Protein discovery could unlock the secret to better TB treatment
UCL scientists have found a protein that could unlock the secret to quicker, more effective treatment of TB by waking TB bacteria in the body. Once the TB bacteria are active again, the disease becomes treatable using common drugs like antibiotics. Scientists believe that uncovering the molecular structure of this protein will lead the way to designing drugs which enable treatment of dormant and...Purdue proves concept of using nano-materials for drug discovery
Researchers at Purdue University have built and demonstrated a prototype for a new class of miniature devices to study synthetic cell membranes in an effort to speed the discovery of new drugs for a variety of diseases, including cancer. The researchers created a chip about one centimeter square that holds thousands of tiny vessels sitting on top of a material that contains numerous pores...Fundamental Finding Yields Insight into Stem Cells, Cancer; Opens Door to Drug Discovery
Few things about growing older are asinevitable and obvious as “going gray,?yet scientists have been unableto explain the precise cause of this usually unwelcome transformation.In a report posted today on the Web site of the journal Science,researchers from Dana-Farber Cancer Institute and Children’s HospitalBoston say they have found the cellular cause of graying hair whileinvestigating th...Discovery of key protein's shape could lead to improved bacterial pneumonia vaccine
Scientists at St. Jude Children's ResearchHospital have discovered that the shape of a protein on the surface ofpneumonia bacteria helps these germs invade the human bloodstream. Thisfinding, published Dec. 16 online by the EMBO Journal, could helpscientists develop a vaccine that is significantly more effective atprotecting children against the disease. The St. Jude researchersdetermined t...UCSD Discovery Shows How Embryonic Stem Cells Perform 'Quality Control' Inspections
A team led by Johns Hopkins scientists hasfound the first clear evidence that the process behind the human immunesystem's remarkable ability to recognize and respond to a milliondifferent proteins might have originated from a family of genes whoseonly apparent function is to jump around in genetic material. essentially cut...Imaging Mass Spectrometry for Small Molecule Localization from Protein Discovery, Inc.
Description:ions and aligns them with histological images so you can localize drugs and metabolites prior to synthesizing radiolabeled c...Small Non-coding RNA Discovery Microarray - Comprehensive Service from LC Sciences
Description:LC Sciences provides a comprehensive microarray service for systematic discovery of small regulatory/functional RNA embedded within non-coding RNAs (ncRNAs) using a novel Paraflo technology and proprietary probe design, which enables highly sensitive and specific direct detection of small RNAs (1). This comprehensive service includes custom probe design (according to submitted target RNA sequence...BD Falcon Roller Bottle, smooth surface from BD Biosciences - Discovery Labware
Description:BD Falcon 850 cm Smooth-surface TufRol Roller Bottle, tissue-culture treated polystyrene, blow-molded one-piece design, with easy on/off non-vented cap, packed in double bag. (20/ca) Packaging: 20 / double pack, 20 / case...BD Falcon Roller Bottle, smooth surface from BD Biosciences - Discovery Labware
Description:BD Falcon 850 cm Smooth-surface TufRol Roller Bottle, tissue-culture treated polystyrene, blow-molded one-piece design, with easy on/off non-vented cap. (2/sp, 20/ca) Packaging: 2 / pack, 20 / case...BD Falcon 1536-well Black/Clear Microplates from BD Biosciences - Discovery Labware
Description:BD Falcon microtest assay plate. 1536 well 12l, black BD Optilux PS. Polystyrene, nonsterile, no lid (15/sp, 60/ca)...Medical College researchers receive new grants to enhance discovery of heart-protecting anesthetics
Zeljko Bosnjak, Ph.D., professor and vi...UW discovery could lead to new TB treatments
