Triplex assay used to assay duplex genomic DNA
Direct detection of base sequence in duplex nucleic acid has long been an unfulfilled objective. Ingeneus Research will publish "Heteropolymeric Triplex-Based Genomic Assay® to Detect Pathogens or Single-Nucleotide Polymorphisms in Human Genomic Samples" in the March 21st issue of the international, peer-reviewed, open access, online journal, PLoS ONE. In the article they present a wealth...Stability of mRNA/DNA and DNA/DNA duplexes modulates mRNA transcription
The distribution of the four nucleotides along the DNA sequence encodes the genetic information in living systems. However, do nucleic acids possess other attributes that contribute to their biological functions? Recent work of a team led by Stoyno Stoynov, working at the Bulgarian Academy of Sciences, suggests that thermodynamic stability of DNA/DNA and RNA/DNA duplexes influences mRNA transcrip...3x 21-mer duplex design + syn.; 1 gene from B-Bridge International
Description:siSolutions siRNA Custom Synthesis Service provides you with high-quality, effective duplex RNA to knockdown any gene. We offer standard 21-mers (19 RNA base pairs with terminal dT nucleotides), the recently-published 27-mers, or other lengths of your choice. Each individual sequence includes quality control data with gel images....21-mer duplex design + syn.; 1 gene from B-Bridge International
Description:siSolutions siRNA Custom Synthesis Service provides you with high-quality, effective duplex RNA to knockdown any gene. We offer standard 21-mers (19 RNA base pairs with terminal dT nucleotides), the recently-published 27-mers, or other lengths of your choice. Each individual sequence includes quality control data with gel images....27-mer duplex from B-Bridge International
Description:siSolutions siRNA Custom Synthesis Service provides you with high-quality, effective duplex RNA to knockdown any gene. We offer standard 21-mers (19 RNA base pairs with terminal dT nucleotides), the recently-published 27-mers, or other lengths of your choice. Each individual sequence includes quality control data with gel images....21-mer duplex from B-Bridge International
Description:siSolutions siRNA Custom Synthesis Service provides you with high-quality, effective duplex RNA to knockdown any gene. We offer standard 21-mers (19 RNA base pairs with terminal dT nucleotides), the recently-published 27-mers, or other lengths of your choice. Each individual sequence includes quality control data with gel images....Heteroduplex Analysis Using the DCode System
Bio-Rad Laboratories, Hercules, California Heteroduplex Analysis (HA) is a commonly used mutation screening method due to its simplicity. The technique is based on conformational differences in double-stranded DNA caused by the formation of hete...