Damage

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

Scientists at Joslin Diabetes Center have discovered one reason why infants with low birth weight have a high potential of developing type 2 diabetes later in life. In studies of mice, the researchers found that poor prenatal nutrition impairs the pancreas's ability to later secrete enough insulin in response to blood glucose. "The bottom line is that if you don't have delivery of enough...

Why do insects stop 'breathing'? To avoid damage from too much oxygen, say researchers

A new study investigating the respiratory system of insects may have solved a mystery that has intrigued physiologists for decades: why insects routinely stop breathing for minutes at a time. Challenging previous theories, researchers at UC Irvine and Humboldt University propose that insects such as grasshoppers, moths, butterflies, some types of fruit flies, beetles and bugs close off th...

Research Gives Hope For Liver Damage

Millions of patients suffering from liverdamage (cirrhosis) and failure may benefit from research by theUniversities of Edinburgh and Southampton which may lead to newlife-saving treatments. There is currently no cure for liver cirrhosisand a patient's only hope of survival is to receive a liver transplant.The Edinburgh scientists from the University's Centre for InflammationResearch, in co...

PET/MRI scans may help unravel mechanisms of prenatal drug damage

Scientists have demonstrated a new way to assess the potentially damaging effects of prenatal drug exposure--a technique that could also be used to monitor a fetus's response to therapeutic drugs--using sophisticated, noninvasive medical imaging tools. Scientists at the U.S. Department of Energy's Brookhaven National Laboratory, whose findings are reported in the February issue of the Society of...

Stem Cell Research Shows Potential for Replacing Tissue Damaged in Heart Attacks

A Medical College of Wisconsin research team, led by John W. Lough, Ph.D., professor of cell biology, neurobiology and anatomy has found that embryonic stem cells (ES cells) in animals can be cultivated to form new tissue, which eventually may help doctors learn how to replace tissue damaged as a result of a heart attack. The potential for ES cells to replace damaged or diseased cells in...

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DNA Damage and Repair - Quantification of Sub-Cellular Events Using Automated Confocal Imaging

Oxidative stress, radiation and other external insults have been shown to damage DNA molecules in cells derived from organisms as diverse as bacteria, yeast, drosophila, rodents and man (Friedberg et al. 2005). The presence of DNA damage may lead to cell cycle checkpoint arrest to allow time for DNA repair...

Assessing UV damage of hair

The results of UV exposure of human hair can be quantified with fluorescence spectroscopy. This is of significant interest to cosmetics and pharmaceutical companies that manufacture hair creams, coloring, shampoos, and conditioners. For customers involved...

Wisconsin court affirms damages in Innogenetics, Abbott patent case

Madison, Wis. - The The Madison-based court affirmed the damage award to , a biopharmaceutical company based in Gent, Belg...

Third Wave wins triple damages in patent case

A federal judge has tripled The lawsuit was decided in September after the judge found that Stratagene willfully infringed on two patents covering molecular diag...

Medical College getting $18.1 million to study radiation damage treatments

The institute is one of seven centers being funded by the <a href="http://ww...

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Damage at Biology Dictionary

Environmental damage

A secondary product, a polymer synthesized by a side branch of a major metabolic pathway of s ont...

DNA damage

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Damage at Medicine News

Evidence Links Protein Damage to Neurodegenerative diseases like Parkinson's and Alzheimer's

Neurodegenerative diseases - including Parkinson's, Alzheimer's, Diffuse Lewy body disease, and Multiple System Arophy - are collectively called synucleinopathies. Most commonly they become symptomatic due to a deficiency of a specific neurotransmitter - in the case of Parkinson's it is dopamine. When the neurons that produce these chemicals die or become impaired, which occurs with oxidation, th...

New drug to treat Heart Attack and damaged tissue

If a blood vessel in blocked the related tissue experiences ischemia, a state of low oxygen supply that slowly kills the tissue. They are referred as Ichemia / Reperfusion (IR) injury occurs during heart attacks. Understanding Ischemia / Reperfusion leads to the development of new drugs to save the damaged tissue and treat heart attack. During Ischemia / Reperfusion, Early growth respons...

Eating disorder in Diabetic girls lead to eyesight damage.

Diabetic girls were more likely to have an eating disorder when compared with non-diabetic girls. Some reported binge eating and used to take less than their prescribed dose of insulin in order to lose weight. Under dosing of insulin lead to early onset of diabetes related complications and are associated with increased risk of permanent eyesight damage. Intensive treatment to diabetes could be t...

Paracetamol May Cause Live Damage Warns Consumer Education and Research Centre

The Consumer Education and Research Centre (CERC) in Ahmedabad has alerted the Drug Control General of India against the excessive use of paracetamol. CERC says that the commonly use drug might cause potential liver damage and might lead on to liver failure. CERC Secretary Ashwini Kumar warns that consumers must be aware of the potential hazards of paracetamol more so because it is bein...

The flip side of AIDS cocktails – HAART regime damages live

HIV infected patients on highly active antiretroviral therapy (HAART regime) are forced to stop the treatment because of the toxic side effects of the treatment, which causes liver damage. According to a study led by Dr. Raymond T. Chung, who presented the findings at Digestive Disease Week in Atlanta last week, severe liver toxicity forced almost one in every four patients to stop the treatment...

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Pixantrone Combination Therapy for First-line Treatment of Aggressive Non-Hodgkin's Lymphoma Results in Reduction in Severe Toxicities Including Heart Damage When Compared to Doxorubicin-based Therapy

Positive interim results prompt request for meeting with FDA SEATTLE, July 11, 2007 /PRNewswire-FirstCall/ -- CellTherapeutics, Inc. (CTI) announced today that interim results ofits phase II/III trial comparing CPOP-R, in which pixantrone issubstituted for doxorubicin in standard CHOP-R first-line treatmentof patients with aggressive non-Hodgkin's lymphoma (NHL), resultedin essentially al...

AGI Dermatics Presents Comparative Data That Indicates OCTN-1 Skin Cells Have the Ability to Recognize, Transport and Utilize L-ergothioneine (EGT) As A Protector Against Oxidative Damage

Clinical Poster Presented at Society for Investigative Dermatology FREEPORT, N.Y., May 16, 2007 /PRNewswire/ -- AGI Dermaticsrecently announced new comparative clinical data that indicatesthat OCTN-1 skin cells have the ability to recognize, transport andutilize L-ergothioneine (EGT) as a protector against oxidativedamage, and importantly, that (EGT) acts as a more powerful andefficient a...

Aeolus Pharmaceuticals' AEOL 10113 May Play an Important Role Regulating the Oxidative Damage Induced by Ionizing Radiation

LAGUNA NIGUEL, Calif.--(BUSINESS WIRE)--Apr 23, 2007 - AeolusPharmaceuticals, Inc. (OTCBB:AOLS) announced the presentation ofdata by researchers at Loma Linda University Medical Center showingthat one of the Company's metalloporphyrin antioxidants, AEOL10113, may play an important role regulating the oxidative damageinduced by ionizing radiation. Radiation therapy is used alone or in comb...

Cleveland BioLabs Protectan CBLB502 Demonstrates Strong Survival Benefits as Mitigator Against Radiation-Induced Damage in Study

Chief Scientist to Present Results at 2007 American Association forCancer Research Annual Meeting CLEVELAND, April 09, 2007 /PRNewswire-FirstCall/ -- ClevelandBioLabs, Inc. , announced today the results of its study ofProtectan CBLB502's efficacy as a mitigator of bothgastrointestinal (GI) and hematopoietic (bone marrow/bloodproduction) radiation-induced damage in non-human primates. The...