MADISON -The family of bacteria that causes tuberculosis (TB) and leprosy are notoriously sturdy. And although the diseases they cause have been held in check for the past 50 years by antibiotics, some strains are becoming increasingly resistant to existing therapy. Now, however, a new chink has been found in the cellular armor that makes these infectious diseases difficult to treat. The...Exploiting the Life Science Data Explosion to Speed New Drug Discovery
This paper discusses key problems and opportunities created by the explosion in both the degree (volume) and complexity of life science data available today, and presents a strategic and technological approach to data integration that enables r...Bacterial discovery may help CF patients
Microbiologists from Australian and Danish have discovered a way to prevent or disturb the formation of bacterial colonies, which they believe may bring a string of benefits from preventing lung infections in cystic fibrosis sufferers to cleaner contact lenses.// The discovery, by scientists at the University of Queensland's Institute for Molecular Bioscience and the Technical University of Denma...A new discovery about Acetaminophen
According to a new enzyme which is discovered, may interpret the reasons for acetaminophen acting differently from other painkillers. //Acetaminophen (paracetamol in the UK) is known to relieve pain and fever, but not inflammation. Whereas aspirin and ibuprofen tackle inflammation too and are known as non-steroidal anti-inflammatory agents (NSAIDs). These drugs are known to block two enzymes - cy...A new discovery about Acetaminophen
According to a new enzyme which is discovered, may interpret the reasons for acetaminophen acting differently from other painkillers. //Acetaminophen (paracetamol in the UK) is known to relieve pain and fever, but not inflammation. Whereas aspirin and ibuprofen tackle inflammation too and are known as non-steroidal anti-inflammatory agents (NSAIDs). These drugs are known to block two enzymes - cy...Discovery M150 SE Microultracentrifuge
Description:Sorvall DiscoveryTMM150 SE Micro-ultra centrifuge continues to raise the standard for rapid, small volume sample processing, now with 1,048,000 x g performance and our new 4x5mL swinging bucket rotor. DiscoveryTMM150SE processes sample sizes from 0.2 ml to 8.3 ml, with a small floor footprint, brushless direct drive, very quiet operation, rotor imbalance detection, thermo-electric cooling, and a...Discovery M120 SE Microultracentrifuge
Description:The optimal combination of performance and rapid, small volume sample processing. New 4x5 mL swinging bucket rotor. DiscoveryTMM120 SE processes sample sizes from 0.2 ml to 8.3 ml, with a small floor footprint, brushless direct drive, very quiet operation, rotor imbalance detection, thermo-electric cooling, and automatic rotor locking....Major New Review Supports the Broader Potential of CeNeS COMT Inhibitor Discovery Programme
CAMBRIDGE, U.K. 2nd July 2007 - CeNeS Pharmaceuticals (AIM:CEN)("CeNeS" or "the Company") the Cambridge-based biopharmaceuticalcompany today announced that a paper published this week in CNSDrugs(1) further supports the hypothesis that acatechol-O-methyltransferase (COMT) inhibitor that acts in thebrain would be a useful agent to address profound cognitivedeficits in schizophrenia and bi...Discovery's KL-4 Surfactant Technology Demonstrates Novel Anti-Inflammatory Properties
Discovery's KL-4 Surfactant Technology Demonstrates NovelAnti-Inflammatory Properties New Surfaxin Data Presented At the 2007 Pediatric AcademicSocieties Annual Meeting WARRINGTON, Pa., May 9, 2007 (PRIME NEWSWIRE) -- DiscoveryLaboratories, Inc. (Nasdaq:DSCO) announced that new data supportingthe anti-inflammatory properties of its novel KL-4 surfactant(lucinactant) replacement tec...Major Discovery Raises Prospect of Better Patient Care By Improving Platelet Life Span
MELBOURNE, Australia, March 23, 2007 /PRNewswire/ -- Scientistsat WEHI have made a discovery with potentially profoundimplications for the care of patients, especially those undergoingcancer chemotherapy. The research team led by Drs Benjamin Kile and David Huang hasdiscovered that platelet life span is controlled by two keymolecules. The discovery raises the prospect of developing...