Navigation Links
disrupt in Medical News

Another reason to avoid high-fat diet -- it can disrupt our biological clock

Jerusalem, December 28, 2008 Indulgence in a high-fat diet can not only lead to overweight because of excessive calorie intake, but also can affect the balance of circadian rhythms everyone's 24-hour biological clock, Hebrew University of Jerusalem researchers have shown. The biological cloc...

Some Weight-Loss Drugs Might Disrupt Brain Growth in Kids

Cannabinoid-blocking receptors thwarted rewiring needed for neural development, mouse study shows WEDNESDAY, May 7 (HealthDay News) -- A new class of weight-loss drugs that suppresses appetite by blocking cannabinoid receptors in the brain should be used with caution in children, U.S. ...

Scripps Florida scientists develop a process to disrupt hepatitis C virion production

HCV is a significant human pathogen, infecting more than three percent of the worlds population. The incidence of infection in the United States has been estimated to be as high as 4 million cases. In the March issue of the journal PLoS Pathogens, Timothy Tellinghuisen, an assistant professor in t...

Gleevec May Disrupt Ovarian Function

Benefits still outweigh potential infertility risks, experts say WEDNESDAY, March 5 (HealthDay News) -- Although it's a much more targeted treatment than standard chemotherapy, the effective and much-touted leukemia drug, Gleevec, isn't without side effects. In women still in thei...

Farm Bill Provision Will Disrupt MaineCare Program

Over 40 million Needy Children and Adults to be Affected Nationwide, Study Expects WASHINGTON, Feb. 29 /PRNewswire-USNewswire/ -- A survey released today by Spectrum Science Communications states that a little known anti-privatization measure in the current farm b...

Farm Bill Provision Will Disrupt Kentucky Medical Program

Over 40 million Needy Children and Adults to be Affected Nationwide, Study Expects WASHINGTON, Feb. 29 /PRNewswire-USNewswire/ -- A survey released today by Spectrum Science Communications states that a little known anti-privatization measure in the current farm b...

Farm Bill Provision Will Disrupt Kansas Medicaid Program

Over 40 million Needy Children and Adults to be Affected Nationwide, Study Expects WASHINGTON, Feb. 29 /PRNewswire-USNewswire/ -- A survey released today by Spectrum Science Communications states that a little known anti-privatization measure in the current farm b...

Farm Bill Provision Will Disrupt Iowa Medicaid and Food Stamp Programs

Over 40 million Needy Children and Adults to be Affected Nationwide, Study Expects WASHINGTON, Feb. 29 /PRNewswire-USNewswire/ -- A survey released today by Spectrum Science Communications states that a little known anti-privatization measure in the current farm b...

Farm Bill Provision Will Disrupt Illinois Medicaid Program

Over 40 million Needy Children and Adults to be Affected Nationwide, Study Expects WASHINGTON, Feb. 29 /PRNewswire-USNewswire/ -- A survey released today by Spectrum Science Communications states that a little known anti-privatization measure in the current farm b...

Farm Bill Provision Will Disrupt Georgia Medicaid Program

Over 40 million Needy Children and Adults to be Affected Nationwide, Study Expects WASHINGTON, Feb. 29 /PRNewswire-USNewswire/ -- A survey released today by Spectrum Science Communications states that a little known anti-privatization measure in the current farm b...
disrupt in Medical Technology

Laser Burn Injuries in One Eye Can Disrupt Protective Immune Privilege in Both Eyes, Study Finds

Findings have implications for treating returning vets and others exposed to laser burns BOSTON, Feb. 26 /PRNewswire-USNewswire/ -- Scientists at Schepens Eye Research Institute have shown for the first time that a laser burn to one retina can cause both eyes to lose a special protective abil...

Fruitfly Model of a Neuropathic Disease Demonstrates Novel Role for Proteins in the Family of aTyr Pharma's Product Class

...lies develop neurological defects that correspond to CMT in humans. While we are still trying to understand how mutations in the tRNA synthetase gene disrupt the neurological system of a complex organism, this study showed that there are neurological functions encoded in this gene." According to Jeff W...

More Gene Mutations Linked to Autism Risk

...cations and deletions is thought to interfere with gene function, which can disrupt the production of proteins necessary for normal neurological development. ...coding areas in which deletions or duplications are more likely to directly disrupt biological functions," said study leader Hakon Hakonarson, M.D., Ph.D., dir...

