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Cutaneous in Medical News

New NCCN Guidelines for Primary Cutaneous B-Cell Lymphoma and Updates to NCCN Guidelines for Non-Hodgkin's Lymphomas

NCCN presented new NCCN Clinical Practice Guidelines in Oncology(TM) for Primary Cutaneous B-Cell Lymphoma as well as important updates to the NCCN Guidelines for Non-Hodgkin's Lymphomas at the NCCN 14th Annual Conference. The new NCCN Guidelines were written to distinguish Primary B-Cell Lymphoma...

Dr. James F. Pingpank to Present at the Sixth International Symposium on Melanoma and Other Cutaneous Malignancies on March 13- 14, 2009 in New York City

NEW YORK, March 12 /PRNewswire-FirstCall/ -- Delcath Systems, Inc. (Nasdaq: DCTH ) , a medical technology company testing its proprietary Percutaneous Hepatic Perfusion ("PHP(TM)") System for the treatment of cancers of the liver, announced today that Dr. James F. Pingpank will present at The...

Improved diagnosis of cutaneous leishmaniasis thanks to new techniques

Cutaneous leishmaniasis (CL) is a non-lethal disease but can have grave consequences for the patient. Such consequences can be prevented with a rapid and accurate diagnosis and treatment. The treatment is based on clinical criteria. Therefore, it is essential to establish the number of parasites p...

TGen-led team is 1 of 7 selected for $1 million skin-cancer grants

...iew Committee and Director of the Johns Hopkins Melanoma Program. According to the grant description presented by Dr. Trent: "Early detection of cutaneous malignant melanoma offers the best form of cure. Characterization of the genes influencing melanoma risk is critical towards efforts aimed at disease ...

BioCryst Reports Second Quarter 2009 Financial Results And Provides Corporate Update

...l Phase 2 study of forodesine for the treatment of cutaneous T-cell lymphoma (CTCL). The target enrollment for...ine nucleoside phosphorylase (PNP) inhibitor for cutaneous T-cell lymphoma (CTCL). Utilizing crystallography ...cessful; that the pivotal trial with forodesine in cutaneous T-cell lymphoma (CTCL) may not meet its endpoint; ...

Consumer Alert: Minimally Invasive Cosmetic Procedures Should Not Be Taken Lightly

...ned by dermatologists, such as tumescent liposuction (liposuction using tumescent local anesthesia on awake patients), soft tissue (skin) fillers, and cutaneous laser surgery which includes the removal of tattoos, unwanted hair, and vascular birthmarks, and the treatment of sun-damaged skin. "Dermatolog...
Cutaneous in Medical Technology

FDA Files Application To Convert ONTAK(R) (Denileukin Diftitox) to Full Approval for Use in Cutaneous T-Cell Lymphoma (CTCL)

sBLA Submission Based on Data from Placebo-Controlled Phase III Trial; Largest Enrollment of CTCL Patients in a Randomized Study WOODCLIFF LAKE, N.J., June 26 /PRNewswire/ -- Eisai Corporation of North America announced today that the U.S. Food and Drug Administration (FDA) has accepted...

Tolerx Achieves Milestone with Completion of Phase Ib Clinical Study of TRX1 in Cutaneous Lupus Erythematosus

CAMBRIDGE, Mass., Jan. 15 /PRNewswire/ -- Tolerx, Inc., a biopharmaceutical company engaged in the discovery and development of novel therapies for the treatment of immune-mediated diseases, announced today the successful completion of a Phase Ib clinical study of TRX1, a novel humanized anti-...

BioCryst Initiates Enrollment in Pivotal Trial of Forodesine HCL in Patients with Cutaneous T-Cell Lymphoma (CTCL)

BIRMINGHAM, Ala., Oct. 12 /PRNewswire-FirstCall/ -- BioCryst Pharmaceuticals, Inc. (Nasdaq: BCRX ) today announced that it has initiated enrollment of the pivotal trial of its lead oncology drug candidate, forodesine HCL, in the treatment of patients with cutaneous T-cell lymphoma (CTCL). (L...

Allos Therapeutics Initiates Study of PDX in Patients with Cutaneous T-Cell Lymphoma

WESTMINSTER, Colo., Aug. 15 /PRNewswire-FirstCall/ -- Allos Therapeutics, Inc. (Nasdaq: ALTH ) today announced the initiation of patient enrollment in a Phase 1, open-label, multi-center study of the Company's novel antifolate PDX (pralatrexate) with vitamin B12 and folic acid supplementation...

