynamic Therapy

Anti-biotic resistant bacterial and fungal infections of the oral cavity can be effectively treated by using photodynamic therapy (PDT)//, argue researchers from the University at Buffalo's School of Dental Medicine. Photodynamic therapy is commonly employed in cancer treatment. PDT is currently employed in the treatment of Kaposi's sarcoma, breast cancer (spread to the chest wall) an...

"Dynamic Energy Landscape" of enzyme in Catalysis

Complex protein molecules called enzymes catalyze specific biochemical reactions in cells. The traditional theory is that dynamic fluctuations//protein conformation or structure play a major role in enzyme catalysis. However, recent findings reveal that it is the "dynamic energy landscape" of the enzyme that directs it to a specific pathway that reduces the number and dimension of the energetic b...

Predicting the Dynamics of Clotting in Human Blood

University of Chicago chemists have demonstrated for the first time how to use a simple laboratory model consisting of only a few chemical reactions to predict when and where blood clotting will occur.// The scientists used microfluidics, a technique that allows them to probe blood clotting on surfaces that mimic vascular damage on the micron scale, a unit of measurement much narrower than the di...

Photodynamic Therapy can Scramble the Immune System to Fight Cancer Spread

A light-triggered cancer treatment called photodynamic therapy (PDT) may be able to treat advanced cancer at the same time as targeting local tumours , according to research published in the British Journal of Cancer today (Tuesday). PDT is a relatively new way of treating cancer, still at an early stage of development and being researched in labs around the world. It uses drugs tha...

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SB Charit Intervertebral Dynamic Disc Spacer

Description:The SB Charit is a prosthesis system consisting of two endplates made of high quality cobalt chromium alloy with an ultra high molecular weight polyethylene sliding core placed between them....
Company:DePuy Orthopaedics, Inc.

PASCAL Dynamic Contour Tonometer

Description:Slitlamp-mounted contact tonometer for precision tonometry (corneal thickness independent)...
Company:ZIEMER USA, Inc.

Xtrem Dynamic electrophysiology catheter

Description:Xtrem Dynamic is a line of steerable diagnosis catheters with micro handle. These catheters have been designed to provide pacing and recording during invasive electrophysiology procedures....
Company:ELA Medical, Inc.

VISULAS 690s Photodynamic Therapy Laser System

Description:The VISULAS 690s is the benchmark for photodynamic therapy. As the instrument of choice for the international phase III Visudyne clinical trials, Carl Zeiss has leveraged its 20 year legacy in laser manufacturing to create the photodynamic therapy laser trusted by the world's leading ophthalmologists....
Company:Carl Zeiss Meditec, Inc.

DJD II Dynamic Elbow Joint Distractor

Description:The two principal goals of the DJD® II are to allow active or passive motion of the elbow and to protect the articular surfaces of the elbow and collateral ligaments. Motion is allowed by a hinge which is designed to replicate the elbow's axis of rotation, while an integrated distraction mechanism prevents the articular surfaces from damaging each other. The DJD® II may be used in either...
Company:Stryker Corporation

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Modigene Announces Successful Completion of Pharmacokinetic & Pharmacodynamic Pre-Clinical Experiments for Proprietary Long-Acting Human Growth Hormone, Long-acting Interferon Beta and Long-acting Erythropoietin

VIENNA, Va., June 20, 2007 /PRNewswire/ -- Modigene Inc., aNevada corporation today announced the successful completion ofpharmacokinetic and pharmacodynamic pre-clinical experiments forlong-acting human growth hormone, long-acting interferon beta andlong-acting erythropoietin. Modigene's pharmacodynamic and pharmacokinetic pre-clinicalexperiments demonstrated superb durability of...