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Autism's social struggles due to disrupted communication networks in brain

Picking up on innuendo and social cues is a central component of engaging in conversation, but people with autism often struggle to determine another person's intentions in a social interaction. New research from Carnegie Mellon University sheds light on the neural mechanisms that are responsible ...

ViroPharma Announces Initiation Of Non-Toxigenic Clostridium Difficile Phase 1 Program

... thereby preventing disease. "NTCD is a novel live-organism biotherapeutic approach to restoring bacterial production against CDI that has been disrupted by antibiotic treatment," stated Dale N. Gerding, MD, Associate Chief of Staff for Research at the Hines VA Hospital. "Despite the effectiveness of c...

Patients Issue Summer Call to Action: 'We Need You to Donate Blood -- NOW'

...es a transfusion of red blood cells every four to five weeks, made possible by the generosity of those who donate blood. "My whole childhood was just disrupted by it... constantly going in and out of the hospital. I had no hope. The moment I first got transfused, I lifted up my hand and it was strong," she ...

Birth Control May Help Ward Off Bacterial Vaginosis

...dvantages that can be used for treating bacterial vaginosis," Wu said. Bacterial vaginosis occurs when the normal bacterial flora of the vagina is disrupted and replaced by an overproduction of other types of bacteria. Symptoms include a fishy odor and discharge, as well as itching, burning or pain. Women ...

Snoozing May Help Women Shed Baby Weight

...ysical activity and sleep patterns -- have not been well studied, researchers report. But as every bleary-eyed new mother knows, slumber is frequently disrupted or cut short in the first year after a baby's birth. "Sleep deprivation can cause changes in the levels of hormones involved in appetite regulatio...

Scientists locate disease switches

... consequences for the organism's function than previously thought. In one example, the function of Cdc28, an important growth protein in yeast, can be disrupted by the addition of an acetylation button, ultimately affecting the organism's ability to survive. ...

Blood vessel bends and branches put the brakes on statins

...ow, compared to those cells exposed to sluggish or disrupted blood flow. Dr Mason, who led the team from th...nd branches of blood vessels - where blood flow is disrupted and can be sluggish - are much more prone to fatty...and that this is lost in areas where blood flow is disrupted or non uniform, leading to build up of dangerous f...

World Financial Crisis and AIDS Backlash Threaten Lives

... Fight AIDS, TB and Malaria." Reacting to a new report from UNAIDS and the World Bank(1), which found that the global economic crisis has already disrupted AIDS treatment programmes in eight countries and is expected to impact programs in an additional 21 countries by the end of this year, activists from ...

Grab a Tool and Change Your Brain

...entation of themselves in the world -- could mean in terms of treatment of illness. But it could potentially help people with conditions that have disrupted their view of their place in space, such as amputees who receive hand transplants, said Cardinali, who studies at Claude Bernard University in Lyon, F...

Alterations in brain's white matter key to schizophrenia, UCLA study shows

...vior, focused on the brain's white matter which forms the major connections between different brain regions because it is known that white matter is disrupted in people who already have schizophrenia. "We found that healthy subjects showed a normal and expected increase in measures indexing white matte...
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Dirucotide Does Not Meet Primary Endpoint in Phase III MAESTRO-01 Trial in Secondary Progressive Multiple Sclerosis

...ntral nervous system(ii). MS is caused by damage to myelin, the protective sheath surrounding nerve fibers in the central nervous system, resulting in disrupted nerve impulses traveling to and from the brain and spinal cord(iii). Symptoms of MS may include vision problems, loss of balance, numbness, difficult...

Cephalon Submits NUVIGIL Supplemental New Drug Application for the Treatment of Excessive Sleepiness Associated with Jet Lag Disorder

...with jet lag disorder resulting from eastbound travel. Jet lag disorder is an acute condition that occurs when a person's internal body clock becomes disrupted as a result of rapid travel across several time zones. Based on U.S. Bureau of Labor Statistics findings, an estimated 70 million American travelers ...

In Rare Disorder, a Familiar Protein Disrupts Gene Function

...he long-established function of keeping chromosomes together also plays an important role in regulating genes in humans. When gene regulation is disrupted in the multisystem genetic disease Cornelia deLange syndrome (CdLS), children may suffer missing hands or fingers, mental retardation, growth failure,...

