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Purdue proves concept of using nano-materials for drug discovery

Researchers at Purdue University have built and demonstrated a prototype for a new class of miniature devices to study synthetic cell membranes in an effort to speed the discovery of new drugs for a variety of diseases, including cancer. The researchers created a chip about one centimeter square that holds thousands of tiny vessels sitting on top of a material that contains numerous pores...

Purdue researchers use enzyme to clip 'DNA wires'

Researchers at Purdue University have attached magnetic "nanoparticles" to DNA and then cut these "DNA wires" into pieces, offering the promise of creating low-cost, self-assembling devices for future computers. Findings are detailed in a paper published online in February in the Journal of the American Chemical Society. The paper was written by Purdue graduate student Joseph M. Kinsella...

Purdue scientists may have found key to halting spinal cord damage

Purdue University researchers may have isolated the substance most responsible for the tissue damage that follows initial spinal cord injury, a discovery that could also improve treatments for a host of other neurodegenerative conditions. A research team led by Riyi Shi (REE-yee SHEE) has found that a chemical called acrolein, a known carcinogen, is present at high levels in spinal tissue...

Fluoride poisoning in China due to clay, not coal

Millions of people in southwest China suffer from potentially-crippling fluoride poisoning because they burn a mixture of clay and coal, say researchers. Because of this belief, last year, the...

Purdue researchers find key to rice blast fungus

Efforts to halt a fungus that deprives about 60 million people a year of food have led Purdue University scientists to discover the molecular machinery that enables the pathogen to blast its way into rice plants. The fungus, Magnaporthe grisea, which is known as rice blast fungus, is the most deadly of the pathogens that attack rice, reducing yields by as much as 75 percent in infected ar...

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due at Biology Products

LIC Duet™ Minimal Adaptor from Novagen

Description:The LIC Duet™ Mini Adaptor encodes a T7 promoter, operator, ribosome binding site (rbs), and an ATG translation initation codon. This adaptor is designed for expression of a target protein with minimal vector-encoded fusion sequences....
Company:Novagen

LIC Duet™ T7•Tag^® Ek Adaptor from Novagen

Description:The LIC Duet™ T7•Tag operator, ribosome binding site (rbs), ATG translation initation codon, and an N-terminal T7•Tag coding sequence. The T7•Tag is a small epitope tag (11 aa) that is useful for detection of the target protein with T7•Tag Monoclonal Antibody and purification using the T7•Tag Affinity Puri...
Company:Novagen

LIC Duet™ GST•Tag™ Ek Adaptor from Novagen

Description:The LIC Duet™ GST•Tag™ Ek Adaptor encodes a T7 promoter, operator, ribosome binding site (rbs), ATG translation initation codon and an N-terminal GST•Tag coding sequence. The GST•Tag sequence has been reported to enhance the production and in some cases the solubility of its fusion partners. The GST•Tag is a multi-purpose tag that can be used for purific...
Company:Novagen

LIC Duet™ Trx•Tag™ Ek Adaptor from Novagen

Description:The LIC Duet™ Trx•Tag™ Ek Adaptor encodes a T7 promoter, E. coli</i...
Company:Novagen

pETDuet-1 from Novagen

Description:pETDuet-1 is designed for the coexpression of two target genes....
Company:Novagen

due at Biology Technology

Fast Multi-Residue Pesticide Analysis in Soil and Vegetable Samples

The strict detection limits that are required for the quantitation of pesticide residues in food and environmental samples requires the use of very sensitive, selective, and rugged LC/MS/MS technologies. In this application note the benefits of using LC/MS/MS for this type of analysis...

Simultaneous Determination of Residues of Approximately 100 Pesticides and Metabolites in Fruit and Vegetables by LC/MS/MS

Many pesticides, which are difficult or generally not to analyse by GC/MS, can be identified and quantified by LC/MS/MS. After simple solvent extraction and fast cleanup the extracts are analysed using matrix-matched standards. The drawback of MS/MS methods is laborious parameter optimization for each target analyte. This effort can...

Determination of the Chloramphenicol residues in milk and milk products using LC/MS/MS

The European Union prohibits the use of chloramphenicol (CAP) as a veterinary drug for food producing animals. For this reason a rapid and sensitive confirmatory method for the identification and quantification of CAP in milk and milk products has been developed using the API 3000 LC/MS/MS System. Although many analytical procedures are describ...

