Watson Pharmaceuticals Resumes Shipment of INFeD(R) (Iron Dextran Injection, USP)

MORRISTOWN, N.J., July 10 /PRNewswire-FirstCall/ -- Watson Pharmaceuticals, Inc. (NYSE: WPI ), a leading specialty pharmaceutical company, announced today that it has resumed shipments to reintroduce its intravenous iron replacement therapy INFeD (iron dextran injection,USP). The product, which...

TNF-alpha antagonist stops inflammation-induced colon cancer in its tracks

...in the development of colon cancer in mice in which inflammation of the bowel was induced by administration of azoxymethane (AOM) followed by repeated dextran sulfate sodium (DSS) ingestion. Expression of TNF-alpha was increased in the colon of normal mice treated with AOM and DSS and this was followed by th...

JCI table of contents: Jan. 24, 2008

...in the development of colon cancer in mice in which inflammation of the bowel was induced by administration of azoxymethane (AOM) followed by repeated dextran sulfate sodium (DSS) ingestion. Expression of TNF-alpha was increased in the colon of normal mice treated with AOM and DSS and this was followed by th...

Small Implant To Check On Cancer

...d out about the appropriate dose of a cancer drug or its efficacy. Microscopic nanoparticles made out of iron oxide and coated with a sugar called dextran are being used in the project undertaken by a team from Massachusetts Institute of Technology (MIT). These tiny particles are coated with antibodies, ...

New Multi-Modal Contrast Agents, A Boon For Medical Imaging

...um oxide particles can be really useful.’ Watkin noted that another reason the researchers initially chose to investigate the effects of adding a dextran coating was because it makes it possible to ‘target’ the nanoparticle. ‘By that, we mean we put a ligand -- an organic substance, such as a monoc...

dextran in Medical Technology

Ardea Biosciences Presents Preclinical Anti-Inflammatory Data on its Lead MEK Inhibitor, RDEA119, at the ACG 2008 Annual Meeting

...d "RDEA119, a Potent and Highly Selective MEK1/2 Inhibitor is Beneficial in dextran Sulfate Sodium (DSS) -- induced Chronic Colitis in Mice," was presented at ...wn to significantly reduce damage to colonic tissue and disease activity in dextran sulfate sodium (DSS) -- induced chronic colitic mice. The beneficial effect...

Ardea Biosciences to Present Data on Lead MEK Inhibitor, RDEA119, at American College of Gastroenterology Annual Scientific Meeting

... 7, 2008 from 10:30 a.m. - 4:00 p.m. EDT Abstract Title: "RDEA119, a Potent and Highly Selective MEK1 / 2 Inhibitor is Beneficial in dextran Sulfate Sodium (DSS)-Induced Chronic Colitis in Mice" Poster Number: P1050 Session Title: Inflammatory Bowel Disease Location: Fl...

Ardea Biosciences Presents Preclinical Data on RDEA119 Demonstrating Favorable Anti-Inflammatory Profile for Potential Use in Ulcerative Colitis

...hown to reduce damage to colonic tissue in two different mouse models of colitis, murine trinitrobenzene sulfonic acid (TNBS) colitis model and murine dextran sulfate sodium (DSS) colitis model. The beneficial effect observed equaled or exceeded that of sulfasalazine (Azulfidine(R)), a therapy commonly used ...

Monogram Announces Posters to be Presented at the 30th San Antonio Breast Cancer Symposium

... of breast cancer markers human epidermal growth factor receptor dimer and downstream signaling proteins utilizing the VeraTag technology with dextran modified antibodies. (Presenter: J. Wallweber) About HERmark(TM) HERmark is a propriety diagnostic that accurately quantifies HER2 expression ...