Pharmacyclics Initiates Phase 1 Clinical Trial of Novel Oral Btk Inhibitor for Refractory B-cell Non-Hodgkin's Lymphoma

...ve inhibitor to be tested in humans, and is Pharmacyclics' fourth product in clinical development. Bruton's tyrosine kinase is the gene that is disrupted in the human disease X-linked agammaglobulenemia (XLA). Patients with XLA are devoid of mature B-lymphocytes and immunoglobulins in the bloodstream, ...

Laser Burn Injuries in One Eye Can Disrupt Protective Immune Privilege in Both Eyes, Study Finds

...gainst which it mounts a defense. They found that immune privilege was disrupted in both eyes after six hours and continued to be disrupted even after 56 days. When they injected the same antigen into the eyes...

Heavy Marijuana Use May Damage Developing Brain in Teens, Young Adults

... PHILADELPHIA, Feb. 2 /PRNewswire-USNewswire/ -- Adolescents and young adults who are heavy users of marijuana are more likely than non-users to have disrupted brain development, according to a new study. Pediatric researchers found abnormalities in areas of the brain that interconnect brain regions involved ...

Long-term Follow Up Interim Data Show Nplate(TM) Increased and Sustained Platelet Counts in Adult Chronic ITP Patients

...any adult women as men. About Myelodysplastic Syndromes MDS is a disorder in which the production of blood cells by the bone marrow is disrupted and loses its ability to produce normal cells. There is no curative treatment for MDS, with the exception of bone marrow transplantation, and roughly ...

St. Jude Identifies Genomic Causes of a Certain Type of Leukemia Relapse

...t confer resistance to treatment and be responsible for relapse." According to the researchers, the relapse-related genetic changes commonly disrupted the machinery by which white blood cells called B cells mature and proliferate. Importantly, the relapse-related genetic changes only infrequently inv...

Findings on Bladder-Brain Link May Point to Better Treatments for Problems in Sleep, Attention

...A, July 29 /PRNewswire-USNewswire/ -- Bladder problems may leave a mark on the brain, by changing patterns of brain activity, possibly contributing to disrupted sleep and problems with attention. For one in six Americans who have overactive bladder, the involuntary bladder contractions that often trigger more ...

Sexual Function Affected by Stem Cell Transplant According to Long-Term Study

...or these patients, for those who were sexually active at the five- year mark, 46 percent of the men and 80 percent of the women reported problems that disrupted sexual function. According to the researchers, sexual dysfunction in transplant patients is likely caused by systemic therapies, such as total body i...
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Translocation

...rums, prevention, and ... ... apparently balanced reciprocal chromosomal translocation 46XX,t(X:5) ... normal, it seems that the translocation disrupted the iduronate sulphatase gene ... changes of ionic current indicate DNA translocation events. A transition from current decrease to current en...

Stuttering

... Stuttering , also known as stammering, is a speech disorder in which the flow of speech is disrupted by involuntary repetitions and prolongations of sounds, syllables, words or phrases, and involuntary silent pauses or blocks... Provides facts on ...

Heart block

...cause angina (chest pain) or myocardial infarction ( heart attack), heart ... Heart block occurs when the electrical signal is slowed or disrupted as it moves ... If you're born with it, it's called congenital heart block . ... Heart Rhythm Society The leading authority on arrhythmia, ...

Anterior cruciate ligament

... knee would wobble and move around ... The pain resulting from a torn anterior cruciate ligament varies widely. ... Explains the commonly disrupted ligament in knee, its symptoms, treatment, and rehabilitation. From the Sports Medicine Orthopedics, and Podiatry, Inc. Anterior cruciate l...
disrupted in Biological News

Cold Spring Harbor Laboratory scientists trace a novel way cells are disrupted in cancer

A research team at Cold Spring Harbor Laboratory (CSHL) is clarifying a previously unappreciated way that cellular processes are disrupted in cancer. Last year, scientists from the same CHSL team discovered that a "splicing factor" called SF2/ASF--a protein that changes the instructions for ho...

Carbon cycle was already disrupted millions of years ago

Dutch researcher Yvonne van Breugel analysed rocks from seabeds millions of years old. Carbon occurs naturally in two stable forms; atomic mass 12 (99 percent) and atomic mass 13 (1 percent). Episodes in the Jurassic and Cretaceous periods were characterised by a relatively strong increase in 12C. ...