Ontak (denileukin diftitox) Achieves 49.1% Overall Response Rate in Phase III Trial of Cutaneous T-Cell Lymphoma (CTCL)

Preliminary Results of Largest Randomized, Placebo-controlled Trial Ever Conducted in CTCL Presented at the American Society of Clinical Oncology CHICAGO, June 04, 2007 /PRNewswire/ -- Preliminary results of the largest randomized, placebo-controlled clinical trial ever conducted in patients with ...

USC Keck School of Medicine's Dr. Alan Epstein Receives Prestigious National Cancer Institute RAID Award for Breakthrough IL-2 Molecule Therapeutic

... melanoma incidence has elevated the disease to the sixth most common cancer in the United States. Approximately 60,000 Americans developed invasive cutaneous melanoma in 2007, with an estimated additional 48,000 or more cases of melanoma in situ. The current lifetime risk for developing invasive melanoma is...
Cutaneous in Medical Products

Anorectal Function Testing

Description:...norectal manometry procedures. The PNET software and Polygraf ID recorder use solid-state, water-perfused manometry catheters as well as self-adhesive cutaneous and anal canal EMG electrodes. This application is compatible with the Polygram VoiceControl utility, which allows the technician to control the PN...
Company:Medtronic Gastroenterology

Biofeedback Application

Description:...hic format. The PNET software and Polygraf ID multiparametric recorder uses solid-state or water-perfused manometry catheters as well as self-adhesive cutaneous and anal canal EMG electrodes....
Company:Medtronic Gastroenterology

SS-A (Ro)Anti-Extractable Nuclear Antigen (ENA) Antibodies Kit

Description:...ble nuclear antigens (ENA) [RNP, Sm, SS-A (Ro), or SS-B (La)] in human serum. SS-A (Ro) and SS-B (La) antibodies aid in the diagnosis of SLE, subacute cutaneous lupus erythematosus (SCLE) and Sjgrens syndrome....
Company:IMMCO Diagnostics

SS-B (La) Anti-Extractable Nuclear Antigen (ENA) Antibodies Kit

Description:...gG antibodies to extractable nuclear antigens (ENA) SS-B (La) in human serum. SS-A (Ro) and SS-B (La) antibodies aid in the diagnosis of SLE, subacute cutaneous lupus erythematosus (SCLE) and Sjgrens syndrome....
Company:IMMCO Diagnostics

Neuroprene Jumper's Knee

Description:...ned to help provide specific compression and lateral to medial influence of cutaneous nerve receptors (proprioceptors) in the skin and soft tissue structures. Ma...ile stimulating the specific neuropathway via traction/tension influence on cutaneous nerve receptors in the skin. The "double anchor" strap design reduces sympt...
Company:Innovation Sports

Neuroprene Medical Magic

Description:...ned to help provide specific compression and lateral to medial influence of cutaneous nerve receptors (proprioceptors) in the skin and soft tissue structures. Ma...ile stimulating the specific neuropathway via traction/tension influence on cutaneous nerve receptors in the skin. The "double anchor" strap design reduces sympt...
Company:Innovation Sports

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Cutaneous in Medical Definition

Artecoll

... multicenter clinical trial of 251 subjects. Plast Reconstr Surg. 2004; 114:964-976 ^ Sidwell, R.U.; Mcl Johnson, N; Francis, N. +; Bunker, C.B. cutaneous sarcoidal granulomas developing after Artecoll® facial cosmetic filler in a patients with newly diagnosed system sarcoidosis. Clinical & Experimen...

Biotextile

...up wich also include bandages, wound dressings, hospital linnen, preventive clothing etc. Antiseptic biotextiles are textiles used in fighting against cutaneous bacterial proliferation. Zeolite and triclosan are at the present time the most used molecules. This original property allows to fight the develop...

Proteopathy

...al amyloidosis Atrial natriuretic factor Pituitary prolactinoma Prolactin Hereditary lattice corneal dystrophy Keratoepithelin cutaneous lichen amyloidosis Keratins Corneal lactoferrin amyloidosis Lactoferrin Pulmonary alveolar proteinosis Surfactant protein C (SP-C) ...
Cutaneous in Medical Dictionary

Cutaneous

The skin is the outer covering of the body. In humans, it is the largest organ of the integumentary system made up of multiple layers of mesodermal tissues, and guards the underlying muscles, bones, ligaments and internal... Cutaneous leishmaniasis is the most common form of leishmaniasis...

