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dUTPase in Biological News

Depression, aging, and proteins made by a virus may all play role in heart disease

...virus begins to multiply in cells in the body, it produces a protein called dutpase that, in turn, can stimulate macrophages to make even more IL-6. The mo...as the immune macrophages, reacted when exposed to the virus as well as the dutpase protein. In those experiments, the production of IL-6, as well as TNF-a...
dUTPase in Biological Products

Thermostable dUTPase from GenScript Corporation

Description: Thermostable dUTPase The thermostable dUTPase(pyrococcus fruriosus) maximizes the efficiency of high-fidelity PCR (using proofreading DNA polymerases). It removes contaminating dUTP present in PCR reactions and dNTP solutions. The presence of dUTPase in a proofreading DNA polymerase reaction ca...
Company:GenScript Corporation
dUTPase in other areas

Pfam: Family: dUTPase (PF00692)

Pfam is a large collection of protein families, represented by multiple sequence alignments and ... dUTPase hydrolyzes dUTP to dUMP and pyrophosphate, ...

Thermostable dUTPase

dUTPase is specific for dUTP and is critical for the fidelity of DNA replication ... dUTPase hydrolyzes dUTP to dUMP and pyrophosphate, simultaneously reducing dUTP ...

British Journal of Cancer - Abstract of article: Deoxyuridine ...

The BJC is owned by Cancer Research UK, a charity dedicated to understanding the causes, prevention and ... dUTPase catalyses the hydrolysis of dUTP to ...

PubMed Central Full Text

The dUTPase- mutants replicated with wild-type kinetics in the footpad and ... The dUTPase- strains established latent infections but displayed a greatly ...

Note: "Hidden" dUTPase Sequence in Human Immunodeficiency Virus Type 1 ...

The role of the dUTPase protein is to produce dUMP to decrease the intracellular ... dUTPase sequences are highly variable, and no position is strictly conserved in ...

dUTPase and Uracil-DNA Glycosylase Are Central Modulators of Antifolate ...

The activities of dUTPase and uracil-DNA glycosylase, key enzymes in uracil-DNA ... Cells overexpressing dUTPase were protected from cytotoxicity by their ability ...
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