New technique can fast-track better ionic liquids for biomass pre-treatments

...ted out while the lignin remained in solution, a requirement for recovering the sugars. This confirmed that the ionic liquid pre-treatment effectively disrupted the recalcitrance of the switchgrass biomass and helped liberate the fermentable sugars. "In comparison to untreated biomass, ionic liquid pretreat...

Hormone clue to root growth

...lants in which the cells in the meristem were made to express a mutant version of the growth-repressing protein GAI not degraded by gibberellin showed disrupted cell proliferation. Expressing this mutant form, gai, in only one tissue, the endodermis (the innermost layer of the root cortex of a plant), was suff...

Coral face 'a stormy future'

...mstances of most coral reefs around the world. Nevertheless its corals are disrupted by a major storm or bleaching every three or four years and the frequency ...e reef to form new colonies. Our research suggests this process is severely disrupted after one of these major events." If the disruption is sufficiently larg...

Fate in fly sensory organ precursor cells could explain human immune disorder

...as been used as a model to understand how Notch signaling is activated during asymmetric cell division. In a screen of fruit fly mutants that have disrupted peripheral nervous system development, Akhila Rajan and An-chi Tien, two graduate students in Bellen's laboratory, identified a mutant with a cluster ...

One of the Largest Wendy's(R) Franchisees, Tar Heel Capital, Reduces Fraud and Slashes Costs with DigitalPersona

... Card Industry Data Security Standard (PCI DSS) mandate. Furthermore, the need to frequently replace lost or forgotten swipe cards was time consuming, disrupted the flow of business, decreased productivity and increased IT costs. Now, by using the DigitalPersona fingerprint readers, managers can know for sure...

Vitamin D insufficiency linked to bacterial vaginosis in pregnant women

...mon vaginal infection in US women of childbearing age, and is common in pregnant women. BV occurs when the normal balance of bacteria in the vagina is disrupted and replaced by an overgrowth of certain bacteria. Because having BV puts a woman at increased risk for a variety of complications, such as preterm de...

Preclinical work shows how one gene causes severe mental retardation

...N.C., and Chapel Hill, N.C. -- Researchers at Duke University Medical Center and the University of North Carolina have discovered in mice how a single disrupted gene can cause a form of severe mental retardation known as Angelman syndrome. In a study published in the journal Nature Neuroscience , they fo...

Two-pronged model could help foil tough cystic fibrosis infections

... stuck to the maximum possible tobramycin dose of 1,000 micrograms per milliliter, mixed with a chelator. The combination had a dramatic effect: it disrupted the mass of established and highly resistant bacteria in human airway cells by 90 percent and it also prevented formation of damaging biofilms. In co...
disrupted in Biological Technology

Environmental Tectonics Corporation Announces Additional Hyperbaric Monoplace Chamber Sale to St. John Wound Center

...compression sickness. It is also used to promote and support healing in the management of conditions in which oxygen transport to the tissues has been disrupted by traumatic injury, infection, inflammation, or edema. St. John Health System operates hospitals in Tulsa, Owasso, Sapulpa and Bartlesville. A ...

Valdoxan(R) Granted Marketing Authorisation for the Treatment of Major Depressive Episodes in Europe

...ts as a MT1 and MT2 melatonergic receptors agonist and a 5-HT2C antagonist. As a result, Valdoxan resynchronises circadian rhythms that are profoundly disrupted in depressed patients.(8) "Valdoxan's mechanism of action is unlike those of the commonly-prescribed antidepressants, the SSRIs and SNRIs, as V...

Environmental Tectonics Corporation's BioMedical Division's Hyperbaric Chambers Address U.S. President Obama's Initiative to Computerize Medical Records

...compression sickness. It is also used to promote and support healing in the management of conditions in which oxygen transport to the tissues has been disrupted by traumatic injury, infection, inflammation, or edema. Gene Davis, President of the BioMedical Division, stated, "Hospitals are turning to ETC's...