Xanthoma

...looking at your skin. ... Case presentation of a patient with lesions on the upper eyelids and body. ... Xanthelasma palpebrum is the most common cutaneous xanthoma . ... Xanthoma is a skin condition in which fat builds up under the surface of the skin. ... Usually, your doctor can diagnose ...

Xanthelasma

...the upper eyelids and body. ... Xanthelasma palpebrum is the most common cutaneous xanthoma. ... Xanthelasma Palpebrarum: Condition information and pic...r other fat (lipid) ... Xanthelasma palpebrarum is the most common cutaneous xanthoma. Xanthelasma can be ... Xanthelasma symptoms, causes, dia...

Verruca

...art. Plantar wart. Subungual wart. Wart (close-up) Wart ( verruca ) with a cutaneous horn on the toe. Alternative Names Return to top ... Warts on the feet...mall, usually painless growths on the skin ... Wart ( verruca ) with a cutaneous horn on the toe. Reviewed last on: 10/28/2008 ... Warts, or verrucae ...

Vasculitis

... This section of the Lupus Foundation of America's website talks about vasculitis , and lupus. ... This cause of vasculitis is more common. ... cutaneous vasculitis . Authoritative facts about the skin from the New Zealand Dermatological Society. ... can target the blood vessels resulting in vascu...

Tinea versicolor

...gh it is an infection, tinea versicolor is not contagious, as the yeast ... Overview: Tinea versicolor is a common, benign, superficial cutaneous fungal ... In hyperpigmented macules in tinea versicolor , the organism induces an ... tinea versicolor n A fungal infection of the ski...
Cutaneous in Biological News

Source of molecular triggers in cutaneous T cell lymphoma identified

In a study published in the journal Blood, Yale scientists identify the molecular triggers that stimulate Cutaneous T Cell Lymphoma (CTCL) cells to clonally expand into large populations of malignant lymphocytes. CTCL is the most common adult malignancy of T lymphocytes, the white blood cells of...

NYU Langone Medical Center awarded NIH grants totaling $1,560,000

...of Internal Medicine, chair of the Department of Medicine, and professor of microbiology, will receive support for his study titled "Evaluation of the cutaneous Microbiome in Psoriasis." Psoriasis, affecting more than 7.5 million people in the United States, is a chronic disease involving the immune system th...

Blue light destroys antibiotic-resistant staph infection

...853 colonies. The effectiveness of blue light in vitro suggests that it should also be effective in human cases of MRSA infection, and particularly in cutaneous and subcutaneous infections. "It is inspiring that an inexpensive naturally visible wavelength of light can eradicate two common strains of MRSA. ...

Closing the gap: Journal launch brings together wound-healing knowledge

...sion in skin correlates with myofibroblast induction, and that CTGF-expressing pericytes are significant contributors to myofibroblast activity during cutaneous tissue repair. Commenting on the paper, the Editor in Chief of the new journal, Massimo Pinzani, said, "This is a good example of the type of high qua...

Researchers find cancer-inhibiting compound under the sea

...an 30 labs exist worldwide and research dollars have only become available in the past 15 years. HDACs are already targeted by a drug approved for cutaneous T-cell lymphoma manufactured by the global pharmaceutical company Merck & Co. Inc. However, UF's compound does not inhibit all HDACs equally, meaning ...

As rates rise, researchers find better way to identify melanoma

... been rising among older adults. The pilot study investigated samples of 56 biopsied lesions from 48 adults. The lesions fell into the category of cutaneous melanocytic neoplasms, a diverse group that includes benign moles; Spitz nevi, a type of mole seen in younger people that can be easily mistaken for m...
Cutaneous in Biological Technology

Yaupon Therapeutics Completes Patient Enrollment for Pivotal Phase 2 Study of Clearazide for Treatment of Cutaneous T-cell Lymphoma

Largest clinical study ever involving patients with cutaneous T-cell lymphoma on schedule for completion in June 2010 RADNOR, Pa., June 29 /PRNewswire/ -- Yaupon Therapeutics, a privately held specialty pharmaceutical company, has announced it has completed enrollment for a pivotal Phase 2 c...

BioCryst Pharmaceuticals to Announce Second Quarter 2009 Financial Results on July 30, 2009

...candidates in pivotal clinical trials; peramivir, an anti-viral for influenza, and forodesine, a purine nucleoside phosphorylase (PNP) inhibitor for cutaneous T-cell lymphoma (CTCL). Utilizing crystallography and structure-based drug design, BioCryst continues to expand its portfolio of next-generation thera...

