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'Neglected infections of poverty' in US disable hundreds of thousands of Americans annually

An analysis published June 25th in the open-access journal PLoS Neglected Tropical Diseases highlights that diseases very similar to those plaguing Africa, Asia, and Latin America are also occurring frequently among the poorest people in the United States, especially women and children. These d...

New Cancer Drug Fights Tumors in Those With BRCA Mutations

...al and the department of cancer biology at the Dana-Farber Cancer Institute in Boston, and co-author of an accompanying journal editorial. When you disable PARP, you prevent the cell from repairing itself, he said, and cancer cells that are deficient in BRCA are much more sensitive to this effect. "When y...

SailPoint and Cyber-Ark Partner to Prevent Insider Threats

...McClain agreed, observing that, "The news is peppered with disgruntled or dishonest employees hijacking a company's network, planting malware bombs to disable the entire IT infrastructure or stealing sensitive customer data. Many of these security breaches can be pinpointed to a privileged account, but only ...

4-in-1

...ment in one go: Korean researchers led by Tae Gwan Park and Jinwoo Cheon have developed the basis for a four-in-one agent that can detect, target, and disable tumor cells while also making them macroscopically and microscopically visible. As they report in the journal Angewandte Chemie , their work involves...

Drug shows activity in men with advanced prostate cancer

...ths, and prevented the androgen receptor from activating additional genes later in the process, or "downstream." Other currently approved drugs cannot disable the receptor in such a way. The biopharmaceutical company Medivation, Inc., licensed RD162 and MDV3100 from UCLA in 2006 and has already completed ...

RF Technologies(R) to Release Help Alert(R) Wireless, Staff-Duress Call Solution at HIMSS09 Annual Conference and Exhibition

...data assistant (PDA). This PDA allows mobile access functions, including giving security personnel visual and audible notifications and the ability to disable an alarm at the point of incident. The device also provides communication with the reference tags and pendants for deployment, configuration and gener...

Neuro Kinetics to Release VEST(TM) 6.7 Software at Audiology Conference

... seen while performing more remote tests. The virtual pedals that appear on the guide are fully interactive and the user has the ability to enable or disable audio commands to help communicate pedal functionality. Users can now take advantage of the pedal controls during additional tests, including saccad...

Phyhealth Completes Funding Transaction with AccessKey IP, Inc.

...e and provides anti-theft protection for the PC, itself. With a standard USB connection, a PC user can employ the TeknoVault(TM) device to completely disable the PC preventing the disclosure of selected data on the computer. In addition, two TeknoVault(TM) users can exchange encrypted emails. Mr. Bru...

Warmer-Than-Average Temperatures Raise Migraine Risk

...." An estimated 28 million Americans suffer from migraine headaches, perhaps as many as 17 percent of women and 6 percent of men. The headaches can disable sufferers, forcing some to flee to quiet, darkened rooms for relief. Treatments include painkillers, biofeedback and newer drugs that relieve swell...

Sciton Unveils the JOULE Aesthetic Laser Platform for Physicians Battling the Economic Squeeze

...omic boost: contrary to industry trends, there are no hidden disposable costs, which can be $400 per tip, or charges for handpieces that automatically disable themselves after a limited number of pulses." Highest Value, Lowest-Per-Procedure Cost In addition to cost-optimization through more capabili...

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disable in Medical Technology

Aegera Initiates a Fifth Phase 1 and 2 Clinical Trial for AEG35156

...and that Canadian lymphoma patients are among the first to participate in this trial." About AEG35156 Cancer cells acquire multiple mutations that disable their normal response to apoptotic triggers. AEG35156, a second generation antisense which targets XIAP, is designed to lower the apoptotic threshold ...

Rigel's R788 Shows Preclinical Activity in Type 1 Diabetes Model

...'s and Surgeons. "In diabetes, autoantibodies against islet cells appear before the actual onset of disease providing the opportunity to intervene and disable these early events prior to immune destruction of the insulin-producing cells in the pancreas. The protection we see in these mouse models suggests th...

President Clinton Highlights MWW Group at the 2007 Clinton Global Initiative for its 'Stop Neglected Tropical Disease' Campaign

...f the world's poorest people-more than HIV/AIDS and malaria combined. In addition to killing more than 500,000 people per year, NTDs blind, disfigure, disable and are a prime contributing factor to the ongoing cycle of poverty and stigmatization that leave millions unable to work or participate in family and...

OncoGenex Technologies Announces Phase II Data of OGX-011 in Metastatic Breast Cancer at American Association for Cancer Research 2007 Annual Meeting

...on therapy. Preclinical studies have shown that inhibition of clusterin can disable the tumor cell's adaptive defences, render the tumor cells susceptible to a...cer treatments. OncoGenex' aim in targeting these particular proteins is to disable the tumor cells' adaptive defenses, render the tumor cells susceptible to a...

OncoGenex and Isis Announce OGX-011 Data to be Presented at ASCO

...on therapy. Preclinical studies have shown that inhibition of clusterin can disable the tumor cell's adaptive defences, render the tumor cells susceptible to a...cer treatments. OncoGenex' aim in targeting these particular proteins is to disable the tumor cells' adaptive defenses, render the tumor cells susceptible to a...
disable in Medical Definition

Abtissue pathology

...ue pathology was discovered and first recorded by Dan Brolynstein in conjunction with the Harvard Veterinarian Medical School. These diseases first disable the immune system before proceeding to change the chemical makeup in different parts of the nervous system , making the aforementioned brain disfunct...
disable in Biological News

Variation in HIV's ability to disable host defenses contributes to rapid evolution

One of the reasons HIV is so difficult to contain and treat is its rapid evolution. Understanding how host defenses and viral countermeasures contribute to that evolution is vital. Host cells produce two proteins that mutate HIV DNA and interfere with the virus's ability to replicate. But HIV pro...