Environmental Tectonics Corporation's BioMedical Division Announces Sale of Two Monoplace Hyperbaric Chambers

...mal atmospheric pressure. HBO is used to promote and support healing in the management of conditions in which oxygen transport to the tissues has been disrupted by traumatic injury, infection, inflammation, or edema. ETC prides itself on being the only manufacturer of a computerized monoplace hyperbaric...

Miniaturizing memory: Taking data storage to the molecular level

...ing of their basic element, the transistor. This process could soon reach its fundamental limit. As transistors approach nanoscales their operation is disrupted by quantum phenomena, such as electrons tunnelling through the barriers between wires. Current memory technologies fall into three separate groups...

Environmental Tectonics Corporation Announces the Placement of Two Monoplace Hyperbaric Chambers at Saint Barnabas Medical Center in New Jersey

...compression sickness. It is also used to promote and support healing in the management of conditions in which oxygen transport to the tissues has been disrupted by traumatic injury, infection, inflammation, or edema. ETC is the world's only manufacturer of a computerized monoplace hyperbaric chamber. The BAR...

Engineers aim to solve 'burning' computer problem

...xwell's Demon." Introduced by Scottish physicist James Clerk Maxwell in 1871, the concept theorizes that the energy flow from hot to cold could be disrupted if there were a way to control the transfer of energy between two units. Maxwell's Demon would allow one component to take the heat while the other wo...

Researchers develop new model for cystic fibrosis

...n CF-carriers, these animals did not show disease symptoms. The pigs were then bred naturally, and about one in four of the piglets were born with two disrupted copies of the gene. The researchers established that piglets lacking CFTR have the abnormal ion channel activity that is a hallmark of CF disease. ...

Genetic manipulation might model cystic fibrosis

...d the University of Missouri Columbia, used recombinant adeno-associated virus (rAAV) vectors to alter the CFTR gene in pig fibroblasts such that was disrupted or contained the most common CF-associated mutation (delta-F508). The nucleus of these cells was used to fertilize the eggs of female pigs, and male p...

JCI online early table of contents: March 6, 2008

...d the University of Missouri Columbia, used recombinant adeno-associated virus (rAAV) vectors to alter the CFTR gene in pig fibroblasts such that was disrupted or contained the most common CF-associated mutation (delta-F508). The nucleus of these cells was used to fertilize the eggs of female pigs, and male p...
disrupted in Biological Dictionary

Synteny

...synteny viewer" to find many on the 'net. One at random: ... Synteny refers to the occurrence of two or more genes on the same chromosome, ... A disrupted synteny refers to circumstances where a pair of genes are located on ... Synteny map. Human NCBI build 31 vs. Mouse NCBI build 30. Conserved .....

Muscularis

... mean? ... muscularis . muscularity. musculature. musculi pectinati. musculo ... Observe the location of the muscularis mucosae , which is often disrupted by Brunner's glands. ... Note the muscularis mucosa and the absence of glands in the ... Small, flask-like outpouchings of the mucosa through...

Multiple Cloning Site

...urification ... Multiple Cloning Sites . pUC57. Home. Search. Contacts. Order. Catalog. Support. catalog@fermentas.com ... ... gene which is disrupted by ligation of a DNA insert into the cloning site . ... multiple cloning site with the double BglII site flanking the insertion site...
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(Date:9/16/2014)... Pit Fire began on September 13, 2014. The fire ... is currently over 2,300 acres in size and is mostly ... Pit Fire was calm Monday night due to higher humidity. ... anchor point and beginning to construct a fireline on the ... resources are working on the fire: , 7 20-person Crews, ...
(Date:9/16/2014)... sick can take up residence in and on the ... troublesome symptom, according to new research at Washington University ... average, healthy individuals carry about five types of viruses ... BioMed Central Biology . The study is the first ... healthy people. , The research was conducted as ...
(Date:9/16/2014)... impact that spelled doom for the dinosaurs 66 million ... to a much greater extent than their deciduous peers, ... results are published in the journal PLOS Biology ... trove of thousands of fossilized leaves of angiosperms ... able to reconstruct the ecology of a diverse plant ...
Breaking Biology News(10 mins):Healthy humans make nice homes for viruses 2Healthy humans make nice homes for viruses 3Meteorite that doomed dinosaurs remade forests 2Meteorite that doomed dinosaurs remade forests 3Meteorite that doomed dinosaurs remade forests 4
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