Double

It's not all genetic: Common epigenetic problem doubles cancer risk in mice

In experiments with mice, a team of scientists from the United States, Sweden and Japan has discovered that having a double dose of one protein is sufficient to change the normal balance of cells within the lining of the colon, thereby doubling the risk that a cancer-causing genetic mutation will trigger a tumor there. Roughly 10 percent of people have this double protein dose as well. In...

Affymetrix Unveils Plans to Double Plant and Animal Genome Microarray Offering

Sacramento - Today, Affymetrix, Inc.announced plans to make eight new GeneChip(R) plant and animal genomearrays available in 2005 as part of its Consortia Program, includingcanine, Rhesus macaque, Medicago trancatula (legume), Brassica, tomato,citrus, poplar and sugar cane. More than 20 research presentations atthis week's Plant and Animal Genome Conference XIII in San Diego,Calif. feature...

Double triumph in stem cell quest

WITH great fanfare a South Korean team announced last week that it had used therapeutic cloning to create human embryonic stem cells that were genetically matched to specific people. But their technique could already be obsolete. Another team headed by Yuri Verlinsky of the Reproductive Genetics Institute, based in Chicago, claims to have produced patient-matched embryonic stem cells without reso...

Specialized immune-system B cells play double-barreled role

A specialized subpopulation of the antibody-producing B cells of the immune system plays a "double-barreled" role in triggering both kinds of immunity -- innate and acquired, Duke University Medical Center immunologists have discovered. The division of labor between B-1a and B-1b cells they have uncovered offers basic insights that could contribute to more rational development of vaccines, they s...

Double trouble: Cells with duplicate genomes can trigger tumors

Abnormal cell division that yields cells with an extra set of chromosomes can initiate the development of tumors in mice, researchers at Dana-Farber Cancer Institute have shown, validating a controversial theory about cancer causation put forth by a scientific visionary nearly 100 years ago. The so-called "double-value" cells are produced by random errors in cell division that occur with u...

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PicTure - Double Staining Kit from Invitrogen

Description:Double staining is a technique used to reveal two distinct antigens in a single tissue.(1-6) PicTure™-Double Staining Kit is a Zymed polymer double staining detection method for detecting two antigens simultaneously in the same human cell or tissue sample with increased sensitivity. The antigens can be identified using two different primary antibodies from mouse (or rat) and rabbit (or guin...
Company:Invitrogen

Double labelled probes from Thermo Scientific

Description:Double labelled probes are purified either by HPLC or PAGE, depending on the dye combinations....
Company:Thermo Scientific

EnVision™ G|2 Doublestain System, Rabbit/Mouse (DAB+/Permanent Red) from Dako

Description:EnVision™ G|2 Doublestain System is a high-sensitivity peroxidase and alkaline-phosphatase-based 2nd generation visualization kit. The kit is intended for use in immunohistochemistry for the simultaneous detection of two different antigens within the same specimen, and is compatible with suitably diluted rabbit and mouse primary antibodies. The kit may be used on formalin-fixed, paraffin-em...
Company:Dako

55D Double Platform Shaker 12 x 16 from Reliable Scientific

Description:The model 55D Rocking Shaker provides the same Reliable quality as the 55S, but double the value. The 55D gives you an additional platform with a height of 3.25 in....
Company:Reliable Scientific

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Double-Affinity Purification of GST-His Tagged Proteins Using Vivapure 8-to-96 Well Cobalt-Chelate Kit

Lucia Martinez and Ario de Marco EMBL Protein Expression Core Facility, Meyerhofstr. 1, D-69117, Heidelberg, Germany Immobilized Metal ion Affinity Chromatography (IMAC) is an easy and reliable technique that allows the fast separation of His-tagged proteins from total lysates. There are several commercially available resins but all of them s...

Transient Gene Expression Following Single and Double Exponential Decay Electroporation Pulses

James R. Wong, Ph.D. and Wei-Yu Lin, Bio-Rad Laboratories A double pulse format for electroporation of mammalian tissue culture cells gave lower transient expression than a single exponential decay pulse. Moreover, separate administration of the two components of the double pulse rev...

Merge Technologies' net loss doubles to $10.1M

While the first quarter loss was well below the $27.0 million, or $0.80 per share net loss reported in the fourth quarter of...

Burke would like to double Act 255 angel tax credits

State commerce secretary Mary Burke said this week that she would like Wisconsin to double the amount of tax credits available to angel investors under the Act 255 program. In an interview, Burke said funding increases would be contingent on the state's fiscal health, but she would like to double the tax credits from the $3 million allocated in the current biennial budget. Under Act 255,...

Sonic Foundry has net loss for '05 despite nearly doubled revenue

Revenues were $8.3 million, an 89 percent increase over the previous fiscal year, with unit sales up 74 percent, owing to multiple unit sales, repeat purchases, new product offerings and increased marketing efforts....