Due diligence and corporate clean-up

As outlined in ", when raising equity capital, one of the first things a company should do is prepare a business plan. The business plan often forms the centerpiece of the private placement memorandum (PPM), the disclosure document that is typically circulated to inves...

due at Biology Dictionary

Residue

Numerous s in α-helices typically adopt bac...

due at Medicine News

Epileptic Seizures Can Be Duec to Heart Problem

British researchers have said that Many people thought to have epilepsy may have a heart problem instead. In a study, researchers closely examined people diagnosed with epilepsy who did not respond well to medication or had symptoms unusual for the disorder. They found that more than 40% had another medical problem--most often a heart or circulation condition--that could have caused the s...

Death due to premature heartbeat after exercise

Frequent ventricular ectopy, another name for premature heart beat, during recovery after exercise has been found by researchers to be a better predictor of an increased risk of death and one that occurs during exercise. Doctors from Cleveland Clinic Foundation observed 29,244 patients with no history of heart failure, valve disease or arrhythmia. They were referred to an exercise test to...

Toni Braxton Can’t Have More Kids Due to Pericarditi

London: Rich and famous celebrity soul music singer Toni Braxton wants a baby girl, but is afraid her heart might not be able to cope with a third Toni Braxton as she has pericarditis//. Since giving birth to her second son with husband Keri Lewis in 2003, Braxton has been diagnosed with pericarditis - a potentially fatal heart condition. She fears the condition will kill her if she pl...

Delhi Faces Flu Threat Due To Change In Weather

Seasonal illnesses like that of viral flu are spreading across Delhi with the reversal of the cold wave conditions. While Delhi recorded a minimum of 0.2 degrees Celsius (7 degrees below normal) on 8 January, just over a week later the temperature reached 11.6 degrees //(five degree above normal) on 17 January 2006. Doctors have called upon people to be careful about the weather change....

Measles Resurges Due To Drop In Immunization With MMR

The fall in number of children getting the MMR (combined Measles, Mumps &Rubella) vaccine by their parents has been blamed for the resurgence of measles that has claimed the life of a 13-year-old boy. // In the first three months of 2006 alone it is found that there are more people infected than the whole of 2005. At least 30 children have caught measles in a single outbreak in South Y...

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due at Medicine Products

Selecta Duet

Description:Selecta Duet is the unique combination laser system for glaucoma and cataract treatments. At the touch of a button switch between SLT or Nd:YAG mode on the remote control. The Selecta Duet affords you the opportunity to treat a wider array of patients, in the same setting with the benefits inherent to laser surgery at a manageable cost....
Company:Lumenis Inc.

Duet Lumbar Allograft System

Description:Duet Lumbar Allografts are comprised of a raised cancellous inner core providing biomechanical properties for rapid healing. Specially designed instruments facilitate the insertion of Duet Allografts....
Company:Alphatec Spine, Inc.

e.cam ^duet

Description:The e.cam Signature Series multipurpose gamma camera is designed for SPECT and PET FDG imaging applications. The system uniquely combines the high-energy and PET imaging capability with the features and flexibility of modern day SPECT and planar imaging, all in one unit.The e.cam duet maximizes camera performance in PET and general nuclear medicine applications well beyond...
Company:Siemens Medical Solutions USA, Inc.

Duett

Description:The Duett sealing device is used to seal the arterial puncture site. Duett is the only sealing device to seal both the arteriotomy and the tissue tract with a flowable procoagulant. Using a dual approach - a balloon catheter and procoagulant - the Duett sealing device is designed to rapidly and safely stop the bleeding. The Duett is unique in its ability to quickly seal the entire puncture site...
Company:Vascular Solutions, Inc.

Duett Pro.

Description:The Duett Pro is simple, precise and efficient. Duett Pro sleeve hub is lightweight and ergonomic. A 'quick connect' feature provides a secure connection of the sleeve hub to the base during catheter deployment....
Company:Vascular Solutions, Inc.

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due at Medicine Technology

FDA Announces Results of Investigation Into Illegal Promotion of OxyContin by The Purdue Frederick Company, Inc.

Company Misrepresented Prescription PainReliever to Health Care Professionals ROCKVILLE, Md., May 10, 2007-The U.S. Food and DrugAdministration's (FDA) Office of Criminal Investigations (OCI)announced today that The Purdue Frederick Company, Inc. has agreedto pay more than $700 million to resolve criminal charges and civilliabilities in connection with...

Increasing Proportion of Cardiovascular Disease Due to Diabetes Over the Last 50 Years

BETHESDA, Md., March 27, 2007--A new study shows that as ratesof diabetes have risen in the U.S., the proportion ofcardiovascular disease (CVD) linked to diabetes has alsoincreased. These findings emphasize the need for increased efforts toprevent diabetes and to aggressively treat and control CVD riskfactors among those with diabetes, according to the investigatorsfrom the long-s...