Poison dart frog mimics gain when birds learn to stay away
Studying neotropical poison dart frogs, biologists at the University of Texas at Austin uncovered a new way that the frog species can evolve to look similar, and it hinges on the way predators learn to avoid the toxic, brightly colored amphibians. In the Mar. 8 issue of Nature, Catherine Darst and Molly Cummings show that a harmless, colorful frog living in the Amazonian rainforest gets p...Dartmouth study finds that arsenic inhibits DNA repair
Dartmouth researchers, working with scientists at the University of Arizona and at the Department of Natural Resources in Sonora, Mexico, have published a study on the impact of arsenic exposure on DNA damage. They have determined that arsenic in drinking water is associated with a decrease in the body's ability to repair its DNA. "This work supports the idea that arsenic in drinking wate...GlycoFi and Dartmouth report full humanization of yeast glycosylation pathway in Science
For the first time, scientists have engineered yeast cells capable of producing a broad repertoire of recombinant therapeutic proteins with fully human sugar structures (glycosylation). These sugar structures ensure a glycoprotein's biological activity and half-life and to date, have necessitated the expression of therapeutic glycoproteins in mammalian hosts. The accomplishment reported today has...Carotid Endarterectomy Beneficial for Stroke Prevention
Stroke may be reduced with the help of carotid endarterectomy, said a report in the recent issue of the journal Neurology. Carotid endarterectomy is the most frequently performed operation to prevent stroke//. There is scientific evidence to support its use to prevent future stroke, according to a clinical practice guideline published in the journal of the American Academy of Neurology...Dartmouth researchers zero-in on a gene that heightens muscle performance
A group of researchers, led by scientists at Dartmouth Medical School and Dartmouth College, have discovered and examined a gene that is capable of changing muscle metabolism and performance. // The researchers are optimistic that this discovery could assist in the management of muscle diseases. The researchers have found that the enzyme called AMP-activated protein kinase (or AMPK)...Vitamin Extends Life in Yeast, Dartmouth Medical School Researchers Find
Hanover, NH--Imagine taking a vitamin for longevity! Not yet, but a Dartmouth discovery that a cousin of niacin prolongs lifespan in yeast brings// the tantalizing possibility a step closer. The research, reported in the May 4 issue of Cell, shows how a new vitamin extends lifespan in yeast cells, much like calorie restriction does in animals. It could pave the way for developing supp...Dartmouth Professor Makes Case for Ethically Universal Stem Cell Lines
Human embryonic stem cells (hESC), those very young cells that are a biological blank slate, have the potential to become more specialized, contributing to the workings of a wide variety of organs and tissues. Their potential to treat diseases such as Parkinsons is slow to be realized because of the ongoing ethical debate over harvesting hESCs, a process called deriving hESC lines. Addit...Vitamin Extends Life in Yeast, Dartmouth Medical School Researchers Find
Hanover, NH--Imagine taking a vitamin for longevity! Not yet, but a Dartmouth discovery that a cousin of niacin prolongs lifespan in yeast brings the tantalizing possibility a step closer. The research, reported in the May 4 issue of Cell, shows how a new vitamin extends lifespan in yeast cells, much like calorie restriction does in animals. It could pave the way for developing sup...