Vein Condition May Mask Serious Clot Disorder

...9 percent had DVT in the other leg and 18 percent had it in both legs, the researchers said. Anybody with SVT should undergo routine screening with duplex ultrasound, which can be performed either in a doctor's office or by a vascular specialist, Lookstein said. The findings were published in the Jul...

B. Braun Anticipates Becoming First to Deliver FDA Approved 2g Cefazolin

... Approval for Antibiotic Delivered in duplex Delivery System Pending BETHLEHEM, Pa., June ...B. Braun will offer 2g Cefazolin delivered via its duplex (R) Delivery System, a ready-to-use two-compart...nd diluent doses. Healthcare workers administering duplex (R) simply squeeze the container and shake it t...

DRE Veterinary Unveils Line of Surgical and Exam Tables

... 300 pounds and has a 22” x 44” stainless steel top. Its frame is constructed of seven-gauge steel, and DRE Veterinary furnishes it with a duplex electric outlet, floor levelers and tie downs. Each DRE VSE Series table includes a five-year warranty, while some table components—such as ...

My1Stop.com Offers Industry Specific Printing, Packing Slip and Labeling Solutions for Warehouse, Fulfillment and Distribution Centers

... and securely order critical supplies ranging from duplex shipping labels and packing slips to integrated la...idest array of options available. The selection of duplex labels and integrated shipping labels is the large...iaro. The eight new distribution supplies are duplex Shipping Label With Packing Slip, Integrated Sheet...

Simpler Test May Be Best for Diagnosing Blood Clots in Leg

...ewer, more expensive test, new research says. European researchers found that 2-point ultrasonography of the leg -- sometimes called compression or duplex ultrasound -- was as good at detecting DVT as the newer, whole-leg, color-coded doppler ultrasound test. "In general, the 2-point approach is safe,...

First look at an enzyme target for antibacterial and cancer drugs

...ugh another, said James Berger, a biochemist and structural biologist who led this research. The enzyme cleaves a double-stranded DNA, passes a second duplex through the break, and then immediately repairs the broken strands. This enables topo II to control the topology of DNA for chromosome segregation and...

duplex in Medical Technology

Use of PressureWire(R) Yields a More Accurate Assessment of Translesion Pressure Gradients in Peripheral Vasculature, Two New Studies Report

...ssment of renal artery stenosis: side-by-side comparison of angiography and duplex ultrasound with pressure gradient measurements," this study of 56 RAS patients reports that diagnoses based on renal angiography and color duplex ultrasound overestimated the severity of RAS by 38 percent and 55 percent c...

Calando Pharmaceuticals Publishes Study Showing Anti-Cancer Effect with Lead RNAi Candidate

...vity were further tested. The best candidate siRNA duplex demonstrated potent reduction of RRM2 protein leve...itro and in vivo. These findings confirm that this duplex is a promising candidate for therapeutic developme... Heidel, Calando's Chief Scientific Officer. "This duplex is powerful in its ability to down-regulate its ta...

Calando Pharmaceuticals Announces Preclinical Efficacy and Safety Data of Targeted, Systemic Delivery of siRNA at AACR Annual Meeting

...LAA-01." The formulation investigated contains Calando's proprietary delivery technology and utilizes RNA interference in cancer cells with an siRNA duplex targeting the M2 subunit of ribonucleotide reductase, a well-established cancer target. This duplex, developed at Calando, demonstrates potent anti-pr...

duplex in Medical Products

ArcticTemp Refrigerator (72 Cubic Ft)

Description:...ty on Parts & Labor and an Additional 4 Year Warranty on Compressor. Also available as a chromatography unit which includes two access ports and one duplex outlet (AT-72C)....
Company:MIDSCI

ArcticTemp Refrigerator (61 Cubic Ft)

Description:...ty on Parts & Labor and an Additional 4 Year Warranty on Compressor. Also available as a chromatography unit which includes two access ports and one duplex outlet (AT-61C)....
Company:MIDSCI

ArcticTemp Refrigerator (69 Cubic Ft)

Description:...ty on Parts & Labor and an Additional 4 Year Warranty on Compressor. Also available as a chromatography unit which includes two access ports and one duplex outlet(AT-69C)....
Company:MIDSCI

ArcticTemp Refrigerator (47 Cubic Ft)

Description:...ty on Parts & Labor and an Additional 4 Year Warranty on Compressor. Also available as a chromatography unit which includes two access ports and one duplex outlet (AT-47C)....
Company:MIDSCI

ArcticTemp Refrigerator (49 Cubic Ft)