King Pharmaceuticals Showcases Data From Pain Pipeline of Medicines Designed to Deter Common Methods of Non-Therapeutic Use

...ure Review The potential risk for alcohol to interact with drugs and/or disrupt a drug formulation matrix is a prevalent safety concern. For extended-release opioids, there is an added concern that ethanol (EtOH) may disrupt the formulation mechanism leading to increased bioavailability of the opioi...

Optimer Pharmaceuticals Presents Results From Fidaxomicin Phase 3 Study for the Treatment of Clostridium difficile Infection

...lammation of the colon, severe diarrhea and, in the most serious cases, death. CDI typically develops from the use of broad-spectrum antibiotics that disrupt normal gastrointestinal (gut) flora, allowing C. difficile bacteria to flourish. Current therapeutic options for CDI include metronidazole and...

First Candidate from Esperance's Targeted Anti-cancer Platform, EP-100, Establishes Preclinical Proof of Concept

...reby candidates bind specifically and exclusively to cancer cells that express the target receptors on their surfaces. The positively charged peptides disrupt the negatively charged membranes of the cancer cells, causing rapid cell death by lysis. "These data not only support the continued development o...

Radius Initiates Phase 2a Clinical Trial of RAD1901 in Menopausal Hot Flashes

...ymptom during menopause, experienced by more than 75% of women during the menopause transition for a median duration of four years. These symptoms can disrupt sleep and interfere with quality of life. An estimated 6,000 U.S. women reach menopause every day (more than two million per year) with a total popula...

Got Pain?

...ony Brook School of Medicine, "injection therapy, such as Clostridial collagenase (a substance intended to reduce the collagen buildup in the palm and disrupt the contracted cord) has now shown promising results for patients with Dupuytren's contracture." Nerve pain ( http://orthoinfo.aaos.org/topic.c...

Intra-Cellular Therapies Announces Successful Outcome of a Phase II Clinical Trial with ITI-007 in Patients with Sleep Maintenance Insomnia

...d. To date more than 75 people have been exposed to ITI-007. ABOUT SLEEP MAINTENANCE DISORDERS From insomnia to sleep apnea, sleep disorders disrupt the sleep of millions of people all over the world. In particular, about 20% to 30% of the U.S. population complains of waking up frequently during t...

BioMarin Announces Positive Results From Phase 2A Clinical Study of 6R-BH4 in Sickle Cell Disease

...uscle, reducing blood pressure, controlling inflammation and reducing platelet aggregation. Researchers have demonstrated that a deficiency of BH4 can disrupt NO synthesis, resulting in a loss of normal endothelial NO production. This loss of endothelial NO production, commonly referred to as endothelial dys...
disrupt in Medical Dictionary

Nightmares

...s, the site also ... Link Shown Between Nightmares and Suicidal Symptoms ... Nightmare disorder involves frightening or unpleasant dreams that disrupt the child's sleep on several occasions and cause distress or problems with everyday life. Learn more about what causes common nightmares , how th...

Invasive

...portant council events and dates. ... July 2009 Invasive Species of the Month- Emerald Ash Borer ... Invasive species displace native species, disrupt ecosystems, and affect ... WDNR's Proposed Invasive Species Indentification, Classification and Control Rule ... This portal is designed as a ga...

Calcium channel blockers

... Calcium channel blockers are a class of drugs and natural substances which disrupt the conduction of calcium channels. Calcium antagonists, also called calcium channel blockers , treat conditions such as high blood pre...
disrupt in Biological News

UT Southwestern researchers disrupt biochemical system involved in cancer, degenerative disease

DALLAS Jan. 30, 2009 Screening a chemical library of 200,000 compounds, researchers at UT Southwestern Medical Center have identified two new classes that can be used to study and possibly manipulate a cellular pathway involved in many types of cancer and degenerative diseases. "The identific...

Rats on islands disrupt ecosystems from land to sea, researchers find

SANTA CRUZ, CA--Seabird colonies on islands are highly vulnerable to introduced rats, which find the ground-nesting birds to be easy prey. But the ecological impacts of rats on islands extend far beyond seabird nesting colonies, according to a new study by researchers at the University of Californ...

Climate gas could disrupt food chain

Levels of a climate cooling gas will change as carbon dioxide increases, affecting food webs along the way, said Dr Michael Steinke at a Science Media Centre press briefing today. Microbes in the ocean produce the gas dimethyl sulphide, or DMS. It causes clouds to form above the sea, which refl...

