Controversial drug shown to act on brain protein to cut alcohol use
Medicationagainst nicotine addiction is nowadays readily available. However, asimilar and equally dangerous addiction, alcoholism, can't yet becontrolled by drugs. Or can it be? Researchers from the University ofCalifornia in San Diego identified a natural compound able to blockalcohol addiction in rodents. We can only hope that anti-alcoholismpatchs or gum...Drug That 'Tags' Decision-making Areas Of The Brain May Aid
Along with aiding efforts to study addictedsmokers, a new drug that attaches only to areas of the brain that havebeen implicated in may help studies of people battling other disorders such as Alzheimer’sdisease and schizophrenia.Developed by UC Irvine Transdisciplinary Tobacco Use Research Centers...Computers to be used to find blueprint for new influenza drug
Researchers at the University of Bath have won a £261,000 grant to use the latest software to produce a blueprint of a designer drug that could stop influenza and some other diseases from replicating in humans. Professor Ian...HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs
A widely-used class of drugs that keep the HIV-virus infection from progressing to AIDS may cause serious and potentially lethal heart rhythm disturbances in some patients. The finding of a Mayo Clinic-led investigation appears in the current edition of The Lancet. In collaboration with colleagues from the HIV Program of Hennepin County Medical Center, Minneapolis; the University of Minn...SkanIt Software for Varioskan, Drug Discovery Edition from Thermo Scientific
Description:SkanIt Software is the ultimate tool for both microplate reader control and data handling. There are two editions of SkanIt Software available; a Research Edition for scientists working in life science research, and a Drug Discovery Edition offering features needed for compliance with FDA's 21 CFR Part 11, for the drug discovery industry....FDSS6000 System from Hamamatsu Photonic Systems - Drug Discovery
Description:The FDSS6000 System is an imaging based plate reader for cellular assays, assay development and high throughput screening which can utilize both fluorescence and luminescence modalities. The Hamamatsu light sources and cameras in the FDSS6000 highlight our companys decades-long experience in photon detection technology. It is a modular, upgradable, and fully integrated system. Versa...LabChip 3000 Drug Discovery System from Caliper Life Sciences
Description:The LabChip 3000 drug discovery system miniaturizes, integrates and automates enzymatic and cell-based assays. Using LabChip technology, the LabChip 3000 performs screening experiments in a serial, continuous flow fashion. LabChip assays are separations-based, so the quality of results exceeds what is achievable in homogenous, well-based assays. No other screening system identifies weak enzyme...HIV Volume 2 (Biochemistry, Molecular Biology and Drug Discovery) from Promega
Description:J. Karn (1995) This volume provides excellent background information, detailed practical information and methods for the study of major HIV proteins including: the HIV growth cycle; reverse transcriptase, ribonuclease H, integrase and protease. Expression of HIV proteins using baculoviruses; RNA binding assays; Tat and Rev assays; HIV/CD4 interactions; transient assays for Nef-induced down regu...High-throughput gene expression analysis to screen for anti-asthma drugs
Andreas Pahl, Uwe Oelmller,* and Susanne Ullmann Department of Pharmacology, University of Erlangen, Erlangen, Germany * QIAGEN GmbH, Hilden Germany Drug library screening based on gene expression analysis requires reliable and reproducible methods of RNA pu...Drug innovation beats marketing, patents and mergers
While Genentech had revenues of $4.6 b...Exploiting the Life Science Data Explosion to Speed New Drug Discovery
This paper discusses key problems and opportunities created by the explosion in both the degree (volume) and complexity of life science data available today, and presents a strategic and technological approach to data integration that enables r...Simultaneous Screening of 23 Drugs of Abuse in Oral Fluid Using an LC/MS/MS Method
They are not as commonly available for novel sample matrices such as saliva as...New Drug in Diabetic Neuropathy
Diabetic Neuropathy can be a painful condition which is a very agonizing nighttime pain seen in diabetics. However, new hope lies with experimental drug, memantine, which blocks NMDA receptors, which are believed to mediate pain effects in diabetic neuropathy being researched by Central Arkansas Research, Arkansas. This drug showed a definite reduction of pain compared to placebo....Lean Protein Could Be Key to Obesity Drugs
