How Plague-Causing Bacteria Disarm Host Defense

Effector proteins are the bad guys that help bacterial pathogens do their job of infecting the host by crippling the bodys immune system. In essence, they knock down the front door of resistance and disarm the cells alarm system. Now, researchers at the University of California, San Diego ...

Scientists uncover secrets of potential bioterror virus

...VESTON, Texas Researchers at the University of Texas Medical Branch at Galveston have discovered a key tactic that the Rift Valley fever virus uses to disarm the defenses of infected cells. The mosquito-borne African virus causes fever in humans, inflicting liver damage, blindness and even death on a sm...

Anti-Tobacco Campaign Targets Twelve-and-Under Youth with Debut of "Smokerman" in New Television Ads

...ent super hero scenarios. Whether he's trying to save make-believe trains from crossing broken bridges, rescue drowning people in the kitchen sink, or disarm pretend bombs, Smokerman consistently falls short next to the other action figures because he loses his breath and misses his chance to save the day...

Emile Hirsch Visits the Democratic Republic of Congo With International Aid Agency Oxfam

...here is still much more to be done." He began his trip in the poverty-stricken Maniema Province where Oxfam is working with former child soldiers to disarm and re-integrate them back into their home communities. In some cases, the children were forcibly taken from their homes to become fighters during the...

New UCSD Program to Fight Drug-Resistant Bacteria

...pecific virulence factors that allow bacteria to cause disease,” said Nizet. “We believe the next generation of antibiotics will include products that disarm bacteria by neutralizing their virulence factors. In that way, the pathogens may be rendered harmless, without such a strong stimulus for resistance.”...

Anthrax hammers immune system

...s of Health provide some fundamental answers. They found that anthrax toxin targets front-line immune agents called dendritic cells. Once the bacteria disarm the dendritic cells, they can evade the immune system's other defenders and spread unchecked. ...

Syphilis uncovered

... the gene mapping study, said: "The genome sequence represents an encyclopedia of information on this elusive bacterium."We can now figure out ways to disarm its defences through vaccines, identify it quickly through new diagnostic tests and eliminate it with specific, targeted antibiotics." ...

disarm in Medical Technology

Rigel's R788 Shows Preclinical Activity in Type 1 Diabetes Model

...event in type 1 diabetes pathogenesis, was also observed. "Inhibition of the Syk kinase has the potential to reduce both autoantibody production and disarm its pathogenic consequences," said Raphael Clynes M.D., Ph.D., assistant professor in Medicine and Microbiology at Columbia University's College of Ph...

disarm in Medical Products

Sabre 2400

Features:...red this measurement is set. If the patient's impedance level should either increase by 20% or fall out of the preset safety range, ARM will alarm and disarm the ESU. The Assist Bar Graph provides a visual alarm set point and eliminates the possibility of pad site burns attributable to machine error....
Company:CONMED Corporation

Excaliburplus PC

Features:...red this measurement is set. If the patient's impedance level should either increase by 20% or fall out of the preset safety range, ARM will alarm and disarm the ESU. The Assist Bar Graph provides a visual alarm set point and eliminates the possibility of pad site burns attributable to machine error....
Company:CONMED Corporation

disarm in Biological News

Scientists ramp up ability of poplar plants to disarm toxic pollutants

Scientists since the early '90s have seen the potential for cleaning up contaminated sites by growing plants able to take up nasty groundwater pollutants through their roots. Then the plants break certain kinds of pollutants into harmless byproducts that the plants either incorporate into their r...

How plague-causing bacteria disarm host defense

Effector proteins are the bad guys that help bacterial pathogens do their job of infecting the host by crippling the body's immune system. In essence, they knock down the front door of resistance and disarm the cell's alarm system. Now, researchers at the University of California, San Diego (UC...

Scientists discover how plants disarm the toxic effects of excessive sunlight

A newly discovered pathway by which cells protect themselves from a toxic byproduct of photosynthesis may hold important implications for bioenergy sources, human and plant disease, and agricultural yields, a team of University of Wisconsin-Madison bacteriologists announced Monday in the Proceeding...

Poison: It's what's for dinner

...angerous," Dearing says. "Most plants make toxins to prevent from being eaten." She says little is known about how plant-eating vertebrate animals disarm plant defenses. Until the advent of genetic techniques to scan an animal's genome, or genetic blueprint, "we could only look at one, two or three enzy...

Research could lead to new non-antibiotic drugs to counter hospital infections

...onal Academies of Science . The findings could lead to new drugs that would disarm the increasingly antibiotic-resistant pathogen rather than attempting to ki... 2005, is developing a pipeline of non-antibiotic compounds that contain or disarm specific bacteria. Appreciation of the subtle mechanisms in pathogens t...

Poison: It's what's for dinner

...angerous," Dearing says. "Most plants make toxins to prevent from being eaten." She says little is known about how plant-eating vertebrate animals disarm plant defenses. Until the advent of genetic techniques to scan an animal's genome, or genetic blueprint, "we could only look at one, two or three enzy...

Brown chemist finds gray mold's killer gene

...ely shuts down toxin production, removing the special weapon the mold uses to kill and invade target plant cells. "It's a big step to being able to disarm this toxin naturally through a combination of DNA sequencing and chemistry," said Cane, the Vernon K. Krieble Professor of Chemistry and professor of ...

Ebola virus disarmed by excising a single gene

...tists to develop countermeasures. Now, however, a team of researchers from the University of Wisconsin-Madison has figured out a way to genetically disarm the virus, effectively confining it to a set of specialized cells and making the agent safe to study under conditions far less stringent than those cu...

Research holds promise for herpes vaccine

...ck, the virus can still establish an infection in animals, but the spread of the virus is stopped long before disease can occur. "In short, we can disarm the virus such that it is absolutely unable to cause disease, but is still remarkably potent as a vaccine," Halford said. In a human vaccine, the...

Researchers discover key mechanism by which lethal viruses Ebola and Marburg cause disease

...nd make them vulnerable to the body's natural defenses. "This brilliant study shows that many viruses, including HIV, use a similar mechanism to disarm their victims," said Gerald Weissmann, MD, Editor-in-Chief of The FASEB Journal. "The Columbia study has shown us new ways to fight against deadly vi...