Critical

Wisconsin scientists grow critical nerve cells

After years of trial and error, scientists have coaxed human embryonic stem cells to become spinal motor neurons, critical nervous system pathways that relay messages from the brain to the rest of the body. The new findings, reported online today (Jan. 30, 2005) in the journal Nature Biotechnology by scientists from the University of Wisconsin-Madison, are important because they provide c...

Plant hemoglobins: Oxygen handlers critical for nitrogen fixation

Hemoglobins, key components of our blood, are ancient proteins with well-known roles in oxygen transport and respiration in animals. Hemoglobins are also present in plants and bacteria, but until now the physiological role of plant hemoglobins has been unclear. A group of researchers reveal this week that one such mysterious plant hemoglobin serves to assist in the fixation of nitrogen in the roo...

Critical role in programmed cell death identified

Dartmouth Medical School geneticists have found links in the cell death machinery of worms and mammals, opening new avenues for studying and targeting a process vital to development and implicated in cancer and autoimmune diseases. The work, reported in the February 17 issue of Nature, demonstrates the role of mitochondria, the cellular power plant, in prompting worm cells to self destruc...

White blood cell waste disposal system plays critical regulatory role

A new research study identifies a critical inhibitory step that is a key component of the feedback circuit regulating the balance between neutrophil production and destruction. The research, published in the March issue of Immunity, suggests that the process for disposal of dying neutrophils is actively linked to neutrophil production. A clear understanding of the processes that control neutrophi...

White Blood Cell 'Waste Disposal' System Plays Critical Regulatory Role

A new research study identifies a critical inhibitory step that is a key component of the feedback circuit regulating the balance between neutrophil production and destruction. The research, published in the March issue of Immunity, suggests that the process for disposal of dying neutrophils is actively linked to neutrophil production. A clear understanding of the processes that control neutrophi...

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Critical at Biology Products

Supercritical fluid chromatography and extraction systems (SFC/SFE) from JASCO

Description:JASCO offers a dedicated system for SFC and SFE applications based upon the modular LC-1500 series of HPLC instrumentation. JASCO has recently added the following modules to enhance the capability of the system: - The PU-1580-CO2 delivery pump for supercritical fluid chromatography and extraction procedures using carbon dioxide as the mobile phase. - The BP-1580-81 automatic back pressure...
Company:JASCO

Critical at Biology Technology

Critical factors for successful microarray and real-time PCR analyses

QIAGEN GmbH, Hilden, Germany Gene expression profiling at the RNA level has been significantly facilitated by microarray analysis and quantitative real-time RT-PCR. Microarray analysis offers the advantage of profiling expression levels of hundreds or thousands...

Diamond Film May Enable Critical New Sensors For Bioterror

MADISON - In this time of the chronic threat of terrorism and the possibility of war with an adversary who may be armed with biological weapons, high on the wish list of security agencies and battlefield commanders is a quick and easy way to detect the presence of dangerous biological agents. Now, with the help of a novel diamond film developed by chemists at the University of Wisconsin-...

MicroRNA Profiling by Array Analysis Reveals Critical BioMarkers

Jaclyn Shingara, Kerri Keiger, Ila Wolf, Jeffrey Shelton, Emmanuel Labourier, and David Brown R&D Division, Ambion, Inc. MicroRNAs (miRNAs) are small, siRNA-like molecules, encoded in the genomes of plants and animals,...

Chicago-Milwaukee "mega-metro" infrastructure improvements are critical

There are already commuters from Wi...

Caden Biosciences may signal critical mass

But as area biotech leaders and venture capitalists convened Tuesday to welcome an emerging drug disc...

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Critical at Medicine News

Cells critical for asthma development found

Researchers have found that mice lacking a specific immune cell are unable to develop asthma. Asthma is as a result of airway hyper-reactivity (AHR) which is narrowing of the tiny passages in the lungs in response to a trigger such as house dust mite. AHR is triggered by the immune system and leads to the characteristic wheezing and coughing symptoms of an asthma attack. Researchers at Stanford U...

Ultrasound Screening Could Improve The Outcome Of Critically ill Patients

New research finds ultrasound screening is cost effective and could help in the prevention of blood clots or venous thrombosis.The research focuses on patients who have a catheter in the main artery in their thigh called the femoral artery.// Almost half of the 31 million patients admitted into the intensive care unit each year receive a central venous catheter. It’s estimated femoral vein...

Sleep Not Critical For Early Brain Development Of Baby Dolphins

Sleep is an important component of mammal’s daily life and more so of newborn babies who in their first month of // gestation are known to sleep for over 18 hours. However, it is different with some of the mammals living in the sea. It has been reported in Nature that newborn bottlenose dolphins and killer whales are wake most of the time in the first month. Their moms manage with only a wink or...

Critically Ill Patients More At Risk Of Infection If Glucose Is Present In Their Lung Secretions

Patients in ICU have increased risk of picking up infections like MRSA if they glucose in their lung secretions. The study was published in the recent issue of the journal Thorax.// The authors base their findings on a study of 98 critically ill patients in intensive care who required mechanical help with their breathing for more than 48 hours. The patients were drawn from medical and...

