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denileukin in Medical News

Chemotherapy might help cancer vaccines work

...ancer Institute. Researchers used a drug called denileukin diftitox (ONTAK) for this study; the drug is routi... saw a heightened immune response when we used the denileukin diftitox in conjunction with the vaccine. The vacc... researchers found that when multiple doses of the denileukin diftitox were given, immune response to the vaccin...

Diptheria Toxin And Interleukin2 Help Killing Melanoma Tumour Cells

...part of a phase II clinical trial to test the drug denileukin diftitox (also known as DAB (389) IL2 or ONTAK) in... II trial is continuing to examine the efficacy of denileukin diftitox in patients with melanoma.' The immun... if the Tregs were depleted by targeting them with denileukin diftitox, then particular T cells in the immune sy...
denileukin in Medical Technology

FDA Files Application To Convert ONTAK(R) (Denileukin Diftitox) to Full Approval for Use in Cutaneous T-Cell Lymphoma (CTCL)

...ONTAK (denileukin diftitox). Patients treated with denileukin diftitox must be managed in a facility equipped an...ed for use in patients with a known sensitivity to denileukin diftitox or any of its components: diphtheria toxi...ptoms may persist or worsen after the cessation of denileukin diftitox. -- Cases of vascular (capillary) leak ...

Ontak (denileukin diftitox) Achieves 49.1% Overall Response Rate in Phase III Trial of Cutaneous T-Cell Lymphoma (CTCL)

...express the CD25 component of the IL-2 receptor. The safety and efficacy of denileukin diftitox in patients with CTCL whose malignant cells do not express the CD2...express the CD25 component of the IL-2 receptor. The safety and efficacy of denileukin diftitox in patients with CTCL whose malignant cells do not express the CD2...
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