Currents could disrupt ocean food chain

If increased precipitation and sea surface heating from global warming disrupts the Atlantic Conveyer current ?as some scientists predict ?the effect on the ocean food chain in the Atlantic and other oceans could be severe, according to a new study just published in Nature. In a worst case scenar...

Sustainable agriculture at the ESA Annual Meeting

...composing dead organic matter. Some current farming practices, however, may disrupt the soil ecosystem and decrease the effectiveness of the microbe community.... lower bacterial diversity. Kumar says that conventional tillage systems disrupt soil particles and decrease soil pore size, which can lead to decreased wat...

UCSF researchers identify new drug target for Kaposi's sarcoma

...mer, but the herpes virus protease dimer has consistently eluded efforts to disrupt it at its active site, the researchers said. The UCSF team set out to fi...m of the protease, which responded well to a chemical inhibitor. "If you disrupt the protein-protein interactions, you don't need the key to a specific lock...

Stress signals link pre-existing sickness with susceptibility to bacterial infection

... Mitochondrial diseases disrupt the power generating machinery within cells and increase a person's susceptibility to bacterial infection, particularly in the lungs or respiratory tr...

Sticky protein helps reinforce fragile muscle membranes

...e integrity of the muscle membranes. LCMV is a member of a group of viruses that can cause hemorrhagic diseases. The study suggests that these viruses disrupt the dystroglycan basal lamina interaction, rendering the cell membrane susceptible to rupture. "Considering how essential cell membranes are for li...

Systems biology recommended as a clinical approach to cancer

...A more complete picture of the system's dynamic characteristics can help contribute to the development of improved diagnostics and techniques that can disrupt the progression of the disease. They discuss three case studies related to diagnostics, therapy, and drug development in detail to demonstrate how a s...

Further gene mutations linked to autism risk

...viduals in families. "We focused on changes in the exons of DNAprotein-coding areas in which deletions or duplications are more likely to directly disrupt biological functions," said study leader Hakon Hakonarson. "We identified additional autism susceptibility genes, many of which belong to the neuronal...

More>>

disrupt in Biological Technology

Tech upstart VoVision could disrupt the voice-recognition market

Madison, Wis. - Paul Hager admits the technology associated with his digital product isn't perfect, but he's found proprietary ways to address its flaws and transform it for the voice-recognition market. Hager, co-owner of an early-stage Madison business called VoVison , has ambitious plans f...

Data Published in Cell Stem Cell Demonstrates Potent Anti-Cancer Activity for OncoMed Pharmaceuticals' Lead Antibody

...frequency, thereby delaying the re-growth or recurrence of tumors, anti-DLL4 therapy was shown to reduce tumor growth and tumor cell proliferation and disrupt tumor angiogenesis. Moreover, OMP-21M18 displayed additive activity in reducing tumor volume when combined with traditional chemotherapy. "Thi...

Bacteria pack their own demise

...rt looking for substances to start the time bomb of pathogens ticking, i.e. substances that imitate the toxin protein, block the antitoxin protein, or disrupt the interaction between the toxin and antitoxin. In time, a new class of antibiotics might come out of it though Nature mostly has a countermove up i...

Researchers solve 'bloodcurdling' mystery

...e, and predictive model of how the body responds to injury. It also gives insight into how bleeding disorders, such as type 2A von Willebrand disease, disrupt this regulation system, potentially leading to new avenues for treatment and diagnosis. ...

Optimer Pharmaceuticals Announces Lower Recurrence Rates for Fidaxomicin Versus Vancocin(R) in Subgroup Analyses from Its Phase 3 Study for the Treatment of CDI

...lammation of the colon, severe diarrhea and, in the most serious cases, death. CDI typically develops from the use of broad-spectrum antibiotics that disrupt normal gastrointestinal (gut) flora, allowing C. difficile bacteria to flourish. Current therapeutic options for CDI include metronidazole and...

Sangamo BioSciences Receives $100,000 Grand Challenges Explorations Grant for Innovative Global Health Research

...y, are naturally resistant to HIV infection. Sangamo has designed and engineered zinc finger DNA-binding protein nucleases (ZFN(TM)) that specifically disrupt the CCR5 gene in cells. In preclinical work published with their collaborators at the University of Pennsylvania , Sangamo researchers demonstrated ...

