diftitox

Chemotherapy might help cancer vaccines work

...tute. Researchers used a drug called denileukin diftitox (ONTAK) for this study; the drug is routinely used...htened immune response when we used the denileukin diftitox in conjunction with the vaccine. The vaccine we us...s found that when multiple doses of the denileukin diftitox were given, immune response to the vaccine was enh...

Diptheria Toxin And Interleukin2 Help Killing Melanoma Tumour Cells

...hase II clinical trial to test the drug denileukin diftitox (also known as DAB (389) IL2 or ONTAK) in melanoma...s continuing to examine the efficacy of denileukin diftitox in patients with melanoma.' The immune system ...d kill the melanoma cells in mice.' Denileukin diftitox is a fusion protein made up of amino acid sequence...

diftitox in Medical Technology

FDA Files Application To Convert ONTAK(R) (Denileukin Diftitox) to Full Approval for Use in Cutaneous T-Cell Lymphoma (CTCL)

...er should use ONTAK (denileukin diftitox). Patients treated with denileukin diftitox must be managed in a facility equipped and staffed for cardiopulmonary resu... contraindicated for use in patients with a known sensitivity to denileukin diftitox or any of its components: diphtheria toxin, IL-2, or excipients. WARNINGS...

Ontak (denileukin diftitox) Achieves 49.1% Overall Response Rate in Phase III Trial of Cutaneous T-Cell Lymphoma (CTCL)

...-2 receptor. The safety and efficacy of denileukin diftitox in patients with CTCL whose malignant cells do not...-2 receptor. The safety and efficacy of denileukin diftitox in patients with CTCL whose malignant cells do not...leukin diftitox). Patients treated with denileukin diftitox must be managed in a facility equipped and staffed...