Another reason to avoid high-fat diet -- it can disrupt our biological clock
Jerusalem, December 28, 2008 Indulgence in a high-fat diet can not only lead to overweight because of excessive calorie intake, but also can affect the balance of circadian rhythms everyone's 24-hour biological clock, Hebrew University of Jerusalem researchers have shown. The biological cloc...Some Weight-Loss Drugs Might Disrupt Brain Growth in Kids
Cannabinoid-blocking receptors thwarted rewiring needed for neural development, mouse study shows WEDNESDAY, May 7 (HealthDay News) -- A new class of weight-loss drugs that suppresses appetite by blocking cannabinoid receptors in the brain should be used with caution in children, U.S. ...Scripps Florida scientists develop a process to disrupt hepatitis C virion production
HCV is a significant human pathogen, infecting more than three percent of the worlds population. The incidence of infection in the United States has been estimated to be as high as 4 million cases. In the March issue of the journal PLoS Pathogens, Timothy Tellinghuisen, an assistant professor in t...Gleevec May Disrupt Ovarian Function
Benefits still outweigh potential infertility risks, experts say WEDNESDAY, March 5 (HealthDay News) -- Although it's a much more targeted treatment than standard chemotherapy, the effective and much-touted leukemia drug, Gleevec, isn't without side effects. In women still in thei...Farm Bill Provision Will Disrupt MaineCare Program
Over 40 million Needy Children and Adults to be Affected Nationwide, Study Expects WASHINGTON, Feb. 29 /PRNewswire-USNewswire/ -- A survey released today by Spectrum Science Communications states that a little known anti-privatization measure in the current farm b...Farm Bill Provision Will Disrupt Kentucky Medical Program
Over 40 million Needy Children and Adults to be Affected Nationwide, Study Expects WASHINGTON, Feb. 29 /PRNewswire-USNewswire/ -- A survey released today by Spectrum Science Communications states that a little known anti-privatization measure in the current farm b...Farm Bill Provision Will Disrupt Kansas Medicaid Program
Over 40 million Needy Children and Adults to be Affected Nationwide, Study Expects WASHINGTON, Feb. 29 /PRNewswire-USNewswire/ -- A survey released today by Spectrum Science Communications states that a little known anti-privatization measure in the current farm b...Farm Bill Provision Will Disrupt Iowa Medicaid and Food Stamp Programs
Over 40 million Needy Children and Adults to be Affected Nationwide, Study Expects WASHINGTON, Feb. 29 /PRNewswire-USNewswire/ -- A survey released today by Spectrum Science Communications states that a little known anti-privatization measure in the current farm b...Farm Bill Provision Will Disrupt Illinois Medicaid Program
Over 40 million Needy Children and Adults to be Affected Nationwide, Study Expects WASHINGTON, Feb. 29 /PRNewswire-USNewswire/ -- A survey released today by Spectrum Science Communications states that a little known anti-privatization measure in the current farm b...Farm Bill Provision Will Disrupt Georgia Medicaid Program
Over 40 million Needy Children and Adults to be Affected Nationwide, Study Expects WASHINGTON, Feb. 29 /PRNewswire-USNewswire/ -- A survey released today by Spectrum Science Communications states that a little known anti-privatization measure in the current farm b...Laser Burn Injuries in One Eye Can Disrupt Protective Immune Privilege in Both Eyes, Study Finds
Findings have implications for treating returning vets and others exposed to laser burns BOSTON, Feb. 26 /PRNewswire-USNewswire/ -- Scientists at Schepens Eye Research Institute have shown for the first time that a laser burn to one retina can cause both eyes to lose a special protective abil...More Gene Mutations Linked to Autism Risk
...cations and deletions is thought to interfere with gene function, which can disrupt the production of proteins necessary for normal neurological development. ...coding areas in which deletions or duplications are more likely to directly disrupt biological functions," said study leader Hakon Hakonarson, M.D., Ph.D., dir...Radius Initiates Phase 2a Clinical Trial of RAD1901 in Menopausal Hot Flashes
...ymptom during menopause, experienced by more than 75% of women during the menopause transition for a median duration of four years. These symptoms can disrupt sleep and interfere with quality of life. An estimated 6,000 U.S. women reach menopause every day (more than two million per year) with a total popula...BioMarin Announces Positive Results From Phase 2A Clinical Study of 6R-BH4 in Sickle Cell Disease
...uscle, reducing blood pressure, controlling inflammation and reducing platelet aggregation. Researchers have demonstrated that a deficiency of BH4 can disrupt NO synthesis, resulting in a loss of normal endothelial NO production. This loss of endothelial NO production, commonly referred to as endothelial dys...UT Southwestern researchers disrupt biochemical system involved in cancer, degenerative disease
DALLAS Jan. 30, 2009 Screening a chemical library of 200,000 compounds, researchers at UT Southwestern Medical Center have identified two new classes that can be used to study and possibly manipulate a cellular pathway involved in many types of cancer and degenerative diseases. "The identific...Rats on islands disrupt ecosystems from land to sea, researchers find