NIH funds development of resistance-breaking insecticides to reduce malaria transmission

...the malaria mosquito, Anopheles gambiae, would pick up two inactive molecules from a bed net that would then bind to AChE within the mosquito and thus disable it. "That initial concept has not yet been realized," said Carlier. However, the team made two important advances which form the basis for the NIA...

Explorations Group Announces Letter of Intent to Acquire Specialty Lighting Company

...ly authorized drivers. Combined with optional GPS capabilities, PASS(TM) allows vehicle owners to remotely monitor, track, geo-fence, speed check and disable PASS(TM) equipped vehicles. About DRSA - Formed in 1990, Daniel R. Smith & Associates, Inc. is a leading provider of lighting solutions for ...

Explorations Group Announces Letter of Intent to Acquire Specialty Lighting Company

...ly authorized drivers. Combined with optional GPS capabilities, PASS(TM) allows vehicle owners to remotely monitor, track, geo-fence, speed check and disable PASS(TM) equipped vehicles. About DRSA - Formed in 1990, Daniel R. Smith & Associates, Inc. is a leading provider of lighting solutions for ...

Explorations Group Acquires Hawk Biometric Technologies, Inc.

...ly authorized drivers. Combined with optional GPS capabilities, PASS(TM) allows vehicle owners to remotely monitor, track, geo-fence, speed check and disable PASS(TM) equipped vehicles. David Coriaty, CEO of Hawk Biometric and the new CEO of Explorations stated "by joining with Explorations, we now ha...

Inhibiting proteins may prevent cartilage breakdown in arthritis patients

...ossible contact point for competitive inhibition. In competitive inhibition, a molecule binds with an enzyme or a protein to decrease its activity and disable its function. Many pharmaceutical drugs that are successful for treating other diseases rely on enzyme inhibitors. In this study, researchers identifi...

Shades of 1918? New study compares avian flu with a notorious killer from the past

...notable absence of these dendritic cells, suggesting they were destroyed during the infection process, which would point to H5N1's ability not only to disable the present infection but to block the body's ability to build immunity against later infection by the same type of virus. Baskin points out that ...

Biologists discover link between CGG repeats in DNA and neurological disorders

... They believe that this stalling is due to the formation of a stable, hairpin-like DNA structure formed by long CGG repeats. Abnormal structures disable cellular checkpoints "Our cells have evolved elaborate 'checkpoint' mechanisms to detect replication blocks and trigger the instant 'restart' of D...

Scripps research team sheds light on immune system suppression

...hen triggers other immune responses. But the lymphocytic choriomeningits virus, and presumably other immunosupressor viruses like measles and HIV, disable this system. This then compromises other reactions, most critically activation of the natural killers that would otherwise destroy the virus-infected ...

Researchers identify cancer-causing gene in many colon cancers

...Genes that influence such transcription factors, however, make attractive targets for drugs, since they can potentially disrupt the cancer process and disable tumor cells. CDK8 is such a gene. The new study began with a focus on a protein called beta-catenin, a transcription factor that is overactive in n...
disable in Biological Technology

Aegera Therapeutics Initiates A Randomized Phase 2 Combination Study of AEG35156 for 1st Line Treatment of Non-Small Cell Lung Cancer

...s for this innovative therapy that we hope to announce over the course of 2009." About AEG35156 Cancer cells acquire multiple mutations that disable their normal response to apoptotic triggers. AEG35156, a second generation antisense which targets XIAP, is designed to lower the apoptotic threshold ...

WallSt.net Announces Upcoming Interview With CEO of ReBuilder Medical Technologies

... the skin disease Molluscum Contagiosum which primarily affects children. This system uses its proprietary form of micronized amorphous silver ions to disable the molluscum pathogen without side effects. The company is currently performing research and development on a number of other products as well. Mor...

How to increase your online security

...oceeds to the networking package, the user is instructed by the document to disable all options in the "local area connection" properties screen. The reader is then advised to disable the "client for Microsoft networking" as well as "file and printer sharing....

Distance-Learning Remote Laboratories using LabVIEW

...in the Tools: Options menu in LabVIEW. You can use this tool to enable or disable the LabVIEW Web Server, specify the port to use for HTTP (default 80), enable or disable the log file, set the Web Server timeout (default 60 s), and even specify ...

Imaging and Analysis of DIGE Product Information Sheet, Rev B

...ls Carry out a separate spot detection on the SYPRO Ruby stained gel. Use the Automated Detection and Matching dialog box, and disable steps 3 and 4. It is not necessary for preparative gels to match perfectly to the corresponding DIGE gels in most cases the pre...
disable in Biological Products

Connect from Tecan

Description:...n optional dark cover is available to protect light-sensitive well contents from laboratory lighting Should you need to process just one plate, just disable Connect and use your reader or washer manually Connect is compact and allows front access to filter slides and plate transport of all Tecans readers...
Company:Tecan
disable in Biological Definition

Vaccine

... responses and are likely to require booster shots. Live, attenuated - these are live micro-organisms that have been cultivated under conditions to disable their virulent properties. They typically provoke durable immunological responses. Examples include yellow fever , measles , rubella , and mumps...
disable in Biological Dictionary

Replication

...shot replication acts in the ... look ahead to some planned changes and improvements for MySQL's replication . ... commands (described later) to disable the slave's replication when no connection is ... CommVault provides data replication solutions to effectively access and protect your data. .....
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