Newly discovered pathway might help in design of cancer drugs
Johns Hopkins chemists have discovered a new way to sabotage DNA's ability to reproduce, a finding that could eventually lead to the development of new anti-cancer drugs and therapies. The method could enable future doctors to target treatment more precisely, rather than directing chemotherapeutic medication or radiation to tumors through a scattershot approach, said Marc Greenberg, a chem...Medical molecules designed to respond to visible light that can penetrate tissue
If you have ever covered a flashlight with your hand and seen the red light that still comes through, then you have seen light in the therapeutic window ?that magic wavelength that is not absorbed or reflected away by tissue. Scientists believe that they can use light at that wavelength to signal manmade molecules to release drugs at disease sites in the body. Such possibilities will be d...OneWorld Health drug receives 'Orphan' designation from U.S. and European regulatory agencies
The Institute for OneWorld Health, the first nonprofit pharmaceutical company in the U.S., announced today it has received Orphan Drug Designation from the two leading regulatory agencies in the world, the Food and Drug Administration (FDA) and the European Agency for the Evaluation of Medicinal Products (EMEA), for paromomycin to treat visceral leishmaniasis (VL). VL, also known as kala a...Designing vaccines by computer
Having vaccines developed by computer may sound unnerving but the increasing role of computer modelling in the development of new vaccines could bring new products onto the market quicker, benefiting patients and saving pharmaceutical companies millions of pounds. Researchers using informatics and computer modelling can help scientists to uncover and harness the hidden patterns in the weal...Peptide Design and Custom Synthesis from Global Peptide Services, LLC.
Description:Best pricing for 100mg-1.0g scales. Phosphopeptides are our specialty....Corning Resuable Pp Vial Rack, Non-Sterile, 50 Positions, Self Locking Design from Sigma-Aldrich
Description:This CLS number is a new product number, created to easily match Cornings product number. If showing no availability yet, please order under the old Sigma-Aldrich number (Z71,523-9) or contact customer service for assistance. ID clarifier: reusable vial rack, holds 50 vials...Power1401 laboratory interface from Cambridge Electronic Design Limited
Description:High perfomance data acquisition interface. All the functionality of the micro1401 but with a faster on-board processor, increased memory and more available channels of waveform input and output. The Power1401 also inlcudes an option for programmable front-end gain. Can be expanded from the standard 16 to 48 waveform inputs and from 4 to 8 waveform outputs at 16 bit resolution. Typical applicatio...CED 1902 isolated pre-amplifier from Cambridge Electronic Design Limited
Description:Versatile, modular, computer controlled pre-amplifier suitable for a broad range of applications. Includes an isolated electrode input for recording physiological signal such as ECG, EMG, SCR and EEG, and a transducer input for use with a wide range of bridge and other transducers. Additional options include a stimulus artefact clamp to avoid saturation when using high intensity magnetic stimulat...General Notes on Primer Design in PCR*
BioSystems Laboratory, Brinkmann Instruments Inc., Westbury, New York Perhaps the most critical parameter for successful PCR is the design of Primers. All things being equal, a poorly designed primer can result in a PCR reaction that...Debate over `intelligent design' is a not-so-wise diversion from science education
- The day an archeologist finds a fossil cat or dog in Precambrian rock is the day Charles Darwin's evolution theory is disproved. But that hasn't happened. In fact, the Earth's fossil records tell a consistent scientific story through the ages: Today's living species descended -- with modification -- from common ancestors that lived in our anci...Agilent's new network chip was designed in Wisconsin
Eau Claire, Wis. - , a firm based in Eau Claire, designs application-specific inte...First Vaccine Designed for Africa Cleared for Testing in Humans
The first AIDS vaccine candidate designed specifically for Africa will enter human trials this summer. The International AIDS Vaccine Initiative (IAVI) announced on July 11 at the 13th International AIDS Conference in Durban, South Africa, that the Medicines Control Agency (MCA) of the United Kingdom has approved Phase I testing of a DNA vaccine based on HIV subtype A, the most commo...Designer Rats Reveal Possible Heart Disease Genes
Heart disease claims about 7 million lives every year, according to the WHO. Scientists have been trying to identify the precise genes that are behind this complex disease. Now they have a new research ally: the designer rat. // In a study published in the January 15 advance online publication of Nature Genetics, researchers at The Institute for Genomic Research (TIGR) and the Medical Co...'Designer' baby for British couple
Jayson and Michelle Whitaker had what is believed to be Britain's first genetically-selected baby after receiving the treatment at a Chicago genetics institute. The new baby, named Jamie, was delivered by Caesarean section on Monday after being genetically matched, while still an IVF embryo, to his four-year-old brother Charlie. Charlie has a rare form of anemia and his parents traveled t...Couples in Britain can have “designer” babis
The British government may approve the fertility law so that couples in UK can choose the sex and possibly the genes of their “designer” babies. The UK government highlighted more than 70 fertility issues on Tuesday // that are to be totally reappraised in its proposed update of the 1990 Human Fertilization and Embryology Act. The ministers of the UK governments are possibly approving the...Olk Design Sponge Implants - 5.0 x 2.5 x 80 mm
Description:Size: 5.0 x 2.5 x 80 mm. Half oval. The original Scleral Sponge II line designed by Harvey A. Lincoff, M.D. has been modified by Dr. Joseph Olk with this half oval design. The material is a closed cell sponge which is non-toxic and non-antigenic. Implants are soft with rounded edges to minimize scleral intrusion. These implants are packaged sterile and sold five implants per box....Olk Design Sponge Implants - 7.5 x 2.75 x 80 mm
Description:Size: 7.5 x 2.75 x 80 mm. Half oval. The original Scleral Sponge II line designed by Harvey A. Lincoff, M.D. has been modified by Dr. Joseph Olk with this one-half oval design. The material is a closed cell sponge which is non-toxic and non-antigenic. Implants are soft with rounded edges to minimize scleral intrusion. These implants are packaged sterile and sold five implants per box....Weil Type Swanson Design Hammertoe Implant
Description:For implantation in proximal interphalangeal joints of the lateral toes to correct deformity associated with degenerative or rheumatoid arthritis....Contour Design Eyelid Implants (Gold)
Description:Contour Design Eyelid Implants....Allos Therapeutics' PDX Granted Orphan Medicinal Product Designation by the European Commission
WESTMINSTER, Colo., April 19, 2007 /PRNewswire-FirstCall/ --Allos Therapeutics, Inc. today announced that the Commission of theEuropean Communities, with a favorable opinion of the Committee forOrphan Medicinal Products of the European Medicines Agency (EMEA),has granted orphan drug designation to the Company's novelantifolate PDX (pralatrexate) for the treatment of patients withperipher...Pixantrone Granted Fast Track Designation by FDA for Relapsed Indolent NHL Patients
Proposed Phase III Trial Has the Potential to Demonstrate an Effecton a Serious or Life Threatening Aspect of This Disease SEATTLE, May 07, 2007 /PRNewswire-FirstCall/ -- CellTherapeutics, Inc. (CTI) announced today it received fast trackdesignation from the U.S. Food and Drug Administration (FDA) forpixantrone, a novel anthracenedione, being investigated for thepotential treatment of rel...