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Structure determined for p53 tumor suppressor protein as bound to DNA for anti-cancer activity

More than half of human cancers involve mutations in the p53 tumor-suppressor gene, suggesting the critical role played by the normal p53 protein in defending against cancer. Similarly, roughly 95 percent of cancer-causing mutations in the p53 protein occur in its DNA-binding core domain, pointing to this region of the p53 protein as being pivotal to its anti-cancer activity. Clearly, a d...

Fighting like a girl or boy determined by gene in fruit flies

Fighting like a girl or fighting like a boy is hardwired into fruit fly neurons, according to a study in the Nov. 19 Nature Neuroscience advance online publication by a research team from Harvard Medical School and the Institute of Molecular Pathology in Vienna. The results confirm that a gene known as "fruitless" is a key factor underlying sexual differences in behavior. The findings mark a mile...

Left-right wiring determined by neural communication in the embryonic worm

Most animals appear symmetrical at first glance, but we're full of internal lop-sidedness. From the hand used to pick up a pencil or throw a baseball, to where language is generated in the brain, to the orientation of our internal organs, humans are a glut of asymmetries. Worms aren't so different: The roundworm Caenorhabditis elegans has nerves on its left and right sides that perform different...
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UW-Milwaukee Chancellor Santiago determined to build on research base

Now that he's taken up residence in Wisconsin, Santiago sees no reason why UW-Milwaukee can't aspire to do the same. Santia...
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Breast cancer treatment to be determined by gene test

Women newly diagnosed with breast cancer, may opt for mastectomy over breast-conserving lumpectomy if they test positive for a breast cancer gene mutation, researchers said California on Monday. About 5% to 10% of all breast cancers are caused by an inherited genetic susceptibility. The majority of these cancers are linked to mutations or alterations in two genes, BRCA1 and BRCA2. It is...

Watch out those of you planning for a predetermined Cesarean Section

It has now become a common practice among women these days to have their baby delivered at the requested date and time by a Cesarean Section for religious regions. The trend may not be all that healthy according to a study which has found // a link between c-section delivery and higher risk of cavities in newborn and has called for special attention regarding the newborns' oral health. Th...

Age of first alcoholic drink determined by tendency to cheat

In a study conducted on factors that predispose to drinking habits, it has been established that a child’s tendency to do things like lie, steal or skip school is what encourages alcohol consumption even at a very early age of 12, 13 or 14//. The study is the first of it’s kind to focus on the issue and is a contradiction to the existing assumption that a family history of alcohol dep...

Prostate Cancer Outcomes Determined By Socioeconomic Status

More than the available treatment methods, it is the socioeconomic status of an individual that determines the prognosis of prostate cancer, according// to a new study published in the March 15, 2006 issue of CANCER, a peer-reviewed journal of the American Cancer Society. The study found that education, community poverty, and income level played an equally important role in determining t...

Child's Interest In Books Determined By Genes

A study published in Psychological Science says that children's habits are largely determined by their genes. This is especially true in determining if a child would be an avid reader. // “Children don't come into this world as clay to be molded,” said Phillip Dale, professor and chair of the Communication Science and Disorders Department in the School of Health Professions. “They do hav...

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