Dow AgroSciences Confirms Efficacy of Zinc Finger Nucleases for Precise Genome Modification in Maize

...hrough illustrates Dow AgroSciences commitment to lead innovation in agriculture." The addition of a herbicide tolerance gene was targeted to disrupt ZmIPK1 in corn, an especially attractive choice because ZmIPK1 encodes an enzyme that is involved in biosynthesis of phytate, a component of feed corn...

Chromosome breakpoints contribute to genetic variation

...nes along chromosomes and variation within the breakpoint regions contribute to the evolution of an organism's genome, Lewin said. Breakages sometimes disrupt genes or gene families that are regulated together, for example. Deletions, insertions and inversions can cause subtle or dramatic changes in how the ...

FDA Accepts IND for Arno Therapeutics' Pan-DAC / Akt Inhibitor, AR-42

... molecule that modifies the acetylation of histones and other molecules, and is a targeted inhibitor of the Pan-DAC and Akt pathways. HDAC inhibitors disrupt HDAC-PP1 complexes and cause signaling kinase dephosphorylation. In preclinical studies, AR-42 has demonstrated greater potency and a competitive pro...

Intra-Cellular Therapies Reports Positive Final Results of a Phase II Clinical Trial with ITI-007 in Patients with Sleep Maintenance Insomnia

...al diseases (e.g. Parkinson's and Alzheimer's diseases). ABOUT SLEEP MAINTENANCE DISORDERS From insomnia to sleep apnea, sleep disorders disrupt the sleep of millions of people all over the world. In particular, about 20% to 30% of the U.S. population complains of waking up frequently during t...
disrupt in Biological Products

PlusOne Dithiothreitol from GE Healthcare, formerly Amersham Biosciences

Description:... Dithiothreitol, 1 g. High quality kits and reagents for convenient sample preparation that give consistent and reliable 2-D results.Effectively disrupt cells and tissues.Clean up samples from contaminants.Efficiently dialyze small sample volumes. Accurately quantitate protein for first-dimension isoel...
Company:GE Healthcare, formerly Amersham Biosciences
disrupt in Biological Definition

Alpha helix

...e the entropic cost associated with the folding of the polypeptide chain is too high. Some amino acids (called helix breakers ) like proline will disrupt the helical structure. Ordinarily, a helix has a buildup of positive charge at the N-terminal end and negative charge at the C-terminal end which i...

Amino acid

...agine hydrophilic 132.12 5.41 2.14 8.72 P Pro Proline hydrophobic 115.13 6.30 1.95 10.64 Can disrupt protein folding structures like α helix or β sheet . Q Gln Glutamine hydrophilic 146.15 5.65 2.17 9.13 ...

Cancer

...en proliferation and cell death is tightly regulated to ensure the integrity of organs and tissues . Mutations in DNA that lead to cancer appear to disrupt these orderly processes. The uncontrolled and often rapid proliferation of cells can lead to either a benign tumor or a malignant tumor (cance...

Genetic code

...ctual frame a protein sequence is translated in is defined by a start codon , usually the first occurrence of AUG in the RNA sequence. Mutations that disrupt the reading frame (i.e. insertions or deletions of one or two nucleotide bases) severely impair the function of a protein and are thus exceedingly rar...

Gel electrophoresis

...d up into molecules with complex shapes and migrate through the gel in a complicated manner based on their tertiary structure. Therefore, agents that disrupt the hydrogen bonds , such as sodium hydroxide or formamide , are used to renature the nucleic acids and cause them to behave as long rods again. ...

Gel electrophoresis

...d up into molecules with complex shapes and migrate through the gel in a complicated manner based on their tertiary structure. Therefore, agents that disrupt the hydrogen bonds , such as sodium hydroxide or formamide , are used to renature the nucleic acids and cause them to behave as long rods again. ...

Genetic code

...ctual frame a protein sequence is translated in is defined by a start codon , usually the first occurrence of AUG in the RNA sequence. Mutations that disrupt the reading frame (i.e. insertions or deletions of one or two nucleotide bases) severely impair the function of a protein and are thus exceedingly rar...

Peptide

...e proteins) occur in nature and are responsible for a wide array of functions, many of which are not yet understood. Antimicrobial peptides generally disrupt the membranes of a target cell, causing lysis of the cell. How this occurs, and what determines the activity and selectivity of these peptides, is cur...