Dietary supplementation of Folic Acid Requires Critical Evaluation

Neural tube defects are congenital deformities that arise in the closure of the nervous system. Spina bifida and anencephaly are the two most common forms of neural tube defects seen. // The defect causes paralysis in spina bifida and fatal brain deformation in anencephaly. Although the defect can be diagnosed by antenatal ultrasound, nothing much can be done to correct the defect. The c...

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Critical at Medicine Products

Rapidlink Critical Care Information Management System

Description:Today, the importance of electronic connectivity for blood gas testing is well understood. Transmission of patient results is critical for patient care, records, and billing. A sound quality assurance program that includes connectivity is essential to ensure analyzers are operating properly....
Company:Siemens Medical Solutions Diagnostics

Statscan Critical Imaging System

Description:The Statscan Critical Imaging System is a flexible format digital radiography (DR) system aimed specifically at the needs of emergency medical centers and is designed to meet the radiography needs of both trauma patients and standard emergency patients. Statscan gives critical life-saving information to the medical staff by enabling them to have a complete pictureliterally from head to toeof a pa...
Company:Lodox Systems

Stat Profile Critical Care Xpress

Description:Stat Profile Critical Care Xpress is an innovative, stat analyzer that measures blood gases, electrolytes, chemistry, and hematology with on-board co-oximetry and integrated data management "all in one single, compact instrument. Measured tests include pH, PCO %, hematocrit and hemoglobin, sodium, potassium, chloride, ionized calcium, ionized magnesium,...
Company:Nova Biomedical

S/5 Compact Critical Care Monitor

Description:Flexible, modular, easy to use. The S/5 Compact Critical Care Monitor is a modular, small-footprint monitor ideally suited for medium care monitoring. The monitor uses standard S/5 measurement modules and Datex-Ohmeda supplies and accessories. The S/5 Compact Critical Care Monitor shares the same user interface and features as the S/5 Critical Care Monitor. Its large 12.1"active...
Company:Datex-Ohmeda, Inc.

S/5 Critical Care Monitor

Description:Meeting the critical care challenge. The S/5 Critical Care Monitor is a multiparameter monitor that offers a flexible solution for the varying needs of critical care. The S/5 Critical Care Monitor provides a variety of parameter module options, display and mounting options, remote control and extension frame to let you optimize the bedside set-up to help meet your needs. The new 15" flat...
Company:Datex-Ohmeda, Inc.

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Critical at Medicine Technology

NIEHS Researchers Identify Enzyme Critical in DNA Replication

BETHESDA, Md., July 5, 2007--In this weeks issue of Science,researchers from the National Institute of Environmental HealthSciences (NIEHS) and Umeö University in Sweden report animportant discovery about a critical new role that an enzyme calledDNA polymerase epsilon plays in replicating DNA in higher organismssuch as yeast and perhaps even humans. The study places us one ste...

Velcade (bortezomib) for Injection Based Induction Therapy Delivered High Post-Transplant Complete Remission Rate, a Critical Marker for Increased Overall Survival

- New Data from Phase III Intergroupe Francophone du Myelome (IFM)Trial Presented During IMW - CAMBRIDGE, Mass., July 02, 2007 /PRNewswire-FirstCall/ --Millennium Pharmaceuticals, Inc. today reported that new data werepresented on the comparative Phase III clinical trial evaluating aVELCADE based therapy in newly diagnosed multiple myeloma (MM)patients. As induction therapy prior to stem...

Critical Therapeutics Announces the Publication of Data for ZyfloCR (Zileuton) Extended-Release Tablets in the Journal of Asthma

LEXINGTON, Mass.--(BUSINESS WIRE)--Jun 12, 2007 - CriticalTherapeutics, Inc. (Nasdaq: CRTX) today announced the publicationof data from a pivotal Phase III clinical trial of ZYFLO CR(TM)(zileuton) extended-release tablets in the June 2007 issue of theJournal of Asthma. ZYFLO CR was approved by the U.S. Food and DrugAdministration (FDA) on May 30, 2007. Critical Therapeutics,together with it...

New Critical Path Report Highlights Research Needed to Foster Generic Drug Development

ROCKVILLE, Md., May 2, 2007-The U.S. Food and DrugAdministration (FDA) today issued the "<a target="_blank" href="http://www.fda.gov/oc/initiatives/criticalpath/reports/generic.html">CriticalPath Opportunities for Generic Drugs " report identifying manyof the unanswered scientific questions that impede the developmentof generic versions of commonly used drugs. The report is part...

Critical Therapeutics Announces the Publication of New Preclincial HMGB1 Data in Nature Immunology

LEXINGTON, Mass.--(BUSINESS WIRE)--Apr 18, 2007 - CriticalTherapeutics, Inc. (Nasdaq: CRTX) today announced that newpreclinical research demonstrating a role in chronic inflammatoryautoimmune disease for High Mobility Group Box-1 protein (HMGB1), apro-inflammatory mediator and nuclear DNA-binding protein, will bepublished in the May 2007 issue of Nature Immunology. Thepublication demonstrat...

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