A protein that lets mice eat more but weigh less could prove the magic ingredient for diet drugs of the future.British scientists from drug giant SmithKline Beecham and the University of Cambridge have created mice with a human protein known as Uncoupling Protein 3 (UCP3) that increases their metabolism.In what is every dieter's dream, the mice were able to eat more than normal mice but s...Drug May Make Breathing Easier for Millions
An experimental drug could make millions of people suffering from smoker’s lung breathe much easier. Chronic Obstructive Pulmonary Disease (COPD) or smoker’s lung, is an irreversible progressive illness caused by narrowing of the airways. It encompasses emphysema and chronic bronchitis. In tests involving 500 people who had suffered from COPD for more than a decade, the drug appeared...Life Saving Cancer Drugs – From Chicken! Possible Says 'Dolly’ Creatos
In what can be a watershed in cancer research, Scottish scientists along with US Biotech Company Viragen Inc., have used nuclear transfer technology to harvest life saving drugs to treat many serious diseases including cancer. The same team had earlier cornered world wide fame and glory (and a lot of criticism!) for creating Dolly – the world’s first cloned mammal: Using the same nuclear...QuickScreen™ At Home Drug Test
Description:The QuickScreen™ At Home Drug Test is the first rapid drug test kit cleared by the FDA for home use. The kit includes a rapid drug-screening device, a wide-mouth collection container, easy to read instructions, a handbook with frequently asked questions and all the materials needed to ship the sample to the laboratory if the screening device indicates the presence of drugs in the sample....SureStep™ Drug Screen Tests - One-Step Immunoassays (Morphine II)
Description:The SureStep™ Drug Screen Tests are available in 14 configurations including the newest assay for MDMA (Ecstasy). Designed using Microgenics Antibody Technology, the SureStep™ MDMA (Ecstasy) test is the only point of care immunoassay targeted to detect MDMA that has an affinity for both MDA and MDEA but no cross-reactivity to any isomer of methamphetamine or amphetamine.The SureStep&t...SureStep™ Drug Screen Tests - One-Step Immunoassays (Morphine)
Description:The SureStep™ Drug Screen Tests are available in 14 configurations including the newest assay for MDMA (Ecstasy). Designed using Microgenics Antibody Technology, the SureStep™ MDMA (Ecstasy) test is the only point of care immunoassay targeted to detect MDMA that has an affinity for both MDA and MDEA but no cross-reactivity to any isomer of methamphetamine or amphetamine.The SureStep&t...SureStep™ Drug Screen Tests - One-Step Immunoassays (Cocaine)
Description:The SureStep™ Drug Screen Tests are available in 14 configurations including the newest assay for MDMA (Ecstasy). Designed using Microgenics Antibody Technology, the SureStep™ MDMA (Ecstasy) test is the only point of care immunoassay targeted to detect MDMA that has an affinity for both MDA and MDEA but no cross-reactivity to any isomer of methamphetamine or amphetamine.The SureStep&t...Monitoring Options Expand for Therapeutic Agents and Drugs of Abuse
In keeping with the recent proliferation of rapid, easy-to-use diagnostic tests, many assays and collection products have entered the marketplace to help clinicians assess dosage appropriateness of therapeutic drugs and to screen for the presence of drugs of abuse. Some of these products require laboratory support while many simple test kits are suitable for point of care use by medical profe...Samaritan's Alzheimer's Drug Caprospinol Suggests Brain May be Able to Heal From Alzheimer's Disease
Animal Study Confirms Caprospinol's (SP-233) Ability to Clear BrainPlaque and Empower Rat Brain Cells to Recover Memory Function In Vivo 'Proof of Concept' Study Proposes Direct CorrelationBetween Removing Beta Amyloid Plaque and Memory Recovery LAS VEGAS, July 10, 2007 (PRIME NEWSWIRE) -- SamaritanPharmaceuticals Inc. (AMEX:LIV), a developer of innovative drugs,is ple...New Drugs in Multinational Study Show Promise in Fighting Drug-Resistant HIV
Phase III clinical trial provides hope that HIV patients can livelonger lives PASADENA, Calif., July 05, 2007 /PRNewswire/ -- A newinvestigational drug used in combination with a second newer agenthas proven to be effective in fighting drug-resistant HIV,according to a Lancet article to be published in its July 7thspecial HIV/AIDS issue. The multinational phase III clinical trial,...Clinical Data From Nymox BPH Drug To Be Presented at American Urological Association Meeting
HASBROUCK HEIGHTS, N.J.--(BUSINESS WIRE)--Jul 3, 2007 - NymoxPharmaceutical Corporation (NASDAQ: NYMX) today announced thatfurther clinical results from the Company's studies of NX-1207 forbenign prostatic hyperplasia (BPH) will be presented at the NewEngland Section of the American Urological Association Meeting inBoston in September. The paper is authored by leading clinicalresearch inves...Nonsteroidal anti-inflammatory drugs
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