Peptide

...e proteins) occur in nature and are responsible for a wide array of functions, many of which are not yet understood. Antimicrobial peptides generally disrupt the membranes of a target cell, causing lysis of the cell. How this occurs, and what determines the activity and selectivity of these peptides, is cur...

Prion

...us infectious agent causing Creutzfeldt-Jakob disease resisted ultraviolet radiation (which breaks down nucleic acids), yet responded to agents that disrupt proteins. Initially, this hypothesis was highly controversial, because it seemed to contradict the " central dogma of modern biology ", which asserts ...
disrupt in Biological Dictionary

PolyA tail

...ully processed mRNA includes a 5' cap, 5' UTR, coding region, 3' UTR, and poly(A ) tail . ... Poly(A ) tail removal is thought to disrupt the circular ... In the cytoplasm, the poly(A ) tail bound by Pab1 cooperates with the cap ... supports a significant role for poly(A ) tail ...

Gene modification

... ... for the regulation of gene expression and for gene modification . ... Our ZFN gene modification technology can be used to to correct, disrupt or add a ... Gene , modification ,biological ,biology dictionary,biology terminology,biology terms,biology abbreviations ... have undergone a gen...

Denature

...lease see ... Do not heat- denature the Labeled DNA probe before this step. ... ... as boiling of clinical material to denature proteins and disrupt virions.1, 2 ... to denature proteins and release nucleic acid; this chemical process is in some ... ...
Other Tags
(Date:8/20/2014)... 2014 Medical Alert Systems, http://www.medicalalert-systems.com/ ... of some of the most popular medical alert devices ... announce that it is now offering special deals and ... are on a fixed income but would like to ... as very welcome news. , As a company spokesperson ...
(Date:8/20/2014)... iFitDress.com, the well-known wedding dress manufacturer and retailer, has ... gowns . All items in the fresh collection are ... , iFitDress.com is among the hardest working suppliers ... to help clients worldwide to keep pace with the ... professional. According to its development manager, all its products ...
(Date:8/20/2014)... 20, 2014 Today, Zane Benefits, ... publication of a new eBook, Affordable Care Act ... business owners feel uncertain about how the ACA ... their bottom line. , The new eBook outlines ... businesses navigate their upcoming health insurance decisions. , ...
(Date:8/20/2014)... HealthDay Reporter WEDNESDAY, Aug. ... dramatically during the past two decades, plummeting 57 percent and ... An estimated 4 million fewer births occurred among teenagers ... the U.S. Centers for Disease Control and Prevention. That ... report," said Bill Albert, chief program officer of The National ...
(Date:8/20/2014)... 2014 -- An imaging study of chronic users ... in specific regions of brain white matter and ... users. , Researchers used diffusuion tensor imaging ... anisotropy, to investigate the white matter integrity of ... regions of the brain, including the inferior fronto-occipital ...
Breaking Medicine News(10 mins):Health News:Medical Alert Systems Website Now Offering Special Prices on the Popular Medical Guardian Product 2Health News:Medical Alert Systems Website Now Offering Special Prices on the Popular Medical Guardian Product 3Health News:iFitDress.com Releases a New Range of Cheap Evening Gowns 2Health News:Teen Birth Rate Has Dropped Dramatically in Last Two Decades: CDC 2Health News:Teen Birth Rate Has Dropped Dramatically in Last Two Decades: CDC 3
(Date:8/20/2014)... of the Para and Mato Grosso states of Brazil. ... in order to deforest the land. Deforestation is the ... the land is thereafter converted to a nonforest use. ... ranches, or urban use. The herringbone-patterned tan lines cutting ... the middle of the image are evidence of deforestation ...
(Date:8/20/2014)... Cancer Research UK scientists have discovered that acral melanomas ... Bob Marley,s death are genetically distinct from other more ... is external) published in the journal Pigment Cell & ... palms of the hands, soles of the feet, nail-beds and ... types of melanoma, it,s not caused by UV damage from ...
(Date:8/20/2014)... Wu Feng has built upon a National Science Foundation ... Cloud" program, and synergistically complemented it with subsequent collaborative ... Force on "big computing" for mini-drones and a $1 ... Health on "big data" for the life sciences. , ... each grant, he was able to tell a much ...
Breaking Biology News(10 mins):Scientists learn more about rare skin cancer that killed Bob Marley 2The internet was delivered to the masses; parallel computing is not far behind 2The internet was delivered to the masses; parallel computing is not far behind 3The internet was delivered to the masses; parallel computing is not far behind 4
Other Contents