Down

Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down

For patients with high-risk breast cancer treated with radical mastectomy and adjuvant chemotherapy, the addition of radiation therapy leads to better survival outcomes with few long-term toxic effects, according to a 20-year follow-up of a randomized trial, which appears in the January 19 issue of the Journal of the National Cancer Institute. The British Columbia randomized radiation the...

Growth in the sea comes down to a struggle for iron

Scientists know that injecting iron into some major regions of the oceans can stimulate the growth of diatoms and other phytoplankton, but something odd occurs as these tiny marine plants continue to grow. They begin to starve in the midst of plenty, acting as though iron, an essential nutrient, still is in short supply. Why this happens is unclear, but the answer could be that iron sets off a ki...

Learning to fight an adversary that won't stay down

New biomolecular technologies have largely failed to deliver the hoped-for knockout punch breakthrough against the defences of disease-causing bacteria, says a leading Canadian specialist in antibiotic resistance. Techniques such as genomic sequencing and high throughput screening were expected to make the development of new antibiotic compounds easier and more productive. But in most cas...

Shutting down the HIV assembly line

After infecting a susceptible cell, the human immunodeficiency virus hijacks that cell's normal machinery to produce carbon copies of itself. New HIV particles roll off the cellular assembly lines, burst like bubbles out of the cell, and float off to invade other cellular factories. Vanderbilt University Medical Center investigators have now identified an early step in HIV particle assembly. The...

Venom doc tracks down snake bioweapons

Bryan Grieg Fry, Ph.D., a scientist from the University of Melbourne, Australia, has conducted the first comprehensive analysis of the origin and evolution of one of nature's most sophisticated bioweapons: snake venom. His results are reported in the March issue of the journal Genome Research. Venomous snakes, all of which belong to the superfamily Colubroidea, evolved glands for the stora...

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Down Draft Work Station from Terra Universal, Inc.

Description:Ideal for chemical processing that requires downward flow of exhaust fumes. Powderful 1200 CFM blower draws fumes into sub-surface bonded charcoal filter for safe removal of organic vapors (final HEPA filter also available)....
Company:Terra Universal, Inc.

ANTIGEN-DOWN ASSAY DILUENT from AbD Serotec

Description:Form: Ready to use Applications: ELISA...
Company:AbD Serotec

Down at Biology Technology

Measuring siRNA-mediated knockdown of IL-8 mRNA

By Genospectra, Inc., 6519 Dumbarton Circle, Fremont, CA 94555. A critical step in siRNA-mediated gene expression knockdown studies is the validation of expression inhibition. The QuantiGene Reagent System and the Molecular Devices LMax II microplate luminometer were used to measure IL-8 mRNA in PMA-induced HeLa cells, following siRNA t...

Housekeeping Genes: Universal Positive Controls in siRNA Knockdown Experiments

RNA interference is a powerful technique for geneknockdown experiments in academic research and animportant tool for target identification and target validationin therapeutic research. A growing number of different cell lines are us...

Reagents for Up and Down-Regulation of miRNA Activity in Mammalian Cells

More than 200 miRNAs have been cloned and sequenced from human and mouse samples. Each miRNA apparently regulates multiple genes, and miRNAs are thought to regulate as many as 10% of human genes [1]. Several reports predict mR...

Breaking down Wisconsin's angel capital numbers

The figures were outlined in a recent report titled Risk Capital in Wisconsin: A Progress Report for 2006, which was produced by NorthStar Economic...

Doyle wants sales tax applied to digital downloads

The proposed tax, put forth two years after a similar proposal died at the committee le...

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Down at Biology Definition

Mutational meltdown

and decline of the population size, which leads to further accumulation of deleterious mutations. A population experiencing mutational...

Down syndrome

) encompasses a number of...

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Downstream

dow...

Down at Medicine News

Cut down TV and video games and you have less aggressive children.

Have you ever wondered why your kids are so aggressive and almost impossible to handle at times? Then read on. World over there is increasing concern over the way the children of today are growing up. Even the West is getting desperate and looking for help. Things are no better in India. With the TV boom and the IT revolution, the kids seem to know all at a very young age and many parent...

Hormone treatment helps obese people slim down

Treatment with leptin, a natural hormone that helps control body weight, could help many overweight people slim down. Discovered in 1994, leptin is normally produced by fat cells and is believed to provide a signal about the amount of body fat to the body's energy-regulation system. // Leptin treatment has already helped people who completely lack the hormone because of a genetic muta...

Early Clue to Down Syndrome

Down syndrome, also known as trisomy 21, is a chromosomal disorder occurring in roughly one in every 800 live births. The condition produces varying degrees of mental retardation and a range of physical deformities, including a small nose and thick neck, which are detectable more or less in early pregnancy. Detecting Down syndrome early in pregnancy could be as plain as the nose on the ba...

Cut down on fries

A research suggests, that starting the day with a heavy breakfast and a steaming cup of tea may increase a woman's risk of throat cancer.Scientists found that women who eat fried food each morning are at twice the risk of the most common form of throat, or oesophageal, cancer.The best way to reduce the incidence of cancer is to begin the day with a light breakfast such as cereal or fruit...

Down syndrome life anticipation doubles

According to a new study, people with Down syndrome live twice as long today as they did in the early 1980s'. These patients have a lower than average risk of developing many forms of cancer. The study by Quanhe Yang and colleagues published in this week's Lancet was based on data collected from death certificates between 1980 and 1995 in the US.// The researchers found that the averag...

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Full Handle Laseredge Crescent Blade Knife, angled bevel down

Description:Full Handle Laseredge Crescent Blade Knife, angled bevel down. Blade tip dimension: 12.7 mm x 2.0 mm x 3.8 mm....
Company:Bausch & Lomb Storz

Sandown chair

Description:Sandown chair, with hydraulic lift, sliding headrest and armrests with glides. Black vinyl....
Company:Clement Clarke International

Hudson-Downs Burr

Description:...
Company:AESCULAP

Mc Kenzie-Downs Burr

Description:...
Company:AESCULAP

Hudson Downs

Description:Hudson Downs hand drill....
Company:AESCULAP

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Fragile X, Down Syndromes Linked to Faulty Brain Communication, Stanford Researcher Finds

STANFORD, Calif.--(BUSINESS WIRE)--Apr 10, 2007 - The two mostprevalent forms of genetic mental retardation, Fragile X and Downsyndromes, may share a common cause, according to researchers atStanford University School of Medicine. The problem, a crippledcommunication network in the brain, may also be associated withautism. Although the genetics of the disorders are very different, theend...

Down at Medicine Dictionary

Down syndrome

, characteristic facial features and, often, <a href="/ ?q=/ Medicine-Dictio...