Nuvelo Announces Publication of NU206 Study Results in Gastroenterology

...ncluding weight loss, diarrhea, and rectal bleeding." The study investigated the efficacy of NU206 in reducing the severity of colitis induced by dextran sulfate sodium (DSS), trinitrobenzene sulfonic acid (TNBS), and by non-steroidal anti-inflammatory drug (NSAID) treatment in interleukin (IL)-10-defic...

dextran in Medical Products

HDL Plus Control

Description:...istry analyzers: AU Series, Cobas, Dimension, Hitachi, Synchron and Vitros. HDL values are given for direct HDL methods and HDL precipitation methods: dextran Sulfate 50,000 MW. Apolipoprotein A-1 and B values are established using an IFCC standardized immunoturbidimetric method....
Company:Quantimetrix Corporation

PK® Blood Grouping Reagent Systems

Features:...time improves turnaround time Pre-qualified for optimal performance Reduce reagent costs by eliminating external potentiators such as bromelin and dextran Standardized lot to lot consistency eliminates the need to perform dilution studies Eliminates the need to perform dilution studies and modify ma...
Company:Olympus America Diagnostics

dextran in Biological News

Caffeic acid inhibits colitis in a mouse model -- is a drug-metabolizing gene crucial?

...d with inflammation responses. But only caffeic acid protected against the dextran sulfate sodium induced colitis. Its novel mechanism related to CYP4B1 is be...s in 8 week old mice fed the various dietary components and then exposed to dextran sulfate sodium in a mildly irritating dose to induce colitis. Dr. Hendrich ...

Artificial cells, simple model for complex structure

...y(ethyleneglycol) (PEG) -- a common polymer -- and dextran -- a polymerized sugar to create the cell. "Nei...id to rehydrate and form the vesicles. The PEG and dextran filled the vesicles to the same concentration as t...e lipid membrane encapsulated a mixture of PEG and dextran in water, but, the material separated to form two ...

Carnegie Mellon scientists develop nanogels that enable controlled delivery of carbohydrate drugs

...ermeable membrane. In their most recent advance, the Carnegie Mellon team incorporated the model carbohydrate drug rhodamine isothiocyanate-labeled dextran into the nanogels uniform mesh core. When the nanogels degraded, the model carbohydrate drug was released over time. The experiments were carried out ...

Genomic comparison of lactic acid bacteria published

...s that reduce ripening time and thereby save energy. Moreover, lactic acid bacteria are used for production of various commercial bioproducts such as dextran and antimicrobials. The availability of these genome sequences will foster development of additional production schemes for biofuels and other import...

Weighting cancer drugs to make them hit tumors harder

...ular weights in mouse tumors. The drug carrier they studied was dextran, essentially a chainlike string of sugar molecules. By measuring a range of dextran molecular weights in a three-dimensional model and over 30 minutes instead of a single time point, they determined the optimal weight for tumor permea...

dextran in Biological Technology

Monitoring transfection efficiency by green fluorescent protein (GFP) detection with the Agilent 2100 bioanalyzer

...r a brief period of time. There are several methods available for cell transfection such as formation of complexes of the DNA with either DEAE dextran or calcium phosphate, to facilitate entry into the cell by endocytosis, or electroporation, which uses high voltage pulses to form transient p...

Detecting Gastrin-Releasing Peptide Receptor by in situ PCR on Archived Tissue

...oducts are then detected by hybridization to digoxigeninlabeled DNA probes9 in hybridization buffer (2x SSC, 50% formamide, 7.5% dextran sulfate and 100 to 200 ng of probe). The hybridization solution is added to the slices mounted on the slides, and the slides are...

dextran in Biological Products

LIGHT DIAGNOSTICS™ CMV pp65 Dextran Leukocyte Separation Kit, included in kit #3247 from CHEMICON

Description: The Light Diagnostics Cytomegalovirus (CMV) pp65 Antigenemia Immunofluorescence Assay (IFA) is intended for the qualitative identification of lower matrix protein pp65 of CMV in isolated peripheral blood leukocytes. Kit Components: Erythrocyte Lysis Buffer - (Catalog No. 5122) One bottle conta...
Company:CHEMICON

dextran in Biological Dictionary

Vitelline membrane

...her medical and nursing definitions and dictionary terms. ... A lectin with an affinity for certain sulphated polysaccharides, such as fucoidin and dextran sulphate, has been isolated from the vitelline membrane of hens' eggs ... Definition of vitelline membrane in the Online Dictionary. Meanin...

Northern hybridization

...ybridization buffer per 10 cm2 of membrane and incubate 3 hrs. ... Northern hybridization solution. 20 ml formamide. 2 ml 20X SSPE. 8 ml 50% dextran Sulfate ... 5. Northern analysis using the probe under the same degrees of ... Northern , hybridization ,biologi cal,biology dictionary,biolog...