Second messenger NAADP shows fast, dose-related impact on satiety cycle
One traditional approach to pharmaceutical design uses so-called "first messengers" ?hormones, other natural facilitators or synthetic products ?to initiate various cellular cascades for the desired physiological effect. To date, despite concerted efforts at all levels of research, this approach has failed to develop a truly successful obesity drug to address this major global health problem....FSU biologists describe key role of signal-transcribing gene during cell cycle
Study in Oct. 1 'Development' shows when, where Alzheimer's, some cancers and genetic ills beginT. Biologists at Florida State University have uncovered the pivotal role of a gene called "Cut" that acts as a sort of middleman in cell-to-cell communication. A DNA-binding protein, Cut interprets and transcribes the developmental signals sent through the "Notch" gene, which regulates a layer...A novel method to measure circadian cycles
Everyone knows morning people and late-night owls. The variation in individual circadian rhythms is an anecdotal as well as experimentally verified fact. But, until now, to systematically study circadian differences (and thereby hope to rout out the underlying genetic causes), scientists have had to rely on prolonged behavioural observation. To screen for and identify circadian rhythm variation...Microbe has huge role in ocean life, carbon cycle
Researchers at Oregon State University and Diversa Corporation have discovered that the smallest free-living cell known also has the smallest genome, or genetic structure, of any independent cell - and yet it dominates life in the oceans, thrives where most other cells would die, and plays a huge role in the cycling of carbon on Earth. In nature, apparently, bigger is not always better.</...Marine bacterium suspected to play role in global carbon and nitrogen cycles
Scientists successfully grow 'dwarf belonging to the sea' in laboratoryScientists are now revisiting, and perhaps revising, their thinking about how Archaea, an ancient kingdom of single-celled microorganisms, are involved in maintaining the global balance of nitrogen and carbon. Researchers have discovered the first Archaea known to oxidize ammonia for energy and metabolize carbon dioxide by su...Mastercycler ep gradient S thermal cycler from Eppendorf North America
Description:To keep pace with these technological advances, the challenges of tomorrow must b...Thermo Sequenase Dye Primer Manual Cycle Sequencing Kit from USB Corp.
Description:The Thermo Sequenase Dye Primer Manual Cycle Sequencing Kit is designed to be used with fluorescent dye-labeled primers and high-resolution fluorescence scanners. Sequencing reactions involve a termination step followed by standard slab gel electrophoresis and scanning of the gel to detect fluorescently tagged sequencing products. The kit components have been optimized for sequencing direc...Applied Biosystems 2720 Thermal Cycler from Applied Biosystems
Description:This personal-sized Thermal Cycler is the ideal instrument for budget-conscious labs that want to perform a full range of PCR applications. The A...RapidCycler 2 Instrument from Idaho Technology Inc.
Description:The RapidCycler is the first instrument engineered to match the speed of biochemical reactions and is used by thousands of research centers worldwide. It uses 1.5 mm Roche LightCycler Capillary tubes which are ideally suited for high-speed temperature cycling due to their thin walls and extremely high surface-area-to-volume ratio. By combining glass capillary tubes and air as the cycling medium...OmniSlide thermal Cycler from Thermo Scientific
Description:OmniSlide thermal Cycler for slide applications. 20 slide capacity. Humidity Chamber. Slide Rack can be transferred directly to Wash Module to avoid handling individual slides....Automated Fluorescent-Tag Cycle Sequencing
Stratagene Cloning Systems, Inc. *,# with Hot Top Assembly can be used to perform fluorescent-tag cyclesequencing using the ABI PRISM dye terminator cycle sequencingr...Effects of Thermal Cycler Well-To-Well Temperature Uniformity on PCR Results
Michelle Cayouette Jane Moores Jason Capodanno Michael Rahilly Stratagene produces consistent PCR results in every well. The RoboCycler systems uniquedesign uses thermal blo...New Temperature Cycler Features Interchangeable Blocks
Michelle Cayouette Jane Moores Jason Capodanno Michael Steege Michael Rahilly Stratagene Infinitytemperature cycler, a new temperature cycler withinterchangeable blocks for...Optimizing DNA Amplification Protocols using the Eppendorf Mastercycler
Peter Scheinert, PhD, Barbara Behrens, PhD, and Dietmar Kahle, PhD Peter Scheinert, PhD, Bernhard-Nocht-Institute for Tropical Medicine, Virology Dept., Bernhard-Nocht-Str. 74, D-20359 Hamburg former address: University of Kiel, Institute for General Microbiology, Am Botanischen Garten, D-24118 K...El Ni?o cycles linked to cholera outbreaks
About 11 months after the start of an El Ni?o event in the equatorial Pacific, hospitals thousands of miles away in Bangladesh can expect a surge of cholera cases, according to the first mathematical model to link climatic cycles with subsequent cholera outbreaks. Details of the climate-disease model are reported in the latest issue of the journal Science by ecologists at C...Regular exercise linked to extended menstrual cycles
According to a new study, moderate exercise may extend the time a woman has between her menstrual periods. The research supports one theory on why regular physical activity has been linked to a lower breast cancer risk. //Some evidence suggests that hormonal changes brought on by exercise may help lower the chances of breast cancer developing. However, the authors of the new study poin...Massage therapy regulates sleep cycle of newborns
A new study involving twenty mothers and their full-term infants, revealed that massage therapy helps newborns develop a more regular sleep cycle. Dr. Sari Goldstein from Tel Aviv University says that massage therapy by mothers in the perinatal // period helps infants coordinate their circadian systems with environmental cues. Circadian rhythm is a biological clock that helps humans an...Sleep cycles may be related to metabolism
US scientists have found out that mice with a mutation of a gene that controls the circadian clock tend to eat more and gain weight.// The circadian clock is a cellular mechanism that sets various rhythmic activities inside the organisms. It is this clock that sets the rhythm of sleep and wake patterns in all animals. In earlier studies, scientists had been able to find ou...Asthma and Panic- a vicious cycle
A 20-year prospective study published in Amercian Journal of Respiratory and Critical Care Medicine// has explored the relation between asthma and panic attack in young adults. Around 590 young adults were followed between ages 19 and 40 and information was obtained using semistructured diagnostic interviews. These interview scheduldes were conducted by trained professionals. At each inte...iCycler iQ Real-Time PCR Detection System
Description:The iCycler iQ real-time PCR detection system is a sophisticated optical system that neatly fits into place directly above the thermal cycler. It covers the widest range of excitation/emission wavelengths available, facilitating the greatest array of fluorescent PCR strategies. When used as part of the iCycler iQ system, the iCycler thermal cycler expands the advantages PCR brings to your researc...