SANTA CRUZ, CA--Seabird colonies on islands are highly vulnerable to introduced rats, which find the ground-nesting birds to be easy prey. But the ecological impacts of rats on islands extend far beyond seabird nesting colonies, according to a new study by researchers at the University of Californ...Climate gas could disrupt food chain
Levels of a climate cooling gas will change as carbon dioxide increases, affecting food webs along the way, said Dr Michael Steinke at a Science Media Centre press briefing today. Microbes in the ocean produce the gas dimethyl sulphide, or DMS. It causes clouds to form above the sea, which refl...Currents could disrupt ocean food chain
If increased precipitation and sea surface heating from global warming disrupts the Atlantic Conveyer current ?as some scientists predict ?the effect on the ocean food chain in the Atlantic and other oceans could be severe, according to a new study just published in Nature. In a worst case scenar...Sustainable agriculture at the ESA Annual Meeting
...composing dead organic matter. Some current farming practices, however, may disrupt the soil ecosystem and decrease the effectiveness of the microbe community.... lower bacterial diversity. Kumar says that conventional tillage systems disrupt soil particles and decrease soil pore size, which can lead to decreased wat...UCSF researchers identify new drug target for Kaposi's sarcoma
...mer, but the herpes virus protease dimer has consistently eluded efforts to disrupt it at its active site, the researchers said. The UCSF team set out to fi...m of the protease, which responded well to a chemical inhibitor. "If you disrupt the protein-protein interactions, you don't need the key to a specific lock...Stress signals link pre-existing sickness with susceptibility to bacterial infection
... Mitochondrial diseases disrupt the power generating machinery within cells and increase a person's susceptibility to bacterial infection, particularly in the lungs or respiratory tr...Sticky protein helps reinforce fragile muscle membranes
...e integrity of the muscle membranes. LCMV is a member of a group of viruses that can cause hemorrhagic diseases. The study suggests that these viruses disrupt the dystroglycan basal lamina interaction, rendering the cell membrane susceptible to rupture. "Considering how essential cell membranes are for li...Systems biology recommended as a clinical approach to cancer
...A more complete picture of the system's dynamic characteristics can help contribute to the development of improved diagnostics and techniques that can disrupt the progression of the disease. They discuss three case studies related to diagnostics, therapy, and drug development in detail to demonstrate how a s...Further gene mutations linked to autism risk
...viduals in families. "We focused on changes in the exons of DNAprotein-coding areas in which deletions or duplications are more likely to directly disrupt biological functions," said study leader Hakon Hakonarson. "We identified additional autism susceptibility genes, many of which belong to the neuronal...Tech upstart VoVision could disrupt the voice-recognition market
Madison, Wis. - Paul Hager admits the technology associated with his digital product isn't perfect, but he's found proprietary ways to address its flaws and transform it for the voice-recognition market. Hager, co-owner of an early-stage Madison business called VoVison , has ambitious plans f...Bacteria pack their own demise
...rt looking for substances to start the time bomb of pathogens ticking, i.e. substances that imitate the toxin protein, block the antitoxin protein, or disrupt the interaction between the toxin and antitoxin. In time, a new class of antibiotics might come out of it though Nature mostly has a countermove up i...Researchers solve 'bloodcurdling' mystery
...e, and predictive model of how the body responds to injury. It also gives insight into how bleeding disorders, such as type 2A von Willebrand disease, disrupt this regulation system, potentially leading to new avenues for treatment and diagnosis. ...Dow AgroSciences Confirms Efficacy of Zinc Finger Nucleases for Precise Genome Modification in Maize
...hrough illustrates Dow AgroSciences commitment to lead innovation in agriculture." The addition of a herbicide tolerance gene was targeted to disrupt ZmIPK1 in corn, an especially attractive choice because ZmIPK1 encodes an enzyme that is involved in biosynthesis of phytate, a component of feed corn...Chromosome breakpoints contribute to genetic variation
...nes along chromosomes and variation within the breakpoint regions contribute to the evolution of an organism's genome, Lewin said. Breakages sometimes disrupt genes or gene families that are regulated together, for example. Deletions, insertions and inversions can cause subtle or dramatic changes in how the ...FDA Accepts IND for Arno Therapeutics' Pan-DAC / Akt Inhibitor, AR-42
... molecule that modifies the acetylation of histones and other molecules, and is a targeted inhibitor of the Pan-DAC and Akt pathways. HDAC inhibitors disrupt HDAC-PP1 complexes and cause signaling kinase dephosphorylation. In preclinical studies, AR-42 has demonstrated greater potency and a competitive pro...PlusOne Dithiothreitol from GE Healthcare, formerly Amersham Biosciences
Description:... Dithiothreitol, 1 g. High quality kits and reagents for convenient sample preparation that give consistent and reliable 2-D results.Effectively disrupt cells and tissues.Clean up samples from contaminants.Efficiently dialyze small sample volumes. Accurately quantitate protein for first-dimension isoel...