It's Not Just the Sun: deCODE Discovers Sequence Variants Affecting Susceptibility to Skin Cancer

...ided conclusive evidence that a previously identified SNP in the TERT-CLPTM1L region of chromosome 5 confers susceptibility to BCC but protects agains cutaneous melanoma. A previously known SNP in the SLC45A2 gene on chromosome 5 was confirmed to confer risk of squamous cell carcinoma as well as BCC. The study...

Delcath Systems Granted Third Orphan Drug Designation

...This FDA decision follows two previously granted Delcath orphan drug designations for the drug melphalan for the treatment of patients with metastatic cutaneous melanoma and metastatic ocular melanoma. High dose melphalan, for the treatment of neuroendocrine tumors, is an indication that we have aggressively ...

NeurogesX Receives European Commission Approval for Qutenza(TM)

...mmission has formally granted marketing authorization of Qutenza(TM) 179 mg cutaneous patch (formerly NGX-4010) for the treatment of peripheral neuropathic pain ... for Medicinal Products for Human Use (CHMP) on March 19, 2009. Qutenza, a cutaneous (dermal) patch, is designed to locally deliver a high-concentration (8%) of...

Eric D. Whitman, MD to Present on the Delcath PHP System(TM) at the 7th World Congress on Melanoma

...itled Percutaneous Isolated Hepatic Perfusion for cutaneous and Uveal Metastatic Melanoma , will discuss his e...lan to the liver to treat patients with metastatic cutaneous and ocular melanoma who have unresectable tumors i...as a Joint Meeting covering the entire spectrum of cutaneous malignancies. Clinicians and researchers will foc...
Cutaneous in Biological Definition

Thermoregulation

...or is undoubtedly the skin, which regulates heat loss by its vasomotor mechanism, and also by the nervous mechanism of perspiration. Dilatation of the cutaneous vascular areas leads to a larger flow of blood through the skin, and so tends to cool the body, and vice versa. Also the special nerves of perspiratio...
Cutaneous in Biological Dictionary

Mosaicism

...osaicism may be detected through chromosome evaluation. ... Patients with mosaicism may require less intense treatment than those with the ... cutaneous mosaicism . Authoritative facts about the skin from the New Zealand Dermatological Society. ... Mosaicism describes an individual composed of two o...

Cell growth

...1990-September ... Original Article from The New England Journal of Medicine -- Altered Metabolism of Mast- Cell Growth Factor (c-kit Ligand) in cutaneous Mastocytosis The outermost circle represents the various cell types in C. elegans in which ... genes that promote cancer cell growth in the...

Aponeurosis

...poneurosis .—Attached to the posterior border of the hard palate is a ... Laterally it is continuous with the pharyngeal aponeurosis . ... ... cutaneous branches pierce the plantar aponeurosis between the Abductor hallucis ... the divisions of the plantar aponeurosis , and each splits into two prope...
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(Date:4/22/2014)... (SALT LAKE CITY)A computational tool developed at the University ... with unknown gene mutations in three separate cases, U ... new study in The American Journal of Human ... Re-ranking tool), identifies undiagnosed illnesses and unknown gene mutations ... proteins that code for genes are made, in individual ...
(Date:4/22/2014)... nanodot technology, Berkeley Lab researchers have demonstrated the ... used to study the membranes of living cells. ... structures can reveal information critical to whether a ... cancerous, that can,t be obtained through conventional microscopy. ... provide a physical means to both probe and ...
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(Date:4/22/2014)... may throw tantrums like toddlers, but their total ... say, a gerbil or fox squirrel, according to ... and birds ranging from orangutans to zebra finches. ... Yale and more than two-dozen other research institutions ... evolution of self-control, defined in the study as ...
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(Date:4/22/2014)... Winsor Lowe, interim director of the University of Montana,s ... in the Proceedings of the National Academy of Sciences ... network. , ... the U.S. Geological Survey, the University of Washington, the Cary ... U.S. Forest Service Northern Research Station examined 664 water samples ...
(Date:4/22/2014)... Scientists at the University of Massachusetts Amherst and the ... week report that they have discovered a new genus ... the Negro River in the Amazonia State of Brazil. ... Adlia Nogueira and Jos Antnio Alves-Gomes of INPA, describe ... the journal Proceedings of the Natural Sciences of ...
(Date:4/22/2014)... Mass. Analyzing thousands of breeding bird surveys sent ... and Canada over 35 years, wildlife researchers report that ... either northward or toward higher elevation in response to ... This means that most previous studies of potential climate ... factor or the other have likely underestimated the effects ...
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