Description:...ty on Parts & Labor and an Additional 4 Year Warranty on Compressor. Also available as a chromatography unit which includes two access ports and one duplex outlet (AT-23C)...
Company:MIDSCI

ArcticTemp Refrigerator (33 Cubic Ft)

Description:...ty on Parts & Labor and an Additional 4 Year Warranty on Compressor. Also available as a chromatography unit which includes two access ports and one duplex outlet (AT-33C)....
Company:MIDSCI

duplex in Medical Dictionary

Blood flow studies

...methods for performing blood flow studies . A duplex study uses Doppler ultrasound to measure bloo...methods for performing blood flow studies . A duplex study uses Doppler ultrasound to measure bloo...methods for performing blood flow studies . A duplex study uses Doppler ultrasound to measure bloo...

duplex in Biological News

Triplex assay used to assay duplex genomic DNA

Direct detection of base sequence in duplex nucleic acid has long been an unfulfilled objective. Ingeneus Research will publish "Heteropolymeric Triplex-Based Genomic Assay® to Detect Pathogens or Single-Nucleotide Polymorphisms in Human Genomic Samples" in the March 21st issue of the international...

Strong immune response to new siRNA drugs in development may cause toxic side effects

...iewed journal published by Mary Ann Liebert, Inc. (www.liebertpub.com) The article is available free online at www.liebertpub.com/oli siRNAs are duplex structures comprised of short oligonucleotide sequences. The discovery that naturally occurring and synthetic siRNAs can effectively prevent expressio...

Liquid crystal phases of tiny DNA molecules point up new scenario for first life on Earth

...in spite of having almost no elongation in shape. Structural analysis of the liquid crystal phases showed that they appeared because such short DNA duplex pairs were able to stick together end-to-end, forming rod-shaped aggregates that could then behave like much longer segments of DNA. The sticking was...

Stability of mRNA/DNA and DNA/DNA duplexes modulates mRNA transcription

...ce can simultaneously encode its respective protein and modulate its level of expression." says Stoynov. The mechanism of how DNA/DNA and mRNA/DNA duplex stability influences mRNA level remains unclear. The authors propose two models, but further work is needed to understand how thermodynamic stability ...

Clearing jams in copy machinery

...n add, in assembly line fashion, nucleotide bases -- the building blocks that make up DNA -- to convert the now-single-stranded templates into two new duplex DNA molecules. The new research shows that two different DNA polymerases, the high fidelity Pol III replicase and the low fidelity Pol IV, coordina...

Health costs soar as 60 million Americans classed as obese

...nois at Urbana-Champaign. The technique uses double-stranded DNA to direct the behavior of other molecules. In previous DNA nanotechnology efforts, duplex DNA has been used as a static lattice to construct geometrical objects in three dimensions. Instead of manipulating DNA alone into such shapes, the re...

duplex in Biological Technology

Nastech Assigns Intellectual Property Related to the Development of RNA-Based Therapeutics to its Subsidiary, MDRNA, Inc.

...lar Delivery dsRNA -- Compositions and Methods Employing Universal-Binding Nucleotides for Targeting Multiple Gene Variants with a Single siRNA duplex -- RNAi Therapeutic for Respiratory Virus Infection -- Compositions and Methods for Complexes of Nucleic Acids and Peptides -- Phage Displayed C...

Evaluation of FlashPlate in a Helicase Assay

... to each other, to form a [ 33 P]-biotinylated DNA duplex substrate, then immobilized on the SMP103 FlashPla...mperature. 3. Approximately 1 ng of DNA duplex was applied to each well of the SMP103 FlashPlate ... In the presence of ATP, double stranded DNA duplex can be unwound by T-Antigen (0.7 μg) beginnin...

A Multiple Mutation Model System as a Test Development and Training Tool for Denaturing Gradient Gel Electrophoresis

...ent the strands begin to melt. The melting profile of a given DNA duplex is predominantly determined by its base sequence with greater GC ..., T and Lerman, L. S., Modification of the melting properties of duplex DNA by attachment of a GC-rich DNA sequence as determined by den...

RNA Interference and Gene Silencing: History and Overview

...d to a nuclease complex to form what is known as the RNA-induced silencing complex, or RISC. An ATP-depending unwinding of the siRNA duplex is required for activation of the RISC. The active RISC then targets the homologous transcript by base pairing interactions and clea...

siRNA Design: It's All in the Algorithm

...ed. In fact, siRNAs with high duplex stability at one end and low duplex stability at the other exhibi... can unwind the first 4-5 nucleotides of the duplex (Figure 5). These findings he...

Precursor miRNAs for Successful miRNA Functional Studies

...(or siRNA) pathway [11] (the other strand is referred to as the "off-strand"). The sequence compositions and duplex stabilities of the small RNA molecules dictate the strand that will be active in the cell. Transfected miRNAs ...

duplex in Biological Products

21-mer duplex from B-Bridge International

Description: siSolutions siRNA Custom Synthesis Service provides you with high-quality, effective duplex RNA to knockdown any gene. We offer standard 21-mers (19 RNA base pairs with terminal dT nucleotides), the recently-published 27-mers, or other lengths of your choice. Each individual sequence includes quali...
Company:B-Bridge International

27-mer duplex from B-Bridge International

Description: siSolutions siRNA Custom Synthesis Service provides you with high-quality, effective duplex RNA to knockdown any gene. We offer standard 21-mers (19 RNA base pairs with terminal dT nucleotides), the recently-published 27-mers, or other lengths of your choice. Each individual sequence includes quali...
Company:B-Bridge International

21-mer duplex design + syn.; 1 gene from B-Bridge International

Description: siSolutions siRNA Custom Synthesis Service provides you with high-quality, effective duplex RNA to knockdown any gene. We offer standard 21-mers (19 RNA base pairs with terminal dT nucleotides), the recently-published 27-mers, or other lengths of your choice. Each individual sequence includes quali...
Company:B-Bridge International

3x 21-mer duplex design + syn.; 1 gene from B-Bridge International

Description: siSolutions siRNA Custom Synthesis Service provides you with high-quality, effective duplex RNA to knockdown any gene. We offer standard 21-mers (19 RNA base pairs with terminal dT nucleotides), the recently-published 27-mers, or other lengths of your choice. Each individual sequence includes quali...
Company:B-Bridge International

TRIMMER-Direct cDNA Normalization Kit from Evrogen JSC

Description:...ws to obtain normalized cDNA samples in which individual cDNA sizes range from 0.5 to 4.5 kb. The normalization is based on unique properties of novel duplex Specific Nuclease (Zhulidov et al., Nucl. Acids. Res. 2004, 32: e37). It is performed prior to cDNA cloning, and does not include physical separation ...
Company:Evrogen JSC

siSolutions RNAi Services from B-Bridge International

Description:...oward the target gene, while minimizing off-target effects. They can design duplex siRNA for human, mouse, rat or any species of your choice. For your conveni...ns siRNA Custom Synthesis Service provides you with high-quality, effective duplex RNA to knockdown any gene. They offer standard 21-mers (19 RNA base pairs w...
Company:B-Bridge International

duplex in Biological Dictionary

UvrA

...anking ... Reported regulatory sites for uvrA : Genome coordinates. Source. Transcription factor ... Furthermore, the TFO was dissociated from its duplex binding site by UvrA and UvrB. ... In this process, dimerized UvrA binds UvrB in a search for damage-induced ... The UvrA protein is the ...

Transfection

...... DOTAP Liposomal Transfection Reagent ... Find a range of specialized transfection reagents that effectively deliver plasmid DNA, siRNA or duplex RNAi, oligonucleotides, and RNA into eukaryotic cells for a ... More information on Cutting Edge Transfection Reagents from Roche Applied Scien...

SiRNA

...active they are. Two types of small RNA molecules – microRNA (miRNA) and small interfering RNA ( siRNA ) – are central... At some point the siRNA duplex unwinds, and it appears that the antisense strand ... siRNA technology is now extensively recognized as a powerful tool for the ... Describes...

RNA polymerase

...ion about RNA polymerase in the free ... A polymerase that catalyzes the synthesis of a ... RNA polymerase requires DNA as a template. In duplex DNA, the template ... RNA polymerase catalyzes the sequential addition of a ribonucleotide to the 3' ... Though several different types of R...

Renal arteries

...al Artery Stenosis (Magnetic Resonance Angiography) ... Review Article from The New England Journal of Medicine -- Renal - Artery Stenosis ... duplex Imaging of the Renal Arteries with Contrast Enhancement. ... about an 82-year-old woman with hypertension and renal artery stenosis. SYMPTO...

Recombinant DNA molecule

...tific discoveries were required before the manipulation and propagation of engineered DNA molecules could be undertaken. Molecules of linear, duplex DNA (which are believed to migrate in an end-on ... The shape of the DNA molecule . ... Recombinant DNA Tutorials (Cornell Univ. ... " Rec...