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Double helix

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Double stranded

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Double helix

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Cancer drugs in development nearly doubled since 1995

The number of drugs being developed for the treatment of cancer has nearlydoubled during the past six years, according to a new survey of pharmaceuticalcompanies.Currently, 170 pharmaceutical and biotechnology firms various CancerInstitutes are investigating 402 compounds for the treatment of variouscancers, up from 215 in 1995. Many of the drugs are alternatives to standardradiatio...

Double impact vaccine

The virus strain which produces the measles vaccine is effective for another purpose - fighting lymphoma, a group of cancers that originate in the lymphatic system. The Scientists from Mayo clinic department of molecular medicine have found that the measles vaccine virus caused remission of lymphoma in mice injected with human cells containing the cancer.// Adele Fielding, lead...

Breast cancer risk doubles by high sex hormone levels

Postmenopausal women with relatively high serum concentrations of estrogen and testosterone have about twice the risk of developing breast cancer as women// with relatively low serum concentrations of these sex hormones. Associations between serum sex hormone levels and risk of developing breast cancer were not different in women who donated blood closer in time to diagnosis, indicating higher ho...

Down syndrome life anticipation doubles

According to a new study, people with Down syndrome live twice as long today as they did in the early 1980s'. These patients have a lower than average risk of developing many forms of cancer. The study by Quanhe Yang and colleagues published in this week's Lancet was based on data collected from death certificates between 1980 and 1995 in the US.// The researchers found that the averag...

Depression doubles mortality risk after CABG

Patients with depression are more than twice as likely to die after coronary artery bypass grafting (CABG) than patients without this mental illness, according to researchers.// Other studies examining the link between depression and CABG outcomes have been unable to reach solid conclusions either because of small sample size or short follow-up. Dr. Blumenthal and colleagues, fr...

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Storz Double Fixation Hook

Description:Flat serrated handle with polished finish. Spread between curved tips: 1.5 mm. Overall length: 5 inches. Most popular size or model....
Company:Bausch & Lomb Storz

Manson Double Ended Strabismus Hook

Description:3 mm forked angled blades. Blade spread 7 mm. Flat serrated handle with polished finish. Overall length: 4.8 inches....
Company:Bausch & Lomb Storz

Castroviejo Double Ended Synechia Spatula

Description:Double ended with 0.5 mm by 10 mm and 0.5 mm by 15 mm blades. Both ends are sharp with gently curved blades. Square serrated handle with polished finish. Most popular size or model....
Company:Bausch & Lomb Storz

Castroviejo Double Ended Cyclodialysis Spatula

Description:Double ended with 0.5 mm x 10 mm and 0.5 mm x 15 mm blades. Both blades gently curved. Square serrated handle with polished finish. Most popular size or model....
Company:Bausch & Lomb Storz

Nichamin Double Ended Nucleus Chopper-Spatula

Description:Wedge-shaped chopper designed to allow nucleus chopping in three directions, tip length 1.25 mm. Rounded tip highly polished to protect the posterior capsule. 0.5 mm spatula end is used to manipulate softer nuclei. Round knurled handle....
Company:Bausch & Lomb Storz

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Hyperthermia Plus Chemotherapy Nearly Doubles Disease-Free Survival Compared to Chemotherapy Alone for Sarcoma Cancer Patients

SALT LAKE CITY, June 04, 2007 /PRNewswire-FirstCall/ -- BSDMedical Corp. announced today that the results of a 340 patientrandomized Phase III clinical trial testing the benefit of addinghyperthermia therapy to chemotherapy were presented at the annualAmerican Society of Clinical Oncology (ASCO) conference underway inChicago, Illinois. According to the results of this clinical study,whic...

New Data Show Xenical Significantly Reduces Cardiovascular Risk and More Than Doubles Weight Loss Achieved in Overweight and Obese People

BUDAPEST, April 24 /CNW/ - The weight loss medication Xenical(orlistat 120mg) significantly reduces weight and improvescardiovascular risk factors such as blood pressure, glycaemiccontrol and lipid profile in overweight and obese people with type2 diabetes and hypertension, according to a study analysispresented at the European Congress on Obesity (ECO), Budapest,Hungary.(1) Th...

Data Show SuperGen's Multi-Targeted Tyrosine Kinase Inhibitor Suppresses Critical Double-Stranded DNA Repair Protein, Rad51

Other Presentations at AACR Highlight Progress in SuperGen'sOncology-Focused Pre-Clinical Pipeline LOS ANGELES, April 19, 2007 /PRNewswire-FirstCall/ -- SuperGenInc. today announced that MP470, its multi-targeted tyrosine kinaseinhibitor, suppresses the Rad51 protein, a critical component ofdouble- stranded DNA repair in cancer cells as part of a series ofpresentations at the 2007 America...

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Double vision

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