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Newly-discovered class of genes determines ?and restricts ?stem cell fate

Research on adult stem cells found in the skin hints at a new class of genes, according to a study from investigators at the University of Pennsylvania School of Medicine. These genes ?dubbed pangenes ?can both govern a stem cell's fate and put a hold on future differentiation until the time is right. Understanding the molecular control of these genes has implications for therapies that involve t...

Biologists determine genetic blueprint of social amoeba

An international team that includes biologists at the University of California, San Diego has determined the complete genetic blueprint of Dictyostelium discoideum, a simple social amoeba long used by researchers as a model genetic system, much like fruit flies and laboratory mice, to gain a better understanding of human diseases. The scientific details of this seven-year-long genetic seq...

International Team Determines Geographic Origin of Leprosy

Leprosy likely originated in East Africa and spread to Asia and Europe before being imported into West Africa by explorers, report scientists in this week's issue of Science. The findings enrich the historical understanding of leprosy's global migration and contradict a commonly held view that leprosy spread to West Africa directly from East Africa, say the researchers. The international t...

USC researchers determine mechanism of action of chemotherapy drug

The chemotherapy drug motexafin gadolinium (brand name: Xcytrin, manufactured by Pharmacyclics, Inc.) works to thwart cancer cells by disrupting key enzymes involved in cellular metabolism, according to a team of researchers led by Joseph Hacia, Ph.D., assistant professor of biochemistry and molecular biology at the Keck School of Medicine of the University of Southern California. The cell...

Hidden sponges determine coral reef's nutrient cycle

Marine organisms hidden in caves, such as sponges, play an extremely important role in the nutrient cycle of coral reefs. Indeed they probably play the most important role of all, says Dutch biologist Sander Scheffers. And that is valuable information for nature conservationists who want to preserve the coral reefs. In order to protect coral reefs it is important to understand how both the...

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Using Gradient PCR to determine the optimum annealing temperature.

Problems with the amplification of a specific DNA fragment using the PCR* are an everyday occurrence in the lab. For example, unspecific secondary bands may form after the PCR reaction, which hinder, or even prevent, further analyses (cycle sequencing, mutation detection, etc.) or an unequivocal assessment of the PCR r...

Before deciding how to pay for K-12 schools, let's determine what to buy

- It's not surprising that Gov. Jim Doyle and the Republican-led Legislature are still at odds over how the state's latest budget will treat public school districts across Wisconsin. Doyle thinks he saved K-12 districts from cuts without hurting taxpayers; the Republicans believe Doyle abused his veto power and put more spending on the credit ca...

UW-Milwaukee Chancellor Santiago determined to build on research base

Now that he's taken up residence in Wisconsin, Santiago sees no reason why UW-Milwaukee can't aspire to do the same. Santia...

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Breast cancer treatment to be determined by gene test

Women newly diagnosed with breast cancer, may opt for mastectomy over breast-conserving lumpectomy if they test positive for a breast cancer gene mutation, researchers said California on Monday. About 5% to 10% of all breast cancers are caused by an inherited genetic susceptibility. The majority of these cancers are linked to mutations or alterations in two genes, BRCA1 and BRCA2. It is...

How to determine allergies?

Doctors at the Mayo Clinic felt that, one should not assume sneezing and watery eyes are always due to allergy. If you start to sneeze during the spring months, you may well assume it's a pollen allergy starting up.If all the allergy tests shows negative, the only solution or diagnosis might be pollen allergy.// Doctors at the Mayo Clinic remind us there's such a condition as non-aller...

Hormone regimen and how recently used may determine cancer risk

A new study of 3,823 post-menopausal women found that continuous combined hormone therapy(estrogen combined with 25 to 31 days per month of progestin use) was associated with an increased breast cancer risk among current users of the regimen who had been taking it for five or more years. The study however did not find any association// between use of continuous combined hormone therapy and breast...

Circadian Rhythm Could Determine Lung Function

Based on findings of a recent study researchers say that the circadian rhythms, the body's biological processes that repeat in 24-hour cycles , can significantly impact lung function and help determine peak times to exercise // or receive medical treatments . During the study changes in lung function between 8:00 a.m. and 5:00 p.m were examined. Results from the five-year study, which t...

Wife May Determine Husband’s Marijuana Use

In the first year of marriage a wife may be able to control how much a husband indulge in drinking //or substance abuse like the use of marijuana. However the reverse may not always be true. Researchers said data collected showed that in the first year of marriage for 20-somethings, husbands were more likely to start or resume smoking marijuana if their wives smoked marijuana. Husbands...

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Determine HIV 1/2 - Serum & Plasma (20 Tests)