Depression

Depression gene may weaken mood-regulating circuit

A brain scan study suggests that a suspect gene may increase susceptibility to anxiety and depression* by weakening a circuit for processing negative emotion. People with the depression-linked gene variant showed less gray matter and weaker connections in the mood-regulating circuit. How well the circuit was connected accounted for nearly 30 percent of their anxious temperament, researchers at th...

Swimming with dolphins can alleviate depression

Swimming with dolphins is an effective treatment for mild to moderate depression, say researchers in this week's BMJ. The study was carried out in Honduras and involved 30 patients diagnosed with mild or moderate depression. Hal...

In SAD patients, autumn antidepressants can prevent winter depression

For patients with seasonal affective disorder (SAD), starting treatment with an antidepressant medication during the fall can reduce the risk of developing depression throughout the fall and winter months, reports a study in the Oct. 15 issue of Biological Psychiatry, official journal of the Society of Biological Psychiatry, published by Elsevier, a world-leading scientific and medical publisher....

Depression model leaves mice with molecular scar

In addition to triggering a depression-like social withdrawal syndrome, repeated defeat by dominant animals leaves a mouse with an enduring "molecular scar" in its brain that could help to explain why depression is so difficult to cure, suggest researchers funded by the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH). In mice exposed to this animal model o...

Ever-happy mice may hold key to new treatment of depression

A new breed of permanently 'cheerful' mouse is providing hope of a new treatment for clinical depression. TREK-1 is a gene that can affect transmission of serotonin in the brain. Serotonin is known to play an important role in mood, sleep and sexuality. By breeding mice with an absence of TREK-1, researchers were able create a depression-resistant strain. The details of this research, which invol...

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Inbreeding depression

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Depression at Medicine News

Low Cholesterol Linked to Severe Depression and Violent Behavior in Men

It is not high levels of cholesterol but low levels that are making news. Recent reports are indicating that Low levels of Cholesterol maybe linked to depression and violent behavior. A new study shows that men with relatively low cholesterol levels were up to seven times more likely to report symptoms of severe depression. Edward Suarez, PhD from Duke University Medical Center in Durham, N.C....

Depression may cause delayed wound healing

Researchers in the UK say that wound healing in depressed people is four times slower than that of normal people. These and related reports find a place in the latest issue of the journal, “Psychosomatic Medicine”. Psychological factors could have direct and indirect effects on the rate of wound healing, according to the researchers. Depression and other psychological problems have been...

Diabetes and Depression often go hand-in-hand

An analysis of 25 years of data has revealed that diabetes and depression go hand in hand for many people. People with Diabetes are twice as likely as non-diabetics to suffer from depression, researchers say. The June issue of Diabetes Care carries the report of this study. Dr. Patrick Lustman of Washington University School of Medicine and the Department of Veterans Affairs Medical Center in St....

Depression and heart failure

According to a new study at the Duke University in the United States, depression increases the risk of dying from heart failure. The link between depression and coronary artery disease is well established and generally have a worse outcome. They screened 357 patients diagnosed with heart failure for depression. They found depressive symptoms in 35.3%,with 13.9% being classed as// suff...

Depression disturbs heart rate

Researchers have shed new light on how depression worsens the outlook in heart disease.Mounting evidence suggests a link between depression and heart attacks. Researchers at Washington University School of Medicine now have a new clue as to why your state of mind may affect the health of your heart. They followed a subset of participants in the Enhancing Recovery in Coronary Heart Disease trial...

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Stanford Researchers Find Brain Pathway of Depression in Rats

STANFORD, Calif.--(BUSINESS WIRE)--Jul 5, 2007 - Scientists' huntfor the cause of depression has implicated so many suspects andfound so many treatments with different mechanisms that thecondition remains an enigma. Now researchers at the StanfordUniversity School of Medicine have identified one unifyingprinciple that could explain how a range of causes and treatmentsfor depression converge...

Cipralex demonstrates superiority to duloxetine for acute treatment of depression in new study

COPENHAGEN, June 4, 2007-A new study published today in thejournal Current Medical Research and Opinion showed thatCipralex® (escitalopram) was superior to Cymbalta®(duloxetine) in the acute treatment of patients with majordepressive disorder (MDD) and was at least as efficacious inlong-term treatment. The study directly compared Cipralex® (anallosteric serotonin reuptake inh...

Newly Published Data Demonstrates Superiority of Cipralex Over Duloxetine for Acute Treatment of Depression

- Cipralex Better Tolerated and at Least as Effective inLong-Term Treatment H. Lundbeck A/S announces new study data published today in thejournal Current Medical Research and Opinion, demonstrating thatCipralex(R) (escitalopram) was superior to duloxetine in the acutetreatment of patients with major depressive disorder (MDD)...

In New Study, Duloxetine Was Equally Effective, Regardless of Switch Method, in Reducing Painful Symptoms in Ssri Non- or Partial-responders with Depression

SAN DIEGO, California, 23 May 2007 - The antidepressant duloxetinehydrochloride was equally effective in reducing painful symptoms indepressed patients who did not respond, or responded onlypartially, to treatment with a selective serotonin reuptakeinhibitor (SSRI), regardless of whether those patients wereswitched from an SSRI abruptly or gradually. This newdata was presented t...

MUSC Research Offers Hope for Those Resistant to Depression Treatment

CHARLESTON, S.C., March 23, 2007 /PRNewswire/ -- Researchers atthe Medical University of South Carolina (MUSC) have announced theresults of a two-year study, which tested the long-termantidepressant response to VNS (Vagus Nerve Stimulation)Therapy(TM) in patients with treatment-resistant depression (TRD).The study, of which Mark S. George, M.D., MUSC DistinguishedProfessor of Psychiatry,...

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Depression at Medicine Dictionary

Manic Depression

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Major depression

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Adolescent